Electrochemical Immunosensors on the Route to Proteomic Chips

Perspectives in Bioanalysis

Volumn 1, Issue C, 2005, Pages 451-483

  Warsinke, Axel ^a   Stöcklein, Walter ^a   Leupold, Eik ^a   Micheel, Edith ^a   Scheller, Frieder W ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956687282     PISSN: 18710069     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1871-0069(05)01014-1     Document Type: Article

References (144)

1. Abdel-Hamid I., Ghindilis A.L., Atanasov P., and Wilkins E. Flow-through immunoassay system for determination of staphylococcal protein a. Anal. Lett. 32 (1999) 1081
2. Aizawa M., Morioka A., and Suzuki S. An enzyme immunosensor for the electrochemical determination of the tumor antigen alpha-fetoprotein. Anal. Chim. Acta 115 (1980) 61
3. Athey D., and McNeil C.J. Amplified electrochemical immunoassay for thyrotropin using thermophilic β-NADH oxidase. J. Immunol. Meth. 176 (1994) 153
4. Athey D., McNeil C.J., Bailey W.R., Hager H.J., Mullen W.H., and Russell L.J. Homogeneous amperometric immunoassay for theophylline in whole blood. Biosens. Bioelectron. 8 (1993) 415
5. Bates D.L. Enzyme amplification in diagnostics. Trends Biotechnol. 5 (1987) 204
6. Bauer C.G., Eremenko A.V., Ehrentreich-Förster E., Bier F.F., Makower A., Halsall H.B., Heineman W.R., and Scheller F.W. Zeptomole-detecting biosensor for alkaline phosphatase in an electrochemical immunoassay for 2,4-dichlorophenoxyacetic acid. Anal. Chem. 68 (1996) 2453
7. Bauer C.G., Eremenko A.V., Kühn A., Kürzinger K., Makower A., and Scheller F.W. Automated amplified flow immunoassay for cocaine. Anal. Chem. 70 (1998) 4624
8. Bellecave P., Andreola M.L., Ventura M., Tarrago-Litvak L., Litvak S., and Astier-Gin T. Selection of DNA aptamers that bind the RNA-dependent RNA polymerase of Hepatitis C virus and inhibit viral RNA synthesis in vitro. Oligonucleotides 13 (2003) 455
9. Benkert A., Scheller F.W., Schoessler W., Micheel B., and Warsinke A. Size exclusion redox-labeled immunoassay (SERI) - A new format for homogeneous amperometric creatinine determinations. Electroanalysis 12 (2000) 1318
10. Benkert A., Scheller F.W., Schössler W., Hentschel Ch., Micheel B., Behrsing O., Scharte G., Stöcklein W., and Warsinke A. Development of a creatinine ELISA and an amperometric antibody-based creatinine sensor with a detection limit in the nanomolar range. Anal. Chem. 72 (2000) 916
11. Berezin I.V., Bogdanovskaya V.A., Tarasevich M.R., Varfolomeev S.D., and Yaropolov A.I. Bioelectrocatalysis, Equilibrium oxygen potential in the presence of Laccase. Doklady Akademii Nauk SSSR 240 (1978) 615
12. + and NADH. Anal. Biochem. 179 (1989) 382
13. Berggren C., and Johansson G. Capacitance measurements of antibody-antigen interactions in a flow system. Anal. Chem. 69 (1997) 3651
14. Bergveld P. A critical evaluation of direct electrical protein detection methods. Biosens. Bioelectron. 6 (1991) 55
15. Bier F.F., Ehrentreich-Förster E., Bauer Ch., and Scheller F.W. High sensitive Competitive immunodetection of 2,4-dichlorophenoxyacetic acid using enzymatic amplification with electrochemical detection. Fresen. J. Anal. Chem. 354 (1996) 861
