The reciprocal regulation of γ-synuclein and IGF-I receptor expression creates a circuit that modulates IGF-I signaling

Journal of Biological Chemistry

Volumn 285, Issue 40, 2010, Pages 30480-30488

  Li, Minjing ^a   Yin, Yancun ^a   Hua, Hui ^a   Sun, Xiangming ^a   Luo, Ting ^a   Wang, Jiao ^b   Jiang, Yangfu ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; INSULIN RECEPTORS; INSULIN-LIKE GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; OVER-EXPRESSION; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEASOMAL DEGRADATION; RECEPTOR EXPRESSION; RECIPROCAL REGULATION; SIGNALING COMPONENTS; STEADY-STATE LEVEL; SYNUCLEIN; TUMOR PROGRESSIONS;

CELL PROLIFERATION; INSULIN; PHOSPHORYLATION; TUMORS;

SIGNALING;

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; GAMMA SYNUCLEIN; INSULIN RECEPTOR SUBSTRATE; INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; IRS2 PROTEIN, HUMAN; MAPK1 PROTEIN, HUMAN; PROTEASOME;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; CELL MOTION; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; METABOLISM; NEOPLASM; PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL MOVEMENT; CELL PROLIFERATION; GAMMA-SYNUCLEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASMS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77957270195     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.131698     Document Type: Article

References (52)

