-
1
-
-
0037167852
-
Detecting recent positive selection in the human genome from haplotype structure
-
DOI 10.1038/nature01140
-
Sabeti PC, Reich DE, Higgins JM, et al. Detecting recent positive selection in the human genome from haplotype structure. Nature 2002; 419:832-837. (Pubitemid 35238568)
-
(2002)
Nature
, vol.419
, Issue.6909
, pp. 832-837
-
-
Sabeti, P.C.1
Reich, D.E.2
Higgins, J.M.3
Levine, H.Z.P.4
Richter, D.J.5
Schaffner, S.F.6
Gabriel, S.B.7
Platko, J.V.8
Patterson, N.J.9
McDonald, G.J.10
Ackerman, H.C.11
Campbell, S.J.12
Altshuler, D.13
Cooper, R.14
Kwiatkowski, D.15
Ward, R.16
Lander, E.S.17
-
2
-
-
33745121154
-
Positive natural selection in the human lineage
-
DOI 10.1126/science.1124309
-
Sabeti PC, Schaffner SF, Fry B, et al. Positive natural selection in the human lineage. Science 2006; 312:1614-1620. (Pubitemid 43902654)
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1614-1620
-
-
Sabeti, P.C.1
Schaffner, S.F.2
Fry, B.3
Lohmueller, J.4
Varilly, P.5
Shamovsky, O.6
Palma, A.7
Mikkelsen, T.S.8
Altshuler, D.9
Lander, E.S.10
-
3
-
-
33746237567
-
Genomic insights into positive selection
-
DOI 10.1016/j.tig.2006.06.005, PII S0168952506001739
-
Biswas S, Akey JM. Genomic insights into positive selection. Trends Genet 2006; 22:437-446. (Pubitemid 44093769)
-
(2006)
Trends in Genetics
, vol.22
, Issue.8
, pp. 437-446
-
-
Biswas, S.1
Akey, J.M.2
-
4
-
-
35748983523
-
Approaches for identifying targets of positive selection
-
DOI 10.1016/j.tig.2007.08.009, PII S0168952507002971
-
Jensen JD, Wong A, Aquadro CF. Approaches for identifying targets of positive selection. Trends Genet 2007; 23:568-577. (Pubitemid 350052348)
-
(2007)
Trends in Genetics
, vol.23
, Issue.11
, pp. 568-577
-
-
Jensen, J.D.1
Wong, A.2
Aquadro, C.F.3
-
5
-
-
2442677652
-
Genetic signatures of strong recent positive selection at the lactase gene
-
DOI 10.1086/421051
-
Bersaglieri T, Sabeti PC, Patterson N, et al. Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet 2004; 74:1111-1120. (Pubitemid 38669310)
-
(2004)
American Journal of Human Genetics
, vol.74
, Issue.6
, pp. 1111-1120
-
-
Bersaglieri, T.1
Sabeti, P.C.2
Patterson, N.3
Vanderploeg, T.4
Schaffner, S.F.5
Drake, J.A.6
Rhodes, M.7
Reich, D.E.8
Hirschhorn, J.N.9
-
6
-
-
49749134703
-
The challenges for molecular nutrition research 1: Linking genotype to healthy nutrition
-
Williams CM, Ordovas JM, Lairon D, et al. The challenges for molecular nutrition research 1: linking genotype to healthy nutrition. Genes Nutr 2008; 3:41-49.
-
(2008)
Genes Nutr
, vol.3
, pp. 41-49
-
-
Williams, C.M.1
Ordovas, J.M.2
Lairon, D.3
-
7
-
-
34247851021
-
The epidemiology of obesity
-
DOI 10.1053/j.gastro.2007.03.052, PII S0016508507005793
-
Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. The epidemiology of obesity. Gastroenterology 2007; 132:2087-2102. (Pubitemid 46693751)
-
(2007)
Gastroenterology
, vol.132
, Issue.6
, pp. 2087-2102
-
-
Ogden, C.L.1
Yanovski, S.Z.2
Carroll, M.D.3
Flegal, K.M.4
-
8
-
-
60549102722
-
Gene-environment interaction and obesity
-
Qi L, Cho YA. Gene-environment interaction and obesity. Nutr Rev 2008; 66:684-694.
