메뉴 건너뛰기




Volumn 51, Issue 9, 2010, Pages 4809-4820

Altered expression of metallothionein-i and-ii and their receptor megalin in inherited photoreceptor degeneration

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOLECTIN B4; MEGALIN; METALLOTHIONEIN I; METALLOTHIONEIN II; AVIDIN; BIOLOGICAL MARKER; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; METALLOTHIONEIN; METALLOTHIONEIN 2 PROTEIN, RAT; NERVE PROTEIN; PDE6B PROTEIN, MOUSE; PHOSPHODIESTERASE VI;

EID: 77957338177     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-5073     Document Type: Article
Times cited : (24)

References (94)
  • 2
    • 34147097300 scopus 로고    scopus 로고
    • Retinitis pigmentosa
    • Hamel C. Retinitis pigmentosa. Orphanet J Rare Dis. 2006; 1: 40.
    • (2006) Orphanet J Rare Dis , vol.1 , pp. 40
    • Hamel, C.1
  • 3
    • 0031937530 scopus 로고    scopus 로고
    • Protection of mouse photoreceptors by survival factors in retinal degenerations
    • LaVail MM, Yasumura D, Matthes MT, et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci. 1998; 39: 592-602.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 592-602
    • Lavail, M.M.1    Yasumura, D.2    Matthes, M.T.3
  • 4
    • 33644872951 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants
    • Sieving PA, Caruso RC, Tao W, et al. Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants. Proc Natl Acad Sci U S A. 2006; 103: 3896-3901.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 3896-3901
    • Sieving, P.A.1    Caruso, R.C.2    Tao, W.3
  • 5
    • 0035903763 scopus 로고    scopus 로고
    • Lens epithelium-derived growth factor (LEDGF) delays photoreceptor degeneration in explants of rd/rd mouse retina
    • Ahuja P, Caffé AR, Holmqvist I, et al. Lens epithelium-derived growth factor (LEDGF) delays photoreceptor degeneration in explants of rd/rd mouse retina. Neuroreport. 2001; 12: 2951-2955.
    • (2001) Neuroreport , vol.12 , pp. 2951-2955
    • Ahuja, P.1    Caffé, A.R.2    Holmqvist, I.3
  • 6
    • 26244460046 scopus 로고    scopus 로고
    • Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?
    • Delyfer MN, Simonutti M, Neveux N, Léveillard T, Sahel JA. Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST? Mol Vis. 2005; 11: 677-687.
    • (2005) Mol Vis , vol.11 , pp. 677-687
    • Delyfer, M.N.1    Simonutti, M.2    Neveux, N.3    Léveillard, T.4    Sahel, J.A.5
  • 7
    • 33846018863 scopus 로고    scopus 로고
    • CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina
    • Azadi S, Johnson LE, Paquet-Durand F, et al. CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina. Brain Res. 2007; 1129: 116-129.
    • (2007) Brain Res , vol.1129 , pp. 116-129
    • Azadi, S.1    Johnson, L.E.2    Paquet-Durand, F.3
  • 8
    • 0032555204 scopus 로고    scopus 로고
    • The elusive function of metallothioneins
    • Palmiter RD. The elusive function of metallothioneins. Proc Natl Acad Sci U S A. 1998; 95: 8428-8430.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8428-8430
    • Palmiter, R.D.1
  • 9
    • 0035872463 scopus 로고    scopus 로고
    • Roles of the metallothionein family of proteins in the central nervous system
    • Hidalgo J, Aschner M, Zatta P, Vasák M. Roles of the metallothionein family of proteins in the central nervous system. Brain Res Bull. 2001; 55: 133-145.
    • (2001) Brain Res Bull , vol.55 , pp. 133-145
    • Hidalgo, J.1    Aschner, M.2    Zatta, P.3    Vasák, M.4
  • 11
    • 0345276583 scopus 로고    scopus 로고
    • Signaling events for metallothionein induction
    • Haq F, Mahoney M, Koropatnick J. Signaling events for metallothionein induction. Mutat Res. 2003; 533: 211-226.
    • (2003) Mutat Res , vol.533 , pp. 211-226
    • Haq, F.1    Mahoney, M.2    Koropatnick, J.3
  • 12
    • 33646268801 scopus 로고    scopus 로고
    • Metallothioneins are multipurpose neuroprotectants during brain pathology
    • Penkowa M. Metallothioneins are multipurpose neuroprotectants during brain pathology. FEBS Lett J. 2006; 273: 1857-1870.
    • (2006) FEBS Lett J , vol.273 , pp. 1857-1870
    • Penkowa, M.1
  • 13
    • 85128738703 scopus 로고    scopus 로고
    • The balance between life and death of cells: Roles of metallothioneins
    • Nielsen AE, Bohr A, Penkowa M. The balance between life and death of cells: roles of metallothioneins. Biomark Insights. 2007; 1: 99-111.
