Angiotensin II and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA

Circulation Research

Volumn 98, Issue 8, 2006, Pages 1040-1047

  Zhou, Chaoming ^a   Ziegler, Chandra ^a   Birder, Lori A ^a   Stewart, Alexandre F R ^b   Levitan, Edwin S ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Angiotensin; mRNA stability; NADPH oxidase; Potassium channel; ROS; Stretch

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; APOPTOSIS SIGNAL REGULATING KINASE 1; CATALASE; ENZYME INHIBITOR; HYDROGEN PEROXIDE; MESSENGER RNA; POTASSIUM CHANNEL KV4.3; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CLINICAL PATHWAY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; HEART CELL CULTURE; HEART HYPERTROPHY; HEART VENTRICLE WALL; MOUSE; MUSCLE CELL; NEWBORN; NONHUMAN; PATHOGENESIS; POTASSIUM CURRENT; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

3' UNTRANSLATED REGIONS; ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CLONING, MOLECULAR; ENZYME ACTIVATION; EXPRESSED SEQUENCE TAGS; GENES, REPORTER; HEART; HUMANS; MICE; MUSCLE CELLS; MYOCARDIUM; NADPH OXIDASE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SHAL POTASSIUM CHANNELS;

EID: 33646796766     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000218989.52072.e7     Document Type: Article

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