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Volumn 88, Issue 7, 2010, Pages 746-753

Inhibition of proteolysis of Delta-like-1 does not promote or reduce T-cell developmental potential

Author keywords

Delta; development; Notch; protease; T cell; thymus

Indexed keywords

ADAM PROTEIN; MEMBRANE PROTEIN; NOTCH RECEPTOR; PROTEIN DELTA LIKE 1; UNCLASSIFIED DRUG;

EID: 77957853390     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.30     Document Type: Article
Times cited : (7)

References (52)
  • 3
    • 0035179878 scopus 로고    scopus 로고
    • Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling
    • Anderson G, Pongracz J, Parnell S, Jenkinson EJ. Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling. Eur J Immunol 2001; 31: 3349-3354.
    • (2001) Eur J Immunol , vol.31 , pp. 3349-3354
    • Anderson, G.1    Pongracz, J.2    Parnell, S.3    Jenkinson, E.J.4
  • 4
    • 0033867521 scopus 로고    scopus 로고
    • A ligandinduced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1
    • Mumm JS, Schroeter EH, Saxena MT, Griesemer A, Tian X, Pan DJ et al. A ligandinduced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. Mol Cell 2000; 5: 197-206.
    • (2000) Mol Cell , vol.5 , pp. 197-206
    • Mumm, J.S.1    Schroeter, E.H.2    Saxena, M.T.3    Griesemer, A.4    Tian, X.5    Pan, D.J.6
  • 5
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: Unfolding the activation mechanism
    • Kopan R, Ilagan MX. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009; 137: 216-233.
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 6
    • 46449089731 scopus 로고    scopus 로고
    • ADAM proteases: Ligand processing and modulation of the Notch pathway
    • Zolkiewska A. ADAM proteases: ligand processing and modulation of the Notch pathway. Cell Mol Life Sci 2008; 65: 2056-2068.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2056-2068
    • Zolkiewska, A.1
  • 7
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray SJ. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 2006; 7: 678-689.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 8
    • 0031846155 scopus 로고    scopus 로고
    • Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development
    • Klueg KM, Parody TR, Muskavitch MA. Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development. Mol Biol Cell 1998; 9: 1709-1723.
    • (1998) Mol Biol Cell , vol.9 , pp. 1709-1723
    • Klueg, K.M.1    Parody, T.R.2    Muskavitch, M.A.3
  • 9
    • 34347329150 scopus 로고    scopus 로고
    • RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity
    • Muraguchi T, Takegami Y, Ohtsuka T, Kitajima S, Chandana EP, Omura A et al. RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity. Nat Neurosci 2007; 10: 838-845.
    • (2007) Nat Neurosci , vol.10 , pp. 838-845
    • Muraguchi, T.1    Takegami, Y.2    Ohtsuka, T.3    Kitajima, S.4    Chandana, E.P.5    Omura, A.6
  • 10
    • 59549090181 scopus 로고    scopus 로고
    • The role of Delta-like 1 shedding in muscle cell self-renewal and differentiation
    • Sun D, Li H, Zolkiewska A. The role of Delta-like 1 shedding in muscle cell self-renewal and differentiation. J Cell Sci 2008; 121: 3815-3823.
    • (2008) J Cell Sci , vol.121 , pp. 3815-3823
    • Sun, D.1    Li, H.2    Zolkiewska, A.3
  • 11
    • 0030882580 scopus 로고    scopus 로고
    • Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila
    • Sun X, Artavanis-Tsakonas S. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development 1997; 124: 3439-3448.
    • (1997) Development , vol.124 , pp. 3439-3448
    • Sun, X.1    Artavanis-Tsakonas, S.2
  • 13
    • 0141817915 scopus 로고    scopus 로고
    • The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments
    • LaVoie MJ, Selkoe DJ. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments. J Biol Chem 2003; 278: 34427-34437.
    • (2003) J Biol Chem , vol.278 , pp. 34427-34437
    • Lavoie, M.J.1    Selkoe, D.J.2
  • 14
    • 0032923759 scopus 로고    scopus 로고
    • Processing of the notch ligand delta by the met alloprotease Kuzbanian
    • Qi H, Rand MD, Wu X, Sestan N, Wang W, Rakic P et al. Processing of the notch ligand delta by the met alloprotease Kuzbanian. Science 1999; 283: 91-94.
    • (1999) Science , vol.283 , pp. 91-94
    • Qi, H.1    Rand, M.D.2    Wu, X.3    Sestan, N.4    Wang, W.5    Rakic, P.6
  • 16
