메뉴 건너뛰기




Volumn 15, Issue 12, 2008, Pages 823-831

Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43

Author keywords

Bystander effect; Connexin43; Ganciclovir; Gap junction; Glioblastoma; Thymidine kinase

Indexed keywords

CONNEXIN 43; GANCICLOVIR; GAP JUNCTION PROTEIN; GLYCYRRHETINIC ACID; SMALL INTERFERING RNA; THYMIDINE KINASE;

EID: 56049092037     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2008.49     Document Type: Article
Times cited : (23)

References (37)
  • 2
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten FL. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986; 46: 5276-5281.
    • (1986) Cancer Res , vol.46 , pp. 5276-5281
    • Moolten, F.L.1
  • 3
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH, Blaese RM. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-1552.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 4
    • 0037832252 scopus 로고    scopus 로고
    • Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: Fifteen years of application
    • Fillat C, Carrio M, Cascante A, Sangro B. Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application. Curr Gene Ther 2003; 3: 13-26.
    • (2003) Curr Gene Ther , vol.3 , pp. 13-26
    • Fillat, C.1    Carrio, M.2    Cascante, A.3    Sangro, B.4
  • 5
    • 0021055765 scopus 로고
    • Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells
    • Cheng YC, Grill SP, Dutschman GE, Nakayama K, Bastow KF. Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells. J Biol Chem 1983; 258: 12460-12464.
    • (1983) J Biol Chem , vol.258 , pp. 12460-12464
    • Cheng, Y.C.1    Grill, S.P.2    Dutschman, G.E.3    Nakayama, K.4    Bastow, K.F.5
  • 6
    • 0027531548 scopus 로고
    • In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats
    • Ram Z, Culver KW, Walbridge S, Blaese RM, Oldfield EH. In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats. Cancer Res 1993; 53: 83-88.
    • (1993) Cancer Res , vol.53 , pp. 83-88
    • Ram, Z.1    Culver, K.W.2    Walbridge, S.3    Blaese, R.M.4    Oldfield, E.H.5
  • 8
    • 0028864786 scopus 로고
    • The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro
    • Fick J, Barker FG, Dazin P, Westphale EM, Beyer EC, Israel MA. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci USA 1995; 92: 11071-11075.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11071-11075
    • Fick, J.1    Barker, F.G.2    Dazin, P.3    Westphale, E.M.4    Beyer, E.C.5    Israel, M.A.6
  • 9
    • 0029996360 scopus 로고    scopus 로고
    • Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins
    • Mesnil M, Piccoli C, Tiraby G, Willecke K, Yamasaki H. Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc Natl Acad Sci USA 1996; 93: 1831-1835.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1831-1835
    • Mesnil, M.1    Piccoli, C.2    Tiraby, G.3    Willecke, K.4    Yamasaki, H.5
  • 10
  • 11
    • 0032408307 scopus 로고    scopus 로고
    • The discovery of metabolic co-operation
    • Pitts JD. The discovery of metabolic co-operation. Bioessays 1998; 20: 1047-1051.
    • (1998) Bioessays , vol.20 , pp. 1047-1051
    • Pitts, J.D.1
  • 12
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird DW. Life cycle of connexins in health and disease. Biochem J 2006; 394: 527-543.
    • (2006) Biochem J , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 14
  • 15
    • 0032967790 scopus 로고    scopus 로고
    • Suppression of human prostate cancer cell growth by forced expression of connexin genes
    • Mehta PP, Perez-Stable C, Nadji M, Mian M, Asotra K, Roos BA. Suppression of human prostate cancer cell growth by forced expression of connexin genes. Dev Genet 1999; 24: 91-110.
    • (1999) Dev Genet , vol.24 , pp. 91-110
    • Mehta, P.P.1    Perez-Stable, C.2    Nadji, M.3    Mian, M.4    Asotra, K.5    Roos, B.A.6
  • 16
    • 28944441155 scopus 로고    scopus 로고
    • Defective gap junctional intercellular communication in the carcinogenic process
    • Mesnil M, Crespin S, Avanzo JL, Zaidan-Dagli ML. Defective gap junctional intercellular communication in the carcinogenic process. Biochim Biophys Acta 2005; 1719: 125-145.