    • (2007) Biomark Insights , vol.1 , pp. 99-111
    • Nielsen, A.E.1    Bohr, A.2    Penkowa, M.3
  • 14
    • 67649640809 scopus 로고    scopus 로고
    • Structure and functions of vertebrate metallothioneins
    • Sigel A, Sigel H, Sigel RKO, eds., Cambridge, UK: The Royal Society of Chemistry
    • Hidalgo J, Chung R, Penkowa M, Vasák M. Structure and functions of vertebrate metallothioneins. In: Sigel A, Sigel H, Sigel RKO, eds. Metal Ions in Life Sciences: Metallothioneins and Related Chelators. Vol.5. Cambridge, UK: The Royal Society of Chemistry. 2009: 279-317.
    • (2009) Metal Ions in Life Sciences: Metallothioneins and Related Chelators , vol.5 , pp. 279-317
    • Hidalgo, J.1    Chung, R.2    Penkowa, M.3    Vasák, M.4
  • 16
    • 0032584166 scopus 로고    scopus 로고
    • Thiolate ligands in metallothionein confer redox activity on zinc clusters
    • Maret W, Vallee BL. Thiolate ligands in metallothionein confer redox activity on zinc clusters. Proc Natl Acad Sci U S A. 1998; 95: 3478-3482.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3478-3482
    • Maret, W.1    Vallee, B.L.2
  • 17
    • 0036239958 scopus 로고    scopus 로고
    • Recent studies on metallothionein: Protection against toxicity of heavy metals and oxygen free radicals
    • Sato M, Kondoh M. Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals. Tohoku J Exp Med. 2002; 196: 9-22.
    • (2002) Tohoku J Exp Med , vol.196 , pp. 9-22
    • Sato, M.1    Kondoh, M.2
  • 18
    • 33846260825 scopus 로고    scopus 로고
    • Metallothioneins I and II: Neuroprotective significance during CNS pathology
    • Stankovic RK, Chung RS, Penkowa M. Metallothioneins I and II: neuroprotective significance during CNS pathology. Int J Biochem Cell Biol. 2007; 39: 484-489.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 484-489
    • Stankovic, R.K.1    Chung, R.S.2    Penkowa, M.3
  • 19
    • 70449726833 scopus 로고    scopus 로고
    • Metallothionein-I+II in neuroprotection
    • Pedersen MØ, Jensen R, Pedersen DS, et al. Metallothionein-I+II in neuroprotection. Biofactors. 2009; 35: 315-325.
    • (2009) Biofactors , vol.35 , pp. 315-325
    • Pedersen, M.1    Jensen, R.2    Pedersen, D.S.3
  • 20
    • 0025845862 scopus 로고
    • Immunohistochemical localization of metallothionein in the eye of rats
    • Nishimura H, Nishimura N, Kobayashi S, Tohyama C. Immunohistochemical localization of metallothionein in the eye of rats. Histochemistry. 1991; 95: 535-539.
    • (1991) Histochemistry , vol.95 , pp. 535-539
    • Nishimura, H.1    Nishimura, N.2    Kobayashi, S.3    Tohyama, C.4
  • 21
    • 0026572595 scopus 로고
    • Metallothionein in human retinal pigment epithelial cells: Expression, induction and zinc uptake
    • Oliver PD, Tate DJ, Newsome DA. Metallothionein in human retinal pigment epithelial cells: expression, induction and zinc uptake. Curr Eye Res. 1992; 11: 183-188.
    • (1992) Curr Eye Res , vol.11 , pp. 183-188
    • Oliver, P.D.1    Tate, D.J.2    Newsome, D.A.3
  • 22
    • 0027264819 scopus 로고
    • Metallothionein shows an agerelated decrease in human macular retinal pigment epithelium
    • Tate DJ, Newsome DA, Oliver PD. Metallothionein shows an agerelated decrease in human macular retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1993; 34: 2348-2351.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 2348-2351
    • Tate, D.J.1    Newsome, D.A.2    Oliver, P.D.3
  • 23
    • 0028792399 scopus 로고
    • Influence of zinc on selected cellular functions of cultured human retinal pigment epithelium
    • Tate DJ, Miceli MV, Newsome DA, Alcock NW, Oliver PD. Influence of zinc on selected cellular functions of cultured human retinal pigment epithelium. Curr Eye Res. 1995; 14: 897-903.