-
(2008)
Nutr Rev
, vol.66
, pp. 684-694
-
-
Qi, L.1
Cho, Y.A.2
-
9
-
-
23844479290
-
Genetics of common forms of obesity: A brief overview
-
Lyon HN, Hirschhorn JN. Genetics of common forms of obesity: a brief overview. Am J Clin Nutr 2005; 82:215S-217S.
-
(2005)
Am J Clin Nutr
, vol.82
-
-
Lyon, H.N.1
Hirschhorn, J.N.2
-
10
-
-
70349566593
-
Diabetes mellitus: A 'thrifty' genotype rendered detrimental by 'progress'?
-
Neel JV. Diabetes mellitus: a 'thrifty' genotype rendered detrimental by 'progress'? Am J Hum Genet 1962; 14:353-362.
-
(1962)
Am J Hum Genet
, vol.14
, pp. 353-362
-
-
Neel, J.V.1
-
11
-
-
35348988170
-
Recent and ongoing selection in the human genome
-
DOI 10.1038/nrg2187, PII NRG2187
-
Nielsen R, Hellmann I, Hubisz M, et al. Recent and ongoing selection in the human genome. Nat Rev Genet 2007; 8:857-868. (Pubitemid 47609088)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.11
, pp. 857-868
-
-
Nielsen, R.1
Hellmann, I.2
Hubisz, M.3
Bustamante, C.4
Clark, A.G.5
-
13
-
-
67349176068
-
Genetics in geographically structured populations: Defining, estimating and interpreting FST
-
Holsinger KE, Weir BS. Genetics in geographically structured populations: defining, estimating and interpreting FST. Nat Rev Genet 2009; 10:639-650.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 639-650
-
-
Holsinger, K.E.1
Weir, B.S.2
-
14
-
-
35349012592
-
Genome-wide detection and characterization of positive selection in human populations
-
DOI 10.1038/nature06250, PII NATURE06250
-
Sabeti PC, Varilly P, Fry B, et al. Genome-wide detection and characterization of positive selection in human populations. Nature 2007; 449:913-918. (Pubitemid 47598625)
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 913-918
-
-
Sabeti, P.C.1
Varilly, P.2
Fry, B.3
Lohmueller, J.4
Hostetter, E.5
Cotsapas, C.6
Xie, X.7
Byrne, E.H.8
McCarroll, S.A.9
Gaudet, R.10
Schaffner, S.F.11
Lander, E.S.12
Frazer, K.A.13
Ballinger, D.G.14
Cox, D.R.15
Hinds, D.A.16
Stuve, L.L.17
Gibbs, R.A.18
Belmont, J.W.19
Boudreau, A.20
Hardenbol, P.21
Leal, S.M.22
Pasternak, S.23
Wheeler, D.A.24
Willis, T.D.25
Yu, F.26
Yang, H.27
Zeng, C.28
Gao, Y.29
Hu, H.30
Hu, W.31
Li, C.32
Lin, W.33
Liu, S.34
Pan, H.35
Tang, X.36
Wang, J.37
Wang, W.38
Yu, J.39
Zhang, B.40
Zhang, Q.41
Zhao, H.42
Zhao, H.43
Zhou, J.44
Gabriel, S.B.45
Barry, R.46
Blumenstiel, B.47
Camargo, A.48
Defelice, M.49
Faggart, M.50
Goyette, M.51
Gupta, S.52
Moore, J.53
Nguyen, H.54
Onofrio, R.C.55
Parkin, M.56
Roy, J.57
Stahl, E.58
Winchester, E.59
Ziaugra, L.60
Altshuler, D.61
Shen, Y.62
Yao, Z.63
Huang, W.64
Chu, X.65
He, Y.66
Jin, L.67
Liu, Y.68
Shen, Y.69
Sun, W.70
Wang, H.71
Wang, Y.72
Wang, Y.73
Xiong, X.74
Xu, L.75
Waye, M.M.Y.76
Tsui, S.K.W.77
Xue, H.78
Wong, J.T.-F.79
Galver, L.M.80
Fan, J.-B.81
Gunderson, K.82
Murray, S.S.83
Oliphant, A.R.84
Chee, M.S.85
Montpetit, A.86
more..