    • 0034532698 scopus 로고    scopus 로고
    • Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling
    • Varnum-Finney B, Wu L, Yu M, Brashem-Stein C, Staats S, Flowers D et al. Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling. J Cell Sci 2000; 113 (Part 23): 4313-4318.
    • (2000) J Cell Sci , vol.113 , Issue.PART 23 , pp. 4313-4318
    • Varnum-Finney, B.1    Wu, L.2    Yu, M.3    Brashem-Stein, C.4    Staats, S.5    Flowers, D.6
  • 17
    • 13444283768 scopus 로고    scopus 로고
    • Unidirectional Notch signaling depends on continuous cleavage of Delta
    • Sapir A, Assa-Kunik E, Tsruya R, Schejter E, Shilo BZ. Unidirectional Notch signaling depends on continuous cleavage of Delta. Development 2005; 132: 123-132.
    • (2005) Development , vol.132 , pp. 123-132
    • Sapir, A.1    Assa-Kunik, E.2    Tsruya, R.3    Schejter, E.4    Shilo, B.Z.5
  • 18
    • 0037424348 scopus 로고    scopus 로고
    • The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent 'gamma-secretase' cleavage
    • Ikeuchi T, Sisodia SS. The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent 'gamma-secretase' cleavage. J Biol Chem 2003; 278: 7751-7754.
    • (2003) J Biol Chem , vol.278 , pp. 7751-7754
    • Ikeuchi, T.1    Sisodia, S.S.2
  • 19
    • 0038610845 scopus 로고    scopus 로고
    • The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase
    • Six E, Ndiaye D, Laabi Y, Brou C, Gupta-Rossi N, Israel A et al. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase. Proc Natl Acad Sci USA 2003; 100: 7638-7643.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7638-7643
    • Six, E.1    Ndiaye, D.2    Laabi, Y.3    Brou, C.4    Gupta-Rossi, N.5    Israel, A.6
  • 20
    • 0034161309 scopus 로고    scopus 로고
    • A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells
    • Han W, Ye Q, Moore MA. A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells. Blood 2000; 95: 1616-1625.
    • (2000) Blood , vol.95 , pp. 1616-1625
    • Han, W.1    Ye, Q.2    Moore, M.A.3
  • 21
    • 35048832766 scopus 로고    scopus 로고
    • Suppression of ADAM 10-induced Delta-1 shedding inhibits cell proliferation during the chondro-inhibitory action of TGF-beta3
    • Jin EJ, Choi YA, Sonn JK, Kang SS. Suppression of ADAM 10-induced Delta-1 shedding inhibits cell proliferation during the chondro-inhibitory action of TGF-beta3. Mol Cells 2007; 24: 139-147.
    • (2007) Mol Cells , vol.24 , pp. 139-147
    • Jin, E.J.1    Choi, Y.A.2    Sonn, J.K.3    Kang, S.S.4
  • 22
    • 0037648484 scopus 로고    scopus 로고
    • Notch-induced proteolysis and nuclear localization of the Delta ligand
    • Bland CE, Kimberly P, Rand MD. Notch-induced proteolysis and nuclear localization of the Delta ligand. J Biol Chem 2003; 278: 13607-13610.
    • (2003) J Biol Chem , vol.278 , pp. 13607-13610
    • Bland, C.E.1    Kimberly, P.2    Rand, M.D.3
  • 23
    • 33847637224 scopus 로고    scopus 로고
    • The Delta intracellular domain mediates TGF-beta/activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway
    • Hiratochi M, Nagase H, Kuramochi Y, Koh CS, Ohkawara T, Nakayama K. The Delta intracellular domain mediates TGF-beta/activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway. Nucleic Acids Res 2007; 35: 912-922.
    • (2007) Nucleic Acids Res , vol.35 , pp. 912-922
    • Hiratochi, M.1    Nagase, H.2    Kuramochi, Y.3    Koh, C.S.4    Ohkawara, T.5    Nakayama, K.6
  • 24
    • 26844491357 scopus 로고    scopus 로고
    • The intracellular domain of Notch ligand Delta1 induces cell growth arrest
    • Kolev V, Kacer D, Trifonova R, Small D, Duarte M, Soldi R et al. The intracellular domain of Notch ligand Delta1 induces cell growth arrest. FEBS Lett 2005; 579: 5798-5802.
    • (2005) FEBS Lett , vol.579 , pp. 5798-5802
    • Kolev, V.1    Kacer, D.2    Trifonova, R.3    Small, D.4    Duarte, M.5    Soldi, R.6
  • 25
    • 0842324623 scopus 로고    scopus 로고
    • Multiple niches for Notch in cancer: Context is everything
    • Weng AP, Aster JC. Multiple niches for Notch in cancer: context is everything. Curr Opin Genet Dev 2004; 14: 48-54.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 48-54
    • Weng, A.P.1    Aster, J.C.2
  • 26
    • 0033136717 scopus 로고    scopus 로고
    • Deficient T cell fate specification in mice with an induced inactivation of Notch1