    • (1995) Curr Eye Res , vol.14 , pp. 897-903
    • Tate, D.J.1    Miceli, M.V.2    Newsome, D.A.3    Alcock, N.W.4    Oliver, P.D.5
  • 24
    • 0033055792 scopus 로고    scopus 로고
    • Expression of antioxidant protective proteins in the rat retina during prenatal and postnatal development
    • Chen W, Hunt DM, Lu H, Hunt RC. Expression of antioxidant protective proteins in the rat retina during prenatal and postnatal development. Invest Ophthalmol Vis Sci. 1999; 40: 744-751.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 744-751
    • Chen, W.1    Hunt, D.M.2    Lu, H.3    Hunt, R.C.4
  • 25
    • 0035996278 scopus 로고    scopus 로고
    • Expression of metallothionein isoforms in human chorioretinal complex
    • Tate DJ, Miceli MV, Newsome DA. Expression of metallothionein isoforms in human chorioretinal complex. Curr Eye Res. 2002; 24: 12-25.
    • (2002) Curr Eye Res , vol.24 , pp. 12-25
    • Tate, D.J.1    Miceli, M.V.2    Newsome, D.A.3
  • 26
    • 33749132814 scopus 로고    scopus 로고
    • Metallothionein, an endogenous antioxidant, protects against retinal neuron damage in mice
    • Suemori S, Shimazawa M, Kawase K, et al. Metallothionein, an endogenous antioxidant, protects against retinal neuron damage in mice. Invest Ophthalmol Vis Sci. 2006; 47: 3975-3982.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3975-3982
    • Suemori, S.1    Shimazawa, M.2    Kawase, K.3
  • 27
    • 4344605052 scopus 로고    scopus 로고
    • Increased metallothionein in light damaged mouse retinas
    • Chen L, Wu W, Dentchev T, Wong R, Dunaief JL. Increased metallothionein in light damaged mouse retinas. Exp Eye Res. 2004; 79: 287-293.
    • (2004) Exp Eye Res , vol.79 , pp. 287-293
    • Chen, L.1    Wu, W.2    Dentchev, T.3    Wong, R.4    Dunaief, J.L.5
  • 28
    • 3242889113 scopus 로고    scopus 로고
    • Temporal changes in gene expression after injury in the rat retina
    • Vázquez-Chona F, Song BK, Geisert EE. Temporal changes in gene expression after injury in the rat retina. Invest Ophthalmol Vis Sci. 2004; 45: 2737-2746.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2737-2746
    • Vázquez-Chona, F.1    Song, B.K.2    Geisert, E.E.3
  • 29
    • 41149111103 scopus 로고    scopus 로고
    • Analysis of the retinal gene expression profile after hypoxic preconditioning identifies candidate genes for neuroprotection
    • Thiersch M, Raffelsberger W, Frigg R, et al. Analysis of the retinal gene expression profile after hypoxic preconditioning identifies candidate genes for neuroprotection. BMC Genomics. 2008; 9: 73.
    • (2008) BMC Genomics , vol.9 , pp. 73
    • Thiersch, M.1    Raffelsberger, W.2    Frigg, R.3
  • 30
    • 0029936705 scopus 로고    scopus 로고
    • Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys. II. Suppression of metallothionein synthesis in the retina in oxidative stress
    • Nicolas MG, Fujiki K, Murayama K, et al. Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys. II. Suppression of metallothionein synthesis in the retina in oxidative stress. Exp Eye Res. 1996; 62: 399-408.
    • (1996) Exp Eye Res , vol.62 , pp. 399-408
    • Nicolas, M.G.1    Fujiki, K.2    Murayama, K.3
  • 31
    • 0036343594 scopus 로고    scopus 로고
    • Metallothionein protects retinal pigment epithelial cells against apoptosis and oxidative stress
    • Lu H, Hunt DM, Ganti R, et al. Metallothionein protects retinal pigment epithelial cells against apoptosis and oxidative stress. Exp Eye Res. 2002; 74: 83-92.
    • (2002) Exp Eye Res , vol.74 , pp. 83-92
    • Lu, H.1    Hunt, D.M.2    Ganti, R.3
  • 32
    • 33750533146 scopus 로고    scopus 로고
    • Reduction of p66Shc suppresses oxidative damage in retinal pigmented epithelial cells and retina
    • Wu Z, Rogers B, Kachi S, Hackett SF, Sick A, Campochiaro PA. Reduction of p66Shc suppresses oxidative damage in retinal pigmented epithelial cells and retina. J Cell Physiol. 2006; 209: 996-1005.
    • (2006) J Cell Physiol , vol.209 , pp. 996-1005
    • Wu, Z.1    Rogers, B.2    Kachi, S.3    Hackett, S.F.4    Sick, A.5    Campochiaro, P.A.6
  • 34
    • 47249146602 scopus 로고    scopus 로고
    • Redefining the role of metallothionein within the injured brain: Extracellular metallothioneins play an important role in the astrocyte-neuron response to injury
    • Chung RS, Penkowa M, Dittmann J, et al. Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury. J Biol Chem. 2008; 283: 15349-15358.
