Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants

BMC Biotechnology

Volumn 9, Issue , 2009, Pages

  Nielsen, Troels T ^a,b   Jakobsson, Johan ^a   Rosenqvist, Nina ^a   Lundberg, Cecilia ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGES; DNA; GENE TRANSFER; GENES; INSULATION; INTERNET; NUCLEIC ACIDS; TRANSCRIPTION;

BOUNDARY ELEMENTS; CONTROL VECTORS; GENE TRANSFER VECTORS; IN-VIVO; INSERTIONAL MUTAGENESIS; LENTIVIRAL VECTORS; OPTIMAL DESIGNS; REVERSE TRANSCRIPTIONS; TARGET CELLS; TRANSDUCTION PROCESS; TRANSGENE; TRANSGENE EXPRESSIONS; TRANSGENE SILENCING; VIRAL DNAS;

VECTORS;

BETA GLOBIN; LENTIVIRUS VECTOR; VIRUS DNA;

ARTICLE; CONTROLLED STUDY; GENE CASSETTE; HUMAN; HUMAN CELL; INSULATOR ELEMENT; NONHUMAN; REVERSE TRANSCRIPTION; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS DNA CELL DNA INTERACTION; ANIMAL; BIOSYNTHESIS; CELL STRAIN K 562; CHICKEN; CHROMATIN; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE SILENCING; GENE VECTOR; GENETICS; LENTIVIRINAE; MOLECULAR CLONING; PLASMID;

ANIMALS; BETA-GLOBINS; CHICKENS; CHROMATIN; CLONING, MOLECULAR; DNA, VIRAL; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC VECTORS; HUMANS; INSULATOR ELEMENTS; K562 CELLS; LENTIVIRUS; MUTAGENESIS, INSERTIONAL; PLASMIDS; TRANSGENES; VIRUS INTEGRATION;

EID: 61949341072     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-9-13     Document Type: Article

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