메뉴 건너뛰기




Volumn 51, Issue 8, 2010, Pages 2171-2180

ATP-independent glucose stimulation of sphingosine kinase in rat pancreatic islets

Author keywords

Islets of Langerhans; Sphingosine 1 phosphate; SPHK

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA; GLUCOSE; RNA; SPHINGOSINE KINASE; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 2; PHOSPHOTRANSFERASE; SMALL INTERFERING RNA;

EID: 77956863065     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M000802     Document Type: Article
Times cited : (13)

References (61)
  • 1
    • 14644391944 scopus 로고    scopus 로고
    • Generation and metabolism of bioactive sphingosine-1-phosphate
    • Le Stunff, H., S. Milstein, and S. Spiegel. 2004. Generation and metabolism of bioactive sphingosine-1-phosphate. J. Cell. Biochem. 92: 882-899.
    • (2004) J. Cell. Biochem. , vol.92 , pp. 882-899
    • Le Stunff, H.1    Milstein, S.2    Spiegel, S.3
  • 2
    • 34948813594 scopus 로고    scopus 로고
    • Autocrine and paracrine roles of sphingosine-1-phosphate
    • Alvarez, S. E., S. Milstein, and S. Spiegel. 2007. Autocrine and paracrine roles of sphingosine-1-phosphate. Trends Endocrinol. Metab. 18: 300-307.
    • (2007) Trends Endocrinol. Metab. , vol.18 , pp. 300-307
    • Alvarez, S.E.1    Milstein, S.2    Spiegel, S.3
  • 3
    • 16644383300 scopus 로고    scopus 로고
    • Lysophospholipid receptor-dependent and -independent calcium signaling
    • Meyer Zu Heringdorf, D. 2004. Lysophospholipid receptor-dependent and -independent calcium signaling. J. Cell. Biochem. 92: 937-948.
    • (2004) J. Cell. Biochem. , vol.92 , pp. 937-948
    • Meyer Zu Heringdorf, D.1
  • 4
    • 0037135572 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate, a key cell signaling molecule
    • Spiegel, S., and S. Milstien. 2002. Sphingosine 1-phosphate, a key cell signaling molecule. J. Biol. Chem. 277: 25851-25854.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25851-25854
    • Spiegel, S.1    Milstien, S.2
  • 6
  • 7
    • 0042266314 scopus 로고    scopus 로고
    • Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells
    • Laychock, S. G., Y. Tian, and S. M. Sessanna. 2003. Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells. Diabetes. 52: 1986-1993.
    • (2003) Diabetes , vol.52 , pp. 1986-1993
    • Laychock, S.G.1    Tian, Y.2    Sessanna, S.M.3
  • 8
    • 33748754785 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta cells
    • Laychock, S. G., S. M. Sessanna, M. H. Lin, and L. D. Mastrandrea. 2006. Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta cells. Endocrinology. 147: 4705-4712.
    • (2006) Endocrinology , vol.147 , pp. 4705-4712
    • Laychock, S.G.1    Sessanna, S.M.2    Lin, M.H.3    Mastrandrea, L.D.4
  • 11
    • 17844364503 scopus 로고    scopus 로고
    • Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: Response to cytokines
    • Mastrandrea, L. D., S. M. Sessanna, and S. G. Laychock. 2005. Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: response to cytokines. Diabetes. 54: 1429-1436.
    • (2005) Diabetes , vol.54 , pp. 1429-1436
    • Mastrandrea, L.D.1    Sessanna, S.M.2    Laychock, S.G.3
  • 12
    • 0023525741 scopus 로고
    • Ca2+, cAMP, and phospholipid- derived messengers in coupling mechanisms of insulin secretion
    • Prentki, M., and F. M. Matschinsky. 1987. Ca2+, cAMP, and phospholipid- derived messengers in coupling mechanisms of insulin secretion. Physiol. Rev. 67: 1185-1248.