-
15
-
-
38749149611
-
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: Serum urate and dyslipidemia
-
DOI 10.1016/j.ajhg.2007.11.001, PII S0002929707000262
-
Wallace C, Newhouse SJ, Braund P, et al. Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet 2008; 82:139-149. (Pubitemid 351735954)
-
(2008)
American Journal of Human Genetics
, vol.82
, Issue.1
, pp. 139-149
-
-
Wallace, C.1
Newhouse, S.J.2
Braund, P.3
Zhang, F.4
Tobin, M.5
Falchi, M.6
Ahmadi, K.7
Dobson, R.J.8
Marcano, A.C.B.9
Hajat, C.10
Burton, P.11
Deloukas, P.12
Brown, M.13
Connell, J.M.14
Dominiczak, A.15
Lathrop, G.M.16
Webster, J.17
Farrall, M.18
Spector, T.19
Samani, N.J.20
Caulfield, M.J.21
Munroe, P.B.22
more..
-
16
-
-
58149161560
-
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
-
Aulchenko YS, Ripatti S, Lindqvist I, et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2009; 41:47-55.
-
(2009)
Nat Genet
, vol.41
, pp. 47-55
-
-
Aulchenko, Y.S.1
Ripatti, S.2
Lindqvist, I.3
-
17
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
DOI 10.1038/ng.76, PII NG76
-
Willer CJ, Sanna S, Jackson AU, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008; 40:161-169. (Pubitemid 351171403)
-
(2008)
Nature Genetics
, vol.40
, Issue.2
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
Heath, S.C.7
Timpson, N.J.8
Najjar, S.S.9
Stringham, H.M.10
Strait, J.11
Duren, W.L.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Albai, G.16
Swift, A.J.17
Morken, M.A.18
Narisu, N.19
Bennett, D.20
Parish, S.21
Shen, H.22
Galan, P.23
Meneton, P.24
Hercberg, S.25
Zelenika, D.26
Chen, W.-M.27
Li, Y.28
Scott, L.J.29
Scheet, P.A.30
Sundvall, J.31
Watanabe, R.M.32
Nagaraja, R.33
Ebrahim, S.34
Lawlor, D.A.35
Ben-Shlomo, Y.36
Davey-Smith, G.37
Shuldiner, A.R.38
Collins, R.39
Bergman, R.N.40
Uda, M.41
Tuomilehto, J.42
Cao, A.43
Collins, F.S.44
Lakatta, E.45
Lathrop, G.M.46
Boehnke, M.47
Schlessinger, D.48
Mohlke, K.L.49
Abecasis, G.R.50
more..
-
18
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
DOI 10.1038/ng.75, PII NG75
-
Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008; 40:189-197. (Pubitemid 351171402)
-
(2008)
Nature Genetics
, vol.40
, Issue.2
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, M.J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
Wahlstrand, B.11
Hedner, T.12
Corella, D.13
Tai, E.S.14
Ordovas, J.M.15
Berglund, G.16
Vartiainen, E.17
Jousilahti, P.18
Hedblad, B.19
Taskinen, M.-R.20
Newton-Cheh, C.21
Salomaa, V.22
Peltonen, L.23
Groop, L.24
Altshuler, D.M.25
Orho-Melander, M.26
more..
