Aqueous boundary layers related to oral absorption of a drug: From dissolution of a drug to carrier mediated transport and intestinal wall metabolism

Molecular Pharmaceutics

Volumn 7, Issue 5, 2010, Pages 1362-1373

  Sugano, Kiyohiko ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

aqueous boundary layer; Dissolution; laminar; mass transfer; oral absorption; permeation; Reynolds number; Schmitt number; Sherwood number; turbulent; unstirred water layer

Indexed keywords

DRUG; DRUG CARRIER;

AQUEOUS BOUNDARY LAYER; CALCULATION; DRUG ABSORPTION; DRUG METABOLISM; DRUG SOLUBILITY; DRUG TRANSPORT; INTESTINE WALL; LAMINAR FLOW; MEMBRANE TRANSPORT; PERMEABILITY BARRIER; PRIORITY JOURNAL; REVIEW; THEORY; TURBULENT FLOW;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT, ACTIVE; CHEMISTRY, PHARMACEUTICAL; DRUG DISCOVERY; HUMANS; INTESTINAL ABSORPTION; INTESTINES; MODELS, BIOLOGICAL; SOLUBILITY; WATER;

EID: 77957726083     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp1001119     Document Type: Review

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