Potent and fully noncompetitive peptidomimetic inhibitor of multidrug resistance P-glycoprotein

Journal of Medicinal Chemistry

Volumn 53, Issue 18, 2010, Pages 6720-6729

  Arnaud, Ophélie ^a   Koubeissi, Ali ^a   Ettouati, Laurent ^a   Terreux, Raphaël ^a   Alamé, Ghina ^a   Grenot, Catherine ^a   Dumontet, Charles ^a   Di Pietro, Attilio ^a   Paris, Joëlle ^a   Falson, Pierre ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMINOMETHYLENE DERIVATIVE; DAUNORUBICIN; GLYCOPROTEIN P; HOE 33342; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN; PEPTIDOMIMETIC AGENT; REVERSIN 121; UNCLASSIFIED DRUG; LIGAND; OLIGOPEPTIDE;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CORRELATION COEFFICIENT; CYTOTOXICITY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IC 50; NONHUMAN; STRUCTURE ACTIVITY RELATION; 3T3 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; GENETIC TRANSFECTION; GENETICS; HAMSTER; MOUSE; MULTIDRUG RESISTANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CRICETINAE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; LIGANDS; MICE; MODELS, MOLECULAR; NIH 3T3 CELLS; OLIGOPEPTIDES; P-GLYCOPROTEIN; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 77956722593     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100839w     Document Type: Article

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