    • Radtke F, Wilson A, Stark G, Bauer M, van Meerwijk J, MacDonald HR et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 1999; 10: 547-558.
    • (1999) Immunity , vol.10 , pp. 547-558
    • Radtke, F.1    Wilson, A.2    Stark, G.3    Bauer, M.4    Van Meerwijk, J.5    MacDonald, H.R.6
  • 27
    • 18944406380 scopus 로고    scopus 로고
    • Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1
    • Manilay JO, Anderson AC, Kang C, Robey EA. Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1. J Immunol 2005; 174: 6732-6741.
    • (2005) J Immunol , vol.174 , pp. 6732-6741
    • Manilay, J.O.1    Anderson, A.C.2    Kang, C.3    Robey, E.A.4
  • 28
    • 53749096966 scopus 로고    scopus 로고
    • ADAM10 is essential for proteolytic activation of Notch during thymocyte development
    • Tian L, Wu X, Chi C, Han M, Xu T, Zhuang Y. ADAM10 is essential for proteolytic activation of Notch during thymocyte development. Int Immunol 2008; 20: 1181-1187.
    • (2008) Int Immunol , vol.20 , pp. 1181-1187
    • Tian, L.1    Wu, X.2    Chi, C.3    Han, M.4    Xu, T.5    Zhuang, Y.6
  • 29
    • 33947629847 scopus 로고    scopus 로고
    • Non-cell autonomous expression of TNF-\{alpha\}-converting enzyme ADAM17 is required
    • Li N, Boyd K, Dempsey PJ, Vignali DA. Non-cell autonomous expression of TNF-\{alpha\}-converting enzyme ADAM17 is required. J Immunol 2007; 178: 4214-4221.
    • (2007) J Immunol , vol.178 , pp. 4214-4221
    • Li, N.1    Boyd, K.2    Dempsey, P.J.3    Vignali, D.A.4
  • 30
    • 0036070308 scopus 로고    scopus 로고
    • Inactivation of Notch1 impairs VDJ beta rearrangement and allows pre-TCR-independent survival of early alpha beta lineage thymocytes
    • Wolfer A, Wilson A, Nemir M, MacDonald HR, Radtke F. Inactivation of Notch1 impairs VDJ beta rearrangement and allows pre-TCR-independent survival of early alpha beta lineage thymocytes. Immunity 2002; 16: 869-879.
    • (2002) Immunity , vol.16 , pp. 869-879
    • Wolfer, A.1    Wilson, A.2    Nemir, M.3    MacDonald, H.R.4    Radtke, F.5
  • 31
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • Schmitt TM, Zuniga-Pflucker JC. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 2002; 17: 749-756.
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 32
    • 33645050124 scopus 로고    scopus 로고
    • T-cell development, doing it in a dish
    • Schmitt TM, Zuniga-Pflucker JC. T-cell development, doing it in a dish. Immunol Rev 2006; 209: 95-102.
    • (2006) Immunol Rev , vol.209 , pp. 95-102
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 33
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey DI, Kennedy J, Suda T, Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol 1993; 150: 4244-4252.
    • (1993) J Immunol , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 35
    • 0036467663 scopus 로고    scopus 로고
    • Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
    • Reizis B, Leder P. Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway. Genes Dev 2002; 16: 295-300.
    • (2002) Genes Dev , vol.16 , pp. 295-300
    • Reizis, B.1    Leder, P.2
  • 36
    • 41949087056 scopus 로고    scopus 로고
    • Notch target Hes5 ensures appropriate Notch induced T-versus B-cell choices in the thymus
    • Varnum-Finney B, Dallas MH, Kato K, Bernstein ID. Notch target Hes5 ensures appropriate Notch induced T-versus B-cell choices in the thymus. Blood 2008; 111: 2615-2620.
    • (2008) Blood , vol.111 , pp. 2615-2620
    • Varnum-Finney, B.1    Dallas, M.H.2    Kato, K.3    Bernstein, I.D.4
  • 37
    • 33646551228 scopus 로고    scopus 로고
    • Multiple functions of Notch signaling in self-renewing organs and cancer
    • Wilson A, Radtke F. Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Lett 2006; 580: 2860-2868.
    • (2006) FEBS Lett , vol.580 , pp. 2860-2868
    • Wilson, A.1    Radtke, F.2
  • 38
    • 0028048369 scopus 로고
    • Generation of lymphohematopoietic cells from embryonic stem cells in culture
    • Nakano T, Kodama H, Honjo T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 1994; 265: 1098-1101.
    • (1994) Science , vol.265 , pp. 1098-1101
    • Nakano, T.1    Kodama, H.2    Honjo, T.3
  • 39
    • 0030590652 scopus 로고    scopus 로고
    • Flow cytometric identification of murine neutrophils and monocytes
    • Lagasse E, Weissman IL. Flow cytometric identification of murine neutrophils and monocytes. J Immunol Methods 1996; 197: 139-150.
