The pattern of natural selection in somatic cancer mutations of human mtDNA

Journal of Human Genetics

Volumn 55, Issue 9, 2010, Pages 605-612

  Stafford, Pete ^a,b   Chen Quin, Estella B ^a  

^a KENNESAW STATE UNIVERSITY   (United States)

^b FLORIDA STATE UNIVERSITY   (United States)

Author keywords

cancer; germline mtDNA; mitochondria; selection; somatic mtDNA mutation

Indexed keywords

CYTOCHROME B; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ARTICLE; BOOTSTRAPPING; CARCINOGENESIS; GENE MUTATION; GERMLINE MICRONUCLEUS; MISSENSE MUTATION; MITOCHONDRION; NATURAL SELECTION; TUMOR CELL; TUMOR DIFFERENTIATION;

CLUSTER ANALYSIS; CYTOCHROMES B; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX IV; GERM-LINE MUTATION; HUMANS; MUTATION, MISSENSE; NADH DEHYDROGENASE; NEOPLASMS; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, TERTIARY; REGRESSION ANALYSIS; SELECTION, GENETIC;

EID: 77957314697     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1038/jhg.2010.76     Document Type: Article

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