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Volumn 51, Issue 8, 2010, Pages 2422-2427

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: Lessons from the METSIM study

Author keywords

Cholestanol; Insulin resistance; Lathosterol; Metabolic syndrome in men; Sitosterol; Type 2 diabetes

Indexed keywords

CHOLESTEROL; GLUCOSE; INSULIN; LATHOSTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; SITOSTEROL; SULFONYLUREA; BIOLOGICAL MARKER; CHOLESTANOL; PHYTOSTEROL; SQUALENE;

EID: 77956849936     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.P006619     Document Type: Article
Times cited : (60)

References (23)
  • 1
    • 38549141572 scopus 로고    scopus 로고
    • Cellular cholesterol trafficking and compartmentalization
    • Ikonen, E. 2008. Cellular cholesterol trafficking and compartmentalization. Nat. Rev. Mol. Cell Biol. 9: 125-138.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 125-138
    • Ikonen, E.1
  • 3
    • 0036726421 scopus 로고    scopus 로고
    • Diabetes contributes to cholesterol metabolism regardless of obesity
    • Simonen, P. P., H. K. Gylling, and T. A. Miettinen. 2002. Diabetes contributes to cholesterol metabolism regardless of obesity. Diabetes Care. 25: 1511-1515.
    • (2002) Diabetes Care , vol.25 , pp. 1511-1515
    • Simonen, P.P.1    Gylling, H.K.2    Miettinen, T.A.3
  • 4
    • 40949164211 scopus 로고    scopus 로고
    • The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes
    • Simonen, P., H. Gylling, and T. A. Miettinen. 2008. The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes. Atherosclerosis. 197: 883-888.
    • (2008) Atherosclerosis , vol.197 , pp. 883-888
    • Simonen, P.1    Gylling, H.2    Miettinen, T.A.3
  • 6
    • 0023005737 scopus 로고
    • Cholesterol and bile acid metabolism in middle-aged diabetics
    • Andersen, E., P. Hellström, and K. Hellström. 1986. Cholesterol and bile acid metabolism in middle-aged diabetics. Diabetes Metab. 12: 261-267. (Pubitemid 17201536)
    • (1986) Diabete et Metabolisme , vol.12 , Issue.5 , pp. 261-267
    • Andersen, E.1    Hellstrom, P.2    Hellstrom, K.3
  • 7
    • 0029884567 scopus 로고    scopus 로고
    • Associations of fasting blood glucose with cholesterol absorption and synthesis in nondiabetic middle-aged men
    • Stranberg, T. E., V. Salomaa, H. Vanhanen, and T. A. Miettinen. 1996. Associations of fasting blood glucose with cholesterol absorption and synthesis in nondiabetic middle-aged men. Diabetes. 45: 755-761.
    • (1996) Diabetes , vol.45 , pp. 755-761
    • Stranberg, T.E.1    Salomaa, V.2    Vanhanen, H.3    Miettinen, T.A.4
  • 8
    • 1542723726 scopus 로고    scopus 로고
    • Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men
    • DOI 10.1194/jlr.M300368-JLR200
    • Pihlajamäki, J., H. Gylling, T. A. Miettinen, and M. Laakso. 2004. Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. J. Lipid Res. 45: 507-517. (Pubitemid 38337997)
    • (2004) Journal of Lipid Research , vol.45 , Issue.3 , pp. 507-512
    • Pihlajamaki, J.1    Gylling, H.2    Miettinen, T.A.3    Laakso, M.4
  • 9
    • 0033790554 scopus 로고    scopus 로고
    • Cholesterol absorption effi- Ciency and sterol metabolism in obesity
    • Miettinen, T. A., and H. Gylling. 2000. Cholesterol absorption effi- ciency and sterol metabolism in obesity. Atherosclerosis. 153: 241-248.
    • (2000) Atherosclerosis , vol.153 , pp. 241-248
    • Miettinen, T.A.1    Gylling, H.2
  • 10
    • 0025156823 scopus 로고
    • Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population
    • Miettinen, T. A., R. S. Tilvis, and Y. A. Kesäniemi. 1990. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am. J. Epidemiol. 131: 20-31.
    • (1990) Am. J. Epidemiol. , vol.131 , pp. 20-31
    • Miettinen, T.A.1    Tilvis, R.S.2    Kesäniemi, Y.A.3
  • 11
    • 65549163338 scopus 로고    scopus 로고
    • Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men
    • Stančáková, A., M. Javorský, T. Kuulasmaa, S. M. Haffner, J. Kuusisto, and M. Laakso. 2009. Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men. Diabetes. 58: 1212-1221.
    • (2009) Diabetes , vol.58 , pp. 1212-1221
    • Stančáková, A.1    Javorský, M.2    Kuulasmaa, T.3    Haffner, S.M.4    Kuusisto, J.5    Laakso, M.6
