The inositol phosphatase SHIP2 negatively regulates insulin/IGF-I actions implicated in neuroprotection and memory function in mouse brain

Molecular Endocrinology

Volumn 24, Issue 10, 2010, Pages 1965-1977

  Soeda, Yoshiyuki ^a   Tsuneki, Hiroshi ^a   Muranaka, Hayato ^a   Mori, Norihiko ^a   Hosoh, Shuji ^a   Ichihara, Yoshinori ^a   Kagawa, Syota ^a   Wang, Xu ^a   Toyooka, Naoki ^a   Takamura, Yusaku ^a   Uwano, Teruko ^a   Nishijo, Hisao ^a   Wada, Tsutomu ^a   Sasaoka, Toshiyasu ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AS 1949490; ENZYME INHIBITOR; MESSENGER RNA; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; RECOMBINANT HUMAN INSULIN; RECOMBINANT SOMATOMEDIN C; SH2 CONTAINING INOSITOL 5' PHOSPHATASE 2; SOMAZON; UNCLASSIFIED DRUG;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN DYSFUNCTION; CEREBELLUM; CONTROLLED STUDY; GENE EXPRESSION; INSULIN RESISTANCE; MALE; MAZE TEST; MEMORY; MEMORY DISORDER; MOUSE; MUTANT; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROPROTECTION; NICK END LABELING; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECOGNITION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

AGING; ANIMALS; BRAIN; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; MEMORY; MEMORY DISORDERS; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; NEURONAL PLASTICITY; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHORIC MONOESTER HYDROLASES; SIGNAL TRANSDUCTION;

MUS; MUS MUSCULUS;

EID: 77957359962     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0163     Document Type: Article

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