메뉴 건너뛰기




Volumn 99, Issue 10, 2010, Pages 4326-4336

Spinning disc processing technology: Potential for large-scale manufacture of chitosan nanoparticles

Author keywords

Biodegradable polymers; Chitosan; Freeze drying lyophilisation; Large scale manufacture; Light scattering (dynamic); Nanoparticles; Spinning disc processor; Stability

Indexed keywords

ACETYLCYSTEINE; CHITOSAN; NANOPARTICLE; PARACETAMOL; TRIPOLYPHOSPHATE;

EID: 77957373814     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22145     Document Type: Article
Times cited : (34)

References (51)
  • 2
    • 0027242541 scopus 로고
    • Biochemical significance of exogenous chitins and chitosans in animals and patients
    • Muzzarelli RAA. 1993. Biochemical significance of exogenous chitins and chitosans in animals and patients. Carbohydr Polym 20:7-16.
    • (1993) Carbohydr Polym , vol.20 , pp. 7-16
    • Muzzarelli, R.A.A.1
  • 3
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • DOI 10.1023/A:1011929016601
    • Illum L. 1998. Chitosan and its use as a pharmaceutical excipient. Pharm Res 15:1326-1331. (Pubitemid 28427917)
    • (1998) Pharmaceutical Research , vol.15 , Issue.9 , pp. 1326-1331
    • Illum, L.1
  • 4
    • 0030748702 scopus 로고    scopus 로고
    • Human enzymatic activities related to the therapeutic administration of chitin derivatives
    • Muzzarelli RAA. 1996. Human enzymatic activities related to the therapeutic administration of chitin derivatives. Cell Mol Life Sci 53:131-140.
    • (1996) Cell Mol Life Sci , vol.53 , pp. 131-140
    • Muzzarelli, R.A.A.1
  • 5
    • 77957347013 scopus 로고    scopus 로고
    • North Carolina, US: National Toxicology Program
    • Walker J. 1999. Chitosan. North Carolina, US: National Toxicology Program.
    • (1999) Chitosan
    • Walker, J.1
  • 6
    • 33846021271 scopus 로고    scopus 로고
    • In vitro and in vivo suppression of hepatocellular carcinoma growth by chitosan nanoparticles
    • Qi L, Xu Z, Chen M. 2007. In vitro and in vivo suppression of hepatocellular carcinoma growth by chitosan nanoparticles. Eur J Cancer 43:184-193.
    • (2007) Eur J Cancer , vol.43 , pp. 184-193
    • Qi, L.1    Xu, Z.2    Chen, M.3
  • 7
    • 3543046202 scopus 로고    scopus 로고
    • Chitosan nanoparticles as new ocular drug delivery systems: In vitro stability, in vivo fate, and cellular toxicity
    • de Campos AM, Diebold Y, Carvalho ELS, Sánchez A, Alonso MJ. 2004. Chitosan nanoparticles as new ocular drug delivery systems: In vitro stability, in vivo fate, and cellular toxicity. Pharm Res 21:803-810.
    • (2004) Pharm Res , vol.21 , pp. 803-810
    • De Campos, A.M.1    Diebold, Y.2    Carvalho, E.L.S.3    Sánchez, A.4    Alonso, M.J.5
  • 9
    • 0035997333 scopus 로고    scopus 로고
    • Nasal delivery of insulin using novel chitosan based formulations: A comparative study in two animal models between simple chitosan formulations and chitosan nanoparticles
    • DOI 10.1023/A:1016418523014
    • Dyer AM, M Hinchcliffe M, Watts P, Castile J, Jabbal-Gill I, Nankervis R, Smith A, Illum L. 2002. Nasal delivery of insulin using novel chitosan based formulations: A comparative study in two animal models between simple chitosan formulations and chitosan nanoparticles. Pharm Res 19:998-1008. (Pubitemid 34804242)
    • (2002) Pharmaceutical Research , vol.19 , Issue.7 , pp. 998-1008
    • Dyer, A.M.1    Hinchcliffe, M.2    Watts, P.3    Castile, J.4    Jabbal-Gill, I.5    Nankervis, R.6    Smith, A.7    Illum, L.8
  • 12
    • 0009127839 scopus 로고    scopus 로고
    • Process intensification: Spinning disc reactor for condensation polymerisation
    • Boodhoo KVK, Jachuck RJ. 2000. Process intensification: Spinning disc reactor for condensation polymerisation. Green Chem 2:235-244.
