RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors

Experimental Biology and Medicine

Volumn 235, Issue 10, 2010, Pages 1269-1276

  Bell Jr , Anthony J ^a   Fegen, David ^b   Ward, Maureen ^c   Bank, Arthur ^c  

^a The University of Southern Mississippi   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Envelope proteins; Gene delivery; Gene therapy; Lentiviral vectors; RD114

Indexed keywords

ENVELOPE PROTEIN; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; RD114 PROTEIN; UNCLASSIFIED DRUG; G PROTEIN, VESICULAR STOMATITIS VIRUS; MEMBRANE PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS RECEPTOR;

ARTICLE; CENTRIFUGATION; CHIMERA; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION SYSTEM; GENE TRANSFER; GENETIC TRANSFECTION; HOST CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PACKAGING; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STABILITY; PSEUDOTYPING; SUPERNATANT; TRANSIENT TRANSFECTION; VESICULAR STOMATITIS VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE; WART VIRUS; CELL LINE; GENE THERAPY; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HELA CELL LINE; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; LENTIVIRINAE; PHYSIOLOGY; PLASMID; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN PAPILLOMAVIRUS; VESICULAR STOMATITIS VIRUS;

CELL LINE; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HELA CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; IN VITRO TECHNIQUES; LENTIVIRUS; MEMBRANE GLYCOPROTEINS; PLASMIDS; RECEPTORS, VIRUS; TRANSDUCTION, GENETIC; VIRAL ENVELOPE PROTEINS;

EID: 77957825561     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2010.010053     Document Type: Article

References (49)

