-
1
-
-
0037041395
-
An extensive network of coupling among gene expression machines
-
DOI 10.1038/416499a
-
Maniatis T, Reed R. An extensive network of coupling among gene expression machines. Nature 2002; 416:499-506. (Pubitemid 34288845)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 499-506
-
-
Maniatis, T.1
Reed, R.2
-
3
-
-
33745394130
-
Alternative splicing and RNA selection pressure - Evolutionary consequences for eukaryotic genomes
-
Xing Y, Lee C. Alternative splicing and RNA selection pressure - evolutionary consequences for eukaryotic genomes. Nat Rev Genet 2006; 7:499-509.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 499-509
-
-
Xing, Y.1
Lee, C.2
-
5
-
-
35548940665
-
Neuronal regulation of alternative pre-mRNA splicing
-
Li Q, Lee JA, Black DL. Neuronal regulation of alternative pre-mRNA splicing. Nat Rev Neurosci 2007; 8:819-31.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 819-831
-
-
Li, Q.1
Lee, J.A.2
Black, D.L.3
-
6
-
-
0028307171
-
Split genes and RNA splicing
-
Sharp PA. Split genes and RNA splicing. Cell 1994; 77:805-15.
-
(1994)
Cell
, vol.77
, pp. 805-815
-
-
Sharp, P.A.1
-
7
-
-
55249093247
-
Structure and function of the Pre-mRNA splicing machine
-
Sperling J, Azubel M, Sperling R. Structure and function of the Pre-mRNA splicing machine. Structure 2008; 16:1605-15.
-
(2008)
Structure
, vol.16
, pp. 1605-1615
-
-
Sperling, J.1
Azubel, M.2
Sperling, R.3
-
8
-
-
26244462463
-
Alternative splicing - When two's a crowd
-
Smith CW. Alternative splicing - when two's a crowd. Cell 2005; 123:1-3.
-
(2005)
Cell
, vol.123
, pp. 1-3
-
-
Smith, C.W.1
-
9
-
-
19344363974
-
Promoter usage and alternative splicing
-
Kornblihtt AR. Promoter usage and alternative splicing. Curr Opin Cell Biol 2005; 17:262-8.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 262-268
-
-
Kornblihtt, A.R.1
-
12
-
-
42449105386
-
Nuclear organization and splicing control
-
Carmo-Fonseca M, Carvalho C. Nuclear organization and splicing control. Adv Exp Med Biol 2007; 623:1-13.
-
(2007)
Adv Exp Med Biol
, vol.623
, pp. 1-13
-
-
Carmo-Fonseca, M.1
Carvalho, C.2
-
13
-
-
63149192174
-
Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing
-
Schor IE, Rascovan N, Pelisch F, Allo M, Kornblihtt AR. Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing. Proc Natl Acad Sci USA 2009; 106:4325-30.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4325-4330
-
-
Schor, I.E.1
Rascovan, N.2
Pelisch, F.3
Allo, M.4
Kornblihtt, A.R.5
-
14
-
-
38349127601
-
Combinatorial control of exon recognition
-
Hertel KJ. Combinatorial control of exon recognition. J Biol Chem 2008; 283:1211-5.
-
(2008)
J Biol Chem
, vol.283
, pp. 1211-1215
-
-
Hertel, K.J.1
-
15
-
-
12344250822
-
Function of alternative splicing
-
Stamm S, Ben-Ari S, Rafalska I, Tang Y, Zhang Z, Toiber D, et al. Function of alternative splicing. Gene 2005; 344:1-20.
-
(2005)
Gene
, vol.344
, pp. 1-20
-
-
Stamm, S.1
Ben-Ari, S.2
Rafalska, I.3
Tang, Y.4
Zhang, Z.5
Toiber, D.6
-
16
-
-
56749098074
-
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
-
Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 2008; 40:1413-5.
-
(2008)
Nat Genet
, vol.40
, pp. 1413-1415
-
-
Pan, Q.1
Shai, O.2
Lee, L.J.3
Frey, B.J.4
Blencowe, B.J.5
-
17
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
DOI 10.1038/nature07509, PII NATURE07509
-
Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, et al. Alternative isoform regulation in human tissue transcriptomes. Nature 2008; 456:470-6. (Pubitemid 352759009)
-
(2008)
Nature
, vol.456
, Issue.7221
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
Kingsmore, S.F.7
Schroth, G.P.8
Burge, C.B.9
-
18
-
-
26244435561
-
Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures
-
Graveley BR. Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures. Cell 2005; 123:65-73.
-
(2005)
Cell
, vol.123
, pp. 65-73
-
-
Graveley, B.R.1
-
20
-
-
56649117675
-
The assembly of a spliceosomal small nuclear ribonucleoprotein particle
-
Patel SB, Bellini M. The assembly of a spliceosomal small nuclear ribonucleoprotein particle. Nucleic Acids Res 2008; 36:6482-93.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6482-6493
-
-
Patel, S.B.1
Bellini, M.2
-
21
-
-
0344198459
-
The Spliceosome: The Most Complex Macromolecular Machine in the Cell?
