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Volumn 27, Issue 2, 2010, Pages 185-198

TNF-α and its inhibitors in cancer

Author keywords

Anti TNF ; Cancer; Inhibitors; Therapy; TNF

Indexed keywords

ADALIMUMAB; CC 3052; CERTOLIZUMAB PEGOL; ETANERCEPT; GOLIMUMAB; IMID; IMMUNOMODULATING AGENT; INFLIXIMAB; LENALIDOMIDE; PHOSPHODIESTERASE INHIBITOR; POMALIDOMIDE; SELCID; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG;

EID: 77956898009     PISSN: 13570560     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12032-009-9190-3     Document Type: Article
Times cited : (89)

References (147)
  • 1
    • 0016723594 scopus 로고
    • An endotoxin-induced serum factor that causes necrosis of tumors
    • USA doi:10.1073/pnas.72.9.3666
    • Carswell E, et al. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA. 1975;72:3666-70. doi:10.1073/pnas.72.9.3666.
    • (1975) Proc Natl Acad Sci , vol.72 , pp. 3666-70
    • Carswell, E.1
  • 2
    • 2142756589 scopus 로고    scopus 로고
    • Anti-TNFalpha therapy of rheumatoid arthritis: What can we learn about chronic disease?
    • doi:10.1002/0470856734.ch5
    • Feldmann M, et al. Anti-TNFalpha therapy of rheumatoid arthritis: what can we learn about chronic disease? Novartis Found Symp. 2004;256:53-69. doi:10.1002/0470856734.ch5.
    • (2004) Novartis Found Symp , vol.256 , pp. 53-69
    • Feldmann, M.1
  • 3
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • DOI 10.1016/S0092-8674(01)00237-9
    • Locksley R, Killeen N, Lenardo M. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 2001;104: 487-501. doi:10.1016/S0092- 8674(01)00237-9. (Pubitemid 32201945)
    • (2001) Cell , vol.104 , Issue.4 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 5
    • 0029114596 scopus 로고
    • Two tumour necrosis factor receptors: Structure and function
    • doi:10.1016/S0962-8924(00)89088-1
    • Vandenabeele P, Declercq W, Beyaert R, Fiers W. Two tumour necrosis factor receptors: structure and function. Trends Cell Biol. 1995;5:392-9. doi:10.1016/S0962-8924(00)89088-1.
    • (1995) Trends Cell Biol , vol.5 , pp. 392-399
    • Vandenabeele, P.1    Declercq, W.2    Beyaert, R.3    Fiers, W.4
  • 6
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • DOI 10.1056/NEJM199606273342607
    • Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med. 1996;334:1717-25. doi:10. 1056/NEJM199606273342607. (Pubitemid 26193625)
    • (1996) New England Journal of Medicine , vol.334 , Issue.26 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 7
    • 85047692516 scopus 로고    scopus 로고
    • Signalling pathways of the TNF superfamily: A double-edged sword
    • doi: 10.1038/nri1184
    • Aggarwal B. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol. 2003;3:745-56. doi: 10.1038/nri1184.
    • (2003) Nat Rev Immunol , vol.3 , pp. 745-756
    • Aggarwal, B.1
  • 8
    • 0026514526 scopus 로고
    • Two TNF receptors
    • doi:10.1016/0167-5699(92)90116-O
    • Tartaglia L, Goeddel D. Two TNF receptors. Immunol Today. 1992;13:151-3. doi:10.1016/0167-5699(92)90116-O.
    • (1992) Immunol Today , vol.13 , pp. 151-153
    • Tartaglia, L.1    Goeddel, D.2
  • 9
    • 1342285692 scopus 로고    scopus 로고
    • Tumor Necrosis Factor: An Apoptosis JuNKie?
    • DOI 10.1016/S0092-8674(04)00166-7
    • Varfolomeev EE, Ashkenazi A. Tumor necrosis factor: an apoptosis JuNKie? Cell. 2004;116:491-7. doi:10.1016/S0092-8674(04)00166-7. (Pubitemid 38264427)
    • (2004) Cell , vol.116 , Issue.4 , pp. 491-497
    • Varfolomeev, E.E.1    Ashkenazi, A.2
  • 10
    • 44749093460 scopus 로고    scopus 로고
    • Ubiquitin-mediated regulation of TNFR1 signaling
    • doi: 10.1016/j.cytogfr.2008.04.014
    • Wertz IE, Dixit VM. Ubiquitin-mediated regulation of TNFR1 signaling. Cytokine Growth Factor Rev. 2008;19:313-24. doi: 10.1016/j.cytogfr.2008.04.014.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 313-324
    • Wertz, I.E.1    Dixit, V.M.2
  • 11
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • DOI 10.1126/science.1071924
    • Chen G, Goeddel D. TNF-R1 signaling: a beautiful pathway. Science. 2002;296:1634-5. doi:10.1126/science.1071924. (Pubitemid 34579145)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 12
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • DOI 10.1038/ncb0805-758
    • Chen ZJ. Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol. 2005;7:758-65. doi:10.1038/ncb0805-758. (Pubitemid 41079044)
    • (2005) Nature Cell Biology , vol.7 , Issue.8 , pp. 758-765
    • Chen, Z.J.1
  • 13
    • 44749088134 scopus 로고    scopus 로고
    • Crosstalk via the NF-kappa B signaling system
    • doi: 10.1016/j.cytogfr.2008.04.005
    • Basak S, Hoffmann A. Crosstalk via the NF-kappa B signaling system. Cytokine Growth Factor Rev. 2008;19:187-97. doi: 10.1016/j.cytogfr.2008.04.005.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 187-197
    • Basak, S.1    Hoffmann, A.2
  • 14
    • 0024503589 scopus 로고
    • Prolonged activation of JUN and collagenase genes by tumour necrosis factor-alpha
    • doi:10.1038/337 661a0
    • Brenner DA, O'Hara M, Angel P, Chojkier M, Karin M. Prolonged activation of JUN and collagenase genes by tumour necrosis factor-alpha. Nature. 1989;337:661-3. doi:10.1038/337 661a0.
    • (1989) Nature , vol.337 , pp. 661-663
    • Brenner, D.A.1    O'hara, M.2    Angel, P.3    Chojkier, M.4    Karin, M.5
  • 15
    • 5644222552 scopus 로고    scopus 로고
    • Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
    • doi:10.1016/ j.immuni.2004. 10.001
    • Muppidi JR, Tschopp J, Siegl RM. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity. 2004;21:461-5. doi:10.1016/ j.immuni.2004.10.001.
    • (2004) Immunity , vol.21 , pp. 461-465
    • Muppidi, J.R.1    Tschopp, J.2    Siegl, R.M.3
  • 16
    • 41049112098 scopus 로고    scopus 로고
    • TRAIL and cancer therapy
    • doi:10.1016/j.canlet.2008.02.003
    • Kruyt FAE. TRAIL and cancer therapy. Cancer Lett. 2008;263:14-25. doi:10.1016/j.canlet.2008.02.003.
