Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells

Cell Death and Differentiation

Volumn 17, Issue 10, 2010, Pages 1624-1635

  Kutuk, O ^a   Letai, A ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

apoptosis; BH3; Bim; Bmf; paclitaxel; Puma

Indexed keywords

BIM PROTEIN; CYTOCHROME C; PACLITAXEL; PROTEIN BAK; PROTEIN BAX; PUMA PROTEIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BREAST NEOPLASMS; CELL LINE, TUMOR; DIMERIZATION; FEMALE; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; PACLITAXEL; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 77956710766     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.41     Document Type: Article

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