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Volumn 256, Issue , 2004, Pages 53-69

Anti-TNFα therapy of rheumatoid arthritis: What can we learn about chronic disease?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; CYTOKINE; IMMUNOGLOBULIN G; INFLIXIMAB; MONOCLONAL ANTIBODY; TNFR FC FUSION PROTEIN; TNFR-FC FUSION PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 2142756589     PISSN: 15282511     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper
Times cited : (52)

References (52)
  • 1
    • 0029078361 scopus 로고
    • Positive selection in autoimmunity: Abnormal immune responses to a bacterial DNAJ antigenic determinant in patients with early rheumatoid arthritis
    • Albani S, Keystone EC, Nelson JL et al 1995 Positive selection in autoimmunity: abnormal immune responses to a bacterial DNAJ antigenic determinant in patients with early rheumatoid arthritis. Nat Med 1:448-152
    • (1995) Nat Med , vol.1 , pp. 448-152
    • Albani, S.1    Keystone, E.C.2    Nelson, J.L.3
  • 2
    • 0034121690 scopus 로고    scopus 로고
    • Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis
    • Badger AM, Griswold DE, Kapadia R et al 2000 Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis. Arthritis Rheum 43:175-183
    • (2000) Arthritis Rheum , vol.43 , pp. 175-183
    • Badger, A.M.1    Griswold, D.E.2    Kapadia, R.3
  • 4
    • 0024314554 scopus 로고
    • Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan FM, Chantry D, Jackson A, Maini R, Feldmann M 1989b Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 2:244-247
    • (1989) Lancet , vol.2 , pp. 244-247
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.3    Maini, R.4    Feldmann, M.5
  • 5
  • 6
    • 0036164274 scopus 로고    scopus 로고
    • Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: Involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis
    • Brennan FM, Hayes AL, Ciesielski CJ, Green P, Foxwell BMJ, Feldmann M 2002 Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis. Arthritis Rheum 46:31-41
    • (2002) Arthritis Rheum , vol.46 , pp. 31-41
    • Brennan, F.M.1    Hayes, A.L.2    Ciesielski, C.J.3    Green, P.4    Foxwell, B.M.J.5    Feldmann, M.6
  • 7
    • 0029617952 scopus 로고
    • Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti-TNFalpha antibody with the interleukin-1 receptor antagonist
    • Butler DM, Maini RN, Feldmann M, Brennan FM 1995 Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti-TNFalpha antibody with the interleukin-1 receptor antagonist. Eur Cytokine Network 6:225-230
    • (1995) Eur Cytokine Network , vol.6 , pp. 225-230
    • Butler, D.M.1    Maini, R.N.2    Feldmann, M.3    Brennan, F.M.4
  • 8
    • 0033179534 scopus 로고    scopus 로고
    • Charles P, Elliott MJ, DavisDet al 1999 Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J Immunol 163:1521-1528
    • Charles P, Elliott MJ, DavisDet al 1999 Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J Immunol 163:1521-1528
  • 9
    • 0026806992 scopus 로고
    • Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases
    • Cope AP, Aderka D, Doherty M et al 1992 Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. Arthritis Rheum 35:1160-1169
    • (1992) Arthritis Rheum , vol.35 , pp. 1160-1169
    • Cope, A.P.1    Aderka, D.2    Doherty, M.3
  • 10
    • 0027978457 scopus 로고
    • Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis
    • Cope AP, Londei M, Chu NR et al 1994 Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis. J Clin Invest 94:749-760
    • (1994) J Clin Invest , vol.94 , pp. 749-760
    • Cope, A.P.1    Londei, M.2    Chu, N.R.3
  • 11
    • 21544446341 scopus 로고
    • Immunoreactive tumour necrosis factor alpha and biological inhibitor(s) in synovial fluids from rheumatic patients
    • Di Giovine FS, Meager A, Leung H, Duff GW 1988 Immunoreactive tumour necrosis factor alpha and biological inhibitor(s) in synovial fluids from rheumatic patients. Int J Immunopathol Pharmacol 1:17-26
    • (1988) Int J Immunopathol Pharmacol , vol.1 , pp. 17-26
    • Di Giovine, F.S.1    Meager, A.2    Leung, H.3    Duff, G.W.4
  • 12
    • 0027438710 scopus 로고
    • Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
    • Elliott MJ, Maini RN, Feldmann M et al 1993 Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 36:1681-1690
    • (1993) Arthritis Rheum , vol.36 , pp. 1681-1690
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 13
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M et al 1994 Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105-1110
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 14
    • 0035056003 scopus 로고    scopus 로고
    • Anti-TNFα therapy or rheumatoid arthritis: What have we learned?