16. Bier F.F., Förster E., Makower A., and Scheller F.W. An enzymatic amplification cycle for highly sensitive immunoassay. Anal. Chim. Acta, 328 (1996) 27
17. Bier F.F., Kleinjung F., Ehrentreich-Förster E., and Scheller F.W. Changing functionality of surfaces by directed self-assembly using oligonucleotides - The oligo tag. BioTechniques 27 (1999) 752
18. Blake C., and Gould B.J. Use of enzymes in immunoassay techniques - A review. Analyst 109 (1984) 533
19. Bless N.M., Smith D., Charlton J., Czermak B.J., Schmal H., Friedl H.P., and Ward P.A. Protective effects of an aptamer inhibitor of neutrophil elastase in lung inflammatory injury. Curr. Biol. 7 (1997) 877
20. Blonder R., Katz E., Cohen Y., Itzhak N., Riklin A., and Willner I. Application of redox enzymes for probing the antigen-antibody association at monolayer interfaces: development of amperometric immunosensor electrodes. Anal. Chem. 68 (1996) 3151
21. Bordes A.L., Limoges B., Brossier P., and Degrand C. Simultaneous homogeneous immunoassay of phenytoin and phenobarbital using a nafion-loaded carbon paste electrode and two redox cationic labels. Anal. Chim. Acta 356 (1997) 195
22. Bordes A.L., Schöllhorn B., Limoges B., and Degrand C. Simultaneous detection of three drugs labeled by cationic metal complexes at a nafion-loaded carbon paste electrode. Talanta 48 (1999) 201
23. Buckley E., Smyth M.R., Heineman W.R., and Halsall H.B. Some recent developments in electrochemical immunoassays. Anal. Proceed. 26 (1989) 5
24. Campanella L., Attioli R., Colapicchioni C., and Tomassetti M. New amperometric and potentiometric immunosensors for anti-human immunoglobulin G determinations. Sens. Actuat. B 55 (1999) 23
25. Chinnapen D.J., and Sen D. Hemin-stimulated docking of cytochrome c to a hemin-DNA aptamer complex. Biochemistry 41 (2002) 5202
26. Cho J.S., Lee Y.J., Shin K.S., Jeong S., Park J., and Lee S.W. In vitro selection of specific RNA aptamers for the NFAT DNA binding domain. Mol. Cells, 18 (2004) 17
27. Convery M.A., Rowsell S., Stonehouse N.J., Ellington A.D., Hirao I., Murray J.B., Peabody D.S., Phillips S.E., and Stockley P.G. Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution. Nat. Struct. Biol. 5 (1998) 133
28. Dai Z., Yan F., Chen J., and Ju H. Reagentless amperometric immunosensors based on direct electrochemistry of horseradish peroxidase for determination of carcinoma antigen-125. Anal. Chem. 75 (2003) 5429
29. Di Gleria K., Hill H.A.O., McNeil C.J., and Green M.J. Homogeneous ferrocene-mediated amperometric immunoassay. Anal. Chem. 58 (1986) 1203
30. Dove A. Proteomics: Translating genomics into products?. Nat. Biotechnol. 17 (1999) 233
31. Ducey M.W., Smith A.M., Guo X., and Meyerhoff M.E. Competitive nonseparation electrochemical enzyme binding immunoassay (NEEIA) for small molecule detection. Anal. Chim. Acta 357 (1997) 5
32. Ekins R. A shadow over immunoassay. Nature 340 (1989) 256
33. Ekins, R., Chu, and F. Microspot, array-based, multianalyte binding assays: The ultimate microanalytical Technology?. In: Price C.P., and Newman D.J. (Eds). Principles and Practice of Immunoassay (1997), Macmillan Reference Ltd, London 625-646