    • (1987) Physiol. Rev. , vol.67 , pp. 1185-1248
    • Prentki, M.1    Matschinsky, F.M.2
  • 13
    • 22844446279 scopus 로고    scopus 로고
    • ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter
    • Lawrence, M. C., K. McGlynn, B. H. Park, and M. H. Cobb. 2005. ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter. J. Biol. Chem. 280: 26751-26759.
    • (2005) J. Biol. Chem. , vol.280 , pp. 26751-26759
    • Lawrence, M.C.1    McGlynn, K.2    Park, B.H.3    Cobb, M.H.4
  • 14
    • 3242656480 scopus 로고    scopus 로고
    • Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: A role for protein kinase B in the Akt?
    • Dickson, L. M., and C. J. Rhodes. 2004. Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am. J. Physiol. Endocrinol. Metab. 287: E192-E198.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287
    • Dickson, L.M.1    Rhodes, C.J.2
  • 15
    • 9444278526 scopus 로고    scopus 로고
    • Metabolic regulation of pancreatic beta-cell ATP-sensitive K+ channel: A pas de deux
    • Tarasov, A., J. Dusonchet, and F. Ashcroft. 2004. Metabolic regulation of pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux. Diabetes. 53: S113-S122.
    • (2004) Diabetes , vol.53
    • Tarasov, A.1    Dusonchet, J.2    Ashcroft, F.3
  • 16
    • 0026451942 scopus 로고
    • Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function
    • Eizirik, D. L., G. S. Korbutt, and C. Hellerstrom. 1992. Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function. J. Clin. Invest. 90: 1263-1268.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1263-1268
    • Eizirik, D.L.1    Korbutt, G.S.2    Hellerstrom, C.3
  • 17
    • 0022522943 scopus 로고
    • Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions
    • Leahy, J. L., H. E. Cooper, D. A. Deal, and G. C. Weir. 1986. Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions. J. Clin. Invest. 77: 908-915.
    • (1986) J. Clin. Invest. , vol.77 , pp. 908-915
    • Leahy, J.L.1    Cooper, H.E.2    Deal, D.A.3    Weir, G.C.4
  • 18
    • 0026757632 scopus 로고
    • Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations
    • Robertson, R. P., H. J. Zhang, K. L. Pyzdrowski, and T. F. Walseth. 1992. Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations. J. Clin. Invest. 90: 320-325.
    • (1992) J. Clin. Invest. , vol.90 , pp. 320-325
    • Robertson, R.P.1    Zhang, H.J.2    Pyzdrowski, K.L.3    Walseth, T.F.4
  • 19
    • 0029099330 scopus 로고
    • Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets
    • Laychock, S. G. 1995. Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets. Mol. Cell. Endocrinol. 113: 19-28.
    • (1995) Mol. Cell. Endocrinol. , vol.113 , pp. 19-28
    • Laychock, S.G.1
  • 20
    • 0034982387 scopus 로고    scopus 로고
    • High glucose causes apoptosis in cultured human pancreatic islets of langerhans: A potential role for regulation of specific Bcl family genes towards an apoptotic cell death program
    • Federici, M., M. Hribal, L. Perego, M. Ranalli, Z. Caradonna, C. Perego, L. Usellini, R. Nano, P. Bonini, F. Bertuzzi, et al. 2001. High glucose causes apoptosis in cultured human pancreatic islets of langerhans: a potential role for regulation of specific Bcl family genes towards an apoptotic cell death program. Diabetes. 50: 1290-1301.
    • (2001) Diabetes , vol.50 , pp. 1290-1301
    • Federici, M.1    Hribal, M.2    Perego, L.3    Ranalli, M.4    Caradonna, Z.5    Perego, C.6    Usellini, L.7    Nano, R.8    Bonini, P.9    Bertuzzi, F.10
  • 22
    • 0040799181 scopus 로고    scopus 로고
    • Glucose stimulates islet β-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms
    • Sjoholm, A. 1997. Glucose stimulates islet β-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms. Diabetes. 46: 1141-1147.