    • (1996) J Immunol Methods , vol.197 , pp. 139-150
    • Lagasse, E.1    Weissman, I.L.2
  • 40
    • 16644386953 scopus 로고    scopus 로고
    • Soluble form of Jagged1: Unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation
    • Aho S. Soluble form of Jagged1: unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation. J Cell Biochem 2004; 92: 1271-1281.
    • (2004) J Cell Biochem , vol.92 , pp. 1271-1281
    • Aho, S.1
  • 41
    • 0442294193 scopus 로고    scopus 로고
    • The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins
    • Chen N, Greenwald I. The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins. Dev Cell 2004; 6: 183-192.
    • (2004) Dev Cell , vol.6 , pp. 183-192
    • Chen, N.1    Greenwald, I.2
  • 42
    • 0037382141 scopus 로고    scopus 로고
    • Fine-tuning Notch1 activation by endocytosis and glycosylation
    • Koch U, Yuan JS, Harper JA, Guidos CJ. Fine-tuning Notch1 activation by endocytosis and glycosylation. Semin Immunol 2003; 15: 99-106.
    • (2003) Semin Immunol , vol.15 , pp. 99-106
    • Koch, U.1    Yuan, J.S.2    Harper, J.A.3    Guidos, C.J.4
  • 43
    • 0037198653 scopus 로고    scopus 로고
    • Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations
    • Kawamata S, Du C, Li K, Lavau C. Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations. Oncogene 2002; 21: 3855-3863.
    • (2002) Oncogene , vol.21 , pp. 3855-3863
    • Kawamata, S.1    Du, C.2    Li, K.3    Lavau, C.4
  • 44
    • 67650660754 scopus 로고    scopus 로고
    • The Notch signaling pathway: Transcriptional regulation at Notch target genes
    • Borggrefe T, Oswald F. The Notch signaling pathway: transcriptional regulation at Notch target genes. Cell Mol Life Sci 2009; 66: 1631-1646.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1631-1646
    • Borggrefe, T.1    Oswald, F.2
  • 45
    • 18644363680 scopus 로고    scopus 로고
    • Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells
    • Dallas MH, Varnum-Finney B, Delaney C, Kato K, Bernstein ID. Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells. J Exp Med 2005; 201: 1361-1366.
    • (2005) J Exp Med , vol.201 , pp. 1361-1366
    • Dallas, M.H.1    Varnum-Finney, B.2    Delaney, C.3    Kato, K.4    Bernstein, I.D.5
  • 46
    • 58149154746 scopus 로고    scopus 로고
    • Delta-like 4 is indispensable in thymic environment specific for T cell development
    • Hozumi K, Mailhos C, Negishi N, Hirano K, Yahata T, Ando K et al. Delta-like 4 is indispensable in thymic environment specific for T cell development. J Exp Med 2008; 205: 2507-2513.
    • (2008) J Exp Med , vol.205 , pp. 2507-2513
    • Hozumi, K.1    Mailhos, C.2    Negishi, N.3    Hirano, K.4    Yahata, T.5    Ando, K.6
  • 47
    • 58149151302 scopus 로고    scopus 로고
    • Deltalike 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
    • Koch U, Fiorini E, Benedito R, Besseyrias V, Schuster-Gossler K, Pierres M et al. Deltalike 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J Exp Med 2008; 205: 2515-2523.
    • (2008) J Exp Med , vol.205 , pp. 2515-2523
    • Koch, U.1    Fiorini, E.2    Benedito, R.3    Besseyrias, V.4    Schuster-Gossler, K.5    Pierres, M.6
  • 48
    • 13544262340 scopus 로고    scopus 로고
    • Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro
    • La Motte-Mohs RN, Herer E, Zuniga-Pflucker JC. Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro. Blood 2005; 105: 1431-1439.
    • (2005) Blood , vol.105 , pp. 1431-1439
    • La Motte-Mohs, R.N.1    Herer, E.2    Zuniga-Pflucker, J.C.3
  • 49
    • 33646008578 scopus 로고    scopus 로고
    • Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors
    • de Pooter RF, Schmitt TM, de la Pompa JL, Fujiwara Y, Orkin SH, Zuniga-Pflucker JC. Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors. J Immunol 2006; 176: 5267-5275.
    • (2006) J Immunol , vol.176 , pp. 5267-5275
    • De Pooter, R.F.1    Schmitt, T.M.2    De La Pompa, J.L.3    Fujiwara, Y.4    Orkin, S.H.5    Zuniga-Pflucker, J.C.6
  • 52
    • 0027236954 scopus 로고
    • Production of high-titer helperfree retroviruses by transient transfection
    • Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helperfree retroviruses by transient transfection. Proc Natl Acad Sci USA 1993; 90: 8392-8396.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4


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