34. Ellington A.D., and Szostak J. In vitro selection of RNA molecules that bind specific ligands. Nature 346 (1990) 818
35. Engel L., and Baumann W. Direct potentiometric immunoelectrodes. 4. An immunoelectrode for the trace-level determination of atrazine by separated incubation and potential measurement steps. Fresen. J. Anal. Chem. 349 (1994) 447
36. Eremenko A.V., Bauer C.G., Makower A., Kanne B., Baumgarten H., and Scheller F.W. The development of a non-competitive immunoenzymometric assay of cocaine. Anal. Chim. Acta, 358 (1998) 5
37. Frew J.E., Foulds N.C., Wilshere J.M., Forrow N.J., and Green M.J. Measurement of alkaline phosphatase activity by electrochemical detection of phosphate esters. Electroanal. Chem. 266 (1989) 309
38. Frey A., Hofmann F., Peters R., Holzapfl B., Schienle M., Paulus C., Schindler-Bauer P., Kuhlmeier D., Krause J., Eckstein G., and Thewes R. Yiled Evaluation of gold sensor electrodes used for fully electronic DNA detection arrays on CMOS. Microelectron. Reliab. 42 (2002) 1801
39. Fukuda K., Vishnuvardhan D., Sekiya S., Hwang J., Kakiuchi N., Taira K., Shimotohno K., Kumar P.K., and Nishikawa S. Isolation and characterization of RNA aptamers specific for the Hepatitis C virus nonstructural protein 3 protease. Eur. J. Biochem. 267 (2000) 3685
40. Gal S.W., Amontov S., Urvil P.T., Vishnuvardhan D., Nishikawa F., Kumar P.K., and Nishikawa S. Selection of a RNA aptamer that binds to human activated protein C and inhibits its protease function. Eur. J. Biochem. 252 (1998) 553
41. Gebbert A., Alvarez-Icasa M., Stöcklein W., and Schmid R.D. Real-time monitoring of immunochemical interactions with a tantalum capacitance flow-through cell. Anal. Chem. 64 (1992) 997
42. Gebbert A., Alvarez-Icasa M., Peters H., Jäger V., Bilitewski U., and Schmid R.D. Online monitoring of monoclonal-antibody production with regenerable flow-injection immuno systems. J. Biotech. 32 (1994) 213
43. Ghindilis A.L., Atanasov P., and Wilkins E. Potentiometric immunoelectrode for fast assay based on direct electron transfer catalyzed by peroxidase. Sensors Actuators B 34 (1996) 528
44. Ghindilis A.L., Makower A., Bauer C.G., Bier F.F., and Scheller F.W. Picomolar determination of p-aminophenol and catecholamines based on recycling enzyme amplification. Anal. Chim. Acta 304 (1995) 25-31
45. Ghindilis A.L., Makower A., and Scheller F.W. Nanomolar determination of the ferrocene derivatives using a recycling enzyme electrode development of a redox label immunoassay. Anal. Lett. 28 (1995) 1
46. Ghindilis A.L., Skorobogat'ko O.V., Gavrilova V.P., and Yaropolov A.I. A new approach to the construction of potentiometric immunosensors. Biosens. Bioelectron. 7 (1992) 301
47. Ghindilis A.L., Skorobogat'ko O.V., and Yaropolov A.I. Immunopotentiometric electrodes based on bioelectrocatalysis in the absence of mediators. Biomed. Sci. 2 (1991) 520
48. Gothoh M., Tamiya E., Momoi M., Kagawa Y., and Karube I. Acetylcholine sensor based on ion sensitive field-effect transistor and acetylcholine receptor. Anal. Lett. 20 (1987) 857
49. Grant S., Davis F., Pritchard J.A., Law K.A., Higson S.P.J., and Gibson T.D. Label-less and reversible immunosensor assay based upon an electrochemical current-transient protocol. Anal. Chim. Acta 495 (2003) 21