-
Nilsen TW. The spliceosome: the most complex macromolecular machine in the cell? Bioessays 2003; 25:1147-9.
-
(2003)
Bioessays
, vol.25
, pp. 1147-1149
-
-
Nilsen, T.W.1
-
22
-
-
0042671357
-
Pre-mRNA splicing: Awash in a sea of proteins
-
Jurica MS, Moore MJ. Pre-mRNA splicing: awash in a sea of proteins. Mol Cell 2003; 12:5-14.
-
(2003)
Mol Cell
, vol.12
, pp. 5-14
-
-
Jurica, M.S.1
Moore, M.J.2
-
23
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl MC, Will CL, Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009; 136:701-18.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
24
-
-
63649099704
-
Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution
-
Pomeranz Krummel DA, Oubridge C, Leung AK, Li J, Nagai K. Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution. Nature 2009; 458:475-80.
-
(2009)
Nature
, vol.458
, pp. 475-480
-
-
Pomeranz Krummel, D.A.1
Oubridge, C.2
Leung, A.K.3
Li, J.4
Nagai, K.5
-
25
-
-
0036829065
-
U1 snRNA associates with TFIIH and regulates transcriptional initiation
-
Kwek KY, Murphy S, Furger A, Thomas B, O'Gorman W, Kimura H, et al. U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat Struct Biol 2002; 9:800-5. (Pubitemid 35257777)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.11
, pp. 800-805
-
-
Kwek, K.Y.1
Murphy, S.2
Furger, A.3
Thomas, B.4
O'Gorman, W.5
Kimura, H.6
Proudfoot, N.J.7
Akoulitchev, A.8
-
26
-
-
0030024350
-
Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro
-
Lutz CS, Murthy KG, Schek N, O'Connor JP, Manley JL, Alwine JC. Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev 1996; 10:325-37. (Pubitemid 26058965)
-
(1996)
Genes and Development
, vol.10
, Issue.3
, pp. 325-337
-
-
Lutz, C.S.1
Murthy, K.G.K.2
Schek, N.3
O'Connor, J.P.4
Manley, J.L.5
Alwine, J.C.6
-
27
-
-
0031610367
-
U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase
-
Gunderson SI, Polycarpou-Schwarz M, Mattaj IW. U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1998; 1:255-64. (Pubitemid 128378666)
-
(1998)
Molecular Cell
, vol.1
, Issue.2
, pp. 255-264
-
-
Gunderson, S.I.1
Polycarpou-Schwarz, M.2
Mattaj, I.W.3
-
28
-
-
0038492463
-
Inhibiting expression of specific genes in mammalian cells with 5′ end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA
-
Fortes P, Cuevas Y, Guan F, Liu P, Pentlicky S, Jung SP, et al. Inhibiting expression of specific genes in mammalian cells with 5′ end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA. Proc Natl Acad Sci USA 2003; 100:8264-9.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8264-8269
-
-
Fortes, P.1
Cuevas, Y.2
Guan, F.3
Liu, P.4
Pentlicky, S.5
Jung, S.P.6
-
29
-
-
0020773732
-
The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro
-
Mount SM, Pettersson I, Hinterberger M, Karmas A, Steitz JA. The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro. Cell 1983; 33:509-18.
-
(1983)
Cell
, vol.33
, pp. 509-518
-
-
Mount, S.M.1
Pettersson, I.2
Hinterberger, M.3
Karmas, A.4
Steitz, J.A.5
-
30
-
-
0018872571
-
Are snRNPs involved in splicing?
-
Lerner MR, Boyle JA, Mount SM, Wolin SL, Steitz JA. Are snRNPs involved in splicing? Nature 1980; 283:220-4.
-
(1980)
Nature
, vol.283
, pp. 220-224
-
-
Lerner, M.R.1
Boyle, J.A.2
Mount, S.M.3
Wolin, S.L.4
Steitz, J.A.5
-
32
-
-
0022550119
-
A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation
-
Zhuang Y, Weiner AM. A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation. Cell 1986; 46:827-35.
-
(1986)
Cell
, vol.46
, pp. 827-835
-
-
Zhuang, Y.1
Weiner, A.M.2
-
33
-
-
0024062611
-
A U1 snRNA:premRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site
-
Seraphin B, Kretzner L, Rosbash M. A U1 snRNA:premRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site. EMBO J 1988; 7:2533-8.
