Gene-environment interaction of child temperament

Journal of Developmental and Behavioral Pediatrics

Volumn 31, Issue 7, 2010, Pages 545-554

  Ivorra, Jose Luis ^a   Sanjuan, Julio ^a   Jover, Manuel ^b   Carot, Jose Miguel ^c   Frutos, Rosa De ^a   Molto, Maria Dolores ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^c UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

Author keywords

gene environment interaction; genetic polymorphisms; infant irritability; mother's anxiety

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); DOPAMINE 4 RECEPTOR; DRD4 PROTEIN, HUMAN; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

ADULT; ANXIETY; ARTICLE; CHILD BEHAVIOR; ENVIRONMENT; FEMALE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; HUMAN; MALE; MATERNAL BEHAVIOR; MOTHER; MOTHER CHILD RELATION; NEWBORN; PREGNANCY; PROSPECTIVE STUDY; PSYCHOLOGICAL ASPECT; PUERPERIUM; RISK FACTOR; TEMPERAMENT; TIME;

ADULT; ANXIETY; ENVIRONMENT; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT BEHAVIOR; INFANT, NEWBORN; MALE; MATERNAL BEHAVIOR; MONOAMINE OXIDASE; MOTHER-CHILD RELATIONS; MOTHERS; POLYMORPHISM, GENETIC; POSTPARTUM PERIOD; PREGNANCY; PROSPECTIVE STUDIES; RECEPTORS, DOPAMINE D4; RISK FACTORS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TEMPERAMENT; TIME FACTORS;

EID: 77957341463     PISSN: 0196206X     EISSN: None     Source Type: Journal    
DOI: 10.1097/DBP.0b013e3181ee4072     Document Type: Article

References (68)