    • (2008) Cancer Lett , vol.263 , pp. 14-25
    • Kruyt, F.A.E.1
  • 17
    • 3342968806 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha in the pathogenesis and treatment of cancer
    • DOI 10.1016/j.coph.2004.04.004, PII S1471489204000943
    • Anderson G, Nakada MT, DeWitte M. Tumor necrosis factoralpha in the pathogenesis and treatment of cancer. Curr Opin Pharmacol. 2004;4:314-20. doi:10.1016/j.coph.2004.04.004. (Pubitemid 38987055)
    • (2004) Current Opinion in Pharmacology , vol.4 , Issue.4 , pp. 314-320
    • Anderson, G.M.1    Nakada, M.T.2    DeWitte, M.3
  • 18
    • 0037644804 scopus 로고    scopus 로고
    • Biological functions of tumor necrosis factor cytokines and their receptors
    • DOI 10.1016/S1359-6101(03)00022-4
    • Pfeffer K. Biological functions of tumor necrosis factor cytokines and their receptors. Cytokine Growth Factor Rev. 2003;14:185-91. doi:10.1016/S1359-6101(03)00022-4. (Pubitemid 36693140)
    • (2003) Cytokine and Growth Factor Reviews , vol.14 , Issue.3-4 , pp. 185-191
    • Pfeffer, K.1
  • 19
    • 44749088915 scopus 로고    scopus 로고
    • Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: Mouse models
    • doi:10.1016/j.cytogfr.2008.04.010
    • Kruglov A, et al. Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models. Cytokine Growth Factor Rev. 2008;19:231-44. doi:10.1016/j.cytogfr.2008.04.010.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 231-244
    • Kruglov, A.1
  • 20
    • 0034254453 scopus 로고    scopus 로고
    • TNFalpha and the TNF receptor superfamily: Structure-function relationship(s)
    • DOI 10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H
    • Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000;50:184-95. doi:10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H. (Pubitemid 30610095)
    • (2000) Microscopy Research and Technique , vol.50 , Issue.3 , pp. 184-195
    • Idriss, H.T.1    Naismith, J.H.2
  • 21
    • 39749167232 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha antagonists and neuropathy
    • DOI 10.1002/mus.20924
    • Stübgen J-P. Tumor necrosis factor-alpha antagonists and neuropathy. Muscle Nerve. 2008;37:281-92. doi:10.1002/mus.20924. (Pubitemid 351304787)
    • (2008) Muscle and Nerve , vol.37 , Issue.3 , pp. 281-292
    • Stubgen, J.-P.1
  • 23
    • 23944435859 scopus 로고    scopus 로고
    • The therapeutic potential of tumor necrosis factor for autoimmune disease: A mechanistically based hypothesis
    • DOI 10.1007/s00018-005-5022-6
    • Kodama S, Davis M, Faustman D. The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis. Cell Mol Life Sci. 2005;62:1850-62. doi: 10.1007/s00018-005-5022-6. (Pubitemid 41188524)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.16 , pp. 1850-1862
    • Kodama, S.1    Davis, M.2    Faustman, D.L.3
  • 24
    • 51649084550 scopus 로고    scopus 로고
    • Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism
    • USA, doi:10.1073/pnas.0803429105
    • Ban L, et al. Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism. Proc Natl Acad Sci USA. 2008;105:13644-9. doi:10.1073/pnas.0803429105.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 13644-13649
    • Ban, L.1
  • 26
    • 0037627840 scopus 로고    scopus 로고
    • Ten Hagen T. Current uses of isolated limb perfusion in the clinic and a model system for new strategies
    • doi:10.1016/S1470-2045 (03)01141-0
    • Eggermont A, de Wilt J, ten Hagen T. Current uses of isolated limb perfusion in the clinic and a model system for new strategies. Lancet Oncol. 2003;4:429-37. doi:10.1016/S1470-2045 (03)01141-0.
    • (2003) Lancet Oncol , vol.4 , pp. 429-437
    • Eggermont, A.1    De Wilt, J.2
  • 27
    • 0036678474 scopus 로고    scopus 로고
    • Improving the response of tumors to chemotherapy in mice by targeted delivery of picogram doses of tumor necrosis factor-alpha to tumor vessels
    • Curnis F, Sacchi A, Corti A. Improving the response of tumors to chemotherapy in mice by targeted delivery of picogram doses of tumor necrosis factor-alpha to tumor vessels. J Clin Invest.2002;110:475-82.
    • (2002) J Clin Invest , vol.110 , pp. 475-482
    • Curnis, F.1    Sacchi, A.2    Corti, A.3
  • 28
    • 0027467414 scopus 로고
    • Tumor-necrosis factor can enhance radio-antibody uptake in human colon carcinoma xenografts by increasing vascular permeability
    • doi:10. 1002/ijc.2910530521
    • Folli S, et al. Tumor-necrosis factor can enhance radio-antibody uptake in human colon carcinoma xenografts by increasing vascular permeability. Int J Cancer. 1993;53:829-36. doi:10. 1002/ijc.2910530521.
    • (1993) Int J Cancer , vol.53 , pp. 829-836
    • Folli, S.1
  • 29
    • 33645782015 scopus 로고    scopus 로고
    • TNF-alpha in cancer treatment: Molecular insights, antitumor effects, and clinical utility
    • doi:10.1634/theo ncologist.11-4-397
    • van Horssen R, Ten Hagen T, Eggermont A. TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility. Oncologist. 2006;11:397-408. doi:10.1634/theo ncologist.11-4-397.
    • (2006) Oncologist , vol.11 , pp. 397-408
    • Van Horssen, R.1    Ten Hagen, T.2    Eggermont, A.3
  • 30
    • 41149083660 scopus 로고    scopus 로고
    • Tumor necrosis factor-mediated interactions between inflammatory response and tumor vascular bed
    • doi:10. 1111/j.1600-065X.2008.00619.x
    • ten Hagen T, Seynhaeve A, Eggermont A. Tumor necrosis factor-mediated interactions between inflammatory response and tumor vascular bed. Immunol Rev. 2008;222:299-315. doi:10. 1111/j.1600-065X.2008.00619.x.
    • (2008) Immunol Rev , vol.222 , pp. 299-315
    • Ten Hagen, T.1    Seynhaeve, A.2    Eggermont, A.3
  • 31
    • 0030058843 scopus 로고    scopus 로고
    • Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: Results of a tumor necrosis factor doseescalation study
    • Fraker DL, Alexander H, Andrich M, Rosenberg S. Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor doseescalation study. J Clin Oncol. 1996;14:479-89.
    • (1996) J Clin Oncol , vol.14 , pp. 479-489
    • Fraker, D.L.1    Alexander, H.2    Andrich, M.3    Rosenberg, S.4
  • 32
    • 33645782015 scopus 로고    scopus 로고
    • TNF-alpha in Cancer Treatment: Molecular Insights Antitumor Effects and Clinical Utility
    • doi:10.1634/ theoncologist.11-4-397
    • Van Horssen R, Ten Hagen TLM, Eggermont AMM. TNF-alpha in Cancer Treatment: Molecular Insights, Antitumor Effects, and Clinical Utility. The Oncologist. 2006;11:397-408. doi:10.1634/ theoncologist.11-4-397.
    • (2006) The Oncologist , vol.11 , pp. 397-408
    • Van Horssen, R.1    Ten Hagen, T.L.M.2    Eggermont, A.M.M.3
  • 33
    • 33748869716 scopus 로고    scopus 로고
    • Recombinant human tumor necrosis factor: An efficient agent for cancer treatment
    • Lejeune F, Rüegg C. Recombinant human tumor necrosis factor:an efficient agent for cancer treatment. Bull Cancer. 2006;93: E90-100.
    • (2006) Bull Cancer , vol.93
    • Lejeune, F.1    Rüegg, C.2
  • 35
    • 0345596439 scopus 로고    scopus 로고
    • Isolated hepatic perfusion with tumornecrosis factor and melphalan for unresectable cancers confined to the liver
    • Alexander HJ, et al. Isolated hepatic perfusion with tumornecrosis factor and melphalan for unresectable cancers confined to the liver. J Clin Oncol. 1998;16:1479-89.
    • (1998) J Clin Oncol , vol.16 , pp. 1479-1489
    • Alexander, H.J.1
  • 36
    • 10744221996 scopus 로고    scopus 로고
    • Selective targeted delivery of TNF alpha to tumor blood vessels
    • doi:10.1182/blood- 2003-04-1039
    • Borsi L, et al. Selective targeted delivery of TNF alpha to tumor blood vessels. Blood. 2003;102:4384-92. doi:10.1182/blood- 2003-04-1039.