    • (2000) Green Chem , vol.2 , pp. 235-244
    • Boodhoo, K.V.K.1    Jachuck, R.J.2
  • 14
    • 25844492985 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan-based nanoparticles
    • Bodnar M, Hartmann JF, Borbely J. 2005. Preparation and characterization of chitosan-based nanoparticles. Biomacromolecules 6:2521-2527.
    • (2005) Biomacromolecules , vol.6 , pp. 2521-2527
    • Bodnar, M.1    Hartmann, J.F.2    Borbely, J.3
  • 16
    • 41549121442 scopus 로고    scopus 로고
    • Size selective synthesis of superparamagnetic nanoparticles in thin fluids under continuous flow conditions
    • DOI 10.1002/adfm.200701101
    • Chin SF, Iyer KS, Saunders M, Raston CL. 2008. Size selective synthesis of superparamagnetic nanoparticles in thin fluids under continuous flowconditions. Adv Funct Mater 18: 922-927. (Pubitemid 351473705)
    • (2008) Advanced Functional Materials , vol.18 , Issue.6 , pp. 922-927
    • Chin, S.F.1    Iyer, K.S.2    Raston, C.L.3    Saunders, M.4
  • 17
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and Cytotoxicity of Chitosan Molecules and Nanoparticles: Effects of Molecular Weight and Degree of Deacetylation
    • DOI 10.1023/B:PHAM.0000016249.52831.a5
    • Huang M, Khor E, Lim LY. 2004. Uptake and cytotoxicity of chitosan molecules and nanoparticles: Effects of molecular weight and degree of deacetylation. Pharm Res 21:344-353. (Pubitemid 38221982)
    • (2004) Pharmaceutical Research , vol.21 , Issue.2 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.-Y.3
  • 18
    • 2842576198 scopus 로고
    • Determination of the viscometric constants for chitosan
    • Roberts GAF, Domszy JG. 1982. Determination of the viscometric constants for chitosan. Int J Biol Macromol 4:374-377.
    • (1982) Int J Biol Macromol , vol.4 , pp. 374-377
    • Roberts, G.A.F.1    Domszy, J.G.2
  • 19
    • 0032006591 scopus 로고    scopus 로고
    • The degree of deacetylation of chitosan: Advocating the first derivative UV-spectrophotometry method of determination
    • DOI 10.1016/S0039-9140(97)00288-9, PII S0039914097002889
    • Tan SC, Khor E, Tan TK, Wong SM. 1998. The degree of deacetylation of chitosan: Advocating the first derivative UV-spectrophotometry method of determination. Talanta 45:713-719. (Pubitemid 28126509)
    • (1998) Talanta , vol.45 , Issue.4 , pp. 713-719
    • Tan, S.C.1    Khor, E.2    Tan, T.K.3    Wong, S.M.4
  • 21
    • 23444441931 scopus 로고    scopus 로고
    • Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery
    • DOI 10.1016/j.colsurfb.2005.06.001, PII S0927776505001682
    • Gan Q, Wang T, Cochrane C, McCarron P. 2005. Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery. Colloids Surf B Biointerfaces 44:65-73. (Pubitemid 41111534)
    • (2005) Colloids and Surfaces B: Biointerfaces , vol.44 , Issue.2-3 , pp. 65-73
    • Gan, Q.1    Wang, T.2    Cochrane, C.3    McCarron, P.4
  • 22
    • 38049088818 scopus 로고    scopus 로고
    • Thiolated chitosan nanoparticles: Transfection study in the Caco-2 differentiated cell culture
    • Martien R, Loretz B, Sandbichler AM, Schn̈urch AB. 2008. Thiolated chitosan nanoparticles: Transfection study in the Caco-2 differentiated cell culture. Nanotechnology 19:1-9.