1. Fox NA. Temperament and regulation of emotion in the first years of life. Pediatrics. 1998;102:1230-1235
2. Beck CT. A meta-analysis of the relationships between postpartum depression and infant temperament. Nurse Res. 1996;45:225-230.
3. Austin MP, Hadzi-Pavlovic D, Leader L. Saint K, Parker G. Maternal trait anxiety, depression and life event stress in pregnancy: relationships with infant temperament. Early Hum Dev. 2005;81:183-190.
4. Kaplan LA, Evans L, Monk C. Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant behavioural regulation: Can pre natal programming be modified? Early Hum Dev. 2008;84:249-256.
5. Goodwin R, Meyer S, Thompson RA, Hayes R. Self-understanding in early childhood: associations with child attachment security and maternal negative affect. Attach Hum Dev. 2008;10:433-450.
6. Shamir-Essakow G, Ungerer JA, Rapee RM, Safier R. Caregiving representations of mothers of behaviorally inhibited and uninhibited preschool children. Dev Psychol. 2004;40:899-910.
7. Saudino KJ, Cherny SS, Plomin R. Parent ratings of temperament in twins: explaining the 'too low' DZ correlations. Twin Res. 2000;3:224-233.
8. Saudino KJ. Behavioral genetics and child temperament. J Dev Behav Pediatr. 2005;26:214-223
9. Ivorra-Martinez J, Gilabert-Juan J, Moltó-Ruiz MD, Sanjuán J. [The genetics of child temperament.] Rev Neurol. 2007;45:418-423
10. Ebstein RP, Levine J, Geller V, Auerbach J, Gritsenko I, Belmaker RH. Dopamine D4 receptor and serotonin transporter promoter in the determination of neonatal temperament. Mol Psychiatry. 1998;3:238-246.
11. Auerbach J, Geller V, Lezer S, et al. Dopamine D4 receptor (D4DR) and serotonin transporter promoter (5-HTTLPR) polymorphisms in the determination of temperament in 2-month-old infants. Mol Psychiatry. 1999;4:369-373
12. Lakatos K, Toth I, Nemoda Z, Ney K, Sasvari-Szekely M, Gervai J. Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants. Mol Psychiatry. 2000;5:633-637.
13. Auerbach JG, Faroy M, Ebstein R, Kahana M, Levine J. The association of the dopamine D4 receptor gene (DRD4) and the serotonin transporter promoter gene (5-HTTLPR) with temperament in 12-month-old infants. J Child Psychol Psychiatry. 2001;42:777-783.
14. Arbelle S, Benjamin J, Golin M, Kremer I, Belmaker RH, Ebstein RP. Relation of shyness in grade school children to the genotype for the long form of the serotonin transporter promoter region polymorphism. Am J Psychiatry. 2003;160:671-676.
15. Lakatos K, Nemoda Z, Birkas E, et al. Association of D4 dopamine receptor gene and serotonin transporter promoter polymorphisms with infants' response to novelty. Mol Psychiatry. 2003;8:90-97.
16. Bakermans-Kranenburg MJ, Van Ijzendoorn MH. No association of the dopamine D4 receptor (DRD4) and-521 C/T promoter polymorphisms with infant attachment disorganization. Attach Hum Dev. 2004;6:211-218.
17. Davidge KM, Atkinson L, Douglas L, et al. Association of the serotonin transporter and 5HT1Dbeta receptor genes with extreme, persistent and pervasive aggressive behaviour in children. Psychiatr Genet. 2004;14:143-146.
18. Battaglia M, Ogliari A, Zanoni A, et al. Influence of the serotonin transporter promoter gene and shyness on children's cerebral responses to facial expressions. Arch Gen Psychiatry. 2005;62:85-94.
19. Fox NA, Nichols KE, Henderson HA, et al. Evidence for a geneenvironment interaction in predicting behavioral inhibition in middle childhood. Psychol Sci. 2005;16:921-926.
20. de Boer L, Röder I, Wit JM. Psychosocial, cognitive, and motor functioning in patients with suspected Sotos syndrome: a comparison between patients with and without NSD1 gene alterations. Dev Med Child Neurol. 2006;48:582-588.
21. Beitchman JH, Baldassarra L, Mik H, et al. Serotonin transporter polymorphisms and persistent, pervasive childhood aggression. Am J Psychiatry. 2006;163:1103-1105.
22. Kim-Cohen J, Caspi A, Taylor A, et al. MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. Mol Psychiatry. 2006;11:903-913.
23. Van Ijzendoorn MH, Bakermans-Kranenburg MJ. DRD4 7-repeat polymorphism moderates the association between maternal unresolved loss or trauma and infant disorganization. Attach Hum Dev. 2006;8:291-307.
24. Hayden EP, Dougherty LR, Maloney B, et al. Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: a multimethod association study. Psychiatr Genet. 2007;17:135-142.
25. Gervai J, Novak A, Lakatos K, et al. Infant genotype may moderate sensitivity to maternal affective communications: attachment disorganization, quality of care, and the DRD4 polymorphism. Social Neurosci. 2007;2:307-319.
26. Becker K, El-Faddagh M, Schmidt MH, Laucht M. Is the serotonin transporter polymorphism (5-HTTLPR) associated with harm avoidance and internalising problems in childhood and adolescence? J Neural Transm. 2007;114:395-402.
27. Sheese BE, Voelker PM, Rothbart MK, Posner MI. Parenting quality interacts with genetic variation in dopamine receptor D4 to influence temperament in early childhood. Dev Psychopathol. 2007;19:1039-1046.
28. Schmidt LA, Fox NA, Hamer DH. Evidence for a gene-gene interaction in predicting children's behavior problems: association of serotonin transporter short and dopamine receptor D4 long genotypes with internalizing and externalizing behaviors in typically developing 7-year-olds. Dev Psychopathol. 2007;19:1105-1116.
29. Mills-Koonce WR, Propper CB, Gariepy JL, Blair C, Garrett-Peters P, Cox MJ. Bidirectional genetic and environmental influences on mother and child behavior: the family system as the unit of analyses. Dev Psychopathol. 2007;19:1073-1087.
30. Kochanska G, Philibert RA, Barry RA. Interplay of genes and early mother-child relationship in the development of selfregulation from toddler to preschool age. J Child Psychol Psychiatry. 2009;50:1331-1338.