    • (2003) Blood , vol.102 , pp. 4384-4392
    • Borsi, L.1
  • 37
    • 14944353793 scopus 로고    scopus 로고
    • Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs
    • DOI 10.1196/annals.1322.011
    • Corti A, Ponzoni M. Tumor vascular targeting with tumornecrosis factor alpha and chemotherapeutic drugs. Ann NY Acad Sci. 2004;1028:104-12. doi:10.1196/annals.1322.011. (Pubitemid 40361814)
    • (2004) Annals of the New York Academy of Sciences , vol.1028 , pp. 104-112
    • Corti, A.1    Ponzoni, M.2
  • 41
    • 0032199393 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer
    • Chung T, et al. Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer. Cancer Gene Ther. 1998;5:344-9.
    • (1998) Cancer Gene Ther , vol.5 , pp. 344-349
    • Chung, T.1
  • 42
    • 0031951530 scopus 로고    scopus 로고
    • Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft
    • doi:10.1038/sj.gt.3300594
    • Staba M, Mauceru H, Kufe D, Hallahan D, Weichselbaum R. Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther. 1998;5:293-300. doi:10.1038/sj.gt. 3300594.
    • (1998) Gene Ther , vol.5 , pp. 293-300
    • Staba, M.1    Mauceru, H.2    Kufe, D.3    Hallahan, D.4    Weichselbaum, R.5
  • 43
    • 25144471132 scopus 로고    scopus 로고
    • TNFerade, an adenovector carrying the transgene for human tumor necrosis factor alpha, for patients with advanced solid tumors: Surgical experience and long-term follow-up
    • DOI 10.1245/ASO.2005.03.023
    • McLoughlin JM, et al. TNFerade, an adenovector carrying the transgene for human tumor necrosis factor a, for patients with advanced solid tumors: surgical experience and long-term follow-up. Ann Surg Oncol. 2005;12:825-30. doi:10.1245/ASO.2005.03.023. (Pubitemid 41355935)
    • (2005) Annals of Surgical Oncology , vol.12 , Issue.10 , pp. 825-830
    • McLoughlin, J.M.1    McCarty, T.M.2    Cunningham, C.3    Clark, V.4    Senzer, N.5    Nemunaitis, J.6    Kuhn, J.A.7
  • 44
    • 0025806563 scopus 로고
    • Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors
    • Asher AL, et al. Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors. J Immunol. 1991;146:3227-34.
    • (1991) J Immunol , vol.146 , pp. 3227-3234
    • Asher, A.L.1
  • 45
    • 0028504791 scopus 로고
    • Suppression of in vivotumorigenicity of human lung cancer cells by retrovirus-mediated transfer of the human tumor necrosis factor-alpha cDNA
    • Han SK, Brody SL, Crystal RG. Suppression of in vivotumorigenicity of human lung cancer cells by retrovirus-mediated transfer of the human tumor necrosis factor-alpha cDNA. Am J Respir Cell Mol Biol. 1994;11:270-8.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 270-278
    • Han, S.K.1    Brody, S.L.2    Crystal, R.G.3
  • 46
    • 17444368010 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-mediated tumor regression by the in vivo transfer of genes into the artery that leads to tumors
    • Mizuguchi H, et al. Tumor necrosis factor alpha-mediated tumor regression by the in vivo transfer of genes into the artery that leads to tumors. Cancer Res. 1998;58:5727-30.
    • (1998) Cancer Res , vol.58 , pp. 5727-5730
    • Mizuguchi, H.1
  • 47
    • 34249985573 scopus 로고    scopus 로고
    • The inhibition of TNF-alpha anti-tumoral properties by blocking antibodies promotes tumor growth in a rat model
    • doi:10.1016/ j.yexcr.2007.03.027
    • Larmonier N, et al. The inhibition of TNF-alpha anti-tumoral properties by blocking antibodies promotes tumor growth in a rat model. Exp Cell Res. 2007;313:2345-55. doi:10.1016/ j.yexcr.2007.03.027.
    • (2007) Exp Cell Res , vol.313 , pp. 2345-2355
    • Larmonier, N.1
  • 48
    • 18544367202 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha in Barrett's oesophagus: A potential novel mechanism of action
    • doi:10.1038/sj.onc.1205731
    • Tselepsis C, et al. Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action. Oncogene. 2002;21:6071-81. doi:10.1038/sj.onc.1205731.
    • (2002) Oncogene , vol.21 , pp. 6071-6081
    • Tselepsis, C.1
  • 49
    • 0043125501 scopus 로고    scopus 로고
    • Serum and cyst fluid levels of interleukin (IL) -6, IL-8 and tumour necrosis factor-alpha in women with endometriomas and benign and malignant cystic ovarian tumours
    • DOI 10.1093/humrep/deg321
    • Darai E, Detchev R, Hugol D, Quang NT. Serum and cyst fluid levels of interleukin (IL)-6, IL-8 and tumour necrosis factor alpha in women with endometriomas and benign and malignant cycstic ovarian tumours. Hum Reprod. 2003;18:1681-5. doi: 10.1093/humrep/deg321. (Pubitemid 36958050)
    • (2003) Human Reproduction , vol.18 , Issue.8 , pp. 1681-1685
    • Darai, E.1    Detchev, R.2    Hugol, D.3    Quang, N.T.4
  • 50
    • 33646472252 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha as a tumour promoter
    • doi:10.1016/j.ejca.2006.01.012
    • Szlosarek PW, Charles KA, Balkwill FR. Tumour necrosis factor-alpha as a tumour promoter. Eur J Cancer. 2006;42:745-50. doi:10.1016/j.ejca.2006.01.012.
    • (2006) Eur J Cancer , vol.42 , pp. 745-750
    • Szlosarek, P.W.1    Charles, K.A.2    Balkwill, F.R.3
  • 51
    • 0036005888 scopus 로고    scopus 로고
    • Tumor necrosis factor or tumor promoting factor?
    • doi:10.1016/ S1359-6101(01)00020-X
    • Balkwill F. Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev. 2002;13:135-41. doi:10.1016/ S1359-6101(01)00020-X.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 135-141
    • Balkwill, F.1
  • 53
    • 33746853452 scopus 로고    scopus 로고
    • Involvement of the TNF-alpha autocrine-paracrine loop, via NF-kappaB and YY1, in the regulation of tumor cell resistance to Fas-induced apoptosis
    • DOI 10.1016/j.clim.2006.03.015, PII S1521661606001173
    • Huerta-Yepez SM, Vega M, Garban H, Bonavida B. Involvement of the TNF-alpha autocrine-paracrine loop via NF-kappaB and YY1, in the regulation of tumor cell resistance to Fasinduced apoptosis. Clin Immunol. 2006;120:297-309. doi: 10.1016/j.clim.2006.03.015. (Pubitemid 44175895)
    • (2006) Clinical Immunology , vol.120 , Issue.3 , pp. 297-309
    • Huerta-Yepez, S.1    Vega, M.2    Garban, H.3    Bonavida, B.4
  • 54
    • 14044261093 scopus 로고    scopus 로고
    • Tumor necrosis factor, cancer and anticancer therapy
    • DOI 10.1016/j.cytogfr.2004.11.001
    • Mocellin S, Riccardo Rossi C, Pilati P, Nitti D. Tumor necrosis factor, cancer and anticancer therapy. Cytokine Growth Factor Rev. 2005;16:35-53. doi:10.1016/j.cytogfr.2004.11.001. (Pubitemid 40279116)
    • (2005) Cytokine and Growth Factor Reviews , vol.16 , Issue.1 , pp. 35-53
    • Mocellin, S.1    Rossi, C.R.2    Pilati, P.3    Nitti, D.4
  • 55
    • 3342904989 scopus 로고    scopus 로고
    • Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases
    • DOI 10.1093/carcin/bgh146
    • Hagemann T, et al. Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases. Carcinogenesis. 2004;25:1543-9. doi:10.1093/carcin/ bgh146. (Pubitemid 39162720)
    • (2004) Carcinogenesis , vol.25 , Issue.8 , pp. 1543-1549
    • Hagemann, T.1    Robinson, S.C.2    Schulz, M.3    Trumper, L.4    Balkwill, F.R.5    Binder, C.6
  • 57
    • 33644545381 scopus 로고    scopus 로고
    • Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
    • DOI 10.1038/nrc1821, PII N1821
    • Overall CM, Kleifeld O. Tumour microenvironment-opinion: validating matrix metalloproteinases as drug targets and antitargets for cancer therapy. Nat Rev Cancer. 2006;6:227-39. doi:10.1038/nrc1821. (Pubitemid 43292566)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.3 , pp. 227-239
    • Overall, C.M.1    Kleifeld, O.2
  • 59
    • 0031660472 scopus 로고    scopus 로고
    • Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF)
    • Leber TM, Balkwill FR. Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF). Br J Cancer. 1998;78:724-32.