    • (2008) J Biol Chem , vol.283 , pp. 15349-15358
    • Chung, R.S.1    Penkowa, M.2    Dittmann, J.3
  • 35
    • 84984766757 scopus 로고    scopus 로고
    • Megalin and cubilin: Multifunctional endocytic receptors
    • Christensen EI, Birn H. Megalin and cubilin: multifunctional endocytic receptors. Nat Rev Mol Cell Biol. 2002; 3: 256-266.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 256-266
    • Christensen, E.I.1    Birn, H.2
  • 36
    • 27144457812 scopus 로고    scopus 로고
    • Molecular mechanisms of lipoprotein receptor signalling
    • May P, Herz J, Bock HH. Molecular mechanisms of lipoprotein receptor signalling. Cell Mol Life Sci. 2005; 62: 2325-2338.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2325-2338
    • May, P.1    Herz, J.2    Bock, H.H.3
  • 37
    • 37249056581 scopus 로고    scopus 로고
    • Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family
    • Ambjørn M, Asmussen JW, Lindstam M, et al. Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family. J Neurochem. 2008; 104: 21-37.
    • (2008) J Neurochem , vol.104 , pp. 21-37
    • Ambjørn, M.1    Asmussen, J.W.2    Lindstam, M.3
  • 38
    • 0024990758 scopus 로고
    • Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase
    • Bowes C, Li T, Danciger M, Baxter LC, Applebury ML, Farber DB. Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase. Nature. 1990; 347: 677-680.
    • (1990) Nature , vol.347 , pp. 677-680
    • Bowes, C.1    Li, T.2    Danciger, M.3    Baxter, L.C.4    Applebury, M.L.5    Farber, D.B.6
  • 39
    • 0019364889 scopus 로고
    • Absence of receptor outer segments in the retina of rds mutant mice
    • Sanyal S, Jansen HG. Absence of receptor outer segments in the retina of rds mutant mice. Neurosci Lett. 1981; 21: 23-26.
    • (1981) Neurosci Lett , vol.21 , pp. 23-26
    • Sanyal, S.1    Jansen, H.G.2
  • 40
    • 0034163837 scopus 로고    scopus 로고
    • Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat
    • D'Cruz PM, Yasumura D, Weir J, et al. Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat. Hum Mol Genet. 2000; 9: 645-651.
    • (2000) Hum Mol Genet , vol.9 , pp. 645-651
    • D'cruz, P.M.1    Yasumura, D.2    Weir, J.3
  • 41
    • 0026659476 scopus 로고
    • Photoreceptor-specific mRNAs in mice carrying different allelic combinations at the rd and rds loci
    • Viczian A, Sanyal S, Toffenetti J, Chader GJ, Farber DB. Photoreceptor-specific mRNAs in mice carrying different allelic combinations at the rd and rds loci. Exp Eye Res. 1992; 54: 853-860.
    • (1992) Exp Eye Res , vol.54 , pp. 853-860
    • Viczian, A.1    Sanyal, S.2    Toffenetti, J.3    Chader, G.J.4    Farber, D.B.5
  • 42
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin J, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 1979; 18: 5294-5299.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.1    Przybyla, A.E.2    Macdonald, R.J.3    Rutter, W.J.4
  • 43
    • 10544256600 scopus 로고    scopus 로고
    • Expression monitoring by hybridization to high-density oligonucleotide arrays
    • Lockhart DJ, Dong H, Byrne MC, et al. Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol. 1996; 14: 1675-1680.
    • (1996) Nat Biotechnol , vol.14 , pp. 1675-1680
    • Lockhart, D.J.1    Dong, H.2    Byrne, M.C.3
  • 44
    • 24644512209 scopus 로고    scopus 로고
    • Simpleaffy: A BioConductor package for Affymetrix Quality Control and data analysis
    • Wilson CL, Miller CJ. Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis. Bioinformatics. 2005; 21: 3683-3685.
    • (2005) Bioinformatics , vol.21 , pp. 3683-3685
    • Wilson, C.L.1    Miller, C.J.2
  • 45
    • 38349137968 scopus 로고    scopus 로고
    • RReportGenerator: Automatic reports from routine statistical analysis using R
    • Raffelsberger W, Krause Y, Moulinier L, et al. RReportGenerator: automatic reports from routine statistical analysis using R. Bioinformatics. 2008; 24: 276-278.
    • (2008) Bioinformatics , vol.24 , pp. 276-278
    • Raffelsberger, W.1    Krause, Y.2    Moulinier, L.3
  • 46
    • 44049085003 scopus 로고    scopus 로고
    • RETINOBASE: A web database, data mining and analysis platform for gene expression data on retina
    • Kalathur RK, Gagniere N, Bertommier G, et al. RETINOBASE: a web database, data mining and analysis platform for gene expression data on retina. BMC Genomics. 2008; 9: 208.
    • (2008) BMC Genomics , vol.9 , pp. 208
    • Kalathur, R.K.1    Gagniere, N.2    Bertommier, G.3
  • 47
    • 67449086079 scopus 로고    scopus 로고
    • Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1 alpha expression in photoreceptors
    • Thiersch M, Lange C, Joly S, et al. Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1 alpha expression in photoreceptors. Eur J Neurosci. 2009; 29: 2291-2302.