    • (1997) Diabetes , vol.46 , pp. 1141-1147
    • Sjoholm, A.1
  • 23
    • 0027321407 scopus 로고
    • Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets
    • Xia, M., and S. G. Laychock. 1993. Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets. Diabetes. 42: 1392-1400.
    • (1993) Diabetes , vol.42 , pp. 1392-1400
    • Xia, M.1    Laychock, S.G.2
  • 24
    • 0026550830 scopus 로고
    • Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
    • Asfari, M., D. Janjic, P. Meda, G. Li, P. A. Halban, and C. B. Wollheim. 1992. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology. 130: 167-178.
    • (1992) Endocrinology , vol.130 , pp. 167-178
    • Asfari, M.1    Janjic, D.2    Meda, P.3    Li, G.4    Halban, P.A.5    Wollheim, C.B.6
  • 25
    • 0028834086 scopus 로고
    • Oligonucleotides with fluoresent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization
    • Livak, K. J., S. J. Flood, J. Marmaro, W. Giusti, and K. Deetz. 1995. Oligonucleotides with fluoresent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl. 4: 357-362.
    • (1995) PCR Methods Appl. , vol.4 , pp. 357-362
    • Livak, K.J.1    Flood, S.J.2    Marmaro, J.3    Giusti, W.4    Deetz, K.5
  • 26
    • 4344608398 scopus 로고    scopus 로고
    • An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans
    • Bain, J. R., J. C. Schisler, K. Takeuchi, C. B. Newgard, and T. C. Becker. 2004. An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans. Diabetes. 53: 2190-2194.
    • (2004) Diabetes , vol.53 , pp. 2190-2194
    • Bain, J.R.1    Schisler, J.C.2    Takeuchi, K.3    Newgard, C.B.4    Becker, T.C.5
  • 27
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411: 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 28
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T. R., R. Bernards, and R. Agami. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296: 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 29
    • 0023093265 scopus 로고
    • Effects of cyclic guanosine 3′,5′-monophosphate on glucose utilization in isolated islets of Langerhans
    • Laychock, S. G. 1987. Effects of cyclic guanosine 3′,5′- monophosphate on glucose utilization in isolated islets of Langerhans. Endocrinology. 120: 517-524.
    • (1987) Endocrinology , vol.120 , pp. 517-524
    • Laychock, S.G.1
  • 30
    • 0018133133 scopus 로고
    • On the biochemical nature of triose- and hexose-stimulated insulin secretion
    • Zawalich, W. S., E. S. Dye, R. Rognstad, and F. M. Matschinsky. 1978. On the biochemical nature of triose- and hexose-stimulated insulin secretion. Endocrinology. 103: 2027-2034.
    • (1978) Endocrinology , vol.103 , pp. 2027-2034
    • Zawalich, W.S.1    Dye, E.S.2    Rognstad, R.3    Matschinsky, F.M.4
  • 31
    • 0000904661 scopus 로고
    • Localization of the primary metabolic block produced by 2-deoxyglucose
    • Wick, A. N., D. R. Drury, H. I. Nakada, and J. B. Wolfe. 1957. Localization of the primary metabolic block produced by 2-deoxyglucose. J. Biol. Chem. 224: 963-969.