1. Uchida N, Sutton R, Friera A, He D, Reitsman M, Chang W, Veres G, Scollay R, Wessman I. HIV, not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells. Proc Natl Acad Sci USA 1998;95:11939-44
2. Miyoshi H, Smith KA, Mosier DE, Verma IM, Torbett BE. Efficient transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. Science 1999;272:682-6
3. Naldini L, Blomer U, Gage FH, Trono D, Verma IM. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA 1996;93:11382-8 (Pubitemid 26347130)
4. Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 1997;15:871-5
5. Kordower JH, Bloch J, Ma SY, Chu Y, Palfi S, Roitberg BZ, Emborg M, Hantraye P, Deglon N, Aebischer P. Lentiviral gene transfer to the nonhuman primate brain. Exp Neurol 1999;160:1-16
6. Johnson LG, Olsen JC, Naldini L, Boucher RC. Pseudotyped human lentiviral vector-mediated gene transfer to airway epithelia in vivo. Gene Ther 2000;7:568-74 (Pubitemid 30175559)
7. May C, Rivella S, Callegari J, Heller G, Gaensler KM, Luzzatto L, Sadelain M. Therapeutic haemoglobin synthesis in beta-thalassemic mice expressing lentivirus-encoded human beta-globin. Nature 2000;406:82-6
8. Pawliuk R, Westerman KA, Fabry ME, Payen E, Tighe R, Bouhassira EE, Acharya SA, Ellis J, London IM, Eaves CJ, Humphries RK, Beuzard Y, Nagel RL, Leboulch P. Correction of sickle cell disease in transgenic mouse models by gene therapy. Science 2001;294:2368-71
9. Levasseur DN, Ryan TM, Pawlik KM, Townes TM. Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells. Blood 2003;102:4312-9
10. Seganti L, Superti F, Girmenia C, Melucci L, Orsi N. Study of receptors for vesicular stomatitis virus in vertebrate and invertebrate cells. Microbiologica 1986;9:259-67
11. Burns J, Friedmann T, Driever W, Burrascano M, Yee J. Vesicular stomatitis G gylcoprotein pseudotyped lentiviral vectors: concentration to very high titers and efficient gene expression in mammalian and non-mammalian cells. Proc Natl Acad Sci USA 1993;90:8033-7 (Pubitemid 23260849)
12. Sinn PL, Sauter SL, McCray PB Jr. Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors-design, biosafety, and production. Gene Ther 2005;12:1089-98
13. Yee JK, Miyanohara A, LaPorte P, Bouic K, Burns JC, Friedmann T. A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. Proc Natl Acad Sci USA 1994;91:9564-8 (Pubitemid 24297955)
14. Yang Y, Vanin EF, Whitt MA, Fornerod M, Zwart R, Schneiderman RD, Grosveld G, Nienhuis AW. Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein. Hum Gene Ther 1995;6:1203-13
15. Kaplan AH, Swantsrom R. The HIV-1 gag precursor is processed via two pathways: implications for cytoxicity. Biomed Biochem Acta 1991;50:647-53
16. Kaplan AH, Swantsrom R. Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments. Proc Natl Acad Sci USA 1991;88:4528-32
17. Planelles V, Bachelerie F, Jowett JBM, Haislip A, Xie Y, Banooni P, Masuda T, Chen ISY. Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr. J Virology 1995;69:5883-9
18. Kaul M, Yu H, Ron Y, Dougherty JP. Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences. Virology 1998;249:167-74 (Pubitemid 28430918)
19. Kafri T, van Praag H, Ouyang L, Gage FH, Verma IM. A packaging cell line for lentivirus vectors. J Virol 1999;73:576-84 (Pubitemid 28565401)
20. Klages N, Zufferey R, Trono D. A stable system for the high-titer production of multiply attenuated lentiviral vectors. Mol Ther 2000;2:170-6
21. Farson D, Witt R, McGuinness R, Dull T, Kelly M, Song J, Radeke R, Bukovsky A, Consiglio A, Naldini L. A new-generation stable inducible packaging cell line for lentiviral vectors. Hum Gene Ther 2001;12:981-97 (Pubitemid 32681861)
22. Ni Y, Sun S, Oparaocha I, Humeau L, Davis B, Cohen R, Binder G, Chang YN, Slepushkin V, Dropulic B. Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector. J Gene Med 2005;7:818-34 (Pubitemid 40872867)
23. Cockrell AS, Ma H, Fu K, McCown TJ, Kafri T. A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors. Mol Ther 2006;14:276-84
24. Broussau S, Jabbour N, Lachapelle G, Durocher Y, Tom R, Transfiguracion J, Gilbert R, Massie B. Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther 2008;16:500-7
25. Christodoulopoulos I, Cannon PM. Sequences in the cytoplasmic tail of the gibbon ape leukemia virus envelope protein that prevent its incorporation into lentivirus vectors. J Virol 2001;75:4129-38