    • (1998) Br J Cancer , vol.78 , pp. 724-732
    • Leber, T.M.1    Balkwill, F.R.2
  • 60
    • 0141431027 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha: A potential target for the therapy of solid tumours
    • DOI 10.1016/S1470-2045(03)01196-3, PII S1470204503011963
    • Szlosarek PW, Balkwill FR. Tumour necrosis factor: a potential target for the therapy of solid tumours. Lancet Oncol. 2003;4:565-73. doi:10.1016/S1470- 2045(03)01196-3. (Pubitemid 38351714)
    • (2003) Lancet Oncology , vol.4 , Issue.9 , pp. 565-573
    • Szlosarek, P.W.1    Balkwill, F.R.2
  • 61
    • 33751285415 scopus 로고    scopus 로고
    • Increase in HLA-G1 proteolytic shedding by tumor cells: A regulatory pathway controlled by NF-kappaB inducers
    • doi:10.1007/s00018- 006-6341-y
    • Zidi I, et al. Increase in HLA-G1 proteolytic shedding by tumor cells: a regulatory pathway controlled by NF-kappaB inducers. Cell Mol Life Sci. 2006;63:2669-81. doi:10.1007/s00018- 006-6341-y.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2669-2681
    • Zidi, I.1
  • 62
    • 0035837652 scopus 로고    scopus 로고
    • The -238 tumor necrosis factor-alpha promoterpolymorphism is associated with decreased susceptibility to cancers
    • doi:10.1016/S0304-3835 (01)00438-4
    • Jang W, et al. The -238 tumor necrosis factor-alpha promoterpolymorphism is associated with decreased susceptibility to cancers. Cancer Lett. 2001;166:41-6. doi:10.1016/S0304-3835 (01)00438-4.
    • (2001) Cancer Lett , vol.166 , pp. 41-46
    • Jang, W.1
  • 64
    • 0141990968 scopus 로고    scopus 로고
    • Polymorphisms in tumour necrosis factor (TNF) are associated with risk of bladder cancer and grade of tumour at presentation
    • doi:10.1038/ sj.bjc.6601165
    • Marsh H, et al. Polymorphisms in tumour necrosis factor (TNF) are associated with risk of bladder cancer and grade of tumour at presentation. Br J Cancer. 2003;89:1096-101. doi:10.1038/ sj.bjc.6601165.
    • (2003) Br J Cancer , vol.89 , pp. 1096-1101
    • Marsh, H.1
  • 65
    • 0029004771 scopus 로고
    • Ghrayeb J.Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions
    • doi:10.1006/cyto.1995.0029
    • Scallon BJ, Arevalo Moore M, Trinh H, Knight DM, Ghrayeb J.Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokine. 1995;7:251-9. doi:10.1006/cyto.1995.0029.
    • (1995) Cytokine , vol.7 , pp. 251-259
    • Scallon, B.J.1    Arevalo Moore, M.2    Trinh, H.3    Knight, D.M.4
  • 66
    • 43949126520 scopus 로고    scopus 로고
    • Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor alpha-expressing cells: Comparison among infliximab, etanercept, and adalimumab
    • DOI 10.1002/art.23447
    • Mitoma H, et al. Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factoralpha expressing cells comparison among Infliximab, Etanercept,and Adalimumab. Arthritis Rheum. 2008;58:1248-57. doi:10.1002/art.23447. (Pubitemid 351705913)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.5 , pp. 1248-1257
    • Mitoma, H.1    Horiuchi, T.2    Tsukamoto, H.3    Tamimoto, Y.4    Kimoto, Y.5    Uchino, A.6    To, K.7    Harashima, S.-I.8    Hatta, N.9    Harada, M.10
  • 67
    • 77956935261 scopus 로고    scopus 로고
    • Humoral immunotherapy and the use of monoclonal antibodies
    • Degos L, LDC, Löwenberg B, editors. Textbook of malignant haematology
    • Daniel PT, Pezzuto A, Dörken B. Humoral immunotherapy and the use of monoclonal antibodies. In: Degos L, LDC, Löwenberg B, editors. Textbook of malignant haematology. Martin Dunitz; 1999, p. 425-46.
    • (1999) Martin Dunitz , pp. 425-46
    • Daniel, P.T.1    Pezzuto, A.2    Dörken, B.3
  • 68
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
    • doi:10.1016/ j.pharmthera.2007.10.001
    • Tracey D, Klareskog L, Sasso EH, Salfled Jg, Tak PP. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther. 2008;117:244-79. doi:10.1016/ j.pharmthera.2007.10.001.
    • (2008) Pharmacol Ther , vol.117 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3    Jg, S.4    Tak, P.P.5
  • 69
    • 33846090262 scopus 로고    scopus 로고
    • Retention rates of tumor necrosis factor blockers in daily practice in 770 rheumatic patients
    • Duclos M, et al. Retention rates of tumor necrosis factor blockers in daily practice in 770 rheumatic patients. J Rheumatol. 2006;33:2433-8.
    • (2006) J Rheumatol , vol.33 , pp. 2433-2438
    • Duclos, M.1
  • 70
    • 39449132386 scopus 로고    scopus 로고
    • The comparative one-year performance of anti-turmor necrosis factor alpha drugs in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: Results from a longitudinal, observational, multicenter study
    • DOI 10.1002/art.23333
    • Schrumpf Heiberg M, et al. The comparative one-year performance of anti-tumor necrosis factor alpha drugs in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: results from a longitudinal, observational, multicenter study. Arthritis Rheum. 2008;59:234-40. doi:10.1002/art.23333. (Pubitemid 351272960)
    • (2008) Arthritis Care and Research , vol.59 , Issue.2 , pp. 234-240
    • Heiberg, M.S.1    Koldingsnes, W.2    Mikkelsen, K.3    Rodevand, E.4    Kaufmann, C.5    Mowinckel, P.6    Kvien, T.K.7
  • 72
    • 34147219117 scopus 로고    scopus 로고
    • Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis: Data from the Spanish registry BIOBADASER
    • doi:10.1186/ar1941
    • Carmona L, Gomez-Reino JJS, Group B. Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis: data from the Spanish registry BIOBADASER.Arthritis Res Ther. 2006;8:R72. doi:10.1186/ar1941.
    • (2006) Arthritis Res Ther , vol.8
    • Carmona, L.1    Jjs, G.2    Group, B.3
  • 73
    • 36749002002 scopus 로고    scopus 로고
    • Impact of concomitant DMARD therapy on adherence to treatment with Etanercept and Infliximab in rheumatoid arthritis: Results from a six-year observational study in southern Sweden
    • doi:10.1186/ar2084
    • Kristensen LE, Saxne T, Nilsson JA, Geborek P. Impact of concomitant DMARD therapy on adherence to treatment with Etanercept and Infliximab in rheumatoid arthritis: results from a six-year observational study in southern Sweden. Arthritis Res Ther. 2006;8:R174. doi:10.1186/ar2084.
    • (2006) Arthritis Res Ther , vol.8
    • Kristensen, L.E.1    Saxne, T.2    Nilsson, J.A.3    Geborek, P.4
  • 74
    • 0033639123 scopus 로고    scopus 로고
    • Clinical experience with infliximab therapy in 100 patients with Crohn's disease
    • doi:10.1111/j.1572-0241.2000.03366.x
    • Farrell R, et al. Clinical experience with infliximab therapy in 100 patients with Crohn's disease. Am J Gastroenterol. 2000;95:3490-7. doi:10.1111/j.1572-0241.2000.03366.x.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3490-3497
    • Farrell, R.1
  • 77
    • 0000062952 scopus 로고    scopus 로고
    • Lnfliximab treatment benefits correlate with pbarmacodynamic parameters in Crohn's disease patients
    • Wagner C, et al. lnfliximab treatment benefits correlate with pbarmacodynamic parameters in Crohn's disease patients. Digestion. 1998;59:124-5.