-
19
-
-
38849166666
-
LDL-cholesterol concentrations: A genome-wide association study
-
DOI 10.1016/S0140-6736(08)60208-1, PII S0140673608602081
-
Sandhu MS, Waterworth DM, Debenham SL, et al. LDL-cholesterol concentrations: a genome-wide association study. Lancet 2008; 371:483-491. (Pubitemid 351199866)
-
(2008)
The Lancet
, vol.371
, Issue.9611
, pp. 483-491
-
-
Sandhu, M.S.1
Waterworth, D.M.2
Debenham, S.L.3
Wheeler, E.4
Papadakis, K.5
Zhao, J.H.6
Song, K.7
Yuan, X.8
Johnson, T.9
Ashford, S.10
Inouye, M.11
Luben, R.12
Sims, M.13
Hadley, D.14
McArdle, W.15
Barter, P.16
Kesaniemi, Y.A.17
Mahley, R.W.18
McPherson, R.19
Grundy, S.M.20
Bingham, S.A.21
Khaw, K.-T.22
Loos, R.J.23
Waeber, G.24
Barroso, I.25
Strachan, D.P.26
Deloukas, P.27
Vollenweider, P.28
Wareham, N.J.29
Mooser, V.30
more..
-
20
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009; 41:56-65.
-
(2009)
Nat Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
-
21
-
-
58149159573
-
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
-
Sabatti C, Service SK, Hartikainen AL, et al. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet 2009; 41:35-46.
-
(2009)
Nat Genet
, vol.41
, pp. 35-46
-
-
Sabatti, C.1
Service, S.K.2
Hartikainen, A.L.3
-
22
-
-
40049107734
-
Molecular population genetics of PCSK9: A signature of recent positive selection
-
DOI 10.1097/FPC.0b013e3282f44d99, PII 0121301120080300000001
-
Ding K, Kullo IJ. Molecular population genetics of PCSK9: a signature of recent positive selection. Pharmacogenet Genomics 2008; 18:169-179. (Pubitemid 351323231)
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, Issue.3
, pp. 169-179
-
-
Ding, K.1
Kullo, I.J.2
-
23
-
-
55449105227
-
Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13
-
Burkhardt R, Kenny EE, Lowe JK, et al. Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. Arterioscler Thromb Vasc Biol 2008; 28:2078-2084.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 2078-2084
-
-
Burkhardt, R.1
Kenny, E.E.2
Lowe, J.K.3
-
24
-
-
72149100752
-
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip
-
Talmud PJ, Drenos F, Shah S, et al. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Am J Hum Genet 2009; 85:628-642.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 628-642
-
-
Talmud, P.J.1
Drenos, F.2
Shah, S.3
-
25
-
-
44349152442
-
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol
-
DOI 10.1093/hmg/ddn060
-
Love-Gregory L, Sherva R, Sun L, et al. Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet 2008; 17:1695-1704. (Pubitemid 351737173)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.11
, pp. 1695-1704
-
-
Love-Gregory, L.1
Sherva, R.2
Sun, L.3
Wasson, J.4
Schappe, T.5
Doria, A.6
Rao, D.C.7
Hunt, S.C.8
Klein, S.9
Neuman, R.J.10
Permutt, M.A.11
Abumrad, N.A.12
-
26
-
-
46049116627
-
Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men
-
Madden J, Carrero JJ, Brunner A, et al. Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men. Prostaglandins Leukot Essent Fatty Acids 2008; 78:327-335.