-
(1988)
EMBO J
, vol.7
, pp. 2533-2538
-
-
Seraphin, B.1
Kretzner, L.2
Rosbash, M.3
-
34
-
-
0024100924
-
5′ splice site selection in yeast: Genetic alterations in base-pairing with U1 reveal additional requirements
-
Siliciano PG, Guthrie C. 5′ splice site selection in yeast: genetic alterations in base-pairing with U1 reveal additional requirements. Genes Dev 1988; 2:1258-67.
-
(1988)
Genes Dev
, vol.2
, pp. 1258-1267
-
-
Siliciano, P.G.1
Guthrie, C.2
-
35
-
-
0035031935
-
The sequence complementarity between HIV-1 5′ splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA
-
Kammler S, Leurs C, Freund M, Krummheuer J, Seidel K, Tange TO, et al. The sequence complementarity between HIV-1 5′ splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA. Rna 2001; 7:421-34.
-
(2001)
Rna
, vol.7
, pp. 421-434
-
-
Kammler, S.1
Leurs, C.2
Freund, M.3
Krummheuer, J.4
Seidel, K.5
Tange, T.O.6
-
36
-
-
0031921640
-
Statistical features of human exons and their flanking regions
-
Zhang MQ. Statistical features of human exons and their flanking regions. Hum Mol Genet 1998; 7:919-32.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 919-932
-
-
Zhang, M.Q.1
-
37
-
-
33748581324
-
Comprehensive splice-site analysis using comparative genomics
-
Sheth N, Roca X, Hastings ML, Roeder T, Krainer AR, Sachidanandam R. Comprehensive splice-site analysis using comparative genomics. Nucleic Acids Res 2006; 34:3955-67.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3955-3967
-
-
Sheth, N.1
Roca, X.2
Hastings, M.L.3
Roeder, T.4
Krainer, A.R.5
Sachidanandam, R.6
-
38
-
-
0035165586
-
SpliceDB: Database of canonical and non-canonical mammalian splice sites
-
Burset M, Seledtsov IA, Solovyev VV. SpliceDB: database of canonical and non-canonical mammalian splice sites. Nucleic Acids Res 2001; 29:255-9.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 255-259
-
-
Burset, M.1
Seledtsov, I.A.2
Solovyev, V.V.3
-
39
-
-
33748127132
-
U1-like snRNAs lacking complementarity to canonical 5′ splice sites
-
DOI 10.1261/rna.26506
-
Kyriakopoulou C, Larsson P, Liu L, Schuster J, Soderbom F, Kirsebom LA, et al. U1-like snRNAs lacking complementarity to canonical 5′ splice sites. Rna 2006; 12:1603-11. (Pubitemid 44316024)
-
(2006)
RNA
, vol.12
, Issue.9
, pp. 1603-1611
-
-
Kyriakopoulou, C.1
Larsson, P.2
Liu, L.3
Schuster, J.4
Soderbom, F.5
Kirsebom, L.A.6
Virtanen, A.7
-
40
-
-
0026263756
-
An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway
-
Michaud S, Reed R. An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway. Genes Dev 1991; 5:2534-46. (Pubitemid 21905937)
-
(1991)
Genes and Development
, vol.5
, Issue.12 PART B
, pp. 2534-2546
-
-
Michaud, S.1
Reed, R.2
-
41
-
-
0024325159
-
Identification of functional U1 snRNA-Pre-mRNA complexes committed to spliceosome assembly and splicing
-
DOI 10.1016/0092-8674(89)90296-1
-
Seraphin B, Rosbash M. Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing. Cell 1989; 59:349-58. (Pubitemid 19264379)
-
(1989)
Cell
, vol.59
, Issue.2
, pp. 349-358
-
-
Seraphin, B.1
Rosbash, M.2
-
42
-
-
25144471268
-
Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5′ splice site recognition
-
DOI 10.1093/nar/gki824
-
Freund M, Hicks MJ, Konermann C, Otte M, Hertel KJ, Schaal H. Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognition. Nucleic Acids Res 2005; 33:5112-9. (Pubitemid 41487819)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.16
, pp. 5112-5119
-
-
Freund, M.1
Hicks, M.J.2
Konermann, C.3
Otte, M.4
Hertel, K.J.5
Schaal, H.6
-
43
-
-
0033010430
-
An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p
-
DOI 10.1016/S1097-2765(00)80174-4
-
Staley JP, Guthrie C. An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p. Mol Cell 1999; 3:55-64. (Pubitemid 29292477)
-
(1999)
Molecular Cell
, vol.3
, Issue.1
, pp. 55-64
-
-
Staley, J.P.1
Guthrie, C.2
-
44
-
-
59649083526
-
Recognition of atypical 5′ splice sites by shifted base-pairing to U1 snRNA
-
Roca X, Krainer AR. Recognition of atypical 5′ splice sites by shifted base-pairing to U1 snRNA. Nat Struct Mol Biol 2009; 16:176-82.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 176-182
-
-
Roca, X.1
Krainer, A.R.2
-
46
-
-
0037121924
-
The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5′ splice sites
-
DOI 10.1093/emboj/cdf668
-
Forch P, Puig O, Martinez C, Seraphin B, Valcarcel J. The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5′ splice sites. EMBO J 2002; 21:6882-92. (Pubitemid 36014560)
-
(2002)
EMBO Journal
, vol.21
, Issue.24
, pp. 6882-6892
-
-
Forch, P.1
Puig, O.2
Martinez, C.3
Seraphin, B.4
Valcarcel, J.5
-
47
-
-
0037026523
-
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
-
DOI 10.1038/nature00947
-
Du H, Rosbash M. The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing. Nature 2002; 419:86-90. (Pubitemid 34987875)
-
(2002)
Nature
, vol.419
, Issue.6902
, pp. 86-90
-
-
Du, H.1
Rosbash, M.2
-
48
-
-
0033053502
-
The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5′ splice site
-
Reyes JL, Gustafson EH, Luo HR, Moore MJ, Konarska MM. The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5′ splice site. Rna 1999; 5:167-79.