    • (1998) Digestion , vol.59 , pp. 124-125
    • Wagner, C.1
  • 78
    • 0031771280 scopus 로고    scopus 로고
    • Neutralization of TNF by the antibody cA2 reveals differential regulation of adhesion molecule expression on TNF-activated endothelial cells
    • doi:10.3109/15419069809005606
    • Nakada M, et al. Neutralization of TNF by the antibody cA2 reveals differential regulation of adhesion molecule expression on TNF-activated endothelial cells. Cell Adhes Commun.1998;5:491-503. doi:10.3109/ 15419069809005606.
    • (1998) Cell Adhes Commun , vol.5 , pp. 491-503
    • Nakada, M.1
  • 79
    • 0033125226 scopus 로고    scopus 로고
    • Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
    • Sandborn WJ, Hanauer SB. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm Bowel Dis. 1999;5:119-33.
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 119-133
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 80
    • 3543058090 scopus 로고    scopus 로고
    • Beneficial effect of treatment with a monoclonal anti-tumor necrosis factor-alpha antibody on markers of coagulation and fibrinolysis in patients with active Crohn's disease
    • Hommes D, et al. Beneficial effect of treatment with a monoclonal anti-tumor necrosis factor-alpha antibody on markers of coagulation and fibrinolysis in patients with active Crohn's disease. Haemostasis. 1997;27:269-77
    • (1997) Haemostasis , vol.27 , pp. 269-277
    • Hommes, D.1
  • 81
    • 0031762451 scopus 로고    scopus 로고
    • Reduction of circulating secretory phospholipase A, levels by anti-tumor necrosis factor chimeric monoclonal antibody in patients with severe Crohn's disease. Relation between tumor necrosis factor and secretory phospholipase A, in healthy humans and active Crohn's disease
    • doi:10.1080/003655298 750026813
    • Van Dullemen H, et al. Reduction of circulating secretory phospholipase A, levels by anti-tumor necrosis factor chimeric monoclonal antibody in patients with severe Crohn's disease. Relation between tumor necrosis factor and secretory phospholipase A, in healthy humans and active Crohn's disease. Scand J Gastroenterol. 1998;33:1094-8. doi:10.1080/003655298 750026813.
    • (1998) Scand J Gastroenterol , vol.33 , pp. 1094-1098
    • Van Dullemen, H.1
  • 82
    • 36248943548 scopus 로고    scopus 로고
    • Biothérapies et MICI : anti-TNF et nouvelles cibles thérapeutiques
    • DOI 10.1016/j.revmed.2007.06.008, PII S024886630700625X
    • Flamant M, Bourreille A. Biothe'rapies et MICI: anti-TNF et nouvelles cibles the'rapeutiques Biologic therapies in inflammatory bowel disease. Rev Med Interne. 2007;28:852-61. doi: 10.1016/j.revmed.2007.06.008. (Pubitemid 350122795)
    • (2007) Revue de Medecine Interne , vol.28 , Issue.12 , pp. 852-861
    • Flamant, M.1    Bourreille, A.2
  • 87
    • 2542474187 scopus 로고    scopus 로고
    • Adalimumab therapy in rheumatoid arthritis
    • DOI 10.1016/j.rdc.2004.02.004, PII S0889857X04000286
    • Keystone E, Haraoui B. Adalimumab therapy in rheumatoid arthritis. Rheum Dis Clin North Am. 2004;30:349-64. doi: 10.1016/j.rdc.2004.02.004. (Pubitemid 38692566)
    • (2004) Rheumatic Disease Clinics of North America , vol.30 , Issue.2 , pp. 349-364
    • Keystone, E.1    Haraoui, B.2
  • 88
    • 34547115206 scopus 로고    scopus 로고
    • Effects of an anti-TNF-alpha monoclonal antibody, administered throughout pregnancy and lactation, on the development of the Macaque immune system
    • doi:10.1111/j.1600- 0897.2007.00499.x
    • Martin PL, Oneda S, Treacy G. Effects of an anti-TNF-alpha monoclonal antibody, administered throughout pregnancy and lactation, on the development of the Macaque immune system. Am J Reprod Immunol. 2007;58:138-49. doi:10.1111/j.1600- 0897.2007.00499.x.
    • (2007) Am J Reprod Immunol , vol.58 , pp. 138-149
    • Martin, P.L.1    Oneda, S.2    Treacy, G.3
  • 91
    • 55849108826 scopus 로고    scopus 로고
    • Efficacy and safety of Golimumab in patients with ankylosing spondylitis results of a randomized, doubleblind, placebo-controlled, phase III trial
    • doi:10.1002/art.23969
    • Inman RD, et al. Efficacy and safety of Golimumab in patients with ankylosing spondylitis results of a randomized, doubleblind, placebo-controlled, phase III trial. Arthritis Rheum. 2008;58:3402-12. doi:10.1002/art.23969.
    • (2008) Arthritis Rheum , vol.58 , pp. 3402-3412
    • Inman, R.D.1
  • 92
    • 49249123639 scopus 로고    scopus 로고
    • Golimumab, a fully human monoclonal antibody against TNF-alpha
    • Hutas G. Golimumab, a fully human monoclonal antibody against TNF-alpha. Curr Opin Mol Ther. 2008;10:393-406.
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 393-406
    • Hutas, G.1
  • 93
    • 34447523749 scopus 로고    scopus 로고
    • Certolizumab pegol for the treatment of Crohn's disease
    • doi:10. 1056/NEJMoa067594
    • Sandborn WJ, et al. Certolizumab pegol for the treatment of Crohn's disease. N Engl J Med. 2007;357:228-38. doi:10. 1056/NEJMoa067594.
    • (2007) N Engl J Med , vol.357 , pp. 228-238
    • Sandborn, W.J.1
  • 95
    • 0027255950 scopus 로고
    • Humanized antibodies
    • DOI 10.1016/0167-5699(93)90039-N
    • Winter G, Harris W. Humanized antibodies. Immunol Today. 1993;14:243-6. doi:10.1016/0167-5699(93)90039-N. (Pubitemid 23186983)
    • (1993) Immunology Today , vol.14 , Issue.6 , pp. 243-246
    • Winter, G.1    Harris, W.J.2
  • 98
    • 33644999128 scopus 로고    scopus 로고
    • CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: A randomized, double-blind, placebo-controlled trial
    • doi:10.1111/j.1365- 2036.2006.02791.x
    • Feagan BG, et al. CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: a randomized, double-blind, placebo-controlled trial. Aliment Pharmacol Ther. 2006;23:617-28. doi:10.1111/j.1365- 2036.2006.02791.x.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 617-628
    • Feagan, B.G.1
  • 99
    • 0034754477 scopus 로고    scopus 로고
    • Etanercept for active Crohn's disease: A randomized, double blind, placebo-controlled trial
    • doi:10.1053/gast.2001.28674
    • Sandborn W, et al. Etanercept for active Crohn's disease: a randomized, double blind, placebo-controlled trial. Gastroenterology. 2001;121:1088-94. doi:10.1053/gast.2001.28674.
    • (2001) Gastroenterology , vol.121 , pp. 1088-1094
    • Sandborn, W.1
  • 100
    • 2542552847 scopus 로고    scopus 로고
    • Etanercept: A clinical review of current and emerging indications
    • DOI 10.1517/14656566.5.5.1175
    • Nanda S, Bathon J. Etanercept: a clinical review of current and emerging indications. Expert Opin Pharmacother. 2004;5:1175-86. doi:10.1517/14656566.5.5. 1175. (Pubitemid 38702345)
    • (2004) Expert Opinion on Pharmacotherapy , vol.5 , Issue.5 , pp. 1175-1186
    • Nanda, S.1    Bathon, J.M.2
  • 101
    • 0344111641 scopus 로고
    • Thalidomide and congenital abnormalities
    • doi:10.1016/S0140-6736(62)91248-5
    • Speirs A. Thalidomide and congenital abnormalities. Lancet. 1962;1:303-5. doi:10.1016/S0140-6736(62)91248-5.