-
(2008)
Prostaglandins Leukot Essent Fatty Acids
, vol.78
, pp. 327-335
-
-
Madden, J.1
Carrero, J.J.2
Brunner, A.3
-
27
-
-
48349120779
-
WW-domain-containing oxidor-eductase is associated with low plasma HDL-C levels
-
Lee JC, Weissglas-Volkov D, Kyttala M, et al. WW-domain-containing oxidor-eductase is associated with low plasma HDL-C levels. Am J Hum Genet 2008; 83:180-192.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 180-192
-
-
Lee, J.C.1
Weissglas-Volkov, D.2
Kyttala, M.3
-
28
-
-
38649084407
-
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
-
DOI 10.1038/ng.2007.61, PII NG200761
-
Kooner JS, Chambers JC, Aguilar-Salinas CA, et al. Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet 2008; 40:149-151. (Pubitemid 351171393)
-
(2008)
Nature Genetics
, vol.40
, Issue.2
, pp. 149-151
-
-
Kooner, J.S.1
Chambers, J.C.2
Aguilar-Salinas, C.A.3
Hinds, D.A.4
Hyde, C.L.5
Warnes, G.R.6
Gomez Perez, F.J.7
Frazer, K.A.8
Elliott, P.9
Scott, J.10
Milos, P.M.11
Cox, D.R.12
Thompson, J.F.13
-
29
-
-
58149262866
-
A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection
-
Pollin TI, Damcott CM, Shen H, et al. A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. Science 2008; 322:1702-1705.
-
(2008)
Science
, vol.322
, pp. 1702-1705
-
-
Pollin, T.I.1
Damcott, C.M.2
Shen, H.3
-
30
-
-
69249245293
-
The-1131T>CSNPof the APOA5gene modulates response to fenofibrate treatment in patients with the metabolic syndrome: A postprandial study
-
Cardona F, Guardiola M, Queipo-Ortuño MI, et al. The-1131T>CSNPof the APOA5gene modulates response to fenofibrate treatment in patients with the metabolic syndrome: a postprandial study. Atherosclerosis 2009; 206:148-152.
-
(2009)
Atherosclerosis
, vol.206
, pp. 148-152
-
-
Cardona, F.1
Guardiola, M.2
Queipo-Ortuño, M.I.3
-
31
-
-
72249110443
-
Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults
-
Mattei J, Demissie S, Tucker KL, Ordovas JM. Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults. J Nutr 2009; 139:2301-2308.
-
(2009)
J Nutr
, vol.139
, pp. 2301-2308
-
-
Mattei, J.1
Demissie, S.2
Tucker, K.L.3
Ordovas, J.M.4
-
32
-
-
66049157487
-
Signals of recent positive selection in a worldwide sample of human populations
-
Pickrell JK, Coop G, Novembre J, et al. Signals of recent positive selection in a worldwide sample of human populations. Genome Res 2009; 19:826-837.
-
(2009)
Genome Res
, vol.19
, pp. 826-837
-
-
Pickrell, J.K.1
Coop, G.2
Novembre, J.3
-
33
-
-
63749127623
-
Worldwide population differentiation at disease-associated SNPs
-
Myles S, Davison D, Barrett J, et al. Worldwide population differentiation at disease-associated SNPs. BMC Med Genomics 2008; 1:22.
-
(2008)
BMC Med Genomics
, vol.1
, pp. 22
-
-
Myles, S.1
Davison, D.2
Barrett, J.3
-
34
-
-
4644367204
-
Positive selection on MMP3 regulation has shaped heart disease risk
-
DOI 10.1016/j.cub.2004.08.051, PII S0960982204006153
-
Rockman MV, Hahn MW, Soranzo N, et al. Positive selection on MMP3 regulation has shaped heart disease risk. Curr Biol 2004; 14:1531-1539. (Pubitemid 39290050)
-
(2004)
Current Biology
, vol.14
, Issue.17
, pp. 1531-1539
-
-
Rockman, M.V.1
Hahn, M.W.2
Soranzo, N.3
Loisel, D.A.4
Goldstein, D.B.5
Wray, G.A.6
-
35
-
-
67149099343
-
Haplotype analysis of the stromelysin-1 (MMP3) and gelatinase B (MMP9) genes in relation to coronary heart disease
-
Wu N, Lu X, Hua Y, et al. Haplotype analysis of the stromelysin-1 (MMP3) and gelatinase B (MMP9) genes in relation to coronary heart disease. Ann Hum Genet 2009; 73 (Pt 4):404-410.
