Len c 1, a major allergen and vicilin from lentil seeds: Protein isolation and cDNA cloning

Journal of Allergy and Clinical Immunology

Volumn 112, Issue 6, 2003, Pages 1208-1215

  López Torrejón, Gema ^a   Salcedo, Gabriel ^a   Martín Esteban, Manuel ^b   Díaz Perales, Araceli ^a   Pascual, Cristina Y ^b   Sánchez Monge, Rosa ^a,c  

^a UNIVERSIDAD POLITÉCNICA DE MADRID   (Spain)

^b HOSPITAL INFANTIL LA PAZ   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Ara h 1; cDNA cloning; Food allergy; Lentil; Major allergen; Vicilin; Vicilin subunits

Indexed keywords

ALLERGEN; BINDING PROTEIN; FOOD ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E BINDING PROTEIN; LEN C 1.02 ALLERGEN; UNCLASSIFIED DRUG; VICILIN;

ADOLESCENT; ADULT; ALLERGIC REACTION; ALLERGY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; C TERMINAL DOMAIN; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLYCOSYLATION; HUMAN; ION EXCHANGE CHROMATOGRAPHY; LEGUME; LENTIL; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; NUT; PLANT SEED; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ISOLATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

EID: 0347626023     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2003.08.035     Document Type: Article

References (29)

1. Pascual CY, Fernandez-Crespo J, Sanchez-Pastor S, Padial MA. Diaz-Pena JM, Martin-Muñoz F, et al. Allergy to lentils in Mediterranean pediatrie patients. J Allergy Clin Immunol 1999;103:154-8.
2. Martinez M, Ibañez MD, Fernandez-Caldas E. Hypersensitivity to members of the botanical order Fabales (legumes). J Invest Allergol Clin Immunol 2000;10:187-99.
3. Patil SP, Niphadkar PV, Bapat MM. Chickpea: a major food allergen in the Indian subcontinent and its clinical and immunochemical correlation. Ann Allergy Asthma Immunol 2001;87:140-5.
4. Crespo JF, Pascual CY, Burks AW, Helm RM, Martin-Esteban M. Frequency of food allergy in a pediatric population from Spain. Pediatr Allergy Immunol 1995;6:39-43.
5. Ibañez D, Martinez M, Marañon F, Fernandez-Caldas E, Alonso E, Laso T. Specific IgE determinations to crude and boiled lentils (Lens culinaris) extracts in lentil-sensitive children and controls. Allergy 1999;54:1209-14.
6. Martin JA, Compaired JA, de la Hoz B, Quirce S, Alonso MD, Igea JM. et al. Bronchial asthma induced by chickpea and lentil. Allergy 1992;47:185-7.
7. Kalogeromitros D, Armenaka M, Galatas I, Capellau O, Katsarou A. Anaphylaxis induced by lentils. Ann Allergy Asthma Immunol 1996;77:480-2.
8. Niphadkar PV, Patil SP, Bapat MM. Chickpea-induced anaphylaxis. Allergy 1997;52:115-6.
9. Skolnick HS, Conover-Walker MK, Koerner CB, Sampson HA, Burks W, Wood RA. The natural history of peanut allergy. J Allergy Clin Immunol 2001;107:367-74.
10. Taylor SL, Lemanske RF Jr, Bush RK, Busse WW. Chemistry of food allergens. In: Chandra RK, editor. Food allergy. St Johns: Nutrition Research Education Foundation; 1987. p. 21-44.
11. Burks AW, William LW, Helm RM, Connaughton C, Cockrell G, O'Brien T. Identification of a major peanut allergen. Ara h 1, in patients with atopic dermatitis and positive peanut challenges. J Allergy Clin Immunol 1991;88:172-9.
12. Shin DS, Compadre CM, Maleki SJ, Kopper RA, Sampson H, Huang SK, et al. Biochemical and structural analysis of the IgE binding sites on Ara h 1, an abundant and highly allergenic peanut protein. J Biol Chem 1998;273:13753-9.
13. Ogawa T, Bando N, Tsuji H, Nishikawa K, Kitamura K. Alpha subunit of beta-conglycinin, an allergenic protein recognized by IgE antibodies of soybean-sensitive patients with atopic dermatitis. Biosci Biotech Biochem 1995;59:831-3.
14. Teuber SS, Jarvis KC, Dandekar AM, Peterson R, Ansari AA. Identification and cloning of a complementary DNA encoding a vicilin-like proprotein Jug r 2, from English walnut kernel (Junglas regia), a major food allergen. J Allergy Clin Immunol 1999;104:1311-20.
15. Wang F, Robotham JM, Teuber SS, Tawde P, Sathe SK, Roux KH. Ana o 1, a cashew (Anacardium occidental) allergen of the vicilin seed storage protein family. J Allergy Clin Immunol 2002;110:160-6.
16. Beyer K, Bardina L, Grishina G, Sampson HA. Identification of sesame seed allergens by 2-dimensional proteomics and Edman sequencing: seed storage proteins as common food allergens. J Allergy Clin Immunol 2002;110:154-9.
17. Shewry PR, Napier JA, Tatham AS. Seed storage proteins: structures and biosynthesis. Plant Cell 1995;7:945-56.
18. Casey R, Domoney C. Pea globulins. In: Shewry PR, Casey R, editors. Seed proteins. Dordrecht. The Netherlands: Kluwer Academic Publishers; 1999. p. 171-208.
19. Astwood JD, Silvanovich A, Bannon GA. Vicilins: a case study in allergen pedigrees. J Allergy Clin Immunol 2002;110:26-7.
20. Sanchez-Monge R, Pascual CY, Diaz-Perales A, Fernandez-Crespo J, Martin-Esteban M, Salcedo G. Isolation and characterization of relevant allergens from boiled lentils. J Allergy Clin Immunol 2000;106:955-61.
21. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of proteins utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
22. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985;150:76-85.
23. Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 1970;227:680-5.
24. Lauriere M, Lauriere C, Chrispeels MJ, Johnson KD, Sturn A. Characterization of a xylose-specific antiserum that reacts with the complex asparagine-linked glycans of extracellular and vacuolar glycoproteins. Plant Physiol 1989;90:1182-8.
25. Diaz-Perales A, Collada C, Blanco C. Sanchez-Monge R, Carrillo T, Arangoncillo C, et al. Cross-reactions in the latex-fruit syndrome: a relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7.
26. Diaz-Perales A, Sanz ML, Garcia-Casado G, Sanchez-Monge R, Garcia-Selles FJ. Lombardero M, et al. Recombinant Pru p 3 and natural Pru p 3, a major peach allergen, show equivalent immunologic reactivity: a new tool for the diagnosis of fruit allergy. J Allergy Clin Immunol 2003;111:628-33.
27. Chang S, Puryear J, Cairney J. A simple and efficient method for isolating RNA from pine trees. Plant Mol Biol Rep 1993;11:133-6.
28. Saenz de Miera LE, Perez de la Vega M. A comparative study of vicilin genes in Lens: negative evidence of concerted evolution. Mol Biol Evol 1998;15:303-11.
29. Wensing M, Knulst AC, Piersma S, O'Kane F, Knol EF, Koppelman SJ. Patients with anaphylaxis to pea can have peanut allergy caused by cross-reactive IgE to vicilin (Ara h 1). J Allergy Clin Immunol 2003;111:420-4.