    • (1962) Lancet , vol.1 , pp. 303-305
    • Speirs, A.1
  • 102
    • 0036549801 scopus 로고    scopus 로고
    • Thalidomide as an anticancer agent
    • doi:10.1111/j. 1582-4934.2002.tb00184.x
    • Kumar S, Witzig TE, Rajkumar SV. Thalidomide as an anticancer agent. J Cell Mol Med. 2002;6:160-74. doi:10.1111/j. 1582-4934.2002.tb00184.x.
    • (2002) J Cell Mol Med , vol.6 , pp. 160-174
    • Kumar, S.1    Witzig, T.E.2    Rajkumar, S.V.3
  • 103
    • 0035726260 scopus 로고    scopus 로고
    • Le thalidomide : vers de nouvelles indications ?
    • DOI 10.1016/S1169-8330(01)00208-3, PII S1169833001002083
    • Combe B. Le thalidomide: vers de nouvelles indications ? Rev Rhum. 2001;68:951-7. doi:10.1016/S1169-8330(01)00208-3. (Pubitemid 33626553)
    • (2001) Revue du Rhumatisme (Edition Francaise) , vol.68 , Issue.10-11 , pp. 951-957
    • Combe, B.1
  • 104
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • doi:10.1084/jem.177.6.1675
    • Moreira AL, et al. Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med. 1993;177:1675-80. doi:10.1084/jem.177.6.1675.
    • (1993) J Exp Med , vol.177 , pp. 1675-1680
    • Moreira, A.L.1
  • 105
    • 0029762175 scopus 로고    scopus 로고
    • Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides
    • DOI 10.1021/jm960284r
    • Niwayama S, Turk BE, Liu JO. Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides. J Med Chem. 1996;39:3044-5. doi: 10.1021/jm960284r. (Pubitemid 26260308)
    • (1996) Journal of Medicinal Chemistry , vol.39 , Issue.16 , pp. 3044-3045
    • Niwayama, S.1    Turk, B.E.2    Liu, J.O.3
  • 106
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of Thalidomide analogues that are potent inhibitors of TNF-alpha
    • Corral LG, et al. Differential cytokine modulation and T cell activation by two distinct classes of Thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol. 1999;163:380-6.
    • (1999) J Immunol , vol.163 , pp. 380-386
    • Corral, L.G.1
  • 107
    • 0028216334 scopus 로고
    • Thalidomideis an inhibitor of angiogenesis
    • USA, doi:10.1073/pnas.91.9.4082
    • D'Amato RJ, Loughnan MS, Flynn E, Folkman J. Thalidomideis an inhibitor of angiogenesis. Proc Natl Acad Sci USA. 1994;91:4082-5. doi:10.1073/pnas.91.9. 4082.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 4082-4085
    • D'amato, R.J.1    Loughnan, M.S.2    Flynn, E.3    Folkman, J.4
  • 108
    • 0035933772 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity by thalidomide through suppression of Ikappa B kinase activity
    • doi:10.1074/jbc.M100938200
    • Keifer JA, Guttridge DC, Ashburner BP, Baldwin ASJ. Inhibition of NF-kappa B activity by thalidomide through suppression of Ikappa B kinase activity. J Biol Chem. 2001;276:22382-7.doi:10.1074/jbc.M100938200.
    • (2001) J Biol Chem , vol.276 , pp. 22382-22387
    • Keifer, J.A.1    Guttridge, D.C.2    Ashburner, B.P.3    Baldwin, A.S.J.4
  • 109
    • 27644591608 scopus 로고    scopus 로고
    • Properties of thalidomide and its analogues: Implications for anticancer therapy
    • DOI 10.1208/aapsj070103, 3
    • Teo Steven K. Properties of Thalidomide and its analogues: implications for anticancer therapy. AAPS J. 2005;7:E14-9. doi: 10.1208/aapsj070103. (Pubitemid 41554303)
    • (2005) AAPS Journal , vol.7 , Issue.1
    • Teo, S.K.1
  • 110
    • 0032100486 scopus 로고    scopus 로고
    • Thalidomide costimulates primary human t lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
    • DOI 10.1084/jem.187.11.1885
    • Haslett P, Corral L, Albert M, Kaplan G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8? subset. J Exp Med. 1998;187:1885-92. doi: 10.1084/jem.187.11.1885. (Pubitemid 28262451)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.11 , pp. 1885-1892
    • Haslett, P.A.J.1    Corral, L.G.2    Albert, M.3    Kaplan, G.4
  • 111
    • 42449095004 scopus 로고    scopus 로고
    • A phase i study of Thalidomide Capecitabine and Temozolomide in advanced cancer
    • Laber DA, et al. A phase I study of Thalidomide, Capecitabine and Temozolomide in advanced cancer. Cancer Biol Ther. 2007;6:840-5.
    • (2007) Cancer Biol Ther , vol.6 , pp. 840-845
    • Laber, D.A.1
  • 112
    • 26444468948 scopus 로고    scopus 로고
    • Multiple myeloma: The present and the future
    • Joshua DE. Multiple myeloma: the present and the future. Med J Aust. 2005;183:344.
    • (2005) Med J Aust , vol.183 , pp. 344
    • Joshua, D.E.1
  • 114
    • 52049124279 scopus 로고    scopus 로고
    • Tumour necrosis factor antagonists: Structure, function, and tuberculosis risks
    • doi:10.1016/S1473-3099(08)70227-5
    • Wallis RS. Tumour necrosis factor antagonists: structure, function, and tuberculosis risks. Lancet Infect Dis. 2008;8:601-11. doi:10.1016/S1473-3099(08) 70227-5.
    • (2008) Lancet Infect Dis , vol.8 , pp. 601-611
    • Wallis, R.S.1
  • 115
    • 23844558948 scopus 로고    scopus 로고
    • Tumour necrosis factor inhibitors
    • Nash PT, Florin TH. Tumour necrosis factor inhibitors. Med J Aust. 2005;183:205-8.
    • (2005) Med J Aust , vol.183 , pp. 205-208
    • Nash, P.T.1    Florin, T.H.2
  • 116
    • 38449123106 scopus 로고    scopus 로고
    • Autoimmune hepatitis following Infliximab therapy for ankylosing spondylitis
    • Ozorio G, et al. Autoimmune hepatitis following Infliximab therapy for ankylosing spondylitis. Med J Aust. 2007;187:524-6.
    • (2007) Med J Aust , vol.187 , pp. 524-526
    • Ozorio, G.1
  • 117
    • 54949118761 scopus 로고    scopus 로고
    • Development of Crohn's disease following anti-tumour necrosis factor therapy (etanercept)
    • Yazisiz V, Avci AB, Erbasan F, Yildirim B, Terzioglu E. Development of Crohn's disease following anti-tumour necrosis factor therapy (etanercept). Colorectal Dis. 2008;10:953-4.
    • (2008) Colorectal Dis , vol.10 , pp. 953-954
    • Yazisiz, V.1    Avci, A.B.2    Erbasan, F.3    Yildirim, B.4    Terzioglu, E.5
  • 118
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: Results of the anti-TNF therapy against congestive heart failure (ATTACH) trial
    • DOI 10.1161/01.CIR.0000077913.60364.D2
    • Chung ES, Packer M, Lo KH, Fasanmade AA, Willerson JT. Randomized, double-blind, placebo-controlled, pilot trial of Infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF therapy against congestive heart failure (ATTACH) trial. Circulation. 2003;107:3133-40. doi:10.1161/01.CIR.0000077913.60364.D2. (Pubitemid 36793081)
    • (2003) Circulation , vol.107 , Issue.25 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3    Fasanmade, A.A.4    Willerson, J.T.5
  • 119
    • 0142187584 scopus 로고    scopus 로고
    • Advances in targeted therapy: Safety of biological agents
    • doi:10.1136/ard.62. suppl-2.ii34
    • Keystone EC. Advances in targeted therapy: safety of biological agents. Ann Rheum Dis. 2003;62:ii34-6. doi:10.1136/ard.62. suppl-2.ii34.