    • Feldmann M, Maini RN 2001 Anti-TNFα therapy or rheumatoid arthritis: What have we learned? Annu Rev Immunol 19:163-196
    • (2001) Annu Rev Immunol , vol.19 , pp. 163-196
    • Feldmann, M.1    Maini, R.N.2
  • 15
    • 0025099962 scopus 로고
    • Cytokine production in the rheumatoid joint: Implications for treatment
    • Feldmann M, Brennan FM, Chantry D et al 1990 Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis 49:480-486
    • (1990) Ann Rheum Dis , vol.49 , pp. 480-486
    • Feldmann, M.1    Brennan, F.M.2    Chantry, D.3
  • 18
    • 0024822793 scopus 로고
    • Antibodies to cachectin/tumor necrosis factor reduce interleukin 1beta and interleukin 6 appearance during lethal bacteremia
    • Fong Y, Tracey KJ, Moldawer LL et al 1989 Antibodies to cachectin/tumor necrosis factor reduce interleukin 1beta and interleukin 6 appearance during lethal bacteremia. J Exp Med 170:1627-1633
    • (1989) J Exp Med , vol.170 , pp. 1627-1633
    • Fong, Y.1    Tracey, K.J.2    Moldawer, L.L.3
  • 19
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Gregersen PK, Silver J, Winchester RJ 1987 The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 30:1205-1213
    • (1987) Arthritis Rheum , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 20
    • 0025939257 scopus 로고
    • Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor-alpha
    • Haworth C, Brennan FM, Chantry D, Turner M, Maini RN, Feldmann M 1991 Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha. Eur J Immunol 21:2575-2579
    • (1991) Eur J Immunol , vol.21 , pp. 2575-2579
    • Haworth, C.1    Brennan, F.M.2    Chantry, D.3    Turner, M.4    Maini, R.N.5    Feldmann, M.6
  • 21
    • 0022499392 scopus 로고
    • T lymphocytes of rheumatoid arthritis patients show augmented reactivity to a fraction of mycobacteria cross-reactive with cartilage
    • Holoshitz J, Klajman A, Drucker I et al 1986 T lymphocytes of rheumatoid arthritis patients show augmented reactivity to a fraction of mycobacteria cross-reactive with cartilage. Lancet 2:305-309
    • (1986) Lancet , vol.2 , pp. 305-309
    • Holoshitz, J.1    Klajman, A.2    Drucker, I.3
  • 22
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
    • Keane J, Gershon S, Wise RP et al 2001 Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 345:1098-1104
    • (2001) N Engl J Med , vol.345 , pp. 1098-1104
    • Keane, J.1    Gershon, S.2    Wise, R.P.3
  • 23
    • 0030972563 scopus 로고    scopus 로고
    • Microbial DNA in the synovium - a role in aetiology or a mere bystander?
    • Kingsley G 1997 Microbial DNA in the synovium - a role in aetiology or a mere bystander? Lancet 349:1038-1039
    • (1997) Lancet , vol.349 , pp. 1038-1039
    • Kingsley, G.1
  • 24
    • 0027361432 scopus 로고
    • Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
    • Knight DM, Trinh H, Le J et al 1993 Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol 30:1443-1453
    • (1993) Mol Immunol , vol.30 , pp. 1443-1453
    • Knight, D.M.1    Trinh, H.2    Le, J.3
  • 26
    • 0033532386 scopus 로고    scopus 로고
    • The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
    • Li ZW, Chu W, Hu Y et al 1999 The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med 189:1839-1845
    • (1999) J Exp Med , vol.189 , pp. 1839-1845
    • Li, Z.W.1    Chu, W.2    Hu, Y.3
  • 27
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
    • Lipsky PE, van der Heijde DMFM, St Clair EW et al 2000a Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. New Engl J Med 343:1594-1602
    • (2000) New Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    van der Heijde, D.M.F.M.2    St Clair, E.W.3
  • 28
    • 0000609675 scopus 로고    scopus 로고
    • 102 week clinical and radiological results from the ATTRACT trial: A2 year, randomized, controlled, phase 3 trial of infliximab (Remicade) in patients with active rheumatoid arthritis despite methotrexate
    • Lipsky PE, van der Heijde DMFM, St Clair EW et al 2000b 102 week clinical and radiological results from the ATTRACT trial: A2 year, randomized, controlled, phase 3 trial of infliximab (Remicade) in patients with active rheumatoid arthritis despite methotrexate. Arthritis Rheum 47:S242
    • (2000) Arthritis Rheum , vol.47
    • Lipsky, P.E.1    van der Heijde, D.M.F.M.2    St Clair, E.W.3
  • 29
    • 0034048349 scopus 로고    scopus 로고
    • Anti-cytokine therapy for rheumatoid arthritis
    • Maini RN, Taylor PC 2000 Anti-cytokine therapy for rheumatoid arthritis. Annu Rev Med 51:207-229
