Characterization of flow and mixing regimes within the ileum of the brushtail possum using residence time distribution analysis with simultaneous spatio-temporal mapping

Journal of Physiology

Volumn 582, Issue 3, 2007, Pages 1239-1248

  Janssen, P W M ^a   Lentle, R G ^a   Asvarujanon, P ^a   Chambers, P ^b   Stafford, K J ^b   Hemar, Y ^a  

^a MASSEY UNIVERSITY   (New Zealand)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

DYE; GUAR GUM;

ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLOW KINETICS; ILEUM CONTRACTION; ILEUM MOTILITY; ILEUM MUCOSA; INTESTINE ABSORPTION; INTESTINE PERFUSION; INTESTINE TRANSIT TIME; LAMINAR FLOW; NONHUMAN; OSCILLATION; PERISTALSIS; PRIORITY JOURNAL; STEADY STATE; VISCOSITY; ABSORPTION; ANIMAL CELL; DIFFUSION; FEMALE; FLOW MEASUREMENT; ILEUM; MALE; MEDICAL PARAMETERS; MOLECULAR DYNAMICS; RESIDENCE TIME DISTRIBUTION; SPATIOTEMPORAL ANALYSIS; STIRRED REACTOR; TERMINAL ILEUM; VELOCITY;

ANIMALS; CALIBRATION; GALACTANS; GASTROINTESTINAL MOTILITY; ILEUM; KINETICS; MANNANS; MUSCLE, SMOOTH; OPOSSUMS; OSCILLOMETRY; PLANT GUMS; SOLUTIONS; TIME FACTORS;

EID: 34547107301     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.134403     Document Type: Article

References (29)

1. Amidon GL, Debrincat GA & Najib N (1991). Effects of gravity on gastric emptying, intestinal transit and drug absorption. J Clin Pharamacol 31, 968-973.
2. Arun CP (2004). The importance of being asymmetric: The physiology of digesta propulsion on earth and in space. Ann N Y Acad Sci 1027, 74-84.
3. Bayliss W & Starling EH (1899). Movements and innervation in the small intestine. J Physiol 24, 99-143.
4. Castelain C, Mokrani A, Legentilhomme P & Peerhossaini H (1997). Residence time distribution in twisted pipe flows: Helically coiled system and chaotic system. Exp Fluids 22, 359-368.
5. Christensen J (1960). Responses of smooth muscle to quick stretch; relation of stretch to conduction. Am J Physiol 198, 921-925.
6. Danckwerts PV (1953). Continuous flow systems; distribution of residence times. Chem Eng Sci 2, 1-13.
7. Davenport HW (1977). Physiology of the Digestive Tract: An Introductory Text, 4th edn. Year Book Medical Publishers, Chicago.
8. Dellow DW (1982). Studies on the nutrition of macropodine marsupials. III. The flow of digesta through the stomach and intestine of macropodines and sheep. Aust J Zoo 30, 391-398.
9. Forbes DK & Tribe DE (1970). The utilisation of roughages by sheep and kangaroos. Aust J Zoo 18, 247-256.
10. Hennig GW, Costa M, Chen BN & Brookes SJH (1999). Quantitative analysis of peristalsis in the guinea-pig small intestine using spatio-temporal maps. J Physiol 517, 575-590.
11. Hume ID (1999). Marsupial Nutrition. Cambridge University Press, Cambridge.
12. Jeffrey B, Udaykumar HS & Schultze KS (2003). Flow fields generated by peristaltic reflex in isolated guinea pig ileum: Impact of contraction depth and shoulders. Am J Physiol Gastrointest Liver Physiol 285, G907-G918.
13. Jumars PA (2000 a). Animal guts as ideal chemical reactors; maximising absorption rates. Am Nat 155, 527-543.
14. Jumars PA (2000 b). Animal guts as non-ideal chemical reactors; partial mixing and axial variation in absorption kinetics. Am Nat 155, 544-555.
15. Lammers WJEP, Lammers-van de Berg AM, Morrison JFB & Petroianu GA (2006). Translating Trendelenberg; back to the future. Naunyn-Schmiedebergs's Arch Pharmacol 373, 134-138.
16. Lentle RG, Hemar Y & Hall CE (2006). Viscoelastic behaviour aids extrusion from and reabsorption of the liquid phase into the digesta plug: Creep rheometry of hindgut digesta in the common brushtail possum Trichosurus vulpecula. J Comp Physiol B 176, 469-475.
17. Lentle RG, Hemar Y, Hall CE & Stafford KJ (2005). Periodic fluid extrusion and models of digesta mixing in the intestine of a herbivore, the common brushtail possum (Trichosurus vulpecula). J Comp Physiol B 175, 337-347.
18. Lentle RG, Janssen PWM, Asvarujanon P, Chambers P, Stafford KJ & Hemar Y (2007). High definition mapping of circular and longitudinal motility in the terminal ileum of the brushtail possum Trichosurus vulpecula with watery and viscous perfusates. J Comp Physiol B (in press, DOI:).
19. Lentle RG, Stafford KJ, Kennedy MS & Haslett SJ (2002). Rheological properties of digesta suggest little radial or axial mixing in the forestomach of the tammmar (Macropus eugenii) and the parma (Macropus parma) wallaby. Physiol Zoo 75, 572-582.
20. Levenspiel O (1999). Chemical Reaction Engineering, 3rd edn. John Wiley, New York.
21. Macagno EO & Christensen J (1980). Fluid mechanics in the duodenum. Ann Rev Fluid Mech 12, 139-158.
22. Macagno EO & Christensen J (1981). Fluid mechanics of gastrointestinal flow. In Physiology of the Gastrointestinal Tract, 1st edn, ed. Johnson LR, pp. 335-358. Raven Press, New York.
23. Melville J, Macagno EO & Christensen J (1975). Longitudinal contractions in the duodenum: Their fluid-mechanical function. Am J Physiol 228, 1887-1892.
24. Penry DL & Jumars PA (1987). Modelling animal guts as chemical reactors. Am Nat 129, 69-96.
25. Sakiadis BC (1984). Fluid and particle mechanics. In Perry's Chemical Engineers' Handbook, 5th edn, ed. Perry RH & Green DW. McGraw-Hill, New York.
26. Spencer N, Walsh M & Smith TK (1999). Does the guinea-pig ileum obey the 'law of the intestine'? J Physiol 517, 889-898.
27. Stevens RJ, Publicover NG & Smith TK (2000). Propagation and neural regulation of calcium waves in longitudinal and circular muscle layers of guinea pig small intestine. Gastroenterology 118, 892-904.
28. Trendelenburg P (1917). Physiologische und pharmakologische Versuche über die Dünndarm Peristaltick. Naunyn-Schmiedebergs Arch Exp Pathol Pharmakol 81, 55-129.
29. Weems WA (1982). Intestinal wall motion, propulsion, and fluid movement: trends toward a unified theory. Am J Physiol Gastrointest Liver Physiol 243, G177-G188.