    • (2009) Eur J Neurosci , vol.29 , pp. 2291-2302
    • Thiersch, M.1    Lange, C.2    Joly, S.3
  • 48
    • 18344375672 scopus 로고    scopus 로고
    • Role of metallothionein isoforms in bone formation processes in rat marrow mesenchymal stem cells in culture
    • Dohi Y, Shimaoka H, Ikeuchi M, Ohgushi H, Yonemasu K, Minami T. Role of metallothionein isoforms in bone formation processes in rat marrow mesenchymal stem cells in culture. Biol Trace Elem Res. 2005; 104: 57-70.
    • (2005) Biol Trace Elem Res , vol.104 , pp. 57-70
    • Dohi, Y.1    Shimaoka, H.2    Ikeuchi, M.3    Ohgushi, H.4    Yonemasu, K.5    Minami, T.6
  • 49
    • 0031984418 scopus 로고    scopus 로고
    • Direct detection of 8--oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues
    • Struthers L, Patel R, Clark J, Thomas S. Direct detection of 8--oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues. Anal Biochem. 1998; 255: 20-31.
    • (1998) Anal Biochem , vol.255 , pp. 20-31
    • Struthers, L.1    Patel, R.2    Clark, J.3    Thomas, S.4
  • 50
    • 33947543601 scopus 로고    scopus 로고
    • Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration
    • Sanz MM, Johnson LE, Ahuja S, Ekström PA, Romero J, van Veen T. Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration. Neuroscience. 2007; 145: 1120-1129.
    • (2007) Neuroscience , vol.145 , pp. 1120-1129
    • Sanz, M.M.1    Johnson, L.E.2    Ahuja, S.3    Ekström, P.A.4    Romero, J.5    van Veen, T.6
  • 51
    • 48049110299 scopus 로고    scopus 로고
    • Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay
    • Söderberg O, Leuchowius KJ, Gullberg M, et al. Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay. Methods. 2008; 45: 227-232.
    • (2008) Methods , vol.45 , pp. 227-232
    • Söderberg, O.1    Leuchowius, K.J.2    Gullberg, M.3
  • 53
    • 0027448769 scopus 로고
    • Localization and modulatory actions of zinc in vertebrate retina
    • Wu SM, Qiao X, Noebels JL, Yang XL. Localization and modulatory actions of zinc in vertebrate retina. Vision Res. 1993; 33: 2611-2616.
    • (1993) Vision Res , vol.33 , pp. 2611-2616
    • Wu, S.M.1    Qiao, X.2    Noebels, J.L.3    Yang, X.L.4
  • 54
    • 28444432986 scopus 로고    scopus 로고
    • Neuroimaging of zinc released by depolarization of rat retinal cells
    • Redenti S, Chappell RL. Neuroimaging of zinc released by depolarization of rat retinal cells. Vision Res. 2005; 45: 3520-3525.
    • (2005) Vision Res , vol.45 , pp. 3520-3525
    • Redenti, S.1    Chappell, R.L.2
  • 55
    • 0032887444 scopus 로고    scopus 로고
    • The localization of free zinc varies in rat photoreceptors during light and dark adaptation
    • Ugarte M, Osborne NN. The localization of free zinc varies in rat photoreceptors during light and dark adaptation. Exp Eye Res. 1999; 69: 459-461.
    • (1999) Exp Eye Res , vol.69 , pp. 459-461
    • Ugarte, M.1    Osborne, N.N.2
  • 56
    • 0035992379 scopus 로고    scopus 로고
    • Development of glutamatergic synapses in the rat retina: The postnatal expression of ionotropic glutamate receptor subunits
    • Hack I, Koulen P, Peichl L, Brandstätter JH. Development of glutamatergic synapses in the rat retina: the postnatal expression of ionotropic glutamate receptor subunits. Vis Neurosci. 2002; 19: 1-13.
    • (2002) Vis Neurosci , vol.19 , pp. 1-13
    • Hack, I.1    Koulen, P.2    Peichl, L.3    Brandstätter, J.H.4
  • 57
    • 0033588813 scopus 로고    scopus 로고
    • Distribution of metallothionein I _ II and vesicular zinc in the developing central nervous system: Correlative study in the rat
    • Penkowa M, Nielsen H, Hidalgo J, Bernth N, Moos T. Distribution of metallothionein I _ II and vesicular zinc in the developing central nervous system: correlative study in the rat. J Comp Neurol. 1999; 41: 303-318.
    • (1999) J Comp Neurol , vol.41 , pp. 303-318
    • Penkowa, M.1    Nielsen, H.2    Hidalgo, J.3    Bernth, N.4    Moos, T.5
  • 58
    • 0029074024 scopus 로고
    • Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
    • Stone J, Itin A, Alon T, et al. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci. 1995; 15: 4738-4747.
