Effects of enzymatic hydrolysis on lentil allergenicity

Molecular Nutrition and Food Research

Volumn 54, Issue 9, 2010, Pages 1266-1272

  Cabanillas, Beatriz ^a   Pedrosa, Mercedes M ^b   Rodríguez, Julia ^a   González, Ángela ^a   Muzquiz, Mercedes ^b   Cuadrado, Carmen ^a   Crespo, Jesús F ^a   Burbano, Carmen ^b  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b INIA   (Spain)

Author keywords

Allergens; Enzymatic hydrolysis; Food allergy; Legumes; Lentil

Indexed keywords

ALLERGEN; FLAVOURZYME; IMMUNOGLOBULIN E; PLANT EXTRACT; PROTEIN HYDROLYSATE; PROTEINASE; SUBTILISIN; VEGETABLE PROTEIN;

ARTICLE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOD ALLERGY; FOOD HANDLING; HUMAN; HYDROLYSIS; IMMUNOLOGY; LENTIL; METABOLISM; METHODOLOGY; PLANT SEED; TIME;

ALLERGENS; ENDOPEPTIDASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FOOD HANDLING; FOOD HYPERSENSITIVITY; HUMANS; HYDROLYSIS; IMMUNOGLOBULIN E; LENS PLANT; PLANT EXTRACTS; PLANT PROTEINS; PROTEIN HYDROLYSATES; SEEDS; SUBTILISINS; TIME FACTORS;

CICER ARIETINUM; FABACEAE; GLYCINE MAX; LENS CULINARIS;

EID: 77957061062     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900249     Document Type: Article

References (30)