50. Green L.S., Jellinek D., Jenison R., Ostman A., Heldin C.-H., and Janjic N. Inhibitory DNA ligands to platelet-derived growth factor B-chain. Biochemistry 35 (1996) 14413
51. Grennan K., Strachan G., Porter A.J., Killard A.J., and Smyth M.R. Atrazine analysis using an amperometric immunosensor based on single-chain antibody fragments and regeneration-free multi-calibrant measurement. Anal. Chim. Acta 500 (2003) 287
52. Harlow E., and Lane D. Antibodies: A laboratory manual (1988), Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
53. Harris B. Exploiting antibody-based technologies to manage environmental pollution. Trends Biotechnol. 17 (1999) 290
54. Hesselberth J.R., Miller D., Robertus J., and Ellington A.D. In vitro selection of RNA molecules that inhibit the activity of ricin A-chain. J. Biol. Chem. 275 (2000) 4937
55. Hicke B.J., Marion C., Chang Y.F., Gould T., Lynott C.K., Parma D., Schmidt P.G., and Warren S. Tenascin-C aptamers are generated using tumor cells and purified protein. J. Biol. Chem. 276 (2001) 48644
56. Hintsche R., Paeschke M., Uhlig A., and Seitz R. Microbiosensors using electrodes made in Si-technology. In: Scheller F.W., Schubert F., and Fedrowitz J. (Eds). Frontiers in Biosensorics I (1997), Birkhäuser, Basel 267-283
57. Hirao I., Harada Y., Nojima T., Osawa Y., Masaki H., and Yokoyama S. In vitro selection of RNA aptamers that bind colicin E3 and structurally resemble the decoding site of 16S ribosomal RNA. Biochemistry 43 (2004) 3214
58. Hirao I., Madin K., Endo Y., Yokoyama S., and Ellington A.D. RNA aptamers that bind to and inhibit the ribosome-inactivating protein, pepocin. J. Biol. Chem. 275 (2000) 4943
59. Hu S.Q., Xie J.W., Xu Q.H., Rong K.T., Shen G.L., and Yu R.Q. A label-free electrochemical immunosensor based on gold nanoparticles for detection of paraoxon. Talanta 61 (2003) 769
60. Ikariyama, Y. and M. Aizawa, 1988, Bioaffinity sensors, Methods in Enzymology, Ed. K. Mosbach, Academic Press Inc., New York, 137, 111-124.
61. Ivnitski D., Wolf T., Solomon B., Fleminger G., and Rishpon J. An amperometric biosensor for real-time analysis of molecular recognition. Bioelectrochem. Bioenerg. 45 (1998) 27
62. Janata J. Immunoelectrode. J. Am. Chem. Soc. 97 (1975) 2914
63. Jenkins S.H., Heineman W.R., and Halsall H.B. Extending the detection limit of solid-phase electrochemical enzyme-immunoassay to the attomole level. Anal. Biochem. 168 (1988) 292
64. Jeon S.H., Kayhan B., Ben-Yedidia T., and Arnon R. A DNA aptamer prevents influenza infection by blocking the receptor binding region of the viral haemagglutinin. J. Biol. Chem. 279 (2004) 48410
65. Jing N., Rando R.F., Pommier Y., and Hogan M.E. Ion selective folding of loop domains in a potent anti-HIV oligonucleotide. Biochemistry 36 (1997) 12498
66. Johansson A., Ellis D.H., Bates D.L., Plumb A.M., and Stanley C.J. Enzyme amplification for immunoassays - Detection limit of 100th of an attomole. J. Immunol. Meth. 87 (1986) 7
67. Kaneki N., Xu Y., Kumari A., Halsall H.B., Heineman W.R., and Kissinger P.T. Electrochemical enzyme immunoassay using sequential saturation technique in a 20-μl capillary: Digoxin as a model analyte. Anal. Chim. Acta 287 (1994) 253