  • 12
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • Matsuda, M., and R. A. DeFronzo. 1999. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 22: 1462-1470.
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.A.2
  • 13
    • 0023865658 scopus 로고
    • Cholesterol metabolism during ketoconazole treatment in man
    • Miettinen, T. A. 1988. Cholesterol metabolism during ketoconazole treatment in man. J. Lipid Res. 29: 43-51.
    • (1988) J. Lipid Res. , vol.29 , pp. 43-51
    • Miettinen, T.A.1
  • 15
    • 0142186766 scopus 로고    scopus 로고
    • Plasma markers of cholesterol homeostasis and apolipoprotein B-100 kinetics in the metabolic syndrome
    • Chan, D. C., G. F. Watts, P. H. Barrett, F. H. O'Neill, and G. R. Thompson. 2003. Plasma markers of cholesterol homeostasis and apolipoprotein B-100 kinetics in the metabolic syndrome. Obes. Res. 11: 591-596.
    • (2003) Obes. Res. , vol.11 , pp. 591-596
    • Chan, D.C.1    Watts, G.F.2    Barrett, P.H.3    O'Neill, F.H.4    Thompson, G.R.5
  • 16
    • 0033919190 scopus 로고    scopus 로고
    • Introducing a new component of the metabolic syndrome: Low cholesterol absorption
    • Simonen, P., H. Gylling, A. N. Howard, and T. A. Miettinen. 2000. Introducing a new component of the metabolic syndrome: low cholesterol absorption. Am. J. Clin. Nutr. 72: 82-88.
    • (2000) Am. J. Clin. Nutr. , vol.72 , pp. 82-88
    • Simonen, P.1    Gylling, H.2    Howard, A.N.3    Miettinen, T.A.4
  • 17
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J. D., J. L. Goldstein, and M. S. Brown. 2002. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109: 1125-1131.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 18
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning, J. D., and J. D. Horton. 2004. Molecular mediators of hepatic steatosis and liver injury. J. Clin. Invest. 114: 147-152.
    • (2004) J. Clin. Invest. , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 19
    • 0942279560 scopus 로고    scopus 로고
    • Downregulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes
    • Bloks, V. W., W. M. Bakker-Van Waarde, H. J. Verkade, I. P. Kema, H. Wolters, E. Vink, A. K. Groen, and F. Kuipers. 2004. Downregulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes. Diabetologia. 47: 104-112.
    • (2004) Diabetologia , vol.47 , pp. 104-112
    • Bloks, V.W.1    Bakker-Van Waarde, W.M.2    Verkade, H.J.3    Kema, I.P.4    Wolters, H.5    Vink, E.6    Groen, A.K.7    Kuipers, F.8
  • 20
    • 33845449949 scopus 로고    scopus 로고
    • Cholesterol absorption and synthesis in children with type 1 diabetes
    • Järvisalo, M., O. Raitakari, H. Gylling, and T. A. Miettinen. 2006. Cholesterol absorption and synthesis in children with type 1 diabetes. Diabetes Care. 29: 2300-2304.
    • (2006) Diabetes Care , vol.29 , pp. 2300-2304
    • Järvisalo, M.1    Raitakari, O.2    Gylling, H.3    Miettinen, T.A.4
  • 21
    • 1042280193 scopus 로고    scopus 로고
    • Low synthesis and high absorption of cholesterol characterize type 1 diabetes
    • Miettinen, T. A., H. Gylling, J. Tuominen, P. Simonen, and V. Koivisto. 2004. Low synthesis and high absorption of cholesterol characterize type 1 diabetes. Diabetes Care. 27: 53-58.
    • (2004) Diabetes Care , vol.27 , pp. 53-58
    • Miettinen, T.A.1    Gylling, H.2    Tuominen, J.3    Simonen, P.4    Koivisto, V.5
  • 22
    • 0242660388 scopus 로고    scopus 로고
    • Sitosterolemia: A gateway to new knowledge about cholesterol metabolism
    • Berge, K. E. 2003. Sitosterolemia: a gateway to new knowledge about cholesterol metabolism. Ann. Med. 35: 502-511.
    • (2003) Ann. Med. , vol.35 , pp. 502-511
    • Berge, K.E.1
  • 23
    • 32444441330 scopus 로고    scopus 로고
    • Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
    • Cohen, J. C., A. Pertsemlidis, S. Fahmi, S. Esmail, G. L. Vega, S. M. Grundy, and H. H. Hobbs. 2006. Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc. Natl. Acad. Sci. USA. 103: 1810-1815.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1810-1815
    • Cohen, J.C.1    Pertsemlidis, A.2    Fahmi, S.3    Esmail, S.4    Vega, G.L.5    Grundy, S.M.6    Hobbs, H.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.