-
(2009)
Ann Hum Genet
, vol.73
, Issue.PART 4
, pp. 404-410
-
-
Wu, N.1
Lu, X.2
Hua, Y.3
-
36
-
-
66649106445
-
Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: The HyperGEN Study
-
Arnett DK, Li N, Tang W, et al. Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study. BMC Med Genet 2009; 10:43.
-
(2009)
BMC Med Genet
, vol.10
, pp. 43
-
-
Arnett, D.K.1
Li, N.2
Tang, W.3
-
37
-
-
67650103453
-
Genetic variants associated with cardiac structure and function: A meta-analysis and replication of genome-wide association data
-
Vasan RS, Glazer NL, Felix JF, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA 2009; 302:168-178.
-
(2009)
JAMA
, vol.302
, pp. 168-178
-
-
Vasan, R.S.1
Glazer, N.L.2
Felix, J.F.3
-
38
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy numbervariants
-
Myocardial Infarction Genetics Consortium
-
Myocardial Infarction Genetics Consortium, Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy numbervariants. Nat Genet 2009; 41:334-341.
-
(2009)
Nat Genet
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
Voight, B.F.2
Purcell, S.3
-
40
-
-
33847075832
-
A novel loss of function mutation of PCSK9 gene in white subjects with low-plasma low-density lipoprotein cholesterol
-
Fasano T, Cefalu AB, Di Leo E, et al. A novel loss of function mutation of PCSK9 gene in white subjects with low-plasma low-density lipoprotein cholesterol. Arterioscler Thromb Vasc Biol 2007; 27:677-681.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 677-681
-
-
Fasano, T.1
Cefalu, A.B.2
Di Leo, E.3
-
41
-
-
60549084697
-
Evolutionary genetics of coronary heart disease
-
Ding K, Kullo IJ. Evolutionary genetics of coronary heart disease. Circulation 2009; 119:459-467.
-
(2009)
Circulation
, vol.119
, pp. 459-467
-
-
Ding, K.1
Kullo, I.J.2
-
42
-
-
73149104856
-
Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men
-
Delgado-Lista J, Perez-Jimenez F, Ruano J, et al. Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men. J Lipid Res 2010; 51:63-73.
-
(2010)
J Lipid Res
, vol.51
, pp. 63-73
-
-
Delgado-Lista, J.1
Perez-Jimenez, F.2
Ruano, J.3
-
43
-
-
52949105366
-
Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease
-
Shanker J, Perumal G, Rao VS, et al. Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease. Lipids Health Dis 2008; 7:33.
-
(2008)
Lipids Health Dis
, vol.7
, pp. 33
-
-
Shanker, J.1
Perumal, G.2
Rao, V.S.3
-
44
-
-
60649103338
-
The apolipoprotein A5-1131T>C promoter polymorphism in Koreans: Association with plasma APOA5 and serum triglyceride concentrations, LDL particle size and coronary artery disease
-
Jang Y, Paik JK, Hyun YJ, et al. The apolipoprotein A5-1131T>C promoter polymorphism in Koreans: association with plasma APOA5 and serum triglyceride concentrations, LDL particle size and coronary artery disease. Clin Chim Acta 2009; 402:83-87.
-
(2009)
Clin Chim Acta
, vol.402
, pp. 83-87
-
-
Jang, Y.1
Paik, J.K.2
Hyun, Y.J.3
-
45
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
DOI 10.1126/science.1142842
-
Helgadottir A, Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007; 316:1491-1493. (Pubitemid 46906618)
-
(2007)
Science
, vol.316
, Issue.5830
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
Gretarsdottir, S.4
Blondal, T.5
Jonasdottir, A.6
Jonasdottir, A.7
Sigurdsson, A.8
Baker, A.9
Palsson, A.10
Masson, G.11
Gudbjartsson, D.F.12
Magnusson, K.P.13
Andersen, K.14
Levey, A.I.15
Backman, V.M.16
Matthiasdottir, S.17
Jonsdottir, T.18
Palsson, S.19
Einarsdottir, H.20
Gunnarsdottir, S.21
Gylfason, A.22
Vaccarino, V.23
Hooper, W.C.24
Reilly, M.P.25
Granger, C.B.26
Austin, H.27
Rader, D.J.28
Shah, S.H.29
Quyyumi, A.A.30
Gulcher, J.R.31
Thorgeirsson, G.32
Thorsteinsdottir, U.33
Kong, A.34
Stefansson, K.35
more..