1. Sjögren, K., Liu, J. L., Blad, K., Skrtic, S., Vidal, O., Wallenius, V., LeRoith, D., Törnell, J., Isaksson, O. G., Jansson, J. O., and Ohlsson, C. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 7088-7092
2. Isaksson, O. G., Lindahl, A., Nilsson, A., and Isgaard, J. (1987) Endocr. Rev. 8, 426-438
3. Daughaday, W. H., and Rotwein, P. (1989) Endocr. Rev. 10, 68-91
4. Lund, P. K., Moats-Staats, B. M., Hynes, M. A., Simmons, J. G., Jansen, M., D'Ercole, A. J., and Van Wyk, J. J. (1986) J. Biol. Chem. 261, 14539-14544
5. Bach, L. A., and Rechler, M. M. (1995) Diabetes Rev. 3, 38-61
6. Firth, S. M., and Baxter, R. C. (2002) Endocr. Rev. 23, 824-854
7. Ullrich, A., Gray, A., Tam, A. W., Yang-Feng, T., Tsubokawa, M., Collins, C., Henzel, W., Le Bon, T., Kathuria, S., Chen, E., Jacobs, S., Francke, U., Ramachandran, J., and Fujita-Yamaguchi, Y. (1986) EMBO J. 5, 2503-2512
8. Grey, A., Chen, Q., Xu, X., Callon, K., and Cornish, J. (2003) Endocrinology 144, 4886-4893
9. Ohlsson, C., Mohan, S., Sjögren, K., Tivesten, A., Isgaard, J., Isaksson, O., Jansson, J. O., and Svensson, J. (2009) Endocr. Rev. 30, 494-535
10. Chan, J. M., Stampfer, M. J., Giovannucci, E., Gann, P. H., Ma, J., Wilkinson, P., Hennekens, C. H., and Pollak, M. (1998) Science 279, 563-566
11. Hankinson, S. E., Willett, W. C., Colditz, G. A., Hunter, D. J., Michaud, D. S., Deroo, B., Rosner, B., Speizer, F. E., and Pollak, M. (1998) Lancet 351, 1393-1396
12. Ma, J., Pollak, M. N., Giovannucci, E., Chan, J. M., Tao, Y., Hennekens, C. H., and Stampfer, M. J. (1999) J. Natl. Cancer Inst. 91, 620-625
13. Yu, H., Spitz, M. R., Mistry, J., Gu, J., Hong, W. K., and Wu, X. F. (1999) J. Natl. Cancer Inst. 91, 151-156
14. Peyrat, J. P., Bonneterre, J., Hecquet, B., Vennin, P., Louchez, M. M., Fournier, C., Lefebvre, J., and Demaille, A. (1993) Eur. J. Cancer 29A, 492-497
15. Wu, Y., Yakar, S., Zhao, L., Hennighausen, L., and LeRoith, D. (2002) Cancer Res. 62, 1030-1035
16. Sonntag, W. E., Carter, C. S., Ikeno, Y., Ekenstedt, K., Carlson, C. S., Loeser, R. F., Chakrabarty, S., Lee, S., Bennett, C., Ingram, R., Moore, T., and Ramsey, M. (2005) Endocrinology 146, 2920-2932
17. Hakam, A., Yeatman, T. J., Lu, L., Mora, L., Marcet, G., Nicosia, S. V., Karl, R. C., and Coppola, D. (1999) Hum. Pathol. 30, 1128-1133
18. Hellawell, G. O., Turner, G. D., Davies, D. R., Poulsom, R., Brewster, S. F., and Macaulay, V. M. (2002) Cancer Res. 62, 2942-2950
19. Resnik, J. L., Reichart, D. B., Huey, K., Webster, N. J., and Seely, B. L. (1998) Cancer Res. 58, 1159-1164
20. Reinmuth, N., Fan, F., Liu, W., Parikh, A. A., Stoeltzing, O., Jung, Y. D., Bucana, C. D., Radinsky, R., Gallick, G. E., and Ellis, L. M. (2002) Lab. Invest. 82, 1377-1389
21. Dunn, S. E., Ehrlich, M., Sharp, N. J., Reiss, K., Solomon, G., Hawkins, R., Baserga, R., and Barrett, J. C. (1998) Cancer Res. 58, 3353-3361
22. Prager, D., Li, H. L., Asa, S., and Melmed, S. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 2181-2185
23. Surguchov, A. (2008) Int. Rev. Cell Mol. Biol. 270, 225-317
24. Clayton, D. F., and George, J. M. (1998) Trends Neurosci. 21, 249-254
25. Uversky, V. N., Li, J., Souillac, P., Millett, I. S., Doniach, S., Jakes, R., Goedert, M., and Fink, A. L. (2002) J. Biol. Chem. 277, 11970-11978
26. Zhao, W., Liu, H., Liu, W., Wu, Y., Chen, W., Jiang, B., Zhou, Y., Xue, R., Luo, C., Wang, L., Jiang, J. D., and Liu, J. W. (2006) Int. J. Oncol. 28, 1081-1088
27. Yanagawa, N., Tamura, G., Honda, T., Endoh, M., Nishizuka, S., and Motoyama, T. (2004) Clin. Cancer Res. 10, 2447-2451
28. Ji, H., Liu, Y. E., Jia, T., Wang, M., Liu, J., Xiao, G., Joseph, B. K., Rosen, C., and Shi, Y. E. (1997) Cancer Res. 57, 759-764
29. Hibi, T., Mori, T., Fukuma, M., Yamazaki, K., Hashiguchi, A., Yamada, T., Tanabe, M., Aiura, K., Kawakami, T., Ogiwara, A., Kosuge, T., Kitajima, M., Kitagawa, Y., and Sakamoto, M. (2009) Clin. Cancer Res. 15, 2864-2871
30. Bruening, W., Giasson, B. I., Klein-Szanto, A. J., Lee, V. M., Trojanowski, J. Q., and Godwin, A. K. (2000) Cancer 88, 2154-2163
31. Guo, J., Shou, C., Meng, L., Jiang, B., Dong, B., Yao, L., Xie, Y., Zhang, J., Chen, Y., Budman, D. R., and Shi, Y. E. (2007) Int. J. Cancer 121, 1296-1305
32. Hu, H., Sun, L., Guo, C., Liu, Q., Zhou, Z., Peng, L., Pan, J., Yu, L., Lou, J., Yang, Z., Zhao, P., and Ran, Y. (2009) Clin. Cancer Res. 15, 5485-5493
33. Jia, T., Liu, Y. E., Liu, J., and Shi, Y. E. (1999) Cancer Res. 59, 742-747
34. Gupta, A., Inaba, S., Wong, O. K., Fang, G., and Liu, J. W. (2003) Oncogene 22, 7593-7599
35. Hua, H., Xu, L., Wang, J., Jing, J., Luo, T., and Jiang, Y. (2009) J. Pathol. 217, 507-515
36. Jiang, Y., Liu, Y. E., Lu, A., Gupta, A., Goldberg, I. D., Liu, J., and Shi, Y. E. (2003) Cancer Res. 63, 3899-3903
37. Jiang, Y., Liu, Y. E., Goldberg, I. D., and Shi, Y. E. (2004) Cancer Res. 64, 4539-4546
38. Pan, Z. Z., Bruening, W., Giasson, B. I., Lee, V. M., and Godwin, A. K. (2002) J. Biol. Chem. 277, 35050-35060
39. Gupta, A., Godwin, A. K., Vanderveer, L., Lu, A., and Liu, J. W. (2003) Cancer Res. 63, 664-673
40. Chiou, S. T., and Chang, W. C. (1992) Biochem. Biophys. Res. Commun. 183, 524-531
41. Monnier, D., Boutillier, A. L., Giraud, P., Chiu, R., Aunis, D., Feltz, P., Zwiller, J., and Loeffler, J. P. (1994) Mol. Cell. Endocrinol. 104, 139-145
42. Dupont, J., Khan, J., Qu, B. H., Metzler, P., Helman, L., and LeRoith, D. (2001) Endocrinology 142, 4969-4975
43. Valverde, A. M., Lorenzo, M., Pons, S., White, M. F., and Benito, M. (1998) Mol. Endocrinol. 12, 688-697
44. Yarden, Y., and Sliwkowski, M. X. (2001) Nat. Rev. Mol. Cell Biol. 2, 127-137
45. Lu, Z., and Hunter, T. (2009) Ann. Rev. Biochem. 78, 435-475
46. Shen, J., Riggs, P. K., Hensley, S. C., Schroeder, L. J., Traner, A. R., Kochan, K. J., Person, M. D., and DiGiovanni, J. (2007) Mol. Carcinog. 46, 331-340
47. Lee, A. S. (2007) Cancer Res. 67, 3496-3499
48. Roudabush, F. L., Pierce, K. L., Maudsley, S., Khan, K. D., and Luttrell, L. M. (2000) J. Biol. Chem. 275, 22583-22589
49. Zhang, X., and Yee, D. (2000) Breast Cancer Res. 2, 170-175
50. Liu, H., Liu, W., Wu, Y., Zhou, Y., Xue, R., Luo, C., Wang, L., Zhao, W., Jiang, J. D., and Liu, J. W. (2005) Cancer Res. 65, 7635-7643
51. Pan, Z. Z., Bruening, W., and Godwin, A. K. (2006) Int. J. Oncol. 29, 1201-1205
52. Sachdev, D., and Yee, D. (2007) Mol. Cancer Ther. 6, 1-12