Antitumour benzothiazoles. Part 20: 3′-cyano and 3′-alkynyl-substituted 2-(4′-aminophenyl)benzothiazoles as new potent and selective analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 3, 2003, Pages 471-474

  Hutchinson, Ian ^a   Bradshaw, Tracey D ^a   Matthews, Charles S ^a   Stevens, Malcolm F G ^a   Westwell, Andrew D ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY;

ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; HUMANS; INDICATORS AND REAGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0037325622     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00930-7     Document Type: Article

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2. Shi D.-F., Bradshaw T.D., Wrigley S., McCall C.J., Lelieveld P., Fichtner I., Stevens M.F.G. J. Med. Chem. 39:1996;3375.
3. Bradshaw T.D., Wrigley S., Shi D.-F., Schultz R.J., Paull K.D., Stevens M.F.G. Brit. J. Cancer. 77:1998;745.
4. Bradshaw T.D., Shi D.-F., Schultz R.J., Paull K.D., Kelland L., Wilson A., Garner C., Fiebig H.H., Wrigley S., Stevens M.F.G. Brit. J. Cancer. 78:1998;421.
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7. Kashiyama E., Hutchinson I., Chua M.-S., Stinson S.F., Phillips L.R., Kaur G., Sausville E.A., Bradshaw T.D., Westwell A.D., Stevens M.F.G. J. Med. Chem. 42:1999;4172.
8. Hutchinson I., Chua M.-S., Browne H.L., Trapani V., Bradshaw T.D., Westwell A.D., Stevens M.F.G. J. Med. Chem. 44:2001;1446.
9. Hutchinson I., Stevens M.F.G., Westwell A.D. Tetrahedron Lett. 41:2000;425.
10. Hutchinson I., Jennings S.A., Vishnuvajjala B.R., Westwell A.D., Stevens M.F.G. J. Med. Chem. 45:2002;744.
11. 2).
12. 2), 3.46 (1H, s, C≡CH).