    • (2000) Annu Rev Med , vol.51 , pp. 207-229
    • Maini, R.N.1    Taylor, P.C.2
  • 30
    • 0031660364 scopus 로고    scopus 로고
    • Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
    • Maini RN, Breedveld FC, Kalden JR et al 1998 Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 41:1552-1563
    • (1998) Arthritis Rheum , vol.41 , pp. 1552-1563
    • Maini, R.N.1    Breedveld, F.C.2    Kalden, J.R.3
  • 31
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial. ATTRACT Study Group
    • Maini R, St Clair EW, Breedveld F et al 1999 Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 354:1932-1939
    • (1999) Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1    St Clair, E.W.2    Breedveld, F.3
  • 32
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland LW, Baumgartner SW, Schiff MH et al 1997 Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 337:141-147
    • (1997) N Engl J Med , vol.337 , pp. 141-147
    • Moreland, L.W.1    Baumgartner, S.W.2    Schiff, M.H.3
  • 33
    • 0033574147 scopus 로고    scopus 로고
    • Etanercept therapy in rheumatoid arthritis. A randomized controlled trial
    • Moreland LW, Schiff MH, Baumgartner SW et al 1999 Etanercept therapy in rheumatoid arthritis. A randomized controlled trial. Ann Intern Med 130:478-486
    • (1999) Ann Intern Med , vol.130 , pp. 478-486
    • Moreland, L.W.1    Schiff, M.H.2    Baumgartner, S.W.3
  • 34
    • 56249118949 scopus 로고    scopus 로고
    • NHS National Institute for Clinical Excellence 2002 Guidance on the use of etanercept and infliximab for the treatment of rheumatoid arthritis. Technical Appraisal Guidance No.36
    • NHS National Institute for Clinical Excellence 2002 Guidance on the use of etanercept and infliximab for the treatment of rheumatoid arthritis. Technical Appraisal Guidance No.36
  • 35
    • 0030013609 scopus 로고    scopus 로고
    • Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor alpha antibody in rheumatoid arthritis
    • Paleolog EM, Hunt M, Elliott MJ, Feldmann M, Maini RN, Woody JN 1996 Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor alpha antibody in rheumatoid arthritis. Arthritis Rheum 39:1082-1091
    • (1996) Arthritis Rheum , vol.39 , pp. 1082-1091
    • Paleolog, E.M.1    Hunt, M.2    Elliott, M.J.3    Feldmann, M.4    Maini, R.N.5    Woody, J.N.6
  • 36
    • 0031810231 scopus 로고    scopus 로고
    • Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis
    • MainiRN
    • Paleolog EM, Young S, Stark AC, McCloskey RV, Feldmann M, MainiRN1998 Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis. Arthritis Rheum 41:1258-1265
    • (1998) Arthritis Rheum , vol.41 , pp. 1258-1265
    • Paleolog, E.M.1    Young, S.2    Stark, A.C.3    McCloskey, R.V.4    Feldmann, M.5
  • 37
    • 0035010959 scopus 로고    scopus 로고
    • Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts
    • Panayi GS, Corrigall VM, Pitzalis C 2001 Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts. Rheum Dis Clin North Am 27:317-334
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 317-334
    • Panayi, G.S.1    Corrigall, V.M.2    Pitzalis, C.3
  • 38
    • 0026677361 scopus 로고
    • Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor
    • Piguet PF, Grau GE, Vesin C, Loetscher H, Gentz R, Lesslauer W 1992 Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology 77:510-514
    • (1992) Immunology , vol.77 , pp. 510-514
    • Piguet, P.F.1    Grau, G.E.2    Vesin, C.3    Loetscher, H.4    Gentz, R.5    Lesslauer, W.6
  • 39
    • 0036839225 scopus 로고    scopus 로고
    • Adalimumab (a fully human anti-tumour necrosis factor alpha monoclonal antibody) in the treatment of active rheumatoid arthritis: The initial results of five trials
    • Rau R 2002 Adalimumab (a fully human anti-tumour necrosis factor alpha monoclonal antibody) in the treatment of active rheumatoid arthritis: the initial results of five trials. Ann Rheum Dis 61:II70-II73
    • (2002) Ann Rheum Dis , vol.61
    • Rau, R.1
  • 40
    • 0022394427 scopus 로고
    • Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever
    • Saklatvala J, Sarsfield SJ, Townsend Y 1985 Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever. J Exp Med 162:1208-1222
    • (1985) J Exp Med , vol.162 , pp. 1208-1222
    • Saklatvala, J.1    Sarsfield, S.J.2    Townsend, Y.3
  • 41
    • 0027375302 scopus 로고
    • Twin concordance rates for rheumatoid arthritis: Results from a nationwide study
