Highly sensitive determination of hydrogen peroxide and peroxidase with tetrathiafulvalene-based electrodes and the application in immunosensing

Biosensors and Bioelectronics

Volumn 12, Issue 1, 1997, Pages 43-52

  Wendzinski, Frank ^a,b   Gründig, Bernd ^a   Renneberg, Reinhard ^a   Spener, Friedrich ^a,b  

^a ICB Institut fur Chemo und Biosensorik GmbH   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Amperometric immunosensor; Flow through system; Graphite electrode; Horseradish peroxidase; Hydrogen peroxide; Mediator electrode; Tetrathiafulvalene

Indexed keywords

AMPEROMETRIC SENSORS; ELECTROCHEMICAL ELECTRODES; ELECTROCHEMICAL SENSORS; ENZYME KINETICS; ENZYME SENSORS; GRAPHITE ELECTRODES; HYDROGEN PEROXIDE; REDOX REACTIONS;

CALOMEL ELECTRODES; HORSERADISH PEROXIDASE (HRP); MEDIATOR ELECTRODES; TETRATHIAFULVALENE (TTF) MODIFIED GRAPHITE ELECTRODES;

IMMUNOSENSORS;

HYDROGEN PEROXIDE; PEROXIDASE; TETRATHIAFULVALENE DERIVATIVE;

AMPEROMETRY; ARTICLE; BIOSENSOR; ELECTRODE;

ARMORACIA RUSTICANA; ORYCTOLAGUS CUNICULUS;

EID: 0343397716     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/0956-5663(96)89088-9     Document Type: Article

References (33)