68. Kassegne S.K., Reese H., Hodko D., Yang J.M., Sarkar K., Smolko D., Swanson P., Raymond D.E., Heller M.J., and Madou M.J. Numerical modeling of transport and accumulation of DNA on electronically active biochips. Sensors and Actuators B 94 1 (2003) 81
69. Keating M.Y., and Rechnitz G.A. Potentiometric digoxin antibody measurements with antigen ionophore based membrane electrodes. Anal. Chem. 56 (1984) 801
70. Keay R.W., and McNeil C.J. Separation-free electrochemical immunosensor for rapid determination of atrazine. Biosens. Bioelectron. 13 (1998) 963
71. Kelly S.O., and Barton J.K. Electron transfer between bases in double helical DNA. Science 283 (1999) 375
72. Kensch O., Connolly B.A., Steinhoff H.J., McGregor A., Goody R.S., and Restle T. HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity. J. Biol. Chem. 275 (2000) 18271
73. Key G., Schreiber A., Feldbrügge R., McNeil C.J., Joergensen P., Pelsers M.M.A.L., Glatz J.F.C., and Spener F. Multicenter evaluation of an amperometric immunosensor for plasma fatty acid-binding protein: An early marker for acute myocardial infarction. Clin. Biochem. 32 (1999) 229
74. Kirby R., Cho E.J., Gehrke B., Bayer T., Park Y.S., Neikirk D.P., McDevitt J.T., and Ellington A.D. Aptamer-based sensor arrays for the detection and quantitation of proteins. Anal. Chem. 76 (2004) 4066
75. Kleinjung F., Klussmann S., Erdmann V.A., Scheller F.W., Fuerste J.P., and Bier F.F. High-affinity RNA as a recognition element in a biosensor. Anal. Chem. 70 (1998) 328
76. Klug S.J., Huttenhofer A., and Famulok M. In vitro selection of RNA aptamers that bind special elongation factor SelB, a protein with multiple RNA-binding sites, reveals one major interaction domain at the carboxyl terminus. RNA 5 (1999) 1180
77. Kulys J., Razumas V., and Malinauskas A. Electrochemical oxidation of catechol and p-aminophenol esters in the presence of hydrolases. Bioelectrochem. Bioenerg. 7 (1980) 11
78. Landsteiner K., and van der Scheer J. Serological differentiation of steric isomers. J. Exp. Med. 48 (1928) 315
79. Lee M., and Walt D.R. A fibre-optic microarray biosensor using aptamers as receptors. Anal. Biochem. 282 (2000) 142
80. Lu B., Iwuoha E.I., Smyth M.R., and O'Kennedy R. Development of an "electrically wired" amperometric immunosensor for the determination of biotin based on a non-diffusional redox osmium polymer film containing an antibody to the enzyme label horseradish peroxidase. Anal. Chim. Acta 345 (1997) 59
81. Lu B., Iwuoha E.I., Smyth M.R., and O'Kennedy R. Development of an amperometric immunosensor for horseradish peroxidase (HRP) involving a non-diffusional osmium redox polymer co-immobilised with anti-HRP antibody. Anal. Comm. 34 (1997) 21
82. Lupold S.E., Hicke B.J., Lin Y., and Coffey D.S. Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res. 62 (2002) 4029
83. Makower, A., C.G. Bauer, A. Ghindilis and F.W. Scheller, 1994. Sensitive detection of cocaine by combining conjugate displacement and an enzyme substrate recycling sensor, Biosensors 94, Proceedings of the 3rd World Congress on Biosensors, Ed. T. Turner, Elsevier Advanced Technology, Oxford, Poster 3.27.