    • (1995) J Neurosci , vol.15 , pp. 4738-4747
    • Stone, J.1    Itin, A.2    Alon, T.3
  • 59
    • 0029149172 scopus 로고
    • Induction of metallothionein by thrombin in cultured vascular endothelial and smooth muscle cells
    • Kaji T, Yamamoto C, Suzuki M, et al. Induction of metallothionein by thrombin in cultured vascular endothelial and smooth muscle cells. Biol Pharm Bull. 1995; 18: 1272-1274.
    • (1995) Biol Pharm Bull , vol.18 , pp. 1272-1274
    • Kaji, T.1    Yamamoto, C.2    Suzuki, M.3
  • 60
    • 0017866791 scopus 로고
    • Differential effect of the rd mutation on rods and cones in the mouse retina
    • Carter-Dawson LD, LaVail MM, Sidman RL. Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Vis Sci. 1978; 17: 489-498.
    • (1978) Invest Ophthalmol Vis Sci , vol.17 , pp. 489-498
    • Carter-Dawson, L.D.1    Lavail, M.M.2    Sidman, R.L.3
  • 61
    • 33746773660 scopus 로고    scopus 로고
    • Antioxidants reduce cone cell death in a model of retinitis pigmentosa
    • Komeima K, Rogers BS, Lu L, Campochiaro PA. Antioxidants reduce cone cell death in a model of retinitis pigmentosa. Proc Natl Acad Sci U S A. 2006; 103: 11300-11305.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11300-11305
    • Komeima, K.1    Rogers, B.S.2    Lu, L.3    Campochiaro, P.A.4
  • 62
    • 33745827046 scopus 로고    scopus 로고
    • Müller cells in the healthy and diseased retina
    • Bringmann A, Pannicke T, Grosche J, et al. Müller cells in the healthy and diseased retina. Prog Retin Eye Res. 2006; 25: 397-424.
    • (2006) Prog Retin Eye Res , vol.25 , pp. 397-424
    • Bringmann, A.1    Pannicke, T.2    Grosche, J.3
  • 63
    • 11144273817 scopus 로고    scopus 로고
    • Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
    • Wenzel A, Grimm C, Samardzija M, Remé C. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog Retin Eye Res. 2005; 24: 275-306.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 275-306
    • Wenzel, A.1    Grimm, C.2    Samardzija, M.3    Remé, C.4
  • 65
    • 33751239138 scopus 로고    scopus 로고
    • Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors
    • Sanges D, Comitato A, Tammaro R, Marigo V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci U S A. 2006; 103: 17366-17371.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17366-17371
    • Sanges, D.1    Comitato, A.2    Tammaro, R.3    Marigo, V.4
  • 66
    • 0032881941 scopus 로고    scopus 로고
    • Retinitis pigmentosa: Rod photoreceptor rescue by a calcium-channel blocker in the rd mouse
    • Frasson M, Sahel JA, Fabre M, Simonutti M, Dreyfus H, Picaud S. Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse. Nat Med. 1999; 5: 1183-1187.
    • (1999) Nat Med , vol.5 , pp. 1183-1187
    • Frasson, M.1    Sahel, J.A.2    Fabre, M.3    Simonutti, M.4    Dreyfus, H.5    Picaud, S.6
  • 67
    • 33645748724 scopus 로고    scopus 로고
    • Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors
    • Farjo R, Skaggs JS, Nagel BA, et al. Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors. J Cell Biol. 2006; 173: 59-68.
    • (2006) J Cell Biol , vol.173 , pp. 59-68
    • Farjo, R.1    Skaggs, J.S.2    Nagel, B.A.3
  • 68
    • 0028323217 scopus 로고
    • Loss of diurnal arrestin gene expression in rds mutant mouse retinas
    • Agarwal N, Nir I, Papermaster DS. Loss of diurnal arrestin gene expression in rds mutant mouse retinas. Exp Eye Res. 1994; 58: 1-8.
    • (1994) Exp Eye Res , vol.58 , pp. 1-8
    • Agarwal, N.1    Nir, I.2    Papermaster, D.S.3
  • 69
    • 0027521914 scopus 로고
    • Apoptosis: Final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice
    • Chang GQ, Hao Y, Wong F. Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron. 1993; 11: 595-605.
    • (1993) Neuron , vol.11 , pp. 595-605
    • Chang, G.Q.1    Hao, Y.2    Wong, F.3
  • 71
    • 0344736812 scopus 로고    scopus 로고
    • Up-regulation of glial fibrillary acidic protein in response to retinal injury: Its potential role in glial remodeling and a comparison to vimentin expression
    • Lewis GP, Fisher SK. Up-regulation of glial fibrillary acidic protein in response to retinal injury: its potential role in glial remodeling and a comparison to vimentin expression. Int Rev Cytol. 2003; 230: 263-290.