1. Bifulco, L., Cammaroto, C., Newman, J. D. & Turner, A. P. F. (1994). TTF-modified biosensors for hydrogen peroxide. Anal. Lett., 27, 1443-1452.
2. Cardosi, M. F. (1987). Development of novel biosensors. Anal. Proc., 24, 143-145.
3. Cardosi, M. F., Birch, S. W., Smith, B. M. & Johannsson, A. (1989). An enzyme-amplified electrochemical immunoassay for thyrotropin. Electroanalysis, 1, 297-304.
4. Csöregi, E., Gorton, L., Marko-Vaga, G., Tüdös, A. J. & Kok, W. T. (1994). Peroxidase-modified carbon fiber microelectrodes in flow-through detection of hydrogen peroxide and organic peroxides. Anal. Chem., 66, 3604-3610.
5. 1-acid glycoprotein. Anal. Chem., 56, 2355-2360.
6. Duan, D. & Meyerhoff, M. E. (1995). Separation free sandwich enzyme immunoassays using microporous gold electrodes and self-assembled monolayer/immobilized capture antibodies. Anal. Chem., 66, 1369-1377.
7. Eggers, H. M., Halsall, H. B. & Heinemann, W. R. (1982). Enzyme immunoassay with flow amperometric detection of NADH. Clin. Chem., 28, 1848-1851.
8. Frew, J. E., Harmer, M. A., Hill, H. A. O. & Libor, S. I. (1986). A method for estimation of hydrogen peroxide based on mediated electron transfer reactions of peroxidases at electrodes. J. Electroanal. Chem., 201, 1-10.
9. Gleria, K. di, Hill, H. A. O., McNeil, C. J. & Green, M. J. (1986). Homogeneous ferrocene-mediated amperometric immunoassay. Anal. Chem., 58, 1203-1205.
10. Gründig, B. & Krabisch, C. (1989). Electron mediator-modified electrode for the determination of glucose in fermentation media. Anal. Chim. Acta, 222, 75-81.
11. Gründig, B., Strehlitz, B., Krabisch, C., Thielemann, H., Kotte, H., Gomoll, M., Kopinke, H. & Pitzler, R. (1992). The use of redox mediators for amperometric biosensors. In Biosensors: Fundamentals, Technologies and Applications, GBF Monographs, Vol. 17. VCH, Weinheim, pp. 275-285.
12. Gunasingham, H., Tan, C.-H. & Aw, T.-C. (1990). Comparative study of first-, second- and third-generation amperometric glucose enzyme electrodes in continuous-flow analysis of undiluted whole blood. Anal. Chim. Acta, 234, 321-330.
13. Gyss, C. & Bourdillon, C. (1987). Enzymatic electrocatalysis as a strategy for electrochemical detection in heterogeneous immunoassays. Anal. Chem., 59, 2350-2355.
14. Heinemann, W. R. & Halsall, H. B. (1985). Strategies for electrochemical immunoassay. Anal. Chem., 57, 1321A-1331A.
15. Holland, V. R., Saunders, B. C., Rose, F. L. & Walpole, A. L. (1974). A safer substitute for benzidine in the detection of blood. Tetrahedron, 30, 3299-3302.
16. Jaeger, C. D. & Bard, A. J. (1979). Electrochemical behaviour of tetrathiafulvalene-tetracyanoquinodimethane electrodes in aqueous media. J. Am. Chem. Soc., 101, 1690-1699.
17. Kaláb, T. & Skládar, P. (1995). A disposable amperometric immunosensor for 2,4-dichlorophenoxy-acetic acid. Anal. Chim. Acta, 304, 361-368.
18. Korell, U. & Spichiger, U. E. (1993). Membraneless immobilization of xanthine oxidase on organic conducting salt/silicone oil electrodes. Electroanalysis, 5, 869-876.
19. Korell, U. & Spichiger, U. E. (1994). Novel membraneless amperometric peroxide biosensor based on a tetrathiafulvalene-p-tetracyanoquinodimethane electrode. Anal. Chem., 66, 510-515.
20. Kulys, J. J. (1981). Development of new analytical systems based on biocatalysers. Enzyme Microb. Technol., 3, 342-352.
21. Kulys, J. J., Simkeviciene, V. & Higgins, I. J. (1992). Concerning the toxicity of two compounds used as mediators in biosensor devices: 7,7,8,8-tetracyanoquinodimethane (TCNQ) and tetrathiafulvalene (TTF). Biosensors & Bioelectronics, 7, 495-501.
22. Másson, M., Liu, Z., Haruyama, T., Kobatake, E., Ikariyama, Y. & Aizawa, M. (1995). Immunosensing with amperometric detection, using galactosidase as label and p-aminophenyl-β-D-galactopyr-anoside as substrate. Anal. Chim. Acta, 304, 353-359.
23. McNeil, C. J., Higgins, I. J. & Bannister, J. V. (1987). Amperometric determination of alkaline phosphatase activity: application to enzyme immunoassay. Biosensors, 3, 199-209.
24. Meusel, M., Renneberg, R., Spener, F. & Schmitz, G. (1995). Development of a heterogeneous amperometric immunosensor for the determination of apolipoprotein E in serum. Biosensors & Bioelectronics, 10, 577-586.
25. O'Daly, J. P., Zhao, J., Brown, P. A. & Henkens, R. W. (1992). Electrochemical enzyme immunoassay for detection of toxic substances. Enzyme Microb. Technol., 14, 299-302.
26. Schubert, F., Saini, S. & Turner, A. P. F. (1991). Mediated amperometric enzyme electrode incorporating peroxidase for the determination of hydrogen peroxide in organic solvents. Anal. Chim. Acta, 245, 133-138.
27. Suzawa, T., Ikariyama, Y. & Aizawa, M. (1994). Multi-labeling of ferrocenes to a glucose oxidase-digoxin conjugate for the development of a homogeneous electroenzymatic immunoassay. Anal. Chem., 66, 3889-3894.
28. Turner, A. P. F., Hendry, S. P. & Cardosi, M. F. (1987). Tetrathiafulvalene: a new mediator for amperometric biosensors. In World Biotech. Report 1. Online Publications, London, pp. 125-137.
29. Vreeke, M., Maidan, R. & Heller, A. (1992). Hydrogen peroxide and β-nicotinamide adenine dinucleotide sensing amperometric electrodes based on electrical connection of horseradish peroxidase redox centers to electrodes through a three-dimensional electron relaying polymer network. Anal. Chem., 64, 3084-3090.
30. Vreeke, M., Rocca, P. & Heller, A. (1995). Direct electrical detection of dissolved biotinylated horse-radish peroxidase, biotin, and avidin. Anal. Chem., 67, 303-306.
31. Wright, J. D., Rawson, K. M., Ho, W. O., Athey, D. & McNeil, C. J. (1995). Specific binding assay for biotin based on enzyme channelling with direct electron transfer electrochemical detection using horseradish peroxidase. Biosensors & Bioelectronics, 10, 495-500.
32. Yao, T., Sato, M., Kobayashi, Y. & Wasa, T. (1985). Amperometric assays of total and free cholesterol in serum by the combined use of immobilized cholesterol esterase and cholesterol oxidase reactors and peroxidase electrode in a flow injection system. Anal. Biochem., 149, 387-396.
33. Zhao, S. & Luong, J. H. T. (1993). Stable mediated amperometric biosensors using a graphite electrode embedded with tetrathiafulvalene in silicone oil. Biosensors & Bioelectronics, 8, 483-491.