Pharmacological modulation of the bystander effect in the herpes simplex virus thymidine kinase/ganciclovir gene therapy system. Effects of dibutyryl adenosine 3',5'-cyclic monophosphate, α-glycyrrhetinic acid, and cytosine arabinoside

Biochemical Pharmacology

Volumn 60, Issue 2, 2000, Pages 241-249

  Robe, Pierre Alain ^a,b   Princen, Frédéric ^a   Martin, Didier ^a   Malgrange, Brigitte ^a   Stevenaert, Achille ^a   Moonen, Gustave ^a   Gielen, Jacques ^a   Merville, Marie Paule ^a   Bours, Vincent ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Bystander effect; Cyclic AMP; Gap junctions; Thymidine kinase

Indexed keywords

BUCLADESINE; CYTARABINE; GANCICLOVIR; GLYCYRRHETINIC ACID; MESSENGER RNA; THYMIDINE KINASE; VIRUS ENZYME;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BYSTANDER EFFECT; CANCER CELL CULTURE; CELL COMMUNICATION; CELL JUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; GENE THERAPY; GENETIC TRANSFECTION; GLIOBLASTOMA; HERPES SIMPLEX VIRUS 1; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BUCLADESINE; CONNEXIN 43; CONNEXINS; CYTARABINE; DRUG SCREENING ASSAYS, ANTITUMOR; GANCICLOVIR; GAP JUNCTIONS; GENE THERAPY; GLIOBLASTOMA; GLYCYRRHETINIC ACID; PHOSPHORYLATION; RATS; RNA, MESSENGER; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034662464     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00315-4     Document Type: Article

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