    • (1957) J. Biol. Chem. , vol.224 , pp. 963-969
    • Wick, A.N.1    Drury, D.R.2    Nakada, H.I.3    Wolfe, J.B.4
  • 32
    • 0026522717 scopus 로고
    • Relationships between energy level and insulin secretion in isolated rat islets of Langerhans. Manipulation of [ATP]/[ADP][Pi] by 2-deoxy-D-glucose
    • Ohta, M., D. Nelson, J. M. Wilson, M. D. Meglasson, and M. Erecinska. 1992. Relationships between energy level and insulin secretion in isolated rat islets of Langerhans. Manipulation of [ATP]/[ADP][Pi] by 2-deoxy-D-glucose. Biochem. Pharmacol. 43: 1859-1864.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 1859-1864
    • Ohta, M.1    Nelson, D.2    Wilson, J.M.3    Meglasson, M.D.4    Erecinska, M.5
  • 33
    • 0037023692 scopus 로고    scopus 로고
    • Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: A survey of four fuel secretagogues
    • Antinozzi, P. A., H. Ishihara, C. B. Newgard, and C. B. Wollheim. 2002. Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues. J. Biol. Chem. 277: 11746-11755.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11746-11755
    • Antinozzi, P.A.1    Ishihara, H.2    Newgard, C.B.3    Wollheim, C.B.4
  • 34
    • 27644524630 scopus 로고    scopus 로고
    • Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells
    • Wang, L., X. P. Xing, A. Holmes, C. Wadham, J. R. Gamble, M. A. Vadas, and P. Xia. 2005. Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells. Circ. Res. 97: 891-899.
    • (2005) Circ. Res. , vol.97 , pp. 891-899
    • Wang, L.1    Xing, X.P.2    Holmes, A.3    Wadham, C.4    Gamble, J.R.5    Vadas, M.A.6    Xia, P.7
  • 35
    • 9444234587 scopus 로고    scopus 로고
    • Signaling elements involved in the metabolic regulation of mTOR by nutrients, incretins, and growth factors in islets
    • Kwon, G., C. A. Marshall, K. L. Pappan, M. S. Remedi, and M. L. McDaniel. 2004. Signaling elements involved in the metabolic regulation of mTOR by nutrients, incretins, and growth factors in islets. Diabetes. 53: S225-S232.
    • (2004) Diabetes , vol.53
    • Kwon, G.1    Marshall, C.A.2    Pappan, K.L.3    Remedi, M.S.4    McDaniel, M.L.5
  • 36
    • 0034705104 scopus 로고    scopus 로고
    • Expression profiling of pancreatic beta cells: Glucose regulation of secretory and metabolic pathway genes
    • Webb, G. C., M. S. Akbar, C. Zhao, and D. F. Steiner. 2000. Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes. Proc. Natl. Acad. Sci. USA. 97: 5773-5778.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5773-5778
    • Webb, G.C.1    Akbar, M.S.2    Zhao, C.3    Steiner, D.F.4
  • 37
    • 33645638812 scopus 로고    scopus 로고
    • Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: Effects on cell cycle progression in rodent islets
    • Kwon, G., C. A. Marshall, H. Liu, K. L. Pappan, M. S. Remedi, and M. L. McDaniel. 2006. Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets. J. Biol. Chem. 281: 3261-3267.
    • (2006) J. Biol. Chem. , vol.281 , pp. 3261-3267
    • Kwon, G.1    Marshall, C.A.2    Liu, H.3    Pappan, K.L.4    Remedi, M.S.5    McDaniel, M.L.6
  • 39
    • 0030780015 scopus 로고    scopus 로고
    • Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
    • Edsall, L. C., G. G. Pirianov, and S. Spiegel. 1997. Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. J. Neurosci. 17: 6952-6960.
    • (1997) J. Neurosci. , vol.17 , pp. 6952-6960
    • Edsall, L.C.1    Pirianov, G.G.2    Spiegel, S.3
  • 40
    • 0030592536 scopus 로고    scopus 로고
    • Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity
    • Buehrer, B. M., E. S. Bardes, and R. M. Bell. 1996. Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity. Biochim. Biophys. Acta. 1303: 233-242.