    • (2003) Int Rev Cytol , vol.230 , pp. 263-290
    • Lewis, G.P.1    Fisher, S.K.2
  • 72
    • 0037337430 scopus 로고    scopus 로고
    • Accumulation of neurocan, a brain chondroitin sulfate proteoglycan, in association with the retinal vasculature in RCS rats
    • Zhang Y, Rauch U, Perez MT. Accumulation of neurocan, a brain chondroitin sulfate proteoglycan, in association with the retinal vasculature in RCS rats. Invest Ophthalmol Vis Sci. 2003; 44: 1252-1261.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 1252-1261
    • Zhang, Y.1    Rauch, U.2    Perez, M.T.3
  • 73
    • 0035012964 scopus 로고    scopus 로고
    • Electrophysiological properties of rat retinal Müller (glial) cells in postnatally developing and in pathologically altered retinae
    • Felmy F, Pannicke T, Richt JA, Reichenbach A, Guenther E. Electrophysiological properties of rat retinal Müller (glial) cells in postnatally developing and in pathologically altered retinae. Glia. 2001; 34: 190-199.
    • (2001) Glia , vol.34 , pp. 190-199
    • Felmy, F.1    Pannicke, T.2    Richt, J.A.3    Reichenbach, A.4    Guenther, E.5
  • 75
    • 0029988263 scopus 로고    scopus 로고
    • Neurochemical architecture of the normal and degenerating rat retina
    • Fletcher EL, Kalloniatis M. Neurochemical architecture of the normal and degenerating rat retina. J Comp Neurol. 1996; 376: 343-360.
    • (1996) J Comp Neurol , vol.376 , pp. 343-360
    • Fletcher, E.L.1    Kalloniatis, M.2
  • 76
    • 26244433170 scopus 로고    scopus 로고
    • Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina
    • Delyfer MN, Forster V, Neveux N, Picaud S, Léveillard T, Sahel JA. Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina. Mol Vis. 2005; 11: 688-696.
    • (2005) Mol Vis , vol.11 , pp. 688-696
    • Delyfer, M.N.1    Forster, V.2    Neveux, N.3    Picaud, S.4    Léveillard, T.5    Sahel, J.A.6
  • 77
    • 35148886412 scopus 로고    scopus 로고
    • Zinc release at the synaptic terminals of rod photoreceptors
    • Redenti S, Ripps H, Chappell RL. Zinc release at the synaptic terminals of rod photoreceptors. Exp Eye Res. 2007; 85: 580-584.
    • (2007) Exp Eye Res , vol.85 , pp. 580-584
    • Redenti, S.1    Ripps, H.2    Chappell, R.L.3
  • 78
    • 52049103341 scopus 로고    scopus 로고
    • Zinc-mediated feedback at the synaptic terminals of vertebrate photoreceptors
    • Chappell RL, Anastassov I, Lugo P, Ripps H. Zinc-mediated feedback at the synaptic terminals of vertebrate photoreceptors. Exp Eye Res. 2008; 87: 394-397.
    • (2008) Exp Eye Res , vol.87 , pp. 394-397
    • Chappell, R.L.1    Anastassov, I.2    Lugo, P.3    Ripps, H.4
  • 79
    • 7944227270 scopus 로고    scopus 로고
    • Localization of zinc transporter-3 (ZnT-3) in mouse retina
    • Redenti S, Chappell RL. Localization of zinc transporter-3 (ZnT-3) in mouse retina. Vision Res. 2004; 44: 3317-3321.
    • (2004) Vision Res , vol.44 , pp. 3317-3321
    • Redenti, S.1    Chappell, R.L.2
  • 80
    • 33750967658 scopus 로고    scopus 로고
    • Localization of ZnT7 and zinc ions in mouse retina: Immunohistochemistry and selenium autometallography
    • Wang X, Wang ZY, Gao HL, Danscher G, Huang L. Localization of ZnT7 and zinc ions in mouse retina: immunohistochemistry and selenium autometallography. Brain Res Bull. 2006; 71: 91-96.
    • (2006) Brain Res Bull , vol.71 , pp. 91-96
    • Wang, X.1    Wang, Z.Y.2    Gao, H.L.3    Danscher, G.4    Huang, L.5
  • 81
    • 34548489433 scopus 로고    scopus 로고
    • Müller cell zinc transporter-3 labeling suggests a role in outer retina zinc homeostasis
    • Redenti S, Chappell RL. Müller cell zinc transporter-3 labeling suggests a role in outer retina zinc homeostasis. Mol Med. 2007; 13: 376-379.
    • (2007) Mol Med , vol.13 , pp. 376-379
    • Redenti, S.1    Chappell, R.L.2
  • 82
    • 0035387949 scopus 로고    scopus 로고
    • Iron and other elements (Cu, Zn, Ca) contents in retina of rats during development and hereditary retinal degeneration
    • Sergeant C, Gouget B, Llabador Y, et al. Iron and other elements (Cu, Zn, Ca) contents in retina of rats during development and hereditary retinal degeneration. Nucl Instr Methods Phys Res B. 2001; 181: 533-538.