    • Silman AJ, MacGregor AJ, Thomson W et al 1993 Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 32:903-907
    • (1993) Br J Rheumatol , vol.32 , pp. 903-907
    • Silman, A.J.1    MacGregor, A.J.2    Thomson, W.3
  • 42
    • 0029877828 scopus 로고    scopus 로고
    • Cigarette smoking increases the risk of rheumatoid arthritis. Results from a nationwide study of disease-discordant twins
    • Silman AJ, Newman J, MacGregor AJ 1996 Cigarette smoking increases the risk of rheumatoid arthritis. Results from a nationwide study of disease-discordant twins. Arthritis Rheum 39:732-735
    • (1996) Arthritis Rheum , vol.39 , pp. 732-735
    • Silman, A.J.1    Newman, J.2    MacGregor, A.J.3
  • 43
    • 0029896957 scopus 로고    scopus 로고
    • Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor a monoclonal antibody treatment in patients with rheumatoid arthritis
    • Tak PP, Taylor PC, Breedveld FC et al 1996 Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor a monoclonal antibody treatment in patients with rheumatoid arthritis. Arthritis Rheum 39:1077-1081
    • (1996) Arthritis Rheum , vol.39 , pp. 1077-1081
    • Tak, P.P.1    Taylor, P.C.2    Breedveld, F.C.3
  • 44
    • 13144256684 scopus 로고    scopus 로고
    • Human parvovirus B19 as a causative agent for rheumatoid arthritis
    • Takahashi Y, Murai C, Shibata S et al 1998 Human parvovirus B19 as a causative agent for rheumatoid arthritis. Proc Natl Acad Sci USA 95:8227-8232
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8227-8232
    • Takahashi, Y.1    Murai, C.2    Shibata, S.3
  • 45
    • 0343674489 scopus 로고    scopus 로고
    • Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis
    • Taylor PC, Peters AM, Paleolog E et al 2000 Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis. Arthritis Rheum 43:38-47
    • (2000) Arthritis Rheum , vol.43 , pp. 38-47
    • Taylor, P.C.1    Peters, A.M.2    Paleolog, E.3
  • 46
    • 0026656850 scopus 로고
    • Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice
    • Thorbecke GJ, Shah R, Leu CH, Kuruvilla AP, Hardison AM, Palladino MA 1992 Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice. Proc Natl Acad Sci USA 89:7375-7379
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7375-7379
    • Thorbecke, G.J.1    Shah, R.2    Leu, C.H.3    Kuruvilla, A.P.4    Hardison, A.M.5    Palladino, M.A.6
  • 48
    • 0033758629 scopus 로고    scopus 로고
    • Systemic anti-tumor necrosis factor alpha therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor alpha synthesis
    • Ulfgren AK, Andersson U, Engstrom M, Klareskog L, Maini RN, Taylor PC 2000 Systemic anti-tumor necrosis factor alpha therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor alpha synthesis. Arthritis Rheum 43:2391-2396
    • (2000) Arthritis Rheum , vol.43 , pp. 2391-2396
    • Ulfgren, A.K.1    Andersson, U.2    Engstrom, M.3    Klareskog, L.4    Maini, R.N.5    Taylor, P.C.6
  • 49
    • 0026644298 scopus 로고
    • Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams RO, Feldmann M, Maini RN 1992 Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 89:9784-9788
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9784-9788
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 50
    • 0028226982 scopus 로고
    • Synergy between anti-CD4 and antitumor necrosis factor in the amelioration of established collagen-induced arthritis
    • Williams RO, Mason LJ, Feldmann M, Maini RN 1994 Synergy between anti-CD4 and antitumor necrosis factor in the amelioration of established collagen-induced arthritis. Proc Natl Acad Sci USA 91:2762-2766
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2762-2766
    • Williams, R.O.1    Mason, L.J.2    Feldmann, M.3    Maini, R.N.4
  • 51
    • 0030611595 scopus 로고    scopus 로고
    • IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
    • Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV 1997 IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 278:866-869
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 52
    • 0024554080 scopus 로고
    • Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions
    • Xu WD, Firestein GS, Taetle R, Kaushansky K, Zvaifler NJ 1989 Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions. J Clin Invest 83:876-882
    • (1989) J Clin Invest , vol.83 , pp. 876-882
    • Xu, W.D.1    Firestein, G.S.2    Taetle, R.3    Kaushansky, K.4    Zvaifler, N.J.5


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