Dietary flaxseed supplementation improves endothelial function in the mesenteric arterial bed

Food Research International

Volumn 43, Issue 8, 2010, Pages 2052-2056

  Daleprane, Julio Beltrame ^a   Batista, Aline ^a   Pacheco, Juliana Tomaz ^a   da Silva, Andréa F E ^b   Costa, Cristiane A ^b   Resende, Ângela de Castro ^b   Boaventura, Gilson Teles ^a  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^b STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Diet; Endothelial function; Flaxseed; Lipid profile; Mesenteric arterial bed

Indexed keywords

DIET; ENDOTHELIAL FUNCTION; FLAXSEED; LIPID PROFILE; MESENTERIC ARTERIAL BED;

BLOOD; GLYCEROL; NUTRITION; RATS; SELF ASSEMBLY;

FLAX;

FLAX; GLYCEROL; LIPIDS; NUTRITION; RODENTS; SEEDS;

RATTUS;

EID: 77957164857     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodres.2010.06.004     Document Type: Article

References (46)

1. Aguiar A.C., Morais D.R., Santos L.P., Stevanato F.B., Visentainer J.E., de Souza N.E., et al. Effect of flaxseed oil in diet on fatty acid composition in the liver of Nile tilapia (Oreochromis niloticus). Archivos latinoamericanos de nutrición 2007, 57(3):273-277.
2. Albuquerque K., Sardinha F., Telles M., Watanabe R., Nascimento C., Tavaresdocarmo M., et al. Intake of trans fatty acid rich hydrogenated fat during pregnancy and lactation inhibits the hypophagic effect of central insulin in the adult offspring. Nutrition 2006, 22:820-829.
3. Bhathena S.J., Ali A.A., Haudenschild C., Latham P., Ranich T., Mohamed A.I., et al. Dietary flaxseed meal is more protective than soy protein concentrate against hypertriglyceridemia and steatosis of the liver in an animal model of obesity. Journal of the American College of Nutrition 2003, 22(2):157-164.
4. Bierenbaum M.L., Reichstein R., Watkins T.R. Reducing atherogenic risk in hyperlipemic humans with flax seed supplementation: A preliminary report. Journal of the American College of Nutrition 1993, 12:501-504.
5. Ceylan-Isik A., Hünkar T., Aşan E., Kaymaz F., Ari N., Söylemezoǧlu T., et al. Cod liver oil supplementation improves cardiovascular and metabolic abnormalities in streptozotocin diabetic rats. Journal of Pharmacy and Pharmacology 2007, 59(12):1629-1641.
6. Chalmers L., Kaskel F.J., Bamgbola O. The role of obesity and its bioclinical correlates in the progression of chronic kidney disease. Advances in Chronic Kidney Disease 2006, 13(4):352-364.
7. Cicero A.F., Ertek S., Borghi C. Omega-3 polyunsaturated fatty acids: their potential role in blood pressure prevention and management. Current Vascular Pharmacology 2009, 7(3):330-337.
8. Clark W.F., Parbtani A., Huff M.W., Spanner E., de Salis H., Chin-Yee I., et al. Flaxseed: A potential treatment for lupus nephritis. Kidney International 1995, 48(2):475-480.
9. Cunnane S.C., Hamadeh M.J., Liede A.C., Thompson L.U., Wolever T.M., Jenkins D.J. Nutritional attributes of traditional flaxseed in healthy young adults. American Journal of Clinical Nutrition 1995, 61(1):62-68.
10. Cunnane S.C., Ganguli S., Menard C., Liede A.C., Hamadeh M.J., Chen Z.Y., et al. High alpha-linolenic acid flaxseed (Linum usitatissimum): Some nutritional properties in humans. British Journal of Nutrition 1993, 69(2):443-453.
11. Daleprane J.B., Feijó T.S., Boaventura G.T. Organic and genetically modified soybean diets: Consequences in growth and in hematological indicators of aged rats. Plant Foods for Human Nutrition 2009, 64(1):1-5.
12. Daleprane J.B., Pacheco J.T., Boaventura G.T. Evaluation of protein quality from genetically modified and organic soybean in two consecutives generations of Wistar rats. Brazilian Archives of Biology and Technology 2009, 52(4):841-847.
13. Dupasquier C.M., Weber A.M., Ander B.P., Rampersad P.P., Steigerwald S., Wigle J.T., et al. Effects of the flaxseed lignans secoisolariciresinol diglucoside and its aglycone on serum and hepatic lipids in hyperlipidaemic rats. British Journal of Nutrition 2009, 102(3):361-369.
14. Figueiredo M.S., de Moura E.G., Lisboa P.C., Troina A.A., Trevenzoli I.H., Oliveira E., et al. Flaxseed supplementation of rats during lactation changes the adiposity and glucose homeostasis of their offspring. Life Science 2009, 85(9-10):365-371.
15. Flack J.M., Peters R., Shafi T., Alrefai H., Nasser S.A., Crook E. Prevention of hypertension and its complications: Theoretical basis and guidelines for treatment. Journal of the American Society of Nephrology 2003, 14(7):S92-S98.
16. Freedland S.J., Aronson W.J. Dietary intervention strategies to modulate prostate cancer risk and prognosis. Current Opinion in Urology 2009, 19(3):263-267.
17. Ghafoorunissa V.R., Sesikaran B. Palmolein and groundnut oil have comparable effects on blood lipids and platelet aggregation in healthy Indian subjects. Lipids 1995, 30:1163-1169.
18. Hansen C. From fish to flaxseed. Reducing cardiac risk with omega-3 fatty acids. Advance for Nurse Practitioners 2006, 14(5):51-53.
19. Hussein N., Ah-Sing E., Wilkinson P., Leach C., Griffin B.A., Millward D.J. Long-chain conversion of [13C] linoleic acid and alpha-linolenic acid in response to marked changes in their dietary intake in men. Journal Lipid Research 2005, 46(2):269-280.