31. Pauli-Pott U, Friedl S, Hinney A, Hebebrand J. Serotonin transporter gene polymorphism (5-HTTLPR), environmental conditions, and developing negative emotionality and fear in early childhood. J Neural Transm. 2009;116:503-512.
32. Voelker P, Sheese BE, Rothbart MK, Posner MI. Variations in catechol-O-methyltransferase gene interact with parenting to influence attention in early development. Neuroscience. 2009;164:121-130.
33. Asghari V, Sanyal S, Buchwalt S, Paterson A, Jovanovic V, Van Tol HH. Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants. J Neurochem. 1995;65:1157-1165.
34. Deckert J, Catalano M, Syagailo YV, et al. Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Hum Mol Genet. 1999;8:621-624.
35. Fiskerstrand CE, Lovejoy EA, Quinn JP. An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells. FEBS Lett. 1999;458:171-174.
36. Barry RA, Kochanska G, Philibert RA. G x E interaction in the organization of attachment: mothers' responsiveness as a moderator of children's genotypes. J Child Psychol Psychiatry. 2008;49:1313-1320.
37. Barr CS, Newman TK, Shannon C, et al. Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitaryadrenal axis response to stress in infant macaques. Biol Psychiatry. 2004;55:733-738.
38. Champoux M, Bennett A, Shannon C, Higley JD, Lesch KP, Suomi SJ. Serotonin transporter gene polymorphism, differential early rearing, and behavior in rhesus monkey neonates. Mol Psychiatry. 2002;7:1058-1063.
39. Suomi SJ. Risk, resilience, and gene x environment interactions in rhesus monkeys. Ann N Y Acad Sci. 2006;1094:52-62.
40. Bennett AJ, Lesch KP, Heils A, et al. Early experience and serotonin transporter gene variation interact to influence primate CNS function. Mol Psychiatry. 2002;7:118-122.
41. Sanjuan J, Martin-Santos R, Garcia-Esteve L, et al. Mood changes after delivery: role of the serotonin transporter gene. Br J Psychiatry. 2008;193:383-388.
42. Brazelton TB, Nugent JK. Neonatal Behavioral Assessment Scale (Clinics in Developmental Medicine). 3rd ed. Cambridge, United Kingdom: Mac Keith Press; 1995.
43. Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry. 1987;150:782-786.
44. García-Esteve L, Ascaso C, Ojuel J, Navarro P. Validation of the Edinburgh Postnatal Depression Scale (EPDS) in Spanish mothers. J. Affect Disord. 2003;75:71-76.
45. Tenenbaum G, Furst D, Weingarten GA. Statistical reevaluation of the STAI anxiety questionnaire. J Clin Psychol. 1985;41:239-244.
46. Bayle FJ, Leroy S, Gourion D, et al. 5HTTLPR polymorphism in schizophrenic patients: further support for association with violent suicide attempts. Am J Med Genet B Neuropsychiatr Genet. 2003;119:13-17.
47. Ogilvie AD, Battersby S, Bubb VJ, et al. Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet. 1996;347:731-733.
48. Van Tol HH, Wu CM, Guan HC, et al. Multiple dopamine D4 receptor variants in the human population. Nature. 1992;358:149-152.
49. Sabol SZ, Hu S, Hamer D. A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet. 1998;103:273-279.
50. Heils A, Teufel A, Petri S, et al. Allelic variation of human serotonin transporter gene expression. J Neurochem. 1996;66:2621-2624.
51. Lesch KP, Bengel D, Heils A, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;274:1527-1531.
52. Edhborg M, Seimyr L, Lundh W. Fussy child-difficult parenthood? Comparisons between families with a 'depressed' mother and non-depressed mother 2 months postpartum. J Reprod Infant Psychol. 2000;18:225-238.
53. Righetti-Veltema M, Conne-Perréard E, Bousquet A, Manzano J. Postpartum depression and mother-infant relationship at 3 months old. J Affect Disord. 2002;70:291-306.
54. Kagan J, Snidman N. Early childhood predictors of adult anxiety disorders. Biol Psychiatry. 1999;46:1536-1541.
55. Kagan J. Biology, context, and developmental inquiry. Annu Rev Psychol. 2003;54:1-23
56. Reichborn-Kjennerud T. Genetics of personality disorders. Psychiatr Clin North Am. 2008;31:421-440.
57. Kochanska G, Aksan N. Development of mutual responsiveness between parents and their young children. Child Dev. 2004;75:1657-1676.
58. Hane AA, Fox NA. Ordinary variations in maternal caregiving influence human infants' stress reactivity. Psychol Sci. 2006;17:550-556.
59. Macguire CM, Bruil J, Wit JM, Walther FJ. Reading preterm infants behavioral cues: An intervention study with parents of premature infants born <32 weeks. Early Hum Dev. 2007;83:419-424.
60. Reiss D, Leve LD. Genetic expression outside the skin: clues to mechanisms of Genotype x Environment interaction. Dev Psychopathol. 2007;19:1005-1027.
61. Uher R, McGuffin P. The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry. 2008;13:131-146.
62. Worobey J. Convergence among assessments of temperament in the first month. Child Dev. 1996;57:47-55
63. Hane AA, Fox NA, Polak-Toste C, Ghera MM, Guner BM. Contextual basis of maternal perceptions of infant temperament. Dev Psychol. 2006;42:1077-1088.
64. Pauli-Pott U, Mertesacker B, Beckmann D. [Comparing assessment methods of infant emotionality.] Z Kinder Jugendpsychiatr Psychother. 2005;33:123-135
65. Hu XZ, Zipsky RH, Zhu G, et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Human Genet. 2006;78:815-826.
66. Wendland JR, Moya PR, Kruse MR, et al. A novel, putative gainof-function haplotype at SLC6A4 associates with obsessivecompulsive disorder. Hum Mol Genet. 2008;17:717-723.
67. McGrath JM, Records K, Rice M. Maternal depression and infant temperament characteristics. Infant Behav Dev. 2008;31:71-80.
68. Coplan JD, Altemus M, Mathew SJ, et al. Synchronized maternalinfant elevations of primate CSF CRF concentrations in response to variable foraging demand. CNS Spectr. 2005;10:530-536.