    • (2001) Nucl Instr Methods Phys Res B , vol.181 , pp. 533-538
    • Sergeant, C.1    Gouget, B.2    Llabador, Y.3
  • 83
    • 0036152131 scopus 로고    scopus 로고
    • Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats
    • Yefimova MG, Jeanny JC, Keller N, et al. Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats. Invest Ophthalmol Vis Sci. 2002; 43: 537-545.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 537-545
    • Yefimova, M.G.1    Jeanny, J.C.2    Keller, N.3
  • 84
    • 0036843101 scopus 로고    scopus 로고
    • Megalin and cubilin: The story of two multipurpose receptors unfolds
    • Verroust PJ, Christensen EI. Megalin and cubilin: the story of two multipurpose receptors unfolds. Nephrol Dial Transplant. 2002; 17: 1867-1871.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1867-1871
    • Verroust, P.J.1    Christensen, E.I.2
  • 85
    • 0035868910 scopus 로고    scopus 로고
    • Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption
    • Bösl MR, Stein V, Hübner C, et al. Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption. EMBO J. 2001; 20: 1289-1299.
    • (2001) EMBO J , vol.20 , pp. 1289-1299
    • Bösl, M.R.1    Stein, V.2    Hübner, C.3
  • 86
    • 0035951282 scopus 로고    scopus 로고
    • Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
    • Kornak U, Kasper D, Bösl MR, et al. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell. 2001; 104: 205-215.
    • (2001) Cell , vol.104 , pp. 205-215
    • Kornak, U.1    Kasper, D.2    Bösl, M.R.3
  • 87
    • 29244445480 scopus 로고    scopus 로고
    • Overlapping expression patterns of the multiligand endocytic receptors cubilin and megalin in the CNS, sensory organs and developing epithelia of the rodent embryo
    • Assémat E, Châtelet F, Chandellier J, et al. Overlapping expression patterns of the multiligand endocytic receptors cubilin and megalin in the CNS, sensory organs and developing epithelia of the rodent embryo. Gene Expr Patterns. 2005; 6: 69-78.
    • (2005) Gene Expr Patterns , vol.6 , pp. 69-78
    • Assémat, E.1    Châtelet, F.2    Chandellier, J.3
  • 88
    • 0038153196 scopus 로고    scopus 로고
    • Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules
    • Christensen EI, Devuyst O, Dom G, et al. Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules. Proc Natl Acad Sci U S A. 2003; 100: 8472-8477.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8472-8477
    • Christensen, E.I.1    Devuyst, O.2    Dom, G.3
  • 89
    • 48249088931 scopus 로고    scopus 로고
    • Selective degeneration of central photoreceptors after hyperbaric oxygen in normal and metallothionein-knockout mice
    • Nachman-Clewner M, Giblin FJ, Dorey CK, et al. Selective degeneration of central photoreceptors after hyperbaric oxygen in normal and metallothionein-knockout mice. Invest Ophthalmol Vis Sci. 2008; 49: 3207-3215.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 3207-3215
    • Nachman-Clewner, M.1    Giblin, F.J.2    Dorey, C.K.3
  • 91
    • 0032952723 scopus 로고    scopus 로고
    • Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression
    • Lee DK, Carrasco J, Hidalgo J, Andrews GK. Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression. Biochem J. 1999; 337: 59-65.
    • (1999) Biochem J , vol.337 , pp. 59-65
    • Lee, D.K.1    Carrasco, J.2    Hidalgo, J.3    Andrews, G.K.4
  • 92
    • 0038392877 scopus 로고    scopus 로고
    • Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury
    • Penkowa M, Giralt M, Lago N, et al. Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury. Exp Neurol. 2003; 181: 130-148.
    • (2003) Exp Neurol , vol.181 , pp. 130-148
    • Penkowa, M.1    Giralt, M.2    Lago, N.3
  • 93
    • 0035219629 scopus 로고    scopus 로고
    • Retinal pigment epithelium-immune system interactions: Cytokine production and cytokine-induced changes
    • Holtkamp GM, Kijlstra A, Peek R, de Vos AF. Retinal pigment epithelium-immune system interactions: cytokine production and cytokine-induced changes. Prog Retin Eye Res. 2001; 20: 29-48.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 29-48
    • Holtkamp, G.M.1    Kijlstra, A.2    Peek, R.3    de Vos, A.F.4
  • 94
    • 34249744612 scopus 로고    scopus 로고
    • Microglia activation in retinal degeneration
    • Langmann T. Microglia activation in retinal degeneration. J Leukoc Biol. 2007; 81: 1345-1351.
    • (2007) J Leukoc Biol , vol.81 , pp. 1345-1351
    • Langmann, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.