-
46
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF, et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009; 41:18-24.
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
-
47
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Willer CJ, Speliotes EK, Loos RJ, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41:25-34.
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
-
48
-
-
64549158008
-
Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden
-
Renstrom F, Payne F, Nordstrom A, et al. Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. Hum Mol Genet 2009; 18:1489-1496.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1489-1496
-
-
Renstrom, F.1
Payne, F.2
Nordstrom, A.3
-
49
-
-
68449102930
-
Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes-and obesity-susceptibility variants?
-
Southam L, Soranzo N, Montgomery SB, et al. Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes-and obesity-susceptibility variants? Diabetologia 2009; 52:1846-1851.
-
(2009)
Diabetologia
, vol.52
, pp. 1846-1851
-
-
Southam, L.1
Soranzo, N.2
Montgomery, S.B.3
-
50
-
-
70349783304
-
Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference
-
Bauer F, Elbers CC, Adan RA, et al. Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference. Am J Clin Nutr 2009; 90:951-959.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 951-959
-
-
Bauer, F.1
Elbers, C.C.2
Adan, R.A.3
-
51
-
-
77950188611
-
Linkage and genome-wide association analysis of obesity-related phenotypes: Association of weight with the MGAT1 gene
-
[Epub ahead of print] doi:10.1038/oby.2009.359
-
Johansson A, Marroni F, Hayward C, et al. Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. Obesity (Silver Spring) 2009 [Epub ahead of print] doi:10.1038/oby.2009.359.
-
(2009)
Obesity (Silver Spring)
-
-
Johansson, A.1
Marroni, F.2
Hayward, C.3
-
52
-
-
65249183813
-
LIPE C-60G influences the effects of physical activity on body fat and plasma lipid concentrations: The Quebec Family Study
-
Garenc C, Vohl MC, Bouchard C, Perusse L. LIPE C-60G influences the effects of physical activity on body fat and plasma lipid concentrations: the Quebec Family Study. Hum Genomics 2009; 3:157-168.
-
(2009)
Hum Genomics
, vol.3
, pp. 157-168
-
-
Garenc, C.1
Vohl, M.C.2
Bouchard, C.3
Perusse, L.4
-
53
-
-
60849123166
-
WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake
-
Lai CQ, Parnell LD, Arnett DK, et al. WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake. Obesity (Silver Spring) 2009; 17:593-600.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 593-600
-
-
Lai, C.Q.1
Parnell, L.D.2
Arnett, D.K.3
-
54
-
-
70449650464
-
APOA2, dietary fat, and body mass index: Replication of a gene-diet interaction in 3 independent populations
-
Corella D, Peloso G, Arnett DK, et al. APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. Arch Intern Med 2009; 169:1897-1906.
-
(2009)
Arch Intern Med
, vol.169
, pp. 1897-1906
-
-
Corella, D.1
Peloso, G.2
Arnett, D.K.3
-
55
-
-
67651216024
-
NRXN3 is a novel locus for waist circumference: A genome-wide association study from the CHARGE Consortium
-
Heard-Costa NL, Zillikens MC, Monda KL, et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet 2009; 5:e1000539.
