Unexpected acceleration of type 1 diabetes by transgenic expression of B7-H1 in NOD mouse peri-islet glia

Diabetes

Volumn 59, Issue 10, 2010, Pages 2588-2596

  Yantha, Jason ^a,b   Tsui, Hubert ^a,b   Winer, Shawn ^a,b   Song, Aihua ^a,b   Wu, Ping ^a,b   Paltser, Geoff ^a,b   Ellis, James ^c   Dosch, H Michael ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOPROTEIN P 15095; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; BINDING AFFINITY; CD8+ T LYMPHOCYTE; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GENE EXPRESSION; GENOTOXICITY; GLIA; IMMUNOREACTIVITY; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SCHWANN CELL; T LYMPHOCYTE ACTIVATION; TRANSGENE; WILD TYPE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD80; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION; GLIAL FIBRILLARY ACIDIC PROTEIN; HISTOCYTOCHEMISTRY; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; PEPTIDES; PROMOTER REGIONS, GENETIC; SURFACE PLASMON RESONANCE; T-LYMPHOCYTES;

EID: 77957580490     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1209     Document Type: Article

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