    • (2005) Biochim Biophys Acta , vol.1719 , pp. 125-145
    • Mesnil, M.1    Crespin, S.2    Avanzo, J.L.3    Zaidan-Dagli, M.L.4
  • 17
  • 18
    • 15844409182 scopus 로고    scopus 로고
    • Protein and messenger RNA expression of connexin43 in astrocytomas: Implications in brain tumor gene therapy
    • Shinoura N, Chen L, Wani MA, Kim YG, Larson JJ, Warnick RE et al. Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapy. J Neurosurg 1996; 84: 839-845.
    • (1996) J Neurosurg , vol.84 , pp. 839-845
    • Shinoura, N.1    Chen, L.2    Wani, M.A.3    Kim, Y.G.4    Larson, J.J.5    Warnick, R.E.6
  • 19
    • 0032929652 scopus 로고    scopus 로고
    • Connexins are expressed in primary brain tumors and enhance the bystander effect in gene therapy
    • Estin D, Li M, Spray D, Wu JK. Connexins are expressed in primary brain tumors and enhance the bystander effect in gene therapy. Neurosurgery 1999; 44: 361-368.
    • (1999) Neurosurgery , vol.44 , pp. 361-368
    • Estin, D.1    Li, M.2    Spray, D.3    Wu, J.K.4
  • 20
    • 0034950760 scopus 로고    scopus 로고
    • Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex
    • Aronica E, Gorter JA, Jansen GH, Leenstra S, Yankaya B, Troost D. Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex. Acta Neuropathol (Berl) 2001; 101: 449-459.
    • (2001) Acta Neuropathol (Berl) , vol.101 , pp. 449-459
    • Aronica, E.1    Gorter, J.A.2    Jansen, G.H.3    Leenstra, S.4    Yankaya, B.5    Troost, D.6
  • 21
    • 0347926503 scopus 로고    scopus 로고
    • Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene
    • Asklund T, Appelskog IB, Ammerpohl O, Langmoen IA, Dilber MS, Aints A et al. Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene. Exp Cell Res 2003; 284: 185-195.
    • (2003) Exp Cell Res , vol.284 , pp. 185-195
    • Asklund, T.1    Appelskog, I.B.2    Ammerpohl, O.3    Langmoen, I.A.4    Dilber, M.S.5    Aints, A.6
  • 22
    • 9344252208 scopus 로고    scopus 로고
    • Altered expression of Cx43 in astrocytic tumors
    • Pu P, Xia Z, Yu S, Huang Q. Altered expression of Cx43 in astrocytic tumors. Clin Neurol Neurosurg 2004; 107: 49-54.
    • (2004) Clin Neurol Neurosurg , vol.107 , pp. 49-54
    • Pu, P.1    Xia, Z.2    Yu, S.3    Huang, Q.4
  • 23
    • 0032892110 scopus 로고    scopus 로고
    • Reduced connexin43 expression in high-grade human brain glioma cells
    • Huang RP, Hossain MZ, Sehgal A, Boynton AL. Reduced connexin43 expression in high-grade human brain glioma cells. J Surg Oncol 1999; 70: 21-24.
    • (1999) J Surg Oncol , vol.70 , pp. 21-24
    • Huang, R.P.1    Hossain, M.Z.2    Sehgal, A.3    Boynton, A.L.4
  • 24
    • 0034691509 scopus 로고    scopus 로고
    • Enhanced ganciclovir killing and bystander effect of human tumor cells transduced with a retroviral vector carrying a herpes simplex virus thymidine kinase gene mutant
    • Qiao J, Black ME, Caruso M. Enhanced ganciclovir killing and bystander effect of human tumor cells transduced with a retroviral vector carrying a herpes simplex virus thymidine kinase gene mutant. Hum Gene Ther 2000; 11: 1569-1576.
    • (2000) Hum Gene Ther , vol.11 , pp. 1569-1576
    • Qiao, J.1    Black, M.E.2    Caruso, M.3
  • 25
    • 0037166945 scopus 로고    scopus 로고
    • Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor
    • Hunyady L, Baukal AJ, Gaborik Z, Olivares-Reyes JA, Bor M, Szaszak M et al. Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor. J Cell Biol 2002; 157: 1211-1222.
    • (2002) J Cell Biol , vol.157 , pp. 1211-1222
    • Hunyady, L.1    Baukal, A.J.2    Gaborik, Z.3    Olivares-Reyes, J.A.4    Bor, M.5    Szaszak, M.6
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 28
    • 1942470517 scopus 로고    scopus 로고
    • The effects of connexin phosphorylation on gap junctional communication
    • Lampe PD, Lau AF. The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol 2004; 36: 1171-1186.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1171-1186
    • Lampe, P.D.1    Lau, A.F.2
  • 29
    • 0030042852 scopus 로고    scopus 로고
    • Evidence that disruption of connexon particle arrangements in gap junction plaques is associated with inhibition of gap junctional communication by a glycyrrhetinic acid derivative
