Polypyrimidine tract binding protein regulates alternative splicing of an aberrant pseudoexon in NF1

FEBS Journal

Volumn 275, Issue 24, 2008, Pages 6101-6108

  Raponi, Michela ^a   Buratti, Emanuele ^b   Llorian, Miriam ^c   Stuani, Cristiana ^b   Smith, Christopher W J ^c   Baralle, Diana ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Intron; NF1; Pseudoexon; PTB nPTB; Splicing

Indexed keywords

BINDING PROTEIN; CIS ACTING ELEMENT; NEUROFIBROMIN; NEURONAL POLYPYRIMIDINE TRACT BINDING PROTEIN; POLYPYRIMIDINE TRACT BINDING PROTEIN; TRANS ACTING FACTOR; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EXON; EXONIZATION; GENE DELETION; GENE MAPPING; GENE MUTATION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NEUROFIBROMATOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PSEUDOEXON; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

ALTERNATIVE SPLICING; BASE SEQUENCE; ENHANCER ELEMENTS, GENETIC; EXONS; GENE EXPRESSION REGULATION; GENES, NEUROFIBROMATOSIS 1; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEUROFIBROMIN 1; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYPYRIMIDINE TRACT-BINDING PROTEIN; RNA PRECURSORS; RNA SPLICING; RNA-BINDING PROTEINS; SEQUENCE DELETION;

EID: 56849094416     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06734.x     Document Type: Article

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