    • (2003) Ann Rheum Dis , vol.62
    • Keystone, E.C.1
  • 121
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • DOI 10.1001/jama.295.19.2275
    • Bongartz T, et al. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies : systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA. 2006;295:2275-85. doi: 10.1001/jama.295.19.2275. (Pubitemid 43736578)
    • (2006) Journal of the American Medical Association , vol.295 , Issue.19 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3    Buchan, I.4    Matteson, E.L.5    Montori, V.6
  • 122
    • 33750723407 scopus 로고    scopus 로고
    • Risk of serious infections and malignancies with anti-TNF antibody therapy in rheumatoid arthritis
    • doi:10.1001/jama.296.18.2201-b
    • Okada S, Siegel J. Risk of serious infections and malignancies with anti-TNF antibody therapy in rheumatoid arthritis. JAMA. 2006;296:2201-2. doi:10.1001/jama.296.18.2201-b.
    • (2006) JAMA , vol.296 , pp. 2201-2202
    • Okada, S.1    Siegel, J.2
  • 123
    • 33846592386 scopus 로고    scopus 로고
    • Hepatosplenic T cell lymphoma associated with Infliximab use in young patients treated for inflammatory bowel disease
    • doi:10.1097/MPG.0b013e 31802f6424
    • Mackey AC, Green L, Liang LC, Dinndorf P, Avigan M. Hepatosplenic T cell lymphoma associated with Infliximab use in young patients treated for inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2007;44:265-7. doi:10.1097/MPG.0b013e 31802f6424.
    • (2007) J Pediatr Gastroenterol Nutr , vol.44 , pp. 265-267
    • MacKey, A.C.1    Green, L.2    Liang, L.C.3    Dinndorf, P.4    Avigan, M.5
  • 124
    • 34447534349 scopus 로고    scopus 로고
    • Hepatosplenic T-cell lymphoma in a patient with Crohn's disease who received infliximab therapy [1]
    • DOI 10.1080/10428190701345433, PII 780394996
    • Zeidan A, Sham R, Shapiro J, Baratta A, Kouides P. Hepatosplenic T-cell lymphoma in a patient with Crohn's disease who received infliximab therapy. Leuk Lymphoma. 2007;48: 1410-3. doi:10.1080/10428190701345433. (Pubitemid 47079370)
    • (2007) Leukemia and Lymphoma , vol.48 , Issue.7 , pp. 1410-1413
    • Zeidan, A.1    Sham, R.2    Shapiro, J.3    Baratta, A.4    Kouides, P.5
  • 125
    • 56349126141 scopus 로고    scopus 로고
    • Hepatosplenic Tcell lymphoma following Infliximab therapy for Crohn's disease
    • Drini M, Prichard PJ, Brown GJ, Macrae FA. Hepatosplenic Tcell lymphoma following Infliximab therapy for Crohn's disease. Med J Aust. 2008;189:464-5.
    • (2008) Med J Aust , vol.189 , pp. 464-465
    • Drini, M.1    Prichard, P.J.2    Brown, G.J.3    MacRae, F.A.4
  • 126
    • 17644374819 scopus 로고    scopus 로고
    • Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas
    • DOI 10.1136/ard.2004.030528
    • Geborek P, et al. Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas. Ann Rheum Dis. 2005;64:699-703. doi:10.1136/ard.2004.030528. (Pubitemid 40559295)
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.5 , pp. 699-703
    • Geborek, P.1    Bladstrom, A.2    Turesson, C.3    Gulfe, A.4    Petersson, I.F.5    Saxne, T.6    Olsson, H.7    Jacobsson, L.T.H.8
  • 127
    • 35549007228 scopus 로고    scopus 로고
    • TNF-á inhibitor etanercept and hematologic malignancies: Report of a case and review of the literature
    • DOI 10.1002/ajh.20926
    • Nair B, Raval G, Mehta P. TNF-alpha inhibitor Etanercept and hematologic malignancies: report of a case and review of the literature. Am J Hematol. 2007;82:1022-4. doi:10.1002/ajh.20926. (Pubitemid 350004395)
    • (2007) American Journal of Hematology , vol.82 , Issue.11 , pp. 1022-1024
    • Nair, B.1    Raval, G.2    Mehta, P.3
  • 128
    • 0043072905 scopus 로고    scopus 로고
    • Acute myelogenous leukaemia following Etanercept therapy
    • doi:10.1093/ rheumatology/keg128
    • Bakland G, Nossent H. Acute myelogenous leukaemia following Etanercept therapy. Rheumatology. 2003;42:900-1. doi:10.1093/ rheumatology/keg128.
    • (2003) Rheumatology , vol.42 , pp. 900-901
    • Bakland, G.1    Nossent, H.2
  • 129
    • 0036900501 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist therapy and lymphoma development: Twenty-six cases reported to the Food and Drug Administration
    • DOI 10.1002/art.10679
    • Brown SL, Greene MH, Gershon SK, Edwards ET, Braun MMT. Tumor necrosis factor antagonist therapy and lymphoma development twenty-six cases reported to the Food and Drug Administration. Arthritis Rheum. 2002;46:3151-8. doi:10.1002/art.10679. (Pubitemid 35453523)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.12 , pp. 3151-3158
    • Brown, S.L.1    Greene, M.H.2    Gershon, S.K.3    Edwards, E.T.4    Braun, M.M.5
  • 130
    • 33646477546 scopus 로고    scopus 로고
    • Solid malignancies among patients in the Wegener's Granulomatosis Etanercept trial
    • doi:10.1002/art.21869
    • Stone JH, et al. Solid malignancies among patients in the Wegener's Granulomatosis Etanercept trial. Arthritis Rheum. 2006;54:1608-18. doi:10.1002/art.21869.
    • (2006) Arthritis Rheum , vol.54 , pp. 1608-1618
    • Stone, J.H.1
  • 131
    • 77956914419 scopus 로고    scopus 로고
    • TM (Adalimumab), DN0735V7 CR22-05126. December 20
    • HumiraTM (Adalimumab), DN0735V7 CR22-05126. December 20, 2002:16p.
    • (2002) , pp. 16
  • 132
    • 34247213521 scopus 로고    scopus 로고
    • The comparative safety and effectiveness of TNFalpha antagonists
    • Solomon DH. The comparative safety and effectiveness of TNFalpha antagonists. J Manag Care Pharm. 2007;13:S7-18.
    • (2007) J Manag Care Pharm , vol.13
    • Solomon, D.H.1
  • 133
    • 0033764170 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
    • doi:10.1038/81183
    • Curnis F, et al. Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol. 2000;18:1185-90. doi:10.1038/81183.
    • (2000) Nat Biotechnol , vol.18 , pp. 1185-1190
    • Curnis, F.1
  • 134
    • 0035684074 scopus 로고    scopus 로고
    • Intratumoral administration of low doses of an adenovirus vector encoding tumor necrosis factor alpha together with naive dendritic cells elicits significant suppression of tumor growth without toxicity
    • DOI 10.1089/10430340152677395
    • Kianmanesh A, et al. Intratumoral administration of low doses of an adenovirus vector encoding tumor necrosis factor alpha together with naïve dendritic cells elicits significant suppression of tumor growth without toxicity. Hum Gene Ther. 2001;12: 2035-49. doi:10.1089/10430340152677395. (Pubitemid 34053489)
    • (2001) Human Gene Therapy , vol.12 , Issue.17 , pp. 2035-2049
    • Kianmanesh, A.1    Hackett, N.R.2    Lee, J.M.3    Kikuchi, T.4    Korst, R.J.5    Crystal, R.G.6
  • 135
    • 0031942952 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha in isolated perfusion systems in the treatment of cancer: The Rotterdam Preclinical-Clinical Program
    • doi:10.1002/(SICI)1098-2388(199804/05)14:3<232::AID-SSU7 >3.0.CO;2-9
    • Manusama ER, et al. Tumor necrosis factor-alpha in isolated perfusion systems in the treatment of cancer: the Rotterdam Preclinical-Clinical Program. Semin Surg Oncol. 1998;14:232-7.doi:10.1002/(SICI)1098-2388(199804/05)14: 3<232::AID-SSU7 >3.0.CO;2-9.
