Synthesis and Identification of a new class of antileukemic agents containing 2-(arylcarboxamide)-(S)-6-amino-4,5,6,7-tetrahydrobenzo[d]thiazole

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 5331-5336

  Prasanna, D S ^a   Kavitha, C V ^b   Vinaya, K ^a   Ranganatha, S R ^b   Raghavan, Sathees C ^b   Rangappa, K S ^a  

^a UNIVERSITY OF MYSORE   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Apoptosis; Cancer therapeutics; Cytotoxicity; Leukemia; Tetrahydrobenzo d thiazole

Indexed keywords

2 (ARYLCARBOXAMIDE) 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOLE; 2,6 DIAMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOLE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOLE; AMIDE; ANTILEUKEMIC AGENT; ARYL CARBOXAMIDE; BENZAMIDE DERIVATIVE; BENZENE DERIVATIVE; LACTATE DEHYDROGENASE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 2 FLUOROBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 2,4 DICHLOROBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 2,6 DIFLUOROBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 3 BROMOBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 3 METHOXYBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 3,5 DINITROBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL) 4 TERT BUTYLBENZAMIDE; N ( 6 AMINO 4,5,6,7 TETRAHYDROBENZO[D]THIAZOL 2 YL)BENZAMIDE; PHENYL GROUP; THIAZOLE DERIVATIVE; TRYPAN BLUE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE ARREST; CELL PROLIFERATION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG SYNTHESIS; ENZYME ASSAY; HUMAN; HUMAN CELL; LEUKEMIA CELL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

CELL LINE, TUMOR; HUMANS; LEUKEMIA; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 77957838582     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.08.056     Document Type: Article

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