1. Leterme, P., Recommendations by health organizations for pulse consumption. Br. J. Nutr. 2002, 3, S239-S242.
2. Scarafoni, A., Magni, C., Duranti, M., Molecular nutraceutics as a mean to investigate the positive effects of legume seed proteins on human health. Trends Food Sci. Technol. 2007, 18, 454-463.
3. Thavarajah, D., Thavarajah, P., Sarker, A., Vandenberg, A., Lentils (Lens culinaris Medikus subspecies culinaris): a whole food for increased iron and zinc intake. J. Agric. Food Chem. 2009, 57, 5413-5419.
4. Pascual, C. Y., Fernandez-Crespo, J., Sanchez-Pastor, S., Padial, M. A. et al., Allergy to lentils in Mediterranean pediatric patients. J. Allergy Clin. Immunol. 1999, 103, 154-158.
5. Martinez San Ireneo, M., Ibanez Sandin, M. D., Fernandez-Caldas, E., Hypersensitivity to members of the botanical order Fabales (legumes). J. Investig. Allergol. Clin. Immunol. 2000, 10, 187-199.
6. Patil, S. P., Niphadkar, P. V., Bapat, M. M., Chickpea: a major food allergen in the Indian subcontinent and its clinical and immunochemical correlation. Ann. Allergy Asthma Immunol. 2001, 87, 140-145.
7. Crespo, J. F., Pascual, C., Burks, A. W., Helm, R. M., Esteban, M. M., Frequency of food allergy in a pediatric population from Spain. Pediatr. Allergy Immunol. 1995, 6, 39-43.
8. Sanchez-Monge, R., Pascual, C. Y., Diaz-Perales, A., Fernandez-Crespo, J. et al., Isolation and characterization of relevant allergens from boiled lentils. J. Allergy Clin. Immunol. 2000, 106, 955-961
9. Lopez-Torrejon, G., Salcedo, G., Martin-Esteban, M., Diaz-Perales, A. et al., Len c 1 a major allergen and vicilin from lentil seeds: protein isolation and cDNA cloning. J. Allergy Clin. Immunol. 2003, 112, 1208-1215.
10. Merritt, R. J., Carter, M., Haight, M., Eisenberg, L. D., Whey protein hydrolysate formula for infants with gastrointestinal intolerance to cow milk and soy protein in infant formulas. J. Pediatr. Gastroenterol. Nutr. 1990, 11, 78-82.
11. Terracciano, L., Isoardi, P., Arrigoni, S., Zoja, A., Martelli, A., Use of hydrolysates in the treatment of cow0s milk allergy. Ann. Allergy Asthma Immunol. 2002, 89, 86-90.
12. Lee, H. W., Keum, E. H., Lee, S. J., Sung, D. E. et al., Allergenicity of proteolytic hydrolysates of the soybean 11S globulin. J. Food Sci. 2007, 72, C168-C172.
13. Burks, A. W., Williams, L. W., Thresher, W., Connaughton, C. et al., Allergenicity of peanut and soybean extracts altered by chemical or thermal denaturation in patients with atopic dermatitis and positive food challenges. J. Allergy Clin. Immunol. 1992, 90, 889-897.
14. Clemente, A., Vioque, J., Sanchez-Vioque, R., Pedroche, J., Millan, F., Production of extensive chickpea Cicer arietinum L., protein hydrolysates with reduced antigenic activity. J. Agric. Food Chem. 1999, 47, 3776-3781.
15. Clemente, A., Vioque, J., Sánchez-Vioque, R., Pedroche, J. et al., Protein quality of chickpea Cicer arietinum L., protein hydrolysates. Food Chem. 1999, 67, 269-274.
16. Sormus de Castro Pinto, S. E., Neves, V. A., Machado de Medeiros, B. M., Enzymatic hydrolysis of sweet lupin, chickpea, and lentil 11S globulins decreases their antigenic activity. J. Agric. Food Chem. 2009, 57, 1070-1075.
17. Lucas, J. S., Atkinson, R. G., What is a food allergen? Clin. Exp. Allergy 2008, 38, 1095-1099.
18. Clemente, A., Enzymatic protein hydrolysates in human nutrition. Trends Food Sci. Technol. 2000, 11, 254-262.
19. Cuadrado, C., Cabanillas, B., Pedrosa, M. M., Varela, A., Influence of termal processing on IgE reactivity to lentil and chickpea proteins. Mol. Nutr. Food Res. 2009, 53, 1462-1468.
20. Adler-Nissen, J., Determination of the degree of hydrolysis of food protein hydrolysates by trinitrobenzenesulfonic acid. J. Agric. Food Chem. 1979, 27, 1256-1262.
21. Laemmli, U. K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680-685.
22. Sanchez-Madrid, F., Morago, G., Corbi, A. L., Carreira, J., Monoclonal antibodies to three distinct epitopes on human IgE: their use for determination of allergen-specific IgE. J. Immunol. Methods 1984, 73, 367-378.
23. Siemensma, A. D., Weijer, W. J., Bark, H. J., The importance of peptide lengths in hypoallergenic infant formulae. Trends Food Sci. Technol. 1993, 4, 16-21.
24. Ziegler, F., Ollivier, J. M., Cynober, L., Masinin, J. P. et al., Efficiency of enteral nitrogen support in surgical patients: small peptides vs. non-degraded proteins. Gut 1990, 31, 1277-1288.
25. Walker-Smith, J., Hypoallergenic formulas: are they really hypoallergenic? Ann. Allergy Asthma Immunol. 2003, 90, 112-114.
26. Docena, G., Rozenfeld, P., Fernandez, R., Fossati, C. A., Evaluation of the residual antigenicity and allergenicity of cow's milk substitutes by in vitro tests. Allergy 2002, 57, 83-91.
27. Humiski, L. M., Aluko, R. E., Physicochemical and bitterness properties of enzymatic pea protein hydrolysates. J. Food Sci. 2007, 72, S605-S611.
28. Szymkiewicz, A., Jedrychowski, L., Reduction of inmunoreactive properties of pea globulins as the result of enzymatic modification. Acta. Alimentaria 2005, 34, 295-306.
29. Seo, W. H., Lee, H. G., Baek, H. H., Evaluation of bitterness in enzymatic hydrolysates of soy protein isolate by taste dilution analysis. J. Food Sci. 2008, 73, S41-S46.
30. Wickham, M., Faulks, R., Mills, C., In vitro digestion methods for assessing the effect of food structure on allergen breakdown. Mol. Nutr. Food Res. 2009, 53, 952-958.