Inhibition of ATP-sensitive potassium channels increases HSV-tk/GCV bystander effect in U373 human glioma cells by enhancing gap junctional intercellular communication

Neuropharmacology

Volumn 59, Issue 6, 2010, Pages 480-491

  Paíno, Teresa ^a   Gangoso, Ester ^a   Medina, José M ^a   Tabernero Arantxa, A ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

CNS; Connexin; Gap junctions; Sulfonylurea; Tolbutamide; Tumor

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CARBENOXOLONE; CONNEXIN 43; GANCICLOVIR; THYMIDINE KINASE; TOLBUTAMIDE;

ARTICLE; BYSTANDER EFFECT; COCULTURE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; GAP JUNCTION; GENE SILENCING; GENETIC TRANSFECTION; GLIOMA CELL; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION;

ANALYSIS OF VARIANCE; BLOTTING, WESTERN; BYSTANDER EFFECT; CELL LINE, TUMOR; CELLS, CULTURED; FLOW CYTOMETRY; GANCICLOVIR; GAP JUNCTIONS; HUMANS; IN SITU NICK-END LABELING; KATP CHANNELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSFECTION; VIRAL PROTEINS;

EID: 77956933006     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.06.011     Document Type: Article

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