-
(1999)
Rna
, vol.5
, pp. 167-179
-
-
Reyes, J.L.1
Gustafson, E.H.2
Luo, H.R.3
Moore, M.J.4
Konarska, M.M.5
-
49
-
-
1142310938
-
Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock
-
DOI 10.1038/nature02288
-
Shin C, Feng Y, Manley JL. Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. Nature 2004; 427:553-8. (Pubitemid 38209114)
-
(2004)
Nature
, vol.427
, Issue.6974
, pp. 553-558
-
-
Shin, C.1
Feng, Y.2
Manley, J.L.3
-
50
-
-
0030061154
-
SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element
-
McNally LM, McNally MT. SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element. J Virol 1996; 70:1163-72.
-
(1996)
J Virol
, vol.70
, pp. 1163-1172
-
-
McNally, L.M.1
McNally, M.T.2
-
51
-
-
0032981016
-
U1 small nuclear ribonucleoprotein and splicing inhibition by the rous sarcoma virus negative regulator of splicing element
-
McNally LM, McNally MT. U1 small nuclear ribonucleoprotein and splicing inhibition by the rous sarcoma virus negative regulator of splicing element. J Virol 1999; 73:2385-93.
-
(1999)
J Virol
, vol.73
, pp. 2385-2393
-
-
McNally, L.M.1
McNally, M.T.2
-
52
-
-
4644293327
-
Two regions promote U11 small nuclear ribonucleoprotein particle binding to a retroviral splicing inhibitor element (negative regulator of splicing)
-
McNally LM, Yee L, McNally MT. Two regions promote U11 small nuclear ribonucleoprotein particle binding to a retroviral splicing inhibitor element (negative regulator of splicing). J Biol Chem 2004; 279:38201-8.
-
(2004)
J Biol Chem
, vol.279
, pp. 38201-38208
-
-
McNally, L.M.1
Yee, L.2
McNally, M.T.3
-
53
-
-
0034644743
-
A cellular protein, hnRNP H, binds to the negative regulator of splicing element from Rous sarcoma virus
-
Fogel BL, McNally MT. A cellular protein, hnRNP H, binds to the negative regulator of splicing element from Rous sarcoma virus. J Biol Chem 2000; 275:32371-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 32371-32378
-
-
Fogel, B.L.1
McNally, M.T.2
-
54
-
-
0036464505
-
Efficient polyadenylation of Rous sarcoma virus RNA requires the negative regulator of splicing element
-
Fogel BL, McNally LM, McNally MT. Efficient polyadenylation of Rous sarcoma virus RNA requires the negative regulator of splicing element. Nucleic Acids Res 2002; 30:810-7.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 810-817
-
-
Fogel, B.L.1
McNally, L.M.2
McNally, M.T.3
-
55
-
-
33644856084
-
Exon tethering in transcription by RNA polymerase II
-
DOI 10.1016/j.molcel.2006.01.032, PII S1097276506000803
-
Dye MJ, Gromak N, Proudfoot NJ. Exon tethering in transcription by RNA polymerase II. Mol Cell 2006; 21:849-59. (Pubitemid 43376134)
-
(2006)
Molecular Cell
, vol.21
, Issue.6
, pp. 849-859
-
-
Dye, M.J.1
Gromak, N.2
Proudfoot, N.J.3
-
56
-
-
0031867840
-
An RNA splicing enhancer- Like sequence is a component of a splicing inhibitor element from Rous sarcoma virus
-
McNally LM, McNally MT. An RNA splicing enhancer- like sequence is a component of a splicing inhibitor element from Rous sarcoma virus. Mol Cell Biol 1998; 18:3103-11.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3103-3111
-
-
McNally, L.M.1
McNally, M.T.2
-
57
-
-
33746855164
-
Defective splicing, disease and therapy: Searching for master checkpoints in exon definition
-