84. Marko-Varga G., Emneus J., Gorton L., and Ruzgas T. Development of enzyme-based amperometric sensors for the determination of phenolic compounds. Trends Anal. Chem. 14 (1995) 319
85. Matthiasson B., and Nilsson H. Enzyme immunoelectrode - assay of human serum albumin and insulin. FEBS Lett. 78 (1977) 251
86. McCauley T.G., Hamaguchi N., and Stanton M. Aptamer-based biosensor arrays for detection and quantification of biological macromolecules. Anal. Biochem. 319 2 (2003) 244
87. McGregor A., Murray J.B., Adams C.J., Stockley P.G., and Connolly B.A. Secondary structure mapping of an RNA ligand that has high affinity for the MetJ repressor protein and interference modification analysis of the protein-RNA complex. J. Biol. Chem. 274 (1999) 2255
88. McNeil C.J., Athey D., and Ho W.O. Direct electron transfer bioelectronic interfaces: Application to clinical analysis. Biosens. Bioelectron. 10 (1995) 75
89. Meusel M., Renneberg R., Spener F., and Schmitz G. Development of heterogeneous amperometric immunosensor for the determination of apolipoprotein E in serum. Biosens. Bioelectron. 10 (1995) 577
90. Milligan C., and Ghindilis A. Laccase based sandwich scheme immunosensor employing mediatorless electrocatalysis. Electroanalysis 14 (2002) 415
91. Mirhabibollahi B., Brooks J.L., and Kroll R.G. An improved amperometric immunosensor for the detection and enumeration of protein A-bearing Staphylococcus aureus. Lett. Appl. Microbiol. 11 (1990) 119
92. Mirhabibollahi B., Brooks J.L., and Kroll R.G. Development and performance of an enzyme-linked amperometric immunosensor for the detection of staphylococcus aureus in foods. J. Appl. Bacteriol. 68 (1990) 577
93. Navratilova I., and Skladal P. The immunosensors for measurement of 2,4-D based on electrochemical impedance spectroscopy. Bioelectrochemistry 62 (2004) 11
94. Nebling E., Grunwald T., Albers J., Schäfer P., and Hintsche R. Electrical detection of viral DNA using ultramicroelectrode arrays. Anal. Chem. 76 (2004) 689
95. Newman, A.L., K.W. Hunter and W.D. Stanbro, 1986, Proceedings of the 2nd International Meeting on Chemical Sensors, Bordeaux, 596.
96. Niemeyer C.M., Sano T., Smith C.L., and Cator C.R. Oligonucleotide-directed self-assembly of proteins: Semisynthetic DNA-streptavidin hybrid molecules as connectors for the generation of macroscopic arrays and the construction of supramolecular bioconjugates. Nucleic Acid Res 22 (1994) 5530
97. Niwa O., Morita M., and Tabei H. Highly sensitive and selective voltammetric detection of dopamine with vertically separated interdigitated array electrodes. Electroanalysis 3 (1991) 163
98. Niwa O., Xy Y., Halsall B.H., and Heineman W.R. Small-volume voltammetric detection of 4-aminophenol with integrated array electrodes and its application to electrochemical enzyme immunoassay. Anal. Chem. 65 (1993) 1559
99. Ogert R.A., Kusterbeck A.W., Gregory A., Wemhoff R.B., Burke R., and Ligler F.S. Detection of cocaine using the flow immunosensor. Anal. Lett. 25 (1992) 1999
100. Olson J.D., Panfili P.R., Armenta R., Fremmel M.B., Merrick H., Gumperz J., Goltz M., and Zuk R.F. A silicon sensor - based filtration immunoassay using biotin-mediated capture. J. Immunol. Meth. 134 (1990) 71