    • (1996) Biochim. Biophys. Acta , vol.1303 , pp. 233-242
    • Buehrer, B.M.1    Bardes, E.S.2    Bell, R.M.3
  • 41
    • 0031819196 scopus 로고    scopus 로고
    • Sphingosine kinase mediates cyclic AMP suppression of apoptosis in rat periosteal cells
    • Machwate, M., S. B. Rodan, G. A. Rodan, and S. I. Harada. 1998. Sphingosine kinase mediates cyclic AMP suppression of apoptosis in rat periosteal cells. Mol. Pharmacol. 54: 70-77.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 70-77
    • Machwate, M.1    Rodan, S.B.2    Rodan, G.A.3    Harada, S.I.4
  • 43
    • 0028300922 scopus 로고
    • Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): Demonstration of cell type-specific response -a preliminary note
    • Mazurek, N., T. Megidish, S. Hakomori, and Y. Igarashi. 1994. Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response -a preliminary note. Biochem. Biophys. Res. Commun. 198: 1-9.
    • (1994) Biochem. Biophys. Res. Commun. , vol.198 , pp. 1-9
    • Mazurek, N.1    Megidish, T.2    Hakomori, S.3    Igarashi, Y.4
  • 44
    • 0029050932 scopus 로고
    • Identification and subcellular localization of sphinganine-phosphatases in rat liver
    • De Ceuster, P., G. P. Mannaerts, and P. P. VanVeldhoven. 1995. Identification and subcellular localization of sphinganine-phosphatases in rat liver. Biochem J. 311(Pt 1): 139-146.
    • (1995) Biochem J. , vol.311 , Issue.PART 1 , pp. 139-146
    • De Ceuster, P.1    Mannaerts, G.P.2    VanVeldhoven, P.P.3
  • 47
    • 0009555101 scopus 로고
    • Effects of L-leucine and alpha-ketoisocaproic acid upon insulin secretion and metabolism of isolated pancreatic islets
    • Panten, U., E. von Kriegstein, W. Poser, J. Schonborn, and A. Hasselblatt. 1972. Effects of L-leucine and alpha-ketoisocaproic acid upon insulin secretion and metabolism of isolated pancreatic islets. FEBS Lett. 20: 225-228.
    • (1972) FEBS Lett. , vol.20 , pp. 225-228
    • Panten, U.1    Von Kriegstein, E.2    Poser, W.3    Schonborn, J.4    Hasselblatt, A.5
  • 48
    • 0033959401 scopus 로고    scopus 로고
    • Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion
    • McClenaghan, N. H., and P. R. Flatt. 2000. Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion. Pancreas. 20: 38-46.
    • (2000) Pancreas , vol.20 , pp. 38-46
    • McClenaghan, N.H.1    Flatt, P.R.2
  • 51
    • 0034010473 scopus 로고    scopus 로고
    • Difference in mechanism between glyceraldehyde- and glucose- induced insulin secretion from isolated rat pancreatic islets
    • Taniguchi, S., M. Okinaka, K. Tanigawa, and I. Miwa. 2000. Difference in mechanism between glyceraldehyde- and glucose- induced insulin secretion from isolated rat pancreatic islets. J. Biochem. 127: 289-295.
    • (2000) J. Biochem. , vol.127 , pp. 289-295
    • Taniguchi, S.1    Okinaka, M.2    Tanigawa, K.3    Miwa, I.4
  • 52
    • 0018126887 scopus 로고
    • Localization of inorganic phosphate in the pancreatic B cells and its loss on glucose stimulation
    • Freinkel, N., K. C. Pedley, P. Wooding, and R. M. Dawson. 1978. Localization of inorganic phosphate in the pancreatic B cells and its loss on glucose stimulation. Science. 201: 1124-1126.
    • (1978) Science , vol.201 , pp. 1124-1126
    • Freinkel, N.1    Pedley, K.C.2    Wooding, P.3    Dawson, R.M.4
  • 53
    • 15344340524 scopus 로고
    • Metabolism of ascites tumor cells. III. Effect of 2-deoxyglucose phosphorylation on phosphorus metabolism
    • McComb, R. B., and W. D. Yushok. 1964. Metabolism of ascites tumor cells. III. Effect of 2-deoxyglucose phosphorylation on phosphorus metabolism. Cancer Res. 24: 193-197.