Buratti E, Baralle M, Baralle FE. Defective splicing, disease and therapy: searching for master checkpoints in exon definition. Nucleic Acids Res 2006; 34:3494-510.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3494-3510
-
-
Buratti, E.1
Baralle, M.2
Baralle, F.E.3
-
58
-
-
33746354005
-
NF1 mRNA biogenesis: Effect of the genomic milieu in splicing regulation of the NF1 exon 37 region
-
DOI 10.1016/j.febslet.2006.07.018, PII S0014579306008489
-
Baralle M, Skoko N, Knezevich A, De Conti L, Motti D, Bhuvanagiri M, et al. NF1 mRNA biogenesis: Effect of the genomic milieu in splicing regulation of the NF1 exon 37 region. FEBS Lett 2006; 580:4449-56. (Pubitemid 44118266)
-
(2006)
FEBS Letters
, vol.580
, Issue.18
, pp. 4449-4456
-
-
Baralle, M.1
Skoko, N.2
Knezevich, A.3
De Conti, L.4
Motti, D.5
Bhuvanagiri, M.6
Baralle, D.7
Buratti, E.8
Baralle, F.E.9
-
59
-
-
76149138842
-
Alternative splicing: Role of pseudoexons in human disease and potential therapeutic strategies
-
Dhir A, Buratti E. Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies. Febs J 2010; 277:841-55.
-
(2010)
Febs J
, vol.277
, pp. 841-855
-
-
Dhir, A.1
Buratti, E.2
-
60
-
-
0033846543
-
Multiple splicing defects in an intronic false exon
-
DOI 10.1128/MCB.20.17.6414-6425.2000
-
Sun H, Chasin LA. Multiple splicing defects in an intronic false exon. Mol Cell Biol 2000; 20:6414-25. (Pubitemid 30650229)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.17
, pp. 6414-6425
-
-
Sun, H.1
Chasin, L.A.2
-
61
-
-
2642513654
-
Silencer elements as possible inhibitors of pseudoexon splicing
-
DOI 10.1093/nar/gkh341
-
Sironi M, Menozzi G, Riva L, Cagliani R, Comi GP, Bresolin N, et al. Silencer elements as possible inhibitors of pseudoexon splicing. Nucleic Acids Res 2004; 32:1783-91. (Pubitemid 38832723)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.5
, pp. 1783-1791
-
-
Sironi, M.1
Menozzi, G.2
Riva, L.3
Cagliani, R.4
Comi, G.P.5
Bresolin, N.6
Giorda, R.7
Pozzoli, U.8
-
62
-
-
2642525438
-
Computational definition of sequence motifs governing constitutive exon splicing
-
Zhang XH, Chasin LA. Computational definition of sequence motifs governing constitutive exon splicing. Genes Dev 2004; 18:1241-50.
-
(2004)
Genes Dev
, vol.18
, pp. 1241-1250
-
-
Zhang, X.H.1
Chasin, L.A.2
-
63
-
-
0033811608
-
Human genomic sequences that inhibit splicing
-
Fairbrother WG, Chasin LA. Human genomic sequences that inhibit splicing. Mol Cell Biol 2000; 20:6816-25.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6816-6825
-
-
Fairbrother, W.G.1
Chasin, L.A.2
-
64
-
-
22344439658
-
Dichotomous splicing signals in exon flanks
-
Zhang XH, Leslie CS, Chasin LA. Dichotomous splicing signals in exon flanks. Genome Res 2005; 15:768-79.
-
(2005)
Genome Res
, vol.15
, pp. 768-779
-
-
Zhang, X.H.1
Leslie, C.S.2
Chasin, L.A.3
-
65
-
-
56849094416
-
Polypyrimidine tract binding protein regulates alternative splicing of an aberrant pseudoexon in NF1
-
Raponi M, Buratti E, Llorian M, Stuani C, Smith CW, Baralle D. Polypyrimidine tract binding protein regulates alternative splicing of an aberrant pseudoexon in NF1. Febs J 2008; 275:6101-8.
-
(2008)
Febs J
, vol.275
, pp. 6101-6108
-
-
Raponi, M.1
Buratti, E.2
Llorian, M.3
Stuani, C.4
Smith, C.W.5
Baralle, D.6
-
66
-
-
58149094780
-
A nonsense exon in the Tpm1 gene is silenced by hnRNP H and F
-
Coles JL, Hallegger M, Smith CW. A nonsense exon in the Tpm1 gene is silenced by hnRNP H and F. Rna 2009; 15:33-43.