    • (1998) Semin Surg Oncol , vol.14 , pp. 232-237
    • Manusama, E.R.1
  • 136
    • 34447532097 scopus 로고    scopus 로고
    • Anti-TNF antibodies for Crohn's disease - In pursuit of the perfect clinical trial
    • DOI 10.1056/NEJMe078111
    • Lewis JD. Anti-TNF antibodies for Crohn's disease- In pursuit of the perfect clinical trial. N Engl J Med. 2007;357:296-8. doi: 10.1056/NEJMe078111. (Pubitemid 47080396)
    • (2007) New England Journal of Medicine , vol.357 , Issue.3 , pp. 296-298
    • Lewis, J.D.1
  • 137
    • 33845685405 scopus 로고    scopus 로고
    • Off-label uses of biologics in dermatology: Rituximab, omalizumab, infliximab, etanercept, adalimumab, efalizumab, and alefacept (Part 2 of 2)
    • DOI 10.1016/j.jaad.2006.07.019, PII S0190962206020858
    • Graves JE, Nunley K, Heffernan MP. Off-label uses of biologics in dermatology: Rituximab, Omalizumab, Infliximab, Etanercept, Adalimumab, Efalizumab, and Alefacept (Part 2 of 2). J Am Acad Dermatol. 2007;56:e55-79. doi:10.1016/j.jaad.2006.07.019. (Pubitemid 44969298)
    • (2007) Journal of the American Academy of Dermatology , vol.56 , Issue.1
    • Graves, J.E.1    Nunley, K.2    Heffernan, M.P.3
  • 138
    • 0142156483 scopus 로고    scopus 로고
    • Comparison of the efficacy of the tumour necrosis factor blocking agents Adalimumab Etanercept and Infliximab when added to methotrexate in patients with active rheumatoid arthritis
    • doi:10.1136/ard.62.suppl-2.ii13
    • Hochberg MC, Tracy JK, Hawkins-Holt M, Flores RH. Comparison of the efficacy of the tumour necrosis factor blocking agents Adalimumab, Etanercept, and Infliximab when added to methotrexate in patients with active rheumatoid arthritis. Ann Rheum Dis. 2003;62(Suppl II):ii13-6. doi:10.1136/ard.62.suppl-2. ii13.
    • (2003) Ann Rheum Dis , vol.62 , Issue.SUPPL. II
    • Hochberg, M.C.1    Tracy, J.K.2    Hawkins-Holt, M.3    Flores, R.H.4
  • 139
    • 34247146861 scopus 로고    scopus 로고
    • Review of eight pharmacoeconomic studies of the value of biologic DMARDs (Adalimumab, Etanercept, and Infliximab) in the management of rheumatoid arthritis
    • Doan QV, Chiou C-F, Dubois RW. Review of eight pharmacoeconomic studies of the value of biologic DMARDs (Adalimumab, Etanercept, and Infliximab) in the management of rheumatoid arthritis. J Manag Care Pharm. 2006;12:555-69.
    • (2006) J Manag Care Pharm , vol.12 , pp. 555-569
    • Doan, Q.V.1    Chiou, C.-F.2    Dubois, R.W.3
  • 140
    • 33845482745 scopus 로고    scopus 로고
    • A systematic review of the effectiveness of Adalimumab, Etanercept and Infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness
    • xi-xiii, 1-229
    • Chen Y-F, et al. A systematic review of the effectiveness of Adalimumab, Etanercept and Infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness. Health Technol Assess 2006;10:iii-iv, xi-xiii, 1-229.
    • (2006) Health Technol Assess , vol.10
    • Chen, Y.-F.1
  • 141
    • 57049092892 scopus 로고    scopus 로고
    • Infliximab-induced hepatitis: Absence of cross-toxicity with Etanercept
    • doi:10.1016/ j.jbspin.2007.12.009
    • Thie'fin G, Morelet A, Heurgue' A, Diebold M-D, Eschard J-P. Infliximab-induced hepatitis: absence of cross-toxicity with Etanercept. Joint Bone Spine. 2008;75:737-9. doi:10.1016/ j.jbspin.2007.12.009.
    • (2008) Joint Bone Spine , vol.75 , pp. 737-739
    • Thiéfin, G.1    Morelet, A.2    Heurgue, A.3    Diebold, M.-D.4    Eschard, J.-P.5
  • 142
    • 38449113617 scopus 로고    scopus 로고
    • Clinical use of anti-TNF-alpha biological agents: A guide for GPs
    • Chang J, Girgis L. Clinical use of anti-TNF-alpha biological agents: A guide for GPs. Aust Fam Physician. 2007;36:1035-8.
    • (2007) Aust Fam Physician , vol.36 , pp. 1035-1038
    • Chang, J.1    Girgis, L.2
  • 143
    • 47749093913 scopus 로고    scopus 로고
    • Recommendations for the diagnosis and treatment of latent and active tuberculosis in inflammatory joint diseases candidates for therapy with tumor necrosis factor alpha inhibitors-March 2008 update
    • Fonseca JE, et al. Recommendations for the diagnosis and treatment of latent and active tuberculosis in inflammatory joint diseases candidates for therapy with tumor necrosis factor alpha inhibitors-March 2008 update. Acta Reumatol Port. 2008;33: 77-85.
    • Acta Reumatol Port , vol.2008 , Issue.33 , pp. 77-85
    • Fonseca, J.E.1
  • 144
    • 36749029427 scopus 로고    scopus 로고
    • Minimizing tuberculosis during antitumour necrosis factor-alpha treatment of inflammatory bowel disease
    • Theis VS, Rhodes JM. Minimizing tuberculosis during antitumour necrosis factor-alpha treatment of inflammatory bowel disease. Aliment Pharmacol Ther. 2008;27:19-30.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 19-30
    • Theis, V.S.1    Rhodes, J.M.2
  • 145
    • 42449157299 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha inhibitors: Screening for tuberculosis infection in inflammatory bowel disease
    • Gupta A, Street AC, Macrae FA. Tumour necrosis factor alpha inhibitors: screening for tuberculosis infection in inflammatory bowel disease. MJA. 2008;188:168-70.
    • (2008) MJA , vol.188 , pp. 168-170
    • Gupta, A.1    Street, A.C.2    MacRae, F.A.3
  • 146
    • 37549063078 scopus 로고    scopus 로고
    • Cytokines and anti-cytokines as therapeutics-an update
    • doi:10.1016/j.ejphar.2007.10.049
    • Tayal V, Kalra B. Cytokines and anti-cytokines as therapeutics-an update. Eur J Pharmacol. 2008;579:1-12. doi:10.1016/j.ejphar.2007.10.049.
    • (2008) Eur J Pharmacol , vol.579 , pp. 1-12
    • Tayal, V.1    Kalra, B.2
  • 147
    • 24144483087 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of Certolizumab pegol (CDP870) for treatment of Crohn's disease
    • doi:10.1053/j.gastro.2005. 06.064
    • Schreiber S, et al. A randomized, placebo-controlled trial of Certolizumab pegol (CDP870) for treatment of Crohn's disease. Gastroenterology. 2005;129:807-18. doi:10.1053/j.gastro.2005. 06.064.
    • (2005) Gastroenterology , vol.129 , pp. 807-818
    • Schreiber, S.1


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