Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms

Drug Development Research

Volumn 52, Issue 1-2, 2001, Pages 303-315

  Di Iorio, Patrizia ^a   Caciagli, Francesco ^a   Giuliani, Patricia ^a   Ballerini, Patrizia ^a   Ciccarelli, Renata ^a   Sperling, Oded ^b   Zoref Shani, Esther ^b   Benowitz, Larry ^c   Traversa, Ugo ^d   Bombi, Giulia ^d   Florio, Tulio ^a   Virgilio, Antonella ^a   Andrew, Craig M ^e   Crocker, Candice E ^e   Werstiuk, Eva S ^e   Middlemiss, Pamela J ^e   Rathbone, Michel P ^e  

^a UNIVERSITY OF CHIETI   (Italy)

^b TEL AVIV UNIVERSITY   (Israel)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF TRIESTE   (Italy)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Apoptosis; Astrocytes; GTP; Guanosine; Inosine; MAP kinase; Microglia; Mitogenesis; Nerve regeneration

Indexed keywords

ADENOSINE RECEPTOR; CALCIUM; FIBROBLAST GROWTH FACTOR; GUANINE; GUANINE DEAMINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; GUANOSINE TRIPHOSPHATE; INOSINE; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PROTEIN KINASE; PURINE NUCLEOSIDE; PURINE P2 RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; XANTHINE;

ANIMAL CELL; CALCIUM TRANSPORT; CATALYSIS; CELL DIFFERENTIATION; CELL GROWTH; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; MITOGENESIS; NERVE INJURY; NERVE REGENERATION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; RAT;

EID: 0035037701     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1128     Document Type: Conference Paper

References (3)

1. 3 receptor. Ann NY Acad Sci 825:11-19.
2. Aguayo AJ, Rasminsky M, Bray GM, Carbonetto S, McKerracher L, Villegas-Perez MP, Vidal-Sanz M, Carter DA. 1991. Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals. Philos Trans R Soc Lond B Biol 331:337-343.
3. Bastaki, M, Nelli, EE, Dell'Era, P, Rusnati, M, Molinari-Tosatti, MP, Parolini, S, Auerbach, R, Rucco, LP, Possati, L, Presta, M. 1997. Basic fibroblast growth factor-induced angiogenic phenotype in mouse endothelium: a study of aortic and microvascular endothelial cell lines. Thromb Vase Biol 17:454-464.