Antiproliferative effects induced by guanine-based purines require hypoxanthine-guanine phosphoribosyltransferase activity

Biological Chemistry

Volumn 391, Issue 9, 2010, Pages 1079-1089

  Garozzo, Roberta ^a   Sortino, Maria Angela ^a   Vancheri, Carlo ^a   Condorelli, Daniele Filippo ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

growth inhibition; guanine; purine pool imbalance; purine salvage pathway; tumor

Indexed keywords

ADENINE; ADENOSINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CYTIDINE; CYTIDINE PHOSPHATE; CYTOSINE; DIPYRIDAMOLE; GUANINE; GUANINE DERIVATIVE; GUANOSINE; GUANOSINE PHOSPHATE; HYPOXANTHINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINE; NUCLEOSIDE; NUCLEOTIDE; PAPAVERINE; PHLORIZIN; PURINE DERIVATIVE; RNA; SMALL INTERFERING RNA; THYMINE; URACIL; URIDINE; URIDINE PHOSPHATE; XANTHINE;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; GLIOMA; GLIOMA CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PURINE METABOLISM; TUMOR CELL LINE;

CELL PROLIFERATION; COLORIMETRY; GUANINE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PURINES; TUMOR CELLS, CULTURED;

EID: 77957593413     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2010.106     Document Type: Article

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