-
(2009)
Rna
, vol.15
, pp. 33-43
-
-
Coles, J.L.1
Hallegger, M.2
Smith, C.W.3
-
67
-
-
0036544858
-
A new type of mutation causes a splicing defect in ATM
-
Pagani F, Buratti E, Stuani C, Bendix R, Dork T, Baralle FE. A new type of mutation causes a splicing defect in ATM. Nat Genet 2002; 30:426-9.
-
(2002)
Nat Genet
, vol.30
, pp. 426-429
-
-
Pagani, F.1
Buratti, E.2
Stuani, C.3
Bendix, R.4
Dork, T.5
Baralle, F.E.6
-
68
-
-
34547850638
-
RNA structure is a key regulatory element in pathology ATM and CFTR pseudoexon inclusion events
-
DOI 10.1093/nar/gkm447
-
Buratti E, Dhir A, Lewandowska MA, Baralle FE. RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events. Nucleic Acids Res 2007; 35:4369-83. (Pubitemid 47248459)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.13
, pp. 4369-4383
-
-
Buratti, E.1
Dhir, A.2
Lewandowska, M.A.3
Baralle, F.E.4
-
70
-
-
34948821069
-
Pre-spliceosomal binding of U1 small nuclear ribonucleoprotein (RNP) and heterogenous nuclear RNP E1 is associated with suppression of a growth hormone receptor pseudoexon
-
DOI 10.1210/me.2007-0038
-
Akker SA, Misra S, Aslam S, Morgan EL, Smith PJ, Khoo B, et al. Pre-spliceosomal binding of U1 small nuclear ribonucleoprotein (RNP) and heterogenous nuclear RNP E1 is associated with suppression of a growth hormone receptor pseudoexon. Mol Endocrinol 2007; 21:2529-40. (Pubitemid 47529363)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.10
, pp. 2529-2540
-
-
Akker, S.A.1
Misra, S.2
Aslam, S.3
Morgan, E.L.4
Smith, P.J.5
Khoo, B.6
Chew, S.L.7
-
71
-
-
33745501015
-
General and Specific Functions of Exonic Splicing Silencers in Splicing Control
-
DOI 10.1016/j.molcel.2006.05.018, PII S1097276506003339
-
Wang Z, Xiao X, Van Nostrand E, Burge CB. General and specific functions of exonic splicing silencers in splicing control. Mol Cell 2006; 23:61-70. (Pubitemid 43963442)
-
(2006)
Molecular Cell
, vol.23
, Issue.1
, pp. 61-70
-
-
Wang, Z.1
Xiao, X.2
Van Nostrand, E.3
Burge, C.B.4
-
72
-
-
10944256767
-
Systematic identification and analysis of exonic splicing silencers
-
DOI 10.1016/j.cell.2004.11.010, PII S0092867404010566
-
Wang Z, Rolish ME, Yeo G, Tung V, Mawson M, Burge CB. Systematic identification and analysis of exonic splicing silencers. Cell 2004; 119:831-45. (Pubitemid 40017689)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 831-845
-
-
Wang, Z.1
Rolish, M.E.2
Yeo, G.3
Tung, V.4
Mawson, M.5
Burge, C.B.6
-
73
-
-
26944453614
-
Splicing in action: Assessing disease causing sequence changes
-
DOI 10.1136/jmg.2004.029538
-
Baralle D, Baralle M. Splicing in action: assessing disease causing sequence changes. J Med Genet 2005; 42:737-48. (Pubitemid 41475248)
-
(2005)
Journal of Medical Genetics
, vol.42
, Issue.10
, pp. 737-748
-
-
Baralle, D.1
Baralle, M.2
-
76
-
-
68249121529
-
Missed threads. The impact of pre-mRNA splicing defects on clinical practice
-
Baralle D, Lucassen A, Buratti E. Missed threads. The impact of pre-mRNA splicing defects on clinical practice. EMBO Rep 2009; 10:810-6.
-
(2009)
EMBO Rep
, vol.10
, pp. 810-816
-
-
Baralle, D.1
Lucassen, A.2
Buratti, E.3
-
77
-
-
55549143293
-
The emerging role of splicing factors in cancer
-
Grosso AR, Martins S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008; 9:1087-93.
-
(2008)
EMBO Rep
, vol.9
, pp. 1087-1093
-
-
Grosso, A.R.1
Martins, S.2
Carmo-Fonseca, M.3
-
79
-
-
73949128867
-
The pathobiology of splicing
-
Ward AJ, Cooper TA. The pathobiology of splicing. J Pathol 2009; 220:152-63.
-
(2009)
J Pathol
, vol.220
, pp. 152-163
-
-
Ward, A.J.1
Cooper, T.A.2
-
80
-
-
76149097154
-
Alternative splicing: Good and bad effects of translationally silent substitutions
-
Raponi M, Baralle D. Alternative splicing: good and bad effects of translationally silent substitutions. Febs J 2010.