101. Padeste C., Grubelnik A., and Tiefenauer L. Amperometric immunosensing using microperoxidase MP-11 antibody conjugates. Anal. Chim. Acta, 374 (1998) 167
102. Pfeifer U., and Baumann W. Direct potentiometric immunoelectrodes. 1. Immobilization of proteins on titanium wire electrodes. Fresen. J. Anal. Chem. 343 (1992) 541
103. Pileur F., Andreola M.L., Dausse E., Michel J., Moreau S., Yamada H., Gaidamakov S.A., Crouch R.J., Toulme J.J., and Cazenave C. Selective inhibitory DNA aptamers of the human RNase H1. Nucleic Acid Res. 31 (2003) 5776
104. Potyrailo R.A., Conrad R.C., Ellington A.D., and Hieftje G.M. Adapting selected nucleic acid ligands (aptamers) to biosensors. Anal. Chem. 70 (1998) 3419
105. Price C.P. Progress in immunoassay technology. Clin. Chem. Lab. Med. 36 (1998) 341
106. Proske D., Hofliger M., Soll R.M., Beck-Sickinger A.G., and Famulok M. A Y2 receptor mimetic aptamer directed against neuropeptide Y. J. Biol. Chem. 277 (2002) 11416
107. Raba J., and Motolla H.A. Online enzymatic amplification by substrate cycling in a dual bioreactor with rotation and amperometric detection. Anal. Biochem. 220 (1994) 297
108. Renneberg R., Schoessler W., and Scheller F. Amperometric enzyme sensor-based enzyme immunoassay for factor VIII-related antigen. Anal. Lett. 16 (1983) 1279
109. Riepl M., Mirsky V.M., Novotny I., Tvarozek V., Rehacek V., and Wolfbeis O.S. Optimization of capacitive affinity sensors: Drift suppression and signal amplification. Anal. Chim. Acta 392 (1999) 77
110. Rishpon J., and Ivnitski D. An amperometric enzyme-channeling immunosensor. Biosens. Bioelectron. 12 (1997) 195
111. Rhodes A., Deakin A., Spaull J., Coomber B., Aitken A., Life P., and Rees S. The generation and characterization of antagonist RNA aptamers to human oncostatin M. J. Biol. Chem. 275 (2000) 28555
112. Robinson G.A., Cole V.M., and Forrest G.C. A homogeneous electrode-based bioelectrochemical immunoassay for human chorionic gonadotrophin. Biosensors 3 (1987/1988) 147
113. Romero F.J.M., Stiene M., Kast R., Luque de Castro M.D., and Bilitewski U. Application of screen-printed electrodes as transducers in affinity flow-through sensor systems. Biosens. Bioelectron. 13 (1998) 1107
114. Rubenstein K.E., Schneider R.S., and Ullman E.F. Homogeneous enzyme immunoassay - New immunochemical technique. Biochem. Biophys. Res. Commun. 47 (1972) 846
115. Ruzgas T., Csöregi A., Emneus J., Gorton L., and Marko-Varga G. Peroxidase-modified electrodes: Fundamentals and application. Anal. Chim. Acta 330 (1996) 123
116. Sadik, O.A., Van Emon, J.M., 1997. Designing immunosensors for environmental monitoring, Chem. Tech. 38-46.
117. Santadreu M., Alegret A., and Fabregas E. Determination of beta-HCG using amperometric immunosensors based on a conducting immunocomposite. Anal. Chim. Acta 396 (1999) 181
118. Sayer N., Ibrahim J., Turner K., Tahiri-Alaoui A., and James W. Structural characterization of a 2′F-RNA aptamer that binds a HIV-1 SU glycoprotein, gp 120. Biochem. Biophys. Res. Commun. 293 (2002) 924
119. Scheller F.W., Bauer C.G., Makower A., Wollenberger U., Warsinke A., and Bier F.F. Immunoassays using enzymatic amplification electrodes. In: Gizeli E., and Lowe C.R. (Eds). Biomolecular Sensors (2002), Taylor and Francis, London 207-238
