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Volumn 45, Issue 11, 2010, Pages 4904-4913
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Synthesis, anti-inflammatory evaluation and docking studies of some new fluorinated fused quinazolines
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Author keywords
Anti inflammatory activity; Cyclooxygenase; Docking studies; Fluorinated quinazolines
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Indexed keywords
10 PHENYL 5 (THIOPHENE 2 YL) 8 (TRIFLUOROMETHYL) 2,3 DIHYDROIMIDAZO[1,2 C] QUINAZOLINE 7 CARBOXAMIDE;
2 (4 HYDROXYPHENYL) 4 OXO 5 PHENYL 7 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINAZOLINE 8 CARBOXAMIDE;
2 (4 HYDROXYPHENYL) 4 OXO 7 PHENYL 5 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINAZOLINE 8 CARBOXAMIDE;
2 (4 HYDROXYPHENYL) 4 OXO 7 PHENYL 5 (TRIFLUOROMETHYL) 3,4 DIHYDROQUINAZOLINE 8 CARBOXAMIDE;
2 (FURAN 2 YL) 4 OXO 5 PHENYL 7 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINAZOLINE 8 CARBOXAMIDE;
2 (FURAN 2 YL) 4 OXO 5 PHENYL 7 (TRIFLUOROMETHYL) 3,4 DIHYDROQUINAZOLINE 8 CARBOXAMIDE;
2 (FURAN 2 YL) 4 OXO 7 PHENYL 5 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINAZOLINE 8 CARBOXAMIDE;
2 (FURAN 2 YL) 4 OXO 7 PHENYL 5 (TRIFLUOROMETHYL) 3,4 DIHYDROQUINAZOLINE 8 CARBOXAMIDE;
2,6 DICARBOXAMIDO 3 TRIFLUOROMETHYL 5 PHENYL ANILINE;
2,6 DICYANO 3 TRIFLUOROMETHYL 5 PHENYL ANILINE;
3 CYANO 4 TRIFLUOROMETHYL 6 PHENYL 2 (1H) PYRIDONE;
4 [5 (4 BROMOPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE;
4 OXO 5 PHENYL 2 (THIOPHEN 2 YL) 7 (TRIFLUOROMETHYL) ,3,4 DIHYDROQUINAZOLINE 8 CARBOXAMIDE;
4 OXO 5 PHENYL 2 (THIOPHEN 2 YL) 7 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINAZOLINE 8 CARBOXAMIDE;
4 OXO 7 PHENYL 2 (THIOPHEN 2 YL) 5 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINAZOLINE 8 CARBOXAMIDE;
4 OXO 7 PHENYL 2 (THIOPHEN 2 YL) 5 (TRIFLUOROMETHYL) 3,4 DIHYDROQUINAZOLINE 8 CARBOXAMIDE;
4,4,4 TRIFLUORO 1 PHENYLBUTANE 1,3 DIONE;
5 (4 HYDROXYPHENYL) 10 PHENYL 8 (TRIFLUOROMETHYL) 2,3 DIHYDROIMIDAZO[1,2 C] QUINAZOLINE 7 CARBOXAMIDE;
5 (4 HYDROXYPHENYL) 8 PHENYL 10 (TRIFLUOROMETHYL) 2,3 DIHYDROIMIDAZO[1,2 C] QUINAZOLINE 7 CARBOXAMIDE;
5 (FURAN 2 YL) 10 PHENYL 8 (TRIFLUOROMETHYL) 2,3 DIHYDROIMIDAZO[1,2 C]QUINAZOLINE 7 CARBOXAMIDE;
5 (FURAN 2 YL) 8 PHENYL 10 (TRIFLUOROMETHYL) 2,3 DIHYDROIMIDAZO[1,2 C]QUINAZOLINE 7 CARBOXAMIDE;
6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE;
8 PHENYL 5 (THIOPHENE 2 YL) 10 (TRIFLUOROMETHYL) 2,3 DIHYDROIMIDAZO[1,2 C] QUINAZOLINE 7 CARBOXAMIDE;
ANTIINFLAMMATORY AGENT;
DICLOFENAC;
INDOMETACIN;
QUINAZOLINE DERIVATIVE;
ROFECOXIB;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
VALDECOXIB;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
COMPUTER PROGRAM;
CONTROLLED STUDY;
DRUG BINDING;
DRUG SCREENING;
DRUG SYNTHESIS;
FEMALE;
FLUORINATION;
IN VIVO STUDY;
MOLECULAR DOCKING;
NONHUMAN;
PAW EDEMA;
RAT;
ANIMALS;
ANTI-INFLAMMATORY AGENTS;
DRUG EVALUATION, PRECLINICAL;
FEMALE;
FLUORINE;
MAGNETIC RESONANCE SPECTROSCOPY;
MODELS, MOLECULAR;
QUINAZOLINES;
RATS;
RATS, WISTAR;
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EID: 77957825055
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2010.07.063 Document Type: Article |
Times cited : (187)
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References (30)
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