Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed

Circulation

Volumn 99, Issue 10, 1999, Pages 1355-1362

  Prasad, Kailash ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Antioxidants; Atherosclerosis; Chemiluminescence; Flaxseed; Hypercholesterolemia

Indexed keywords

ANTIOXIDANT; CHOLESTEROL; LIGNAN; LIPOPROTEIN; MALONALDEHYDE; PLANT EXTRACT; SECOISOLARICIRESINOL DIGLUCOSIDE; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DRUG STRUCTURE; FLAX; HYPERCHOLESTEROLEMIA; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0033574164     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.10.1355     Document Type: Article

References (32)

1. Prasad K, Kalra J. Oxygen free radicals and hypercholesterolemic atherosclerosis: effect of vitamin E. Am Heart J. 1993;125:958-973.
2. Prasad K, Kalra J, Lee P. Oxygen free radicals as a mechanism of hypercholesterolemic atherosclerosis: effects of probucol. Int J Angiol. 1994;3:100-112.
3. Steinberg D. Antioxidants in the prevention of human atherosclerosis. Circulation. 1992;85:2338-2345.
4. Pignol B, Henane S, Mencia-Huerta JM, Rola-Pleszczynski M, Braquet P. Effect of platelet-activating factor (PAF-acether) and its specific receptor antagonist, BN 52021, on interleukin 1 (IL1) release and synthesis by rat spleen adherent monocytes. Prostaglandins. 1987;33:931-939.
5. Bonavida B, Mencia-Huerta JM, Braquet P. Effect of platelet-activating factor on monocyte activation and production of tumor necrosis factor. Int Arch Allergy Appl Immunol. 1989;88:157-160.
6. 4. Biochim Biophys Acta. 1984;803:271-277.
7. Shaw JO, Pinckard RN, Ferrigni KS, McManus LM, Hanahan DJ. Activation of human neutrophils with 1-O-hexadecyl/octadecyl-2-actyl-sn-glycerol-3-phosphorylcholine (platelet-activating factor). J Immunol. 1981;127:1250-1255.
8. Braquet P, Hosford D, Braquet M, Bourgain R, Bussolino F. Role of cytokines and platelet-activating factor in microvascular immune injury. Int Arch Allerg Appl Immunol. 1989;88:88-100.
9. Paubert-Braquet M, Lonchampt MO, Koltz P, Guilbaud J. Tumor necrosis factor (TNF) primes human neutrophil (PMN) platelet-activating factor (PAF)-induced superoxide generation: consequences in promoting PMN-mediated endothelial cell (EC) damages. Prostaglandins. 1988; 35:803. Abstract.
10. Carter J. Flax seed as a source of alpha linolenic acid. J Am Coll Nutr. 1993;12:551.
11. Cunnane SC, Ganguli S, Menard C, Liede AC, Hamadeh MJ, Chen Z-Y, Wolever TMS, Jenkins DJA. High alpha-linolenic acid flaxseed (Linum usit atissimum): some nutritional properties in humans. Br J Nutr. 1993; 69:443-453.
12. Hunter JE. n-3 fatty acids from vegetable oils. Am J Clin Nutr. 1990;51: 809-814.
13. Bakke JE, Klosterman HJ. A new diglucoside from flaxseed. Proc North Dakota Acad Sci. 1956;10:18-22.
14. Prasad K. Dietary flaxseed in the prevention of hypercholesterolemic atherosclerosis. Atherosclerosis. 1997;132:69-76.
15. Prasad K, Mantha SV, Muir AD, Westcott ND. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Atherosclerosis. 1998;136:367-375.
16. Westcott ND, Muir AD. Process for Extracting Lignans From Flaxseed. US patent 5 705 618, January 6, 1998.
17. Cox CP, Wood KL. Selective antagonism of platelet-activating factor (PAF)-induced aggregation and secretion of washed rabbit platelets by CV-3988, L-652731, triazolam and alprazolam. Thromb Res. 1987;47: 249-257.
18. Prasad K. Hydroxyl radical scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flaxseed. Mol Cell Biochem. 1997;168: 117-123.
19. Wilson PW, Abbot RD, Garrison RJ, Castelli WP. Estimation of very low-density lipoprotein cholesterol from data on triglyceride concentrations in plasma. Clin Chem. 1981;27:2008-2010.
20. Friedwald WT, Levy RRI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without the use of preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
21. Kapoor R, Prasad K. Role of oxyradicals in cardiovascular depression and cellular injury in hemorrhagic shock and reinfusion: effect of SOD and catalase. Circ Shock. 1994;43:79-94.
22. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal Biochem. 1979;95:351-358.
23. Holman RS, McGill HC Jr, Strong JP, Greer JC. Technics for studying atherosclerotic lesions. Lab Invest. 1958;7:42-47.
24. Drury RAB, Wallington EA. Carleson's Histological Technique. 5th ed. New York, NY: Oxford University Press; 1980:195, 291.
25. Prasad K, Mantha SV, Kalra J, Kapoor R, Kamalarajan BRC. Purpurogallin in the retardation of hypercholesterolemic atherosclerosis. Int J Angiol. 1997;6:157-166.
26. Pearson TA, Malros H, Dillman J, Sternby N, Heptinstall RH. Atherosclerosis in hypercholesterolemic hare: comparison of coronary artery lesions induced by dietary cholesterol in the hare and rabbit. Atherosclerosis. 1987;63:125-135.
27. Rouleau JL, Parmley WW, Stevens J, Wikman-Coffelt J, Sievers R, Mahley RW, Havel RJ, Brecht W. Verapamil suppresses atherosclerosis in cholesterol fed rabbits. J Am Coll Cardiol. 1983;1:1453-1460.
28. Warren JS, Ward PA. Oxidative injury to vascular endothelium. Am J Med Sci. 1983;292:97-103.
29. Egan RW, Paxton J, Kuehl FA Jr. Mechanism for irreversible self-deactivation of prostaglandin synthesis. J Biol Chem. 1976;251:7329-7335.
30. Murota SI, Morita I, Suda N. The control of vascular endothelial cell injury. Ann N Y Acad Sci. 1990;598:182-187.
31. Sacks T, Moldow CF, Graddock PR, Bowers TK, Jacob HS. Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes: an in vitro model of immune vascular damage. J Clin Invest. 1978;61:1161-1167.
32. Ross R. The pathogenesis of atherosclerosis: an update. N Engl J Med. 1986;314:488-500.