The ω-3 fatty acid eicosapentaenoic acid elicits cAMP generation in colonic epithelial cells via a "store-operated" mechanism

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 299, Issue 3, 2010, Pages

  Roy, Jessica ^a   Lefkimmiatis, Konstantinos ^a   Moyer, Mary Pat ^b   Curci, Silvana ^a   Hofer, Aldebaran M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b INCELL ^*  (United States)

Author keywords

Fish oil; Mag fura 2; Polyunsaturated fatty acids; Stromal interaction molecule 1

Indexed keywords

CALCIUM; CYCLIC AMP; FURA 2; G PROTEIN COUPLED RECEPTOR; ICOSAPENTAENOIC ACID; ISOBUTYLMETHYLXANTHINE; STROMAL INTERACTION MOLECULE 1; INOSITOL 1,4,5 TRISPHOSPHATE; MEMBRANE PROTEIN; PHOSPHODIESTERASE INHIBITOR; STIM1 PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; CALCIUM CELL LEVEL; CELL PERMEABILIZATION; COLON MUCOSA; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; INTERNAL REFLECTION FLUORESCENCE MICROSCOPY; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CELL LINE; COLON; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; INTESTINE MUCOSA; METABOLISM;

1-METHYL-3-ISOBUTYLXANTHINE; CALCIUM; CELL LINE; COLON; CYCLIC AMP; EICOSAPENTAENOIC ACID; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; INTESTINAL MUCOSA; MEMBRANE PROTEINS; NEOPLASM PROTEINS; PHOSPHODIESTERASE INHIBITORS;

EID: 77956985478     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00028.2010     Document Type: Article

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