Particle diffusional layer thickness in a USP dissolution apparatus II: A combined function of particle size and paddle speed

Journal of Pharmaceutical Sciences

Volumn 97, Issue 11, 2008, Pages 4815-4829

  Sheng, Jennifer J ^a,d   Sirois, Paul J ^b   Dressman, Jennifer B ^c   Amidon, Gordon L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c GOETHE UNIVERSITY   (Germany)

^d ASTRAZENECA   (United Kingdom)

Author keywords

Bioequivalence; Diffusion; Diffusional layer thickness; Dimensionless number; Dissolution; Fenofibrate; Fluid velocity; Gastrointestinal mathematical models; Hydrodynamics; In vitro models; Particle size; USP dissolution apparatus

Indexed keywords

FENOFIBRATE;

ARTICLE; DIFFUSION; DRUG SOLUBILITY; FLUID FLOW; HYDRODYNAMICS; MATHEMATICAL MODEL; PARTICLE SIZE; THICKNESS;

EID: 55749090038     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21345     Document Type: Article

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