Benzodiazepine modulation of the rat GABAA receptor α4β3γ2L subtype expressed in Xenopus oocytes

Neuropharmacology

Volumn 59, Issue 6, 2010, Pages 527-533

  You, Haitao ^a   Kozuska, Janna L ^a   Paulsen, Isabelle M ^a   Dunn, Susan M J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Alpha4 subunit; Benzodiazepine modulation; Beta3 subunit; GABAA receptor; HEK293 cell expression; Oocyte expression

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4BETA1GAMMA2L; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4BETA2GAMMA2L; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4BETA3GAMMA2L; 4 AMINOBUTYRIC ACID A RECEPTOR BETA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; 5 ISOPROPOXY 4 METHYL BETA CARBOLINE 3 CARBOXYLIC ACID ETHYL ESTER; 6 BENZYLOXY 4 METHOXYMETHYL BETA CARBOLINE 3 CARBOXYLIC ACID ETHYL ESTER; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; BENZODIAZEPINE; DIAZEPAM; FLUMAZENIL; FLUNITRAZEPAM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENTIATION; DRUG PROTEIN BINDING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; MODULATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; XENOPUS;

ANIMALS; BENZODIAZEPINES; DIAZEPAM; FLUNITRAZEPAM; GAMMA-AMINOBUTYRIC ACID; HEK293 CELLS; HUMANS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RECEPTORS, GABA-A; XENOPUS;

EID: 77956941981     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.07.011     Document Type: Article

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