    • (1964) Cancer Res. , vol.24 , pp. 193-197
    • McComb, R.B.1    Yushok, W.D.2
  • 54
    • 0026688668 scopus 로고
    • Glutamate production in islets of Langerhans: Properties of phosphate-activated glutaminase
    • Michalik, M., J. Nelson, and M. Erecinska. 1992. Glutamate production in islets of Langerhans: properties of phosphate-activated glutaminase. Metabolism. 41: 1319-1326.
    • (1992) Metabolism , vol.41 , pp. 1319-1326
    • Michalik, M.1    Nelson, J.2    Erecinska, M.3
  • 55
    • 0019170667 scopus 로고
    • Stimulation of insulin release by L-glutamine
    • Sener, A., and W. J. Malaisse. 1980. Stimulation of insulin release by L-glutamine. Mol. Cell. Biochem. 33: 157-159.
    • (1980) Mol. Cell. Biochem. , vol.33 , pp. 157-159
    • Sener, A.1    Malaisse, W.J.2
  • 56
    • 0035839128 scopus 로고    scopus 로고
    • Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor
    • Kleuser, B., M. Maceyka, S. Milstien, and S. Spiegel. 2001. Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor. FEBS Lett. 503: 85-90.
    • (2001) FEBS Lett. , vol.503 , pp. 85-90
    • Kleuser, B.1    Maceyka, M.2    Milstien, S.3    Spiegel, S.4
  • 57
    • 0031040704 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid
    • Yatomi, Y., S. Yamamura, F. Ruan, and Y. Igarashi. 1997. Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. J. Biol. Chem. 272: 5291-5297.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5291-5297
    • Yatomi, Y.1    Yamamura, S.2    Ruan, F.3    Igarashi, Y.4
  • 58
    • 0036738085 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate as a therapeutic agent
    • Spiegel, S., and R. Kolesnick. 2002. Sphingosine 1-phosphate as a therapeutic agent. Leukemia. 16: 1596-1602.
    • (2002) Leukemia , vol.16 , pp. 1596-1602
    • Spiegel, S.1    Kolesnick, R.2
  • 59
    • 0029810808 scopus 로고    scopus 로고
    • Structural requirements of sphingosylphosphocholine and sphingosine- 1-phosphate for stimulation of activator protein-1 activity
    • Berger, A., R. Bittman, R. R. Schmidt, and S. Spiegel. 1996. Structural requirements of sphingosylphosphocholine and sphingosine- 1-phosphate for stimulation of activator protein-1 activity. Mol. Pharmacol. 50: 451-457.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 451-457
    • Berger, A.1    Bittman, R.2    Schmidt, R.R.3    Spiegel, S.4
  • 60
    • 0029862561 scopus 로고    scopus 로고
    • Sphingolipid metabolism and cell growth regulation
    • Spiegel, S., and A. H. Merrill, Jr. 1996. Sphingolipid metabolism and cell growth regulation. FASEB J. 10: 1388-1397.
    • (1996) FASEB J. , vol.10 , pp. 1388-1397
    • Spiegel, S.1    Merrill Jr., A.H.2
  • 61
    • 0029775306 scopus 로고    scopus 로고
    • Involvement of sphingolipids metabolites in cellular proliferation modulated by ganglioside GM1
    • Wang, F., N. E. Buckley, A. Olivera, K. A. Goodemote, Y. Su, and S. Spiegel. 1996. Involvement of sphingolipids metabolites in cellular proliferation modulated by ganglioside GM1. Glycoconj. J. 13: 937-945.
    • (1996) Glycoconj. J. , vol.13 , pp. 937-945
    • Wang, F.1    Buckley, N.E.2    Olivera, A.3    Goodemote, K.A.4    Su, Y.5    Spiegel, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.