-
(2010)
Febs J
-
-
Raponi, M.1
Baralle, D.2
-
81
-
-
76149126823
-
Alternative splicing in the regulation of HIV-1 multiplication - A target for therapeutic action
-
Tazi J, Bakkour N, Aboufirassi A, Branlant C. Alternative splicing in the regulation of HIV-1 multiplication -a target for therapeutic action. FEBS J 2009.
-
(2009)
FEBS J
-
-
Tazi, J.1
Bakkour, N.2
Aboufirassi, A.3
Branlant, C.4
-
82
-
-
27144442421
-
Making antisense of splicing
-
Garcia-Blanco MA. Making antisense of splicing. Curr Opin Mol Ther 2005; 7:476-82.
-
(2005)
Curr Opin Mol Ther
, vol.7
, pp. 476-482
-
-
Garcia-Blanco, M.A.1
-
83
-
-
0037313165
-
Correction of disease-associated exon skipping by synthetic exon-specific activators
-
DOI 10.1038/nsb887
-
Cartegni L, Krainer AR. Correction of disease-associated exon skipping by synthetic exon-specific activators. Nat Struct Biol 2003; 10:120-5. (Pubitemid 36177092)
-
(2003)
Nature Structural Biology
, vol.10
, Issue.2
, pp. 120-125
-
-
Cartegni, L.1
Krainer, A.R.2
-
84
-
-
0037388256
-
Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts
-
DOI 10.1073/pnas.0633863100
-
Skordis LA, Dunckley MG, Yue B, Eperon IC, Muntoni F. Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts. Proc Natl Acad Sci USA 2003; 100:4114-9. (Pubitemid 36418166)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4114-4119
-
-
Skordis, L.A.1
Dunckley, M.G.2
Yue, B.3
Eperon, I.C.4
Muntoni, F.5
-
85
-
-
0038265106
-
Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better?
-
Buratti E, Baralle FE, Pagani F. Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better? Trends Mol Med 2003; 9:229-32.
-
(2003)
Trends Mol Med
, vol.9
, pp. 229-232
-
-
Buratti, E.1
Baralle, F.E.2
Pagani, F.3
-
86
-
-
0036137663
-
Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing
-
Liu X, Jiang Q, Mansfield SG, Puttaraju M, Zhang Y, Zhou W, et al. Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing. Nat Biotechnol 2002; 20:47-52.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 47-52
-
-
Liu, X.1
Jiang, Q.2
Mansfield, S.G.3
Puttaraju, M.4
Zhang, Y.5
Zhou, W.6
-
87
-
-
0032574744
-
Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs
-
Gorman L, Suter D, Emerick V, Schumperli D, Kole R. Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs. Proc Natl Acad Sci USA 1998; 95:4929-34.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4929-4934
-
-
Gorman, L.1
Suter, D.2
Emerick, V.3
Schumperli, D.4
Kole, R.5
-
88
-
-
10044240371
-
Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping
-
Goyenvalle A, Vulin A, Fougerousse F, Leturcq F, Kaplan JC, Garcia L, et al. Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping. Science 2004; 306:1796-9.
-
(2004)
Science
, vol.306
, pp. 1796-1799
-
-
Goyenvalle, A.1
Vulin, A.2
Fougerousse, F.3
Leturcq, F.4
Kaplan, J.C.5
Garcia, L.6
-
89
-
-
0027191972
-
U1 small nuclear RNAs with altered specificity can be stably expressed in mammalian cells and promote permanent changes in pre-mRNA splicing
-
Cohen JB, Broz SD, Levinson AD. U1 small nuclear RNAs with altered specificity can be stably expressed in mammalian cells and promote permanent changes in pre-mRNA splicing. Mol Cell Biol 1993; 13:2666-76.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 2666-2676
-
-
Cohen, J.B.1
Broz, S.D.2
Levinson, A.D.3
-
90
-
-
0037337527
-
Identification of a mutation that perturbs NF1 gene splicing using genomic DNA samples and a minigene assay [6]
-
Baralle M, Baralle D, De Conti L, Mattocks C, Whittaker J, Knezevich A, et al. Identification of a mutation that perturbs NF1, a gene splicing using genomic DNA samples and a minigene assay. J Med Genet 2003; 40:220-2. (Pubitemid 36315397)
-
(2003)
Journal of Medical Genetics
, vol.40
, Issue.3
, pp. 220-222
-
-
Baralle, M.1
Baralle, D.2
De Conti, L.3
Mattocks, C.4
Whittaker, J.5
Knezevich, A.6
Ffrench-Constant, C.7
Baralle, F.E.8
-
91
-
-
4143077123
-
TCIRG1-dependent recessive osteopetrosis: Mutation analysis, functional identification of the splicing defects, and in vitro rescue by U1 snRNA
-
DOI 10.1002/humu.20076
-
Susani L, Pangrazio A, Sobacchi C, Taranta A, Mortier G, Savarirayan R, et al. TCIRG1-dependent recessive osteopetrosis: mutation analysis, functional identification of the splicing defects, and in vitro rescue by U1 snRNA. Hum Mutat 2004; 24:225-35. (Pubitemid 39095599)
-
(2004)
Human Mutation
, vol.24
, Issue.3
, pp. 225-235
-
-
Susani, L.1
Pangrazio, A.2
Sobacchi, C.3
Taranta, A.4
Mortier, G.5
Savarirayan, R.6
Villa, A.7
Orchard, P.8
Vezzoni, P.9
Albertini, A.10
Frattini, A.11
Pagani, F.12
-
92
-
-
41949088960
-
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency
-
Pinotti M, Rizzotto L, Balestra D, Lewandowska MA, Cavallari N, Marchetti G, et al. U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency. Blood 2008; 111:2681-4.