    • (2008) Nanotechnology , vol.19 , pp. 1-9
    • Martien, R.1    Loretz, B.2    Sandbichler, A.M.3    Schn̈urch, A.B.4
  • 23
    • 18844447266 scopus 로고    scopus 로고
    • Oncostatin M induces an acute phase response but does not modulate the growth or maturationstatus of liver progenitor (oval) cells in culture
    • Matthews VB, Knight B, Tirnitz-Parker JEE, Boon J, Olynyk JK, Yeoh GCT. 2005. Oncostatin M induces an acute phase response but does not modulate the growth or maturationstatus of liver progenitor (oval) cells in culture. Exp Cell Res 306:252-263.
    • (2005) Exp Cell Res , vol.306 , pp. 252-263
    • Matthews, V.B.1    Knight, B.2    Tirnitz-Parker, J.E.E.3    Boon, J.4    Olynyk, J.K.5    Yeoh, G.C.T.6
  • 24
    • 34748910077 scopus 로고    scopus 로고
    • Isolation, culture and immortalisation of hepatic oval cells from adult mice fed a choline-deficient, ethionine-supplemented diet
    • Tirnitz-Parker JEE, Tonkin JN, Knight B, Olynyk JK, Yeoh GCT. 2007. Isolation, culture and immortalisation of hepatic oval cells from adult mice fed a choline-deficient, ethionine-supplemented diet. Int J Biochem Cell Biol 39:2226-2239.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 2226-2239
    • Tirnitz-Parker, J.E.E.1    Tonkin, J.N.2    Knight, B.3    Olynyk, J.K.4    Yeoh, G.C.T.5
  • 25
    • 57749182923 scopus 로고    scopus 로고
    • Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study
    • Ajun W, Yan S, Li G, Huili L. 2009. Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study. Carbohydr Polym 75:566-574.
    • (2009) Carbohydr Polym , vol.75 , pp. 566-574
    • Ajun, W.1    Yan, S.2    Li, G.3    Huili, L.4
  • 27
    • 0032952283 scopus 로고    scopus 로고
    • PLGA nanoparticles prepared by nanoprecipitation: Drug loading and release studies of a water soluble drug
    • Govender T, Stolnik S, Garnett MC, Illum L, Davis SS. 1999. PLGA nanoparticles prepared by nanoprecipitation: Drug loading and release studies of a water soluble drug. J Control Release 57:171-185.
    • (1999) J Control Release , vol.57 , pp. 171-185
    • Govender, T.1    Stolnik, S.2    Garnett, M.C.3    Illum, L.4    Davis, S.S.5
  • 28
    • 70849091247 scopus 로고    scopus 로고
    • Preparation of aminoglycoside-loaded chitosan nanoparticles using dextran sulphate as a counterion
    • Lu E, Franzblau S, Onyuksel H, Popescu C. 2009. Preparation of aminoglycoside-loaded chitosan nanoparticles using dextran sulphate as a counterion. J Microencapsul 26:346-354.
    • (2009) J Microencapsul , vol.26 , pp. 346-354
    • Lu, E.1    Franzblau, S.2    Onyuksel, H.3    Popescu, C.4
  • 29
    • 36348963072 scopus 로고    scopus 로고
    • Controlled scalable synthesis of ZnO nanoparticles
    • Hartlieb KJ, Raston CL, Saunders M. 2007. Controlled scalable synthesis of ZnO nanoparticles. Chem Mater 19:5453-5459.
    • (2007) Chem Mater , vol.19 , pp. 5453-5459
    • Hartlieb, K.J.1    Raston, C.L.2    Saunders, M.3
  • 30
    • 36448986411 scopus 로고    scopus 로고
    • Fabrication of laterally 'sliced' metal plated carbon nanotubes under aqueous continuous flow conditions
    • Iyer KS, Raston CL. 2007. Fabrication of laterally 'sliced' metal plated carbon nanotubes under aqueous continuous flow conditions. J Mater Chem 17:4872-4875.
    • (2007) J Mater Chem , vol.17 , pp. 4872-4875
    • Iyer, K.S.1    Raston, C.L.2
  • 31
    • 36348945124 scopus 로고    scopus 로고
    • Continuous flow nanotechnology: Manipulating the size, shape, agglomeration, defects and phases of silver nano-particles
    • Iyer KS, Raston CL, Saunders M. 2007. Continuous flow nanotechnology: Manipulating the size, shape, agglomeration, defects and phases of silver nano-particles. Lab Chip 7:1800-1805.
