Death signal transduction induced by co-immobilized TNF-α plus IFN-γ and the development of polymeric anti-cancer drugs

Biomaterials

Volumn 31, Issue 34, 2010, Pages 9074-9085

  Guan, Yan Qing ^a   Li, Zhibin ^a   Liu, Jun Ming ^a,b,c  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c INTERNATIONAL CENTRE FOR MATERIALS PHYSICS   (China)

Author keywords

Co immobilized TNF plus IFN ; HeLa; IFNR2; STAT1; TNFR1; Tyrosine 701 phosphorylation

Indexed keywords

HELA; IFNR2; STAT1; TNFR1; TYROSINE 701 PHOSPHORYLATION;

AMINO ACIDS; BACTERIOPHAGES; CELL DEATH; CELL MEMBRANES; PHOSPHATASES; PHOSPHORYLATION; SIGNALING;

SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENT; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GAMMA INTERFERON; SERINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TYROSINE;

APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL DEATH; CELL NUCLEUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DISCOVERY; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; IMMOBILIZED PROTEINS; INTERFERON-GAMMA; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; POLYMERS; PROTEIN BIOSYNTHESIS; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; SPECTRUM ANALYSIS; STAT1 TRANSCRIPTION FACTOR; SURFACE PROPERTIES; TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77957303448     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.044     Document Type: Article

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