26. Hanawa H, Kelly PF, Nathwani AC, Persons DA, Vandergriff JA, Hargrove P, Vanin EF, Nienhuis AW. Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood. Mol Ther 2002;5:242-51
27. Stitz J, Buchholz CJ, Engelstadter M, Uckert W, Bloemer U, Schmitt I, Cichutek K. Lentiviral vectors pseudotyped with envelope glycoproteins derived from gibbon ape leukemia virus and murine leukemia virus 10A1. Virology 2000;273:16-20 (Pubitemid 30602003)
28. Strang BL, Ikeda Y, Cosset FL, Collins MK, Takeuchi Y. Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells. Gene Ther 2004;11:591-8 (Pubitemid 38455977)
29. Medina MF, Kobinger GP, Rux J, Gasmi M, Looney DJ, Bates P, Wilson JM. Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung. Mol Ther 2003;8:777-89 (Pubitemid 37527453)
30. Sandrin V, Boson B, Salmon P, Gay W, Negre D, Le Grand R, Trono D, Cosset FL. Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates. Blood 2002;100:823-32
31. Bouard D, Sandrin V, Boson B, Negre D, Thomas G, Granier C, Cosset FL. An acidic cluster of the cytoplasmic tail of the RD114 virus glycoprotein controls assembly of retroviral envelopes. Traffic 2007;8:835-47 (Pubitemid 46971631)
32. Zhang XY, La Russa VF, Reiser J. Transduction of bone-marrow-derived mesenchymal stem cells by using lentivirus vectors pseudotyped with modified RD114 envelope glycoproteins. J Virol 2004;78:1219-29 (Pubitemid 38095832)
33. Rasko JE, Battini JL, Gottschalk RJ, Mazo I, Miller AD. The RD114/simian type D retrovirus receptor is a neutral amino acid transporter. Proc Natl Acad Sci USA 1999;96:2129-34 (Pubitemid 29117879)
34. Tailor CS, Nouri A, Zhao Y, Takeuchi Y, Kabat D. A sodium-dependent neutral-amino-acid transporter mediates infections of feline and baboon endogenous retroviruses and simian type D retroviruses. J Virol 1999;73:4470-4 (Pubitemid 29189898)
35. Green BJ, Lee SC, Rasko JE. Biodistribution of the RD114/mammalian type D retrovirus receptor, RDR. J Gene Med 2004;6:249-59
36. Galin J, Melkus M, Padett A, Kelly P, Garcia J. Engraftment of NOD/SCID mice with human CD34+ cells transduced by concentrated vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. J Virol 2001;75:9995-9
37. Ward M, Sattler R, Grossman IR, Bell AJ Jr, Skerrett D, Baxi L, Bank A. A stable murine-based RD114 retroviral packaging line efficiently transduces human hematopoietic cells. Mol Ther 2003;8:804-12
38. Ikeda Y, Takeuchi Y, Martin F, Cosset FL, Mitrophanous K, Collins M. Continuous high-titer HIV-1 vector production. Nat Biotechnol 2003;21:569-72
39. Landau NR, Littman DR. Packaging system for rapid production of murine leukemia virus vectors with variable tropism. J Virol 1992;66:5110-3
40. Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 1993;90:8392-6
41. Finer MH, Dull TJ, Qin L, Farson D, Roberts MR. kat: a high-efficiency retroviral transduction system for primary human T lymphocytes. Blood 1994;83:43-50 (Pubitemid 24016514)
42. Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996;272:263-7
43. Zennou V, Petit C, Guetard D, Nerhbass U, Montagnier L, Charneau P. HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 2000;101:173-85 (Pubitemid 32004745)
44. Zennou V, Serguera C, Sarkis C, Colin P, Perret E, Mallet J, Charneau P. The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain. Nat Biotechnol 2001;19:446-50 (Pubitemid 32428287)
45. Logan AC, Nightingale SJ, Haas DL, Cho GJ, Pepper KA, Kohn DB. Factors influencing the titer and infectivity of lentiviral vectors. Hum Gene Ther 2004;15:976-88
46. Di Nunzio F, Piovani B, Cosset FL, Mavilio F, Stornaiuolo A. Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein. Hum Gene Ther 2007;18:811-20 (Pubitemid 47502847)
47. Slingsby JH, Baban D, Sutton J, Esapa M, Price T, Kingsman SM, Kingsman AJ, Slade A. Analysis of 4070A envelope levels in retroviral preparations and effect on target cell transduction efficiency. Hum Gene Ther 2000;11:1439-51
48. Arai T, Matsumoto K, Saitoh K, Ui M, Ito T, Murakami M, Kanegae Y, Saito I, Cosset FL, Takeuchi Y, Iba H. A new system for stringent, high-titer vesicular stomatitis virus G protein-pseudotyped retrovirus vector induction by introduction of Cre recombinase into stable prepackaging cell lines. J Virol 1998;72:1115-21
49. Throm RE, Ouma AA, Zhou S, Chandrasekaran A, Lockey T, Greene M, De Ravin SS, Moayeri M, Malech HL, Sorrentino BP, Gray JT. Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection. Blood 2009;13:5104-10