    • (2007) Lab Chip , vol.7 , pp. 1800-1805
    • Iyer, K.S.1    Raston, C.L.2    Saunders, M.3
  • 32
    • 0037190020 scopus 로고    scopus 로고
    • Preparation, characterisation and biodistribution of ultrafine chitosan nanoparticles
    • Banerjee T, Mitra S, Singh AK, Sharma RK, Maitra A. 2002. Preparation, characterisation and biodistribution of ultrafine chitosan nanoparticles. Int J Pharm 243:93-105.
    • (2002) Int J Pharm , vol.243 , pp. 93-105
    • Banerjee, T.1    Mitra, S.2    Singh, A.K.3    Sharma, R.K.4    Maitra, A.5
  • 33
    • 26244467518 scopus 로고    scopus 로고
    • In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells
    • Qi LF, Xu ZR, Li Y, Jiang X, Han XY. 2005. In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells. World J Gastroenterol 11:5136-5141.
    • (2005) World J Gastroenterol , vol.11 , pp. 5136-5141
    • Qi, L.F.1    Xu, Z.R.2    Li, Y.3    Jiang, X.4    Han, X.Y.5
  • 34
    • 7444268954 scopus 로고    scopus 로고
    • Recent advances on chitosan-based micro- and nanoparticles in drug delivery
    • Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. 2004. Recent advances on chitosan-based micro- and nanoparticles in drug delivery. J Control Release 100:5-28.
    • (2004) J Control Release , vol.100 , pp. 5-28
    • Agnihotri, S.A.1    Mallikarjuna, N.N.2    Aminabhavi, T.M.3
  • 36
    • 7044229930 scopus 로고    scopus 로고
    • Preparation and antibacterial activity of chitosan nanoparticles
    • Qi L, Xu Z, Jiang X, Hu C, Zou X. 2004. Preparation and antibacterial activity of chitosan nanoparticles. Carbohydr Res 339:2693-2700.
    • (2004) Carbohydr Res , vol.339 , pp. 2693-2700
    • Qi, L.1    Xu, Z.2    Jiang, X.3    Hu, C.4    Zou, X.5
  • 37
    • 0032947396 scopus 로고    scopus 로고
    • Effects of dry heat and saturated steam on the physical properties of Chitosan
    • Lim LY, Khor E, Ling C. 1999. Effects of dry heat and saturated steam on the physical properties of Chitosan. J Biomed Mater Res 48:111-116.
    • (1999) J Biomed Mater Res , vol.48 , pp. 111-116
    • Lim, L.Y.1    Khor, E.2    Ling, C.3
  • 38
    • 0032580495 scopus 로고    scopus 로고
    • DNA-polycation nanospheres as non-viral gene delivery vehicles
    • Leong KW, Mao HQ, Truong-Le VL. 1998. DNA-polycation nanospheres as non-viral gene delivery vehicles. J Control Release 53:183-193.
    • (1998) J Control Release , vol.53 , pp. 183-193
    • Leong, K.W.1    Mao, H.Q.2    Truong-Le, V.L.3
  • 39
    • 0035117746 scopus 로고    scopus 로고
    • Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation
    • Shu XZ, Zhu KJ. 2001. Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation. J Microencapsul 18:237.
    • (2001) J Microencapsul , vol.18 , pp. 237
    • Shu, X.Z.1    Zhu, K.J.2
  • 40
    • 0031550212 scopus 로고    scopus 로고
    • Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers
    • Calvo P, Remuñán-López C, Vila-Jato JL, Alonso MJ. 1997. Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers. J Appl Polym Sci 63:125-132.
    • (1997) J Appl Polym Sci , vol.63 , pp. 125-132
    • Calvo, P.1    Remuñán-López, C.2    Vila-Jato, J.L.3    Alonso, M.J.4
  • 41
    • 9644269211 scopus 로고    scopus 로고
    • Lead sorption from aqueous solutions on chitosan nanoparticles
    • Qi L, Xu Z. 2004. Lead sorption from aqueous solutions on chitosan nanoparticles. Colloids Surf A Physicochem Eng Aspects 251:183-190.
