The electrogenic Na+/HCO3- cotransport modulates resting membrane potential and action potential duration in cat ventricular myocytes

Journal of Physiology

Volumn 578, Issue 3, 2007, Pages 819-829

  Villa Abrille, María C ^a   Petroff, Martín G Vila ^a   Aiello, Ernesto A ^a  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BICARBONATE SODIUM COTRANSPORTER; CALCIUM; SODIUM; 4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; 4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAT; CELL ISOLATION; CELL MEMBRANE POTENTIAL; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART VENTRICLE; HYPERPOLARIZATION; MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; PH; PH MEASUREMENT; PRIORITY JOURNAL; REPOLARIZATION; SODIUM TRANSPORT; STOICHIOMETRY; ACTION POTENTIAL DURATION; CELL PH; CONTROLLED STUDY; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART REPOLARIZATION; PATCH CLAMP TECHNIQUE; STEADY STATE; VOLTAGE CLAMP TECHNIQUE; ACTION POTENTIAL; ANIMAL; DRUG EFFECT; PHYSIOLOGY;

4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID; ACTION POTENTIALS; ANIMALS; CATS; HEART VENTRICLES; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; SODIUM-BICARBONATE SYMPORTERS;

EID: 33846618854     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.120170     Document Type: Article

References (36)

1. - symport in rat cardiac myocytes. J Physiol 512 1, 137-148.
2. - cotransporter. J Biol Chem 273, 16810-16815.
3. + exchanger. Annu Rev Physiol 47, 545-560.
4. - cotransport in neuroglia. Glia 1, 355-357.
5. Bers DM (2001). Cardiac inotropy and Ca mismanagement. In Excitation-Contraction Coupling and Cardiac Contractile Force, 2nd edn, ed. Bers DM, pp. 273-331. Kluwer Academic Publishers, Dordrecht.
6. Boron WF & Boulpaep EL (1983). Intracellular pH regulation in the renal proximal tubule of the salamander. J General Physiol 8, 53-94.
7. - cotransport. Am J Physiol Cell Physiol 267, C1633-C1640.
8. i after an increase in heart rate. Circ Res 79, 698-704.
9. Camilión de Hurtado MC, Pérez NG & Cingolani HE (1995). An electrogenic sodium-bicarbonate cotransport in the regulation of myocardial intracellular pH. J Mol Cell Cardiol 27, 231-242.
10. 3-co-transport, intracellular buffering and intracellular pH in guinea-pig ventricular myocytes. J Physiol 552, 715-726.
11. Choi I, Aalkjaer C, Boulpaep EL & Boron WF (2000). An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel. Nature 405, 571-575.
12. - cotransporter isoform (hhNBC). Am J Physiol Cell Physiol 276, C576-C584.
13. Coraboeuf E, Deroubaix E & Hoerter J (1976). Control of ionic permeabilities in normal and ischemic heart. Circ Res 38, I92-I98.
14. - symport in the sheep cardiac Purkinje fibre. J Physiol 451, 365-385.
15. Deitmer JW & Schlue WR (1989). An inwardly directed electrogenic sodium-bicarbonate co-transport in leech glial cells. J Physiol 411, 179-194.
16. 3 absorption across the retinal pigment epithelium. J Gen Physiol 94, 125-150.
17. + flux measurements. J Biol Chem 260, 15554-15560.
18. Khandoudi N, Albadine J, Robert P, Krief S, Berrebi-Bertrand I, Martin X, Bevensee MO, Boron WF & Bril A (2001). Inhibition of the cardiac electrogenic sodium bicarbonate cotransporter reduces ischemic injury. Cardiovasc Res 52, 387-396.
19. Korn SJ, Marty A, Connor JA & Horn R (1991). Perforated patch recording. Meth Neurosciences 4, 364-373.
20. Lagadic-Gossman DK, Buckler J & Vaughan-Jones RD (1992). Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte. J Physiol 458, 361-384.
21. + concentration at different moments during the action potential in guinea-pig myocytes. J Physiol 478, 493-504.
22. Newman EA (1991). Sodium-bicarbonate cotransport in retinal glia of the salamander. J Neuroscience 11, 3972-3983.
23. + antiport in Chinese hamster lung fibroblasts. J Biol Chem 258, 3503-3508.
24. Poole-Wilson PA & Langer GA (1975). Effect of pH on ionic exchange and function in rat and rabbit myocardium. Am J Physiol 229, 570-581.
25. Pushkin A, Abuladze N, Lee I, Newman D, Hwang J & Kurtz I (1999). Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family. J Biol Chem 274, 16569-16575.
26. Pushkin A, Abuladze N, Newman D, Lee I, Xu G & Kurtz I (2000). Cloning, characterization and chromosomal assignment of NBC4, a new member of the sodium bicarbonate cotransporter family. Biochim Biophys Acta 1493, 215-218.
27. - symporter in the rat heart after myocardial infarction. J Am Coll Cardiol 37, 2154-2165.
28. Sassani P, Pushkin A, Gross E, Gomer A, Abuladze N, Dukkipati R, Carpenito G & Kurtz I (2002). Functional characterization of NBC4: A new electrogenic sodium-bicarbonate cotransporter. Am J Physiol Cell Physiol 282, C408-C416.
29. Schafer C, Ladilov YV, Siegmund B & Piper HM (2000). Importance of bicarbonate transport for protection of cardiomyocytes against reoxygenation injury. Am J Physiol Heart Circ Physiol 278, H1457-H1463.
30. 3 -cotransporter, rkNBC, expressed in oocytes. Am J Physiol Renal Physiol 277, F611-F623.
31. Spitzer KW & Hogan PM (1979). The effects of acidosis and bicarbonate on action potential repolarization in canine cardiac Purkinje fibers. J Gen Physiol 73, 199-218.
32. i recovery after global ischemia in the perfused heart. Circ Res 72, 993-1003.
33. + transport mechanisms in cardiac hypertrophy and failure. J Mol Cell Cardiol 35, 5-25.
34. Vila Petroff MG, Aiello EA, Palomeque J, Salas MA & Mattiazzi AR (2000). Subcellular mechanisms of the positive inotropic effect of angiotensin II in cat myocardium. J Physiol 529, 189-203.
35. - cotransporter (NBCe2). Am J Physiol Cell Physiol 282, C1278-C1289.
36. - cotransport in ventricular myocytes from rat, rabbit and guinea pig. J Physiol 562, 455-475.