-
(2009)
PLoS Genet
, vol.5
-
-
Heard-Costa, N.L.1
Zillikens, M.C.2
Monda, K.L.3
-
56
-
-
72749087085
-
CLOCK genetic variation and metabolic syndrome risk: Modulation by monounsaturated fatty acids
-
Garaulet M, Lee YC, Shen J, et al. CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am J Clin Nutr 2009; 90:1466-1475.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 1466-1475
-
-
Garaulet, M.1
Lee, Y.C.2
Shen, J.3
-
57
-
-
78649754353
-
ADAM17-i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study
-
[Epub ahead of print] doi:10.1016/j.numecd.2009.06.011
-
Junyent M, Parnell LD, Lai CQ, et al. ADAM17-i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study. Nutr Metab Cardiovasc Dis 2009 [Epub ahead of print] doi:10.1016/j.numecd.2009.06.011.
-
(2009)
Nutr Metab Cardiovasc Dis
-
-
Junyent, M.1
Parnell, L.D.2
Lai, C.Q.3
-
58
-
-
69349107471
-
Common body mass index-associated variants confer risk of extreme obesity
-
Cotsapas C, Speliotes EK, Hatoum IJ, et al. Common body mass index-associated variants confer risk of extreme obesity. Hum Mol Genet 2009; 18:3502-3507.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3502-3507
-
-
Cotsapas, C.1
Speliotes, E.K.2
Hatoum, I.J.3
-
59
-
-
18944392912
-
A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis
-
DOI 10.1016/j.jacc.2005.01.051, PII S0735109705005176
-
Chen SN, Ballantyne CM, Gotto AM Jr, et al. A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol 2005; 45:1611-1619. (Pubitemid 40704495)
-
(2005)
Journal of the American College of Cardiology
, vol.45
, Issue.10
, pp. 1611-1619
-
-
Chen, S.N.1
Ballantyne, C.M.2
Gotto Jr., A.M.3
Tan, Y.4
Willerson, J.T.5
Marian, A.J.6
-
60
-
-
13944265645
-
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
-
Cohen J, Pertsemlidis A, Kotowski IK, et al. Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. Nat Genet 2005; 37:161-165.
-
(2005)
Nat Genet
, vol.37
, pp. 161-165
-
-
Cohen, J.1
Pertsemlidis, A.2
Kotowski, I.K.3
-
61
-
-
0037399153
-
Apolipoprotein A-II: Beyond genetic associations with lipid disorders and insulin resistance
-
DOI 10.1097/00041433-200304000-00008
-
Kalopissis AD, Pastier D, Chambaz J. Apolipoprotein A-II: beyond genetic associations with lipid disorders and insulin resistance. Curr Opin Lipidol 2003; 14:165-172. (Pubitemid 36521187)
-
(2003)
Current Opinion in Lipidology
, vol.14
, Issue.2
, pp. 165-172
-
-
Kalopissis, A.-D.1
Pastier, D.2
Chambaz, J.3
-
62
-
-
0033960706
-
Leptin, peroxisome proliferator-activated receptor-γ, and CCAAT/enhancer binding protein-α mRNA expression in adipose tissue of humans and their relation to cardiovascular risk factors
-
Krempler F, Breban D, Oberkofler H, et al. Leptin, peroxisome proliferator-activated receptor-gamma, and CCAAT/enhancer binding protein-alpha mRNA expression in adipose tissue of humans and their relation to cardiovascular risk factors. Arterioscler Thromb Vasc Biol 2000; 20:443-449. (Pubitemid 30086102)
-
(2000)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.20
, Issue.2
, pp. 443-449
-
-
Krempler, F.1
Breban, D.2
Oberkofler, H.3
Esterbauer, H.4
Hell, E.5
Paulweber, B.6
Patsch, W.7
-
63
-
-
76749155514
-
A composite of multiple signals distinguishes causal variants in regions of positive selection
-
(in press) doi:10.1126/science.1183863
-
Grossman SR, Shylakhter I, Karlsson EK, et al. A composite of multiple signals distinguishes causal variants in regions of positive selection. Science 2010; (in press) doi:10.1126/science.1183863.
-
(2010)
Science
-
-
Grossman, S.R.1
Shylakhter, I.2
Karlsson, E.K.3
|