    • Goldberg GS, Moreno AP, Bechberger JF, Hearn SS, Shivers RR, MacPhee DJ et al. Evidence that disruption of connexon particle arrangements in gap junction plaques is associated with inhibition of gap junctional communication by a glycyrrhetinic acid derivative. Exp Cell Res 1996; 222: 48-53.
    • (1996) Exp Cell Res , vol.222 , pp. 48-53
    • Goldberg, G.S.1    Moreno, A.P.2    Bechberger, J.F.3    Hearn, S.S.4    Shivers, R.R.5    MacPhee, D.J.6
  • 30
    • 0036873006 scopus 로고    scopus 로고
    • Connexins and cancer
    • Mesnil M. Connexins and cancer. Biol Cell 2002; 94: 493-500.
    • (2002) Biol Cell , vol.94 , pp. 493-500
    • Mesnil, M.1
  • 31
    • 0032505770 scopus 로고    scopus 로고
    • Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation
    • McMasters RA, Saylors RL, Jones KE, Hendrix ME, Moyer MP, Drake RR. Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation. Hum Gene Ther 1998; 9: 2253-2261.
    • (1998) Hum Gene Ther , vol.9 , pp. 2253-2261
    • McMasters, R.A.1    Saylors, R.L.2    Jones, K.E.3    Hendrix, M.E.4    Moyer, M.P.5    Drake, R.R.6
  • 32
    • 0030699933 scopus 로고    scopus 로고
    • Variable efficiency of the thymidine kinase/ganciclovir system in human glioblastoma cell lines: Implications for gene therapy
    • Sturtz FG, Waddell K, Shulok J, Chen X, Caruso M, Sanson M et al. Variable efficiency of the thymidine kinase/ganciclovir system in human glioblastoma cell lines: implications for gene therapy. Hum Gene Ther 1997; 8: 1945-1953.
    • (1997) Hum Gene Ther , vol.8 , pp. 1945-1953
    • Sturtz, F.G.1    Waddell, K.2    Shulok, J.3    Chen, X.4    Caruso, M.5    Sanson, M.6
  • 33
    • 7044235842 scopus 로고    scopus 로고
    • AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: A randomised, controlled study
    • Immonen A, Vapalahti M, Tyynela K, Hurskainen H, Sandmair A, Vanninen R et al. AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol Ther 2004; 10: 967-972.
    • (2004) Mol Ther , vol.10 , pp. 967-972
    • Immonen, A.1    Vapalahti, M.2    Tyynela, K.3    Hurskainen, H.4    Sandmair, A.5    Vanninen, R.6
  • 34
    • 0037047365 scopus 로고    scopus 로고
    • Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication
    • Qin H, Shao Q, Curtis H, Galipeau J, Belliveau DJ, Wang T et al. Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. J Biol Chem 2002; 277: 29132-29138.
    • (2002) J Biol Chem , vol.277 , pp. 29132-29138
    • Qin, H.1    Shao, Q.2    Curtis, H.3    Galipeau, J.4    Belliveau, D.J.5    Wang, T.6
  • 35
    • 0348134730 scopus 로고    scopus 로고
    • Sequestration of connexin43 in the early endosomes: An early event of Leydig cell tumor progression
    • Segretain D, Decrouy X, Dompierre J, Escalier D, Rahman N, Fiorini C et al. Sequestration of connexin43 in the early endosomes: an early event of Leydig cell tumor progression. Mol Carcinog 2003; 38: 179-187.
    • (2003) Mol Carcinog , vol.38 , pp. 179-187
    • Segretain, D.1    Decrouy, X.2    Dompierre, J.3    Escalier, D.4    Rahman, N.5    Fiorini, C.6
  • 36
    • 0029176855 scopus 로고
    • Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells
    • Laird DW, Castillo M, Kasprzak L. Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells. J Cell Biol 1995; 131: 1193-1203.
    • (1995) J Cell Biol , vol.131 , pp. 1193-1203
    • Laird, D.W.1    Castillo, M.2    Kasprzak, L.3
  • 37
    • 1142299407 scopus 로고    scopus 로고
    • Disrupted traffic of connexin 43 in human testicular seminoma cells: Overexpression of Cx43 induces membrane location and cell proliferation decrease
    • Roger C, Mograbi B, Chevallier D, Michiels JF, Tanaka H, Segretain D et al. Disrupted traffic of connexin 43 in human testicular seminoma cells: overexpression of Cx43 induces membrane location and cell proliferation decrease. J Pathol 2004; 202: 241-246.
    • (2004) J Pathol , vol.202 , pp. 241-246
    • Roger, C.1    Mograbi, B.2    Chevallier, D.3    Michiels, J.F.4    Tanaka, H.5    Segretain, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.