Regulated lentiviral packaging cell line devoid of most viral cis- acting sequences

Virology

Volumn 249, Issue 1, 1998, Pages 167-174

  Kaul, Malvika ^a,b   Yu, Hong ^a   Ron, Yacov ^a   Dougherty, Joseph P ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CIS ACTING ELEMENT; REGULATOR PROTEIN; RNA DIRECTED DNA POLYMERASE; STRUCTURAL PROTEIN; VIRUS PROTEIN;

ARTICLE; CELL LINE; CONTROLLED STUDY; DNA PACKAGING; GENE EXPRESSION SYSTEM; GENE TARGETING; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRINAE; PRIORITY JOURNAL; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; RNA VIRUSES;

EID: 0032530895     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9327     Document Type: Article

References (40)

1. Aiken C. Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A. J. Virol. 71:1997;5871-5877.
2. Bartz S. R., Rogel M. E., Emerman M. Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control. J. Virol. 70:1996;2324-2331.
3. Bartz S. R., Vodicka M. A. Production of high-titer human immunodeficiency virus type 1 pseudotyped with vesicular stomatitis virus glycoprotein. Methods. 12:1997;337-342.
4. Bernard H., Krammer G., Rowekamp W. G. Construction of a fusion gene that confers resistance against hygromycin B. Exp. Cell Res. 158:1985;237-243.
5. Blömer U., Naldini L., Kafri T., Trono D., Verma I. M., Gage F. H. Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J. Virol. 71:1997;6641-6649.
6. Chalfie M., Tu Y., Euskirchen G., Ward W. W., Prasher D. C. Green fluorescent protein as a marker for gene expression. Science. 263:1994;802-805.
7. Corbeau P., Kraus G., Wong-Staal F. Efficient gene transfer by a human immunodeficiency virus type 1 (HIV-1)-derived vector utilizing a stable HIV packaging cell line. Proc. Natl. Acad. Sci. USA. 93:1996;14070-14075.
8. DuBridge R. B., Tang P., Hsia H. C., Leong P. M., Miller J. H., Calos M. P. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol. Cell. Biol. 7:1987;379-387.
9. Emerman M., Temin H. M. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell. 39:1984;449-467.
10. Gallay P., Swingler S., Aiken C., Trono D. HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator. Cell. 80:1995a;379-388.
11. Gallay P., Swingler S., Song J., Bushman F., Trono D. HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase. Cell. 83:1995b;569-576.
12. Gervaix A., West D., Leoni L. M., Richman D. D., Wong-Staal F., Corbeil J. A new reporter cell line to monitor HIV infection and drug susceptibility in vitro. Proc. Natl. Acad. Sci. USA. 94:1997;4653-4658.
13. Gorman, C. 1985, DNA Cloning, 143, 190, IRL Press, Oxford.
14. Gossen M., Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA. 89:1992;5547-5551.
15. Harris J. D., Lemoine N. R. Strategies for targeted gene therapy. Trends Genet. 12:1996;400-405.
16. Hatch W. C., Tanaka K. E., Calvelli T., Rashbaum W. K., Kress Y., Lyman W. D. Persistent productive HIV-1 infection of a CD4-human fetal thymocyte line. J. Immunol. 148:1992;3055-3061.
17. Heinzinger N. K., Bukrinsky M. I., Haggerty S. A., Ragland A. M., Kewalramani V., Lee M. A., Gendelman H. E., Ratner L., Stevenson M., Emerman M. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proc. Natl. Acad. Sci. USA. 91:1994;7311-7315.
18. Jones H. W. Jr., McKusick V. A., Harper P. S., Wuu K. D. George Otto Gey. (1899-1970). The HeLa cell and a reappraisal of its origin. Obstet. Gynecol. 38:1971;945-949.
19. Kaplan A. H., Swanstrom R. The HIV-1 gag precursor is processed via two pathways: Implications for cytotoxicity. Biomed. Biochim. Acta. 50:1991;647-653.
20. Karacostas V., Nagashima K., Gonda M. A., Moss B. Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector. Proc. Natl Acad. Sci. USA. 86:1989;8964-8967.
21. Kim H. J., Lee K., O'Rear J. J. A short sequence upstream of the 5′ major splice site is important for encapsidation of HIV-1 genomic RNA. Virology. 198:1994;336-340.
22. Kimpton J., Emerman M. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J. Virol. 66:1992;2232-2239.
23. Koo H. M., Brown A. M., Kaufman R. J., Prorock C. M., Ron Y., Dougherty J. P. A spleen necrosis virus-based retroviral vector which expresses two genes from a dicistronic mRNA. Virology. 186:1992;669-675.
24. Lewis P. F., Emerman M. Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus. J. Virol. 68:1994;510-516.
25. Markowitz D., Goff S., Bank A. A safe packaging line for gene transfer: Separating viral genes on two different plasmids. J. Virol. 62:1988;1120-1124.
26. McBride M. S., Panganiban A. T. The human immunodeficiency virus type 1 encapsidation site is a multipartite RNA element composed of functional hairpin structures. J. Virol. 70:1996;2963-2973.
27. Miller D. G., Adam M. A., Miller A. D. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell. Biol. 10:1990;4239-4242.
28. Mulligan R. C., Berg P. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proc. Natl. Acad. Sci. USA. 78:1981;2072-2076.
29. Naldini L., Blomer U., Gage F. H., Trono D., Verma I. M. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc. Natl. Acad. Sci. USA. 93:1996a;11382-11388.
30. Naldini L., Blomer U., Gallay P., Ory D., Mulligan R., Gage F. H., Verma I. M., Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science. 272:1996b;263-267.
31. Page K. A., Stearns S. M., Littman D. R. Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity. J. Virol. 66:1992;524-533.
32. Poeschla E., Corbeau P., Wong-Staal F. Development of HIV vectors for anti-HIV gene therapy. Proc. Natl. Acad. Sci. USA. 93:1996;11395-11399.
33. Richardson J. H., Child L. A., Lever A. M. Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5′ leader region. J. Virol. 67:1993;3997-4005.
34. Robbins P. D., Tahara H., Ghivizzani S. C. Viral vectors for gene therapy. Trends Biotechnol. 16:1998;35-40.
35. Sambrook, J. Fritsch, E. F. Maniatis, T. 1989, Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
36. Sodroski J., Goh W. C., Rosen C., Campbell K., Haseltine W. A. Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity. Nature. 322:1986;470-474.
37. Srinivasakumar N., Chazal N., Helga-Maria C., Prasad S., Hammarskjold M. L., Rekosh D. The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines. J. Virol. 71:1997;5841-5848.
38. Willey R. L., Smith D. H., Lasky L. A., Theodore T. S., Earl P. L., Moss B., Capon D. J., Martin M. A. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:1988;139-147.
39. Yu H., Jetzt A. E., Dougherty J. P. Use of single-cycle analysis to study rates and mechanisms of retroviral mutation. Methods. 12:1997;325-336.
40. Yu H., Rabson A. B., Kaul M., Ron Y., Dougherty J. P. Inducible human immunodeficiency virus type 1 packaging cell lines. J. Virol. 70:1996;4530-4537.