120. Self, C.H., 1981, European Patent Appl. 80303478.4 (15.04.1981).
121. Sergeyeva T.A., Soldatkin A.P., Rachkov A.E., Tereschenko M.I., Piletsky S.A., and El'skaya A.V. Beta-lactamase label-based potentiometric biosensor for alpha-2 interferon detection. Anal. Chim. Acta 390 (1999) 73
122. Srisawat C., and Engelke D.R. Streptavidin aptamers: Affinity tags for the study of RNAs and ribonucleoproteins. RNA 7 (2001) 632
123. Stelzle M., Durr M., and Nisch W. On-chip electrophoresis accumulation of DNA-oligomers and streptavidin. Fresen. J. Anal. Chem. 371 (2001) 112
124. Susmel S., Guilbault G.G., and O'Sullivan C.K. Demonstration of label-less detection of food pathogens using electrochemical redox probe and screen printed gold electrodes. Biosens. Bioelectron. 18 (2003) 881
125. Takeno H., Yamamoto S., Tanaka T., Sakano Y., and Kikuchi Y. Selection of an RNA molecule that specifically inhibits the protease activity of subtilisin. J. Biochem. (Tokyo) 125 (1999) 1115
126. Tang H.T., Lunte C.F., Halsall H.B., and Heineman W.R. -Aminophenyl phosphate - An improved substrate for electrochemical enzyme immunoassay. Anal. Chim. Acta 214 (1988) 187
127. + /NADH using glycerol dehydrogenase and diaphorase with amperometric detection. Anal. Lett. 28 (1995) 2595
128. Tarasewich M.R. Chapter 4: Bioelectrocatalysis. Comprehensive Treatise of Electrochemistry. In: Srinivasan S., Chizmadzhev Y.A., Bockris J.OM., Conway B.E., and Yeager E. (Eds). 10th Bioelectrochemistry (1985), Plenum Press, New York 275
129. Tasset D.M., Kubik M.F., and Steiner W. Oligonucleotide inhibitors of human thrombin that bind distinct epitopes. J. Mol. Biol. 272 (1997) 688
130. Thévenot D.R., Toth K., Durst R.A., and Wilson G.S. Electrochemical biosensors: Recommended definitions and classification. Biosens. Bioelectron. 16 (2001) 121
131. Thomas M., Chedin S., Carles C., Riva M., Famulok M., and Sentenac A. Selective targeting and inhibition of yeast RNA polymerase II by RNA aptamers. J. Biol. Chem. 272 (1997) 27980
132. Tiefenauer L.X., Kossek S., Padeste C., and Thiébaud P. Towards amperometric immunosensor devices. Biosens. Bioelectron. 12 (1997) 213
133. Tuerk C., and Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249 (1990) 505
134. Wehmeyer K.R., Halsall H.B., Heineman W.R., Volle C.D., and Chen I.W. Competitive heterogeneous enzyme immunoassay for digoxin with electrochemical detection. Anal. Chem. 58 (1986) 135
135. Weiss S., Proske D., Neumann M., Groschup M.H., Kretzschmar H.A., Famulok M., and Winnacker E.L. RNA aptamers specifically interact with the prion protein PrP. J. Virol. 71 (1997) 8790
136. Weller M.G., Schuetz A.J., Winklmair M., and Niessner R. Highly parallel affinity sensor for the detection of environmental contaminants in water. Anal. Chim. Acta 393 (1999) 29
137. Wendzinski F., Gründig B., Renneberg R., and Spener F. Highly sensitive determination of hydrogen peroxide and peroxidase with tetrethiafulvalene-based electrodes and the application in immunosensing. Biosens. Bioelectron. 12 (1997) 43
138. Wiegand T.W., Williams P.B., Dreskin S.C., Jouvin M.H., Kinet J.P., and Tasset D. High-affinity oligonucleotide ligands to human IgE inhibit binding to Fc epsilon receptor I. J. Immunol. 157 (1996) 221
139. Wingren C., Ingvarsson J., Lindstedt M., and Borrebaeck C.A.K. Recombinant antibody microarrays - a viable option?. Nat. Biotechnol. 21 (2003) 223
140. Wollenberger U., Paeschke M., and Hintsche R. Interdigitated array microelectrodes for the determination of enzyme activities. Analyst 119 (1994) 1245
141. Wollenberger U., Schubert F., Pfeiffer D., and Scheller F.W. Enhancing biosensor performance using multi-enzyme systems. Trends Biotechnol. 11 (1993) 255
142. Yalow R.S., and Berson S.A. Assay of plasma insulin in human subjects by immunological methods. Nature 184 (1959) 1648
143. Yamamoto R., Baba T., and Kumar P.K. Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1. Genes Cells 5 (2000) 389
144. Yang L., Li Y., and Erf G.F. Interdigitated array microelectrod-based electrochemical impedance immunosensor for detection of E.coli O157:H7. Anal. Chem. 76 (2004) 1107-1113