    • (2004) Colloids Surf a Physicochem Eng Aspects , vol.251 , pp. 183-190
    • Qi, L.1    Xu, Z.2
  • 43
    • 0032661368 scopus 로고    scopus 로고
    • Chitosan-polyelectrolyte complexation for the preparation of gel beads and controlled release of anticancer drug. II. Effect of pH-dependent ionic crosslinking or interpolymer complex using tripolyphosphate or polyphosphate as reagent
    • Mi FL, Shyu SS, Wong TB, Jang SF, Lee ST, Lu KT. 1999. Chitosan-polyelectrolyte complexation for the preparation of gel beads and controlled release of anticancer drug. II. Effect of pH-dependent ionic crosslinking or interpolymer complex using tripolyphosphate or polyphosphate as reagent. J Appl Polym Sci 74:1093-1107.
    • (1999) J Appl Polym Sci , vol.74 , pp. 1093-1107
    • Mi, F.L.1    Shyu, S.S.2    Wong, T.B.3    Jang, S.F.4    Lee, S.T.5    Lu, K.T.6
  • 45
    • 0036692366 scopus 로고    scopus 로고
    • Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: The effect of mucus on particle adsorption and transport
    • Behrens I, Pena AIV, Alonso MJ, Kissel T. 2002. Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: The effect of mucus on particle adsorption and transport. Pharm Res 19:1185-1193.
    • (2002) Pharm Res , vol.19 , pp. 1185-1193
    • Behrens, I.1    Pena, A.I.V.2    Alonso, M.J.3    Kissel, T.4
  • 46
    • 34548324792 scopus 로고    scopus 로고
    • In vitro cytotoxicty testing of non-thiolated and thiolated chitosan nanoparticles for oral gene delivery
    • Loretz B, Bernkop-Schnurch A. 2007. In vitro cytotoxicty testing of non-thiolated and thiolated chitosan nanoparticles for oral gene delivery. Nanotoxicology 1:139-148.
    • (2007) Nanotoxicology , vol.1 , pp. 139-148
    • Loretz, B.1    Bernkop-Schnurch, A.2
  • 47
    • 0037148679 scopus 로고    scopus 로고
    • Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles
    • Konan YN, Gurny R, Allemann E. 2002. Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles. Int J Pharm 233:239-252.
    • (2002) Int J Pharm , vol.233 , pp. 239-252
    • Konan, Y.N.1    Gurny, R.2    Allemann, E.3
  • 49
    • 28444488033 scopus 로고    scopus 로고
    • Self-assembled nanoparticles based on linoleic-acid modified chitosan: Stability and adsorption of trypsin
    • Liu C-G, Chen X-G, Park H-J. 2005. Self-assembled nanoparticles based on linoleic-acid modified chitosan: Stability and adsorption of trypsin. Carbohydr Polym 62:293-298.
    • (2005) Carbohydr Polym , vol.62 , pp. 293-298
    • Liu, C.-G.1    Chen, X.-G.2    Park, H.-J.3
  • 50
    • 19944403927 scopus 로고    scopus 로고
    • Preparation and characterisation of drug-loaded chitosan-tripolyphosphate microspheres by spray drying
    • Desai KGH, Park HJ. 2005. Preparation and characterisation of drug-loaded chitosan-tripolyphosphate microspheres by spray drying. Drug Dev Res 64:114-128.
    • (2005) Drug Dev Res , vol.64 , pp. 114-128
    • Desai, K.G.H.1    Park, H.J.2
  • 51
    • 18744380086 scopus 로고    scopus 로고
    • Acetaminophen particle design using chitosan and a spray-drying technique
    • Takahashi H, Chen R, Okamoto H, Danjo K. 2005. Acetaminophen particle design using chitosan and a spray-drying technique. Chem Pharm Bull 53:37.
    • (2005) Chem Pharm Bull , vol.53 , pp. 37
    • Takahashi, H.1    Chen, R.2    Okamoto, H.3    Danjo, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.