20. Jenkins D.J.A., Kendall C.W.C., Vidgen E. Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity: Controlled crossover trial. American Journal of Clinical Nutrition 1999, 69:395-402.
21. Lawson D.L., Mehta J.L., Saldeen K., Mehta P., Saldeen T.G. Omega-3 polyunsaturated fatty acids augment endothelium-dependent vasorelaxation by enhanced release of EDRF and vasodilator prostaglandins. Eicosanoids 1991, 4(4):217-223.
22. Lepage G., Roy C.C. Direct transesterification of all classes of lipids in a one-step reaction. Journal Lipid Research 1986, 27:114-120.
23. Lillo J.L. The endocannabinoid system as a novel approach for managing obesity. Journal of American Osteopathic Association 2007, 107(4):S12-S20.
24. Makni M., Fetoui H., Gargour N.K., Garouiel M., Jaber H., Makni J., et al. Hypolipidemic and hepatoprotective effects of flax and pumpkin seed mixture rich in omega-3 and omega-6 fatty acids in hypercholesterolemic rats. Food and Chemical Toxicology 2008, 46(12):3714-3720.
25. Mandasescu S., Mocanu V., Dascalita A.M., Haliga R., Nestian I., Stitt P.A., et al. Flaxseed supplementation in hyperlipidemic patients. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 2005, 109:502-506.
26. McGregor D.D. The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessel of the rat. Journal of Physiology 1965, 177:21-30.
27. Mindrescu C., Gupta R.P., Hermance E.V., DeVoe M.C., Soma V.R., Coppola J.T., et al. Omega-3 fatty acids plus rosuvastatin improves endothelial function in South Asians with dyslipidemia. Vascular Health and Risk Management 2008, 4(6):1439-1447.
28. Mitchell R.W., Kroeger E.A., Gilchrist J.S., Moghadasian M.M., Lukas A., Pierce G.N. Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits. American Journal of Physiology Heart Circulation Physiology 2006, 291(6):H2987-H2996.
29. Nies L.K., Cymbala A.A., Kasten S.L., Lamprecht D.G., Olson K.L. Complementary and alternative therapies for the management of dyslipidemia. Annals of Pharmacotherapy 2006, 40(11):1984-1992.
30. Paschos G.K., Magkos F., Panagiotakos D.B., Votteas V., Zampelas A. Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients. European Journal of Clinical Nutrition 2007, 61(10):1201-1206.
31. Paschos G.K., Zampelas A., Panagiotakos D.B., Katsiougiannis S., Griffin B.A., Votteas V., et al. Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men. European Journal of Clinical Nutrition 2007, 46(6):315-320.
32. Prasad K. Dietary flaxseed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis 1997, 132:69-76.
33. Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 1999, 99:1355-1362.
34. Prasad K. Flaxseed: A source of hypercholetsterolemic and antiatherogenic agent. Drug News Perspect 2000, 13:99-104.
35. Prasad K. Antihypertensive activity of secoisolariciresinol diglucoside (SDG) isolated from flaxseed: Role of guanylate cyclase. International Journal of Angiology 2004, 13:7-14.
36. Prasad K. A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complex. Journal of Cardiovascular Pharmacology Therapy 2007, 12(4):304-313.
37. Prasad K. Flaxseed and cardiovascular health. Journal of Cardiovascular Pharmacology 2009, 54(5):369-377.
38. Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. Journal of Nutrition 1993, 123(11):1939-1951.
39. Resende A.C., Ballejo G., Salgado M.C. Role of non-nitric oxide non-prostaglandin endothelium-derived relaxing factor(s) in bradykinin vasodilation. Brazilian Journal of Medical and Biological Research 1998, 31(9):1229-1235.
40. Sekine S., Sasanuki S., Murano Y., Aoyama T., Takeuchi H. Alpha-linolenic acid-rich flaxseed oil ingestion increases plasma adiponectin level in rats. International Journal for Vitamin and Nutrition Research 2008, 78(4-5):223-229.
41. Soares L.L., Lucas A.M.M., Boaventura G.T. Can organic and transgenic soy be used as a substitute for animal protein by rats?. Brazilian Journal of Medical and Biological Research 2005, 38:583-586.
42. Thies F., Miles E.A., Nebe-von-Caron G., Powell J.R., Hurst T.L., Newsholme E.A., et al. Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. Lipids 2001, 36(11):1183-1193.
43. Troina A.A., Figueiredo M.S., Moura E.G., Boaventura G.T., Soares L.L., Cardozo L.F., et al. Maternal flaxseed diet during lactation alters milk composition and programs the offspring body composition, lipid profile and sexual function. Food and Chemical Toxicology 2009, 48(2):697-703.
44. Walisundera M.N., Ratnayake W.A., Behrens P.W. Chemical and nutritional studies of flaxseed (variety Linott) in rats. Journal of Nutritional Biochemistry 1992, 3:232-240.
45. Yuan J.P., Li X., Xu S.P., Wang J.H., Liu X. Hydrolysis kinetics of secoisolariciresinol diglucoside oligomers from flaxseed. Journal of Agricultural and Food Chemistry 2008, 56(21):10041-10047.
46. Zhang W., Wang X., Liu Y., Tian H., Flickinger B., Empie M.W., et al. Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects. British Journal of Nutrition 2008, 99(6):1301-1309.