-
(2008)
Blood
, vol.111
, pp. 2681-2684
-
-
Pinotti, M.1
Rizzotto, L.2
Balestra, D.3
Lewandowska, M.A.4
Cavallari, N.5
Marchetti, G.6
-
93
-
-
59749104368
-
Therapeutic strategy to rescue mutation-induced exon skipping in rhodopsin by adaptation of U1 snRNA
-
Tanner G, Glaus E, Barthelmes D, Ader M, Fleischhauer J, Pagani F, et al. Therapeutic strategy to rescue mutation-induced exon skipping in rhodopsin by adaptation of U1 snRNA. Hum Mutat 2009; 30:255-63.
-
(2009)
Hum Mutat
, vol.30
, pp. 255-263
-
-
Tanner, G.1
Glaus, E.2
Barthelmes, D.3
Ader, M.4
Fleischhauer, J.5
Pagani, F.6
-
94
-
-
0034680771
-
Restoration of correct splicing of thalassemic beta-globin pre-mRNA by modified U1 snRNAs
-
Gorman L, Mercatante DR, Kole R. Restoration of correct splicing of thalassemic beta-globin pre-mRNA by modified U1 snRNAs. J Biol Chem 2000; 275:35914-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 35914-35919
-
-
Gorman, L.1
Mercatante, D.R.2
Kole, R.3
-
96
-
-
0028072388
-
SR proteins can compensate for the loss of U1 snRNP functions in vitro
-
Tarn WY, Steitz JA. SR proteins can compensate for the loss of U1 snRNP functions in vitro. Genes Dev 1994; 8:2704-17.
-
(1994)
Genes Dev
, vol.8
, pp. 2704-2717
-
-
Tarn, W.Y.1
Steitz, J.A.2
-
97
-
-
0028034324
-
Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP
-
Crispino JD, Blencowe BJ, Sharp PA. Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP. Science 1994; 265:1866-9.
-
(1994)
Science
, vol.265
, pp. 1866-1869
-
-
Crispino, J.D.1
Blencowe, B.J.2
Sharp, P.A.3
-
99
-
-
0029949594
-
Cis-acting elements distinct from the 5' splice site promote U1-independent pre-mRNA splicing
-
Crispino JD, Mermoud JE, Lamond AI, Sharp PA. Cis-acting elements distinct from the 5' splice site promote U1-independent pre-mRNA splicing. Rna 1996; 2:664-73.
-
(1996)
Rna
, vol.2
, pp. 664-673
-
-
Crispino, J.D.1
Mermoud, J.E.2
Lamond, A.I.3
Sharp, P.A.4
-
100
-
-
62149129582
-
Low U1 snRNP dependence at the NF1 exon 29 donor splice site
-
Raponi M, Buratti E, Dassie E, Upadhyaya M, Baralle D. Low U1 snRNP dependence at the NF1 exon 29 donor splice site. Febs J 2009; 276:2060-73.
-
(2009)
Febs J
, vol.276
, pp. 2060-2073
-
-
Raponi, M.1
Buratti, E.2
Dassie, E.3
Upadhyaya, M.4
Baralle, D.5
-
101
-
-
64549089569
-
U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing
-
Fukumura K, Taniguchi I, Sakamoto H, Ohno M, Inoue K. U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing. Nucleic Acids Res 2009; 37:1907-14.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1907-1914
-
-
Fukumura, K.1
Taniguchi, I.2
Sakamoto, H.3
Ohno, M.4
Inoue, K.5
-
102
-
-
70349609214
-
Role and mechanism of U1-independent pre-mRNA splicing in the regulation of alternative splicing
-
Fukumura K, Inoue K. Role and mechanism of U1-independent pre-mRNA splicing in the regulation of alternative splicing. RNA Biol 2009; 6:395-8.
-
(2009)
RNA Biol
, vol.6
, pp. 395-398
-
-
Fukumura, K.1
Inoue, K.2
|