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Volumn 252, Issue 3, 1998, Pages 553-562

Selection of a RNA aptamer that binds to human activated protein C and inhibits its protease function

Author keywords

Activated protein C; Aptamer; In vitro selection; RNA; Trypsin like serine protease

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 9A; OLIGONUCLEOTIDE; THROMBIN;

EID: 0032521665     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2520553.x     Document Type: Article
Times cited : (55)

References (33)
  • 1
    • 0024443885 scopus 로고
    • Amplification, mutation and selection of catalytic RNA
    • Joyce, G. F. (1989) Amplification, mutation and selection of catalytic RNA, Gene 82, 83-87.
    • (1989) Gene , vol.82 , pp. 83-87
    • Joyce, G.F.1
  • 2
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to Bacteriophage T4 DNA polymerase
    • Tuerk, C. & Gold, L. (1990) Systematic evolution of ligands by exponential enrichment: RNA ligands to Bacteriophage T4 DNA polymerase, Science 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 3
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington, A. & Szostak, J. W. (1990) In vitro selection of RNA molecules that bind specific ligands, Nature 346, 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.1    Szostak, J.W.2
  • 5
  • 6
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock, L. C., Griffin, L. C., Latham, J. A., Vermass, E. H. & Tool, J. J. (1992) Selection of single-stranded DNA molecules that bind and inhibit human thrombin, Nature 355, 564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermass, E.H.4    Tool, J.J.5
  • 9
    • 0028641549 scopus 로고
    • Modified RNA sequence pools for in vitro selection
    • Lin, Y., Qiu, Q., Gill, S. C. & Jayasena, S. D. (1994) Modified RNA sequence pools for in vitro selection. Nucleic Acids Res. 22, 5229-5234.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5229-5234
    • Lin, Y.1    Qiu, Q.2    Gill, S.C.3    Jayasena, S.D.4
  • 10
    • 0028826936 scopus 로고
    • Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition
    • Lin, Y., Padmapriya, A., Morden, K. M. & Jayasena, S. D. (1995) Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition, Proc. Natl Acad. Sci. USA 92, 11044-11048.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 11044-11048
    • Lin, Y.1    Padmapriya, A.2    Morden, K.M.3    Jayasena, S.D.4
  • 11
    • 0028323166 scopus 로고
    • Structural basis for type I and type II deficiencies of antithrombotic plasma protein C: Patterns revealed by three-dimensional molecular modeling of mutations of the protease domain
    • Greengard, J. S., Fisher, C. L., Villoutreix, B. & Griffin, J. H. (1994) Structural basis for type I and type II deficiencies of antithrombotic plasma protein C: Patterns revealed by three-dimensional molecular modeling of mutations of the protease domain. Proteins 18, 367-380.
    • (1994) Proteins , vol.18 , pp. 367-380
    • Greengard, J.S.1    Fisher, C.L.2    Villoutreix, B.3    Griffin, J.H.4
  • 12
    • 0028204534 scopus 로고
    • Models of the serine protease domain of the human antithrombotic plasma factor activated protein C and its zymogen
    • Fisher, C. L., Greengard, J. S. & Griffin, J. H. (1994) Models of the serine protease domain of the human antithrombotic plasma factor activated protein C and its zymogen. Protein Sci. 3, 588-599.
    • (1994) Protein Sci. , vol.3 , pp. 588-599
    • Fisher, C.L.1    Greengard, J.S.2    Griffin, J.H.3
  • 13
    • 10344257566 scopus 로고    scopus 로고
    • Genetic characterization of protein C deficiency in Japanese subjects using a rapid and nonradioactive method for single-strand conformational polymorphism analysis and a model building
    • Miyata, T., Sakata, T., Zheng, Y.-Z., Tsukamoto, H., Umeyama, H., Uchiyama, S., Ikusaka, M., Yoshioka, A., Imanaka, Y., Fujimura, H., Kambayashi, J. & Kato, H. (1996) Genetic characterization of protein C deficiency in Japanese subjects using a rapid and nonradioactive method for single-strand conformational polymorphism analysis and a model building, Thromb. Haemostasis 76, 302-311.
    • (1996) Thromb. Haemostasis , vol.76 , pp. 302-311
    • Miyata, T.1    Sakata, T.2    Zheng, Y.-Z.3    Tsukamoto, H.4    Umeyama, H.5    Uchiyama, S.6    Ikusaka, M.7    Yoshioka, A.8    Imanaka, Y.9    Fujimura, H.10    Kambayashi, J.11    Kato, H.12
  • 14
    • 0018573970 scopus 로고
    • Molecular properties of the Factor V-activating enzyme from Russell's viper venom
    • Kisiel, W. (1979) Molecular properties of the Factor V-activating enzyme from Russell's viper venom, J. Biol. Chem. 254, 12230-12234.
    • (1979) J. Biol. Chem. , vol.254 , pp. 12230-12234
    • Kisiel, W.1
  • 15
    • 0000650903 scopus 로고
    • Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C
    • Esmon, C. T. & Owen, W. G. (1981) Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. Proc. Natl Acad. Sci. USA 78, 2249-2252.
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , pp. 2249-2252
    • Esmon, C.T.1    Owen, W.G.2
  • 16
    • 0017567792 scopus 로고
    • Anticoagulant properties of bovine plasma protein C following activation by thrombin
    • Kisiel, W., Canfield, W. M., Ericsson, L. H. & Davie, E. W. (1977) Anticoagulant properties of bovine plasma protein C following activation by thrombin, Biochemistry 16, 5824-5831.
    • (1977) Biochemistry , vol.16 , pp. 5824-5831
    • Kisiel, W.1    Canfield, W.M.2    Ericsson, L.H.3    Davie, E.W.4
  • 17
    • 0018715761 scopus 로고
    • The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V
    • Walker, F., Sexton, P. W. & Esmon, C. T. (1979) The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V, Biochim. Biophys. Acta 571, 333-342.
    • (1979) Biochim. Biophys. Acta , vol.571 , pp. 333-342
    • Walker, F.1    Sexton, P.W.2    Esmon, C.T.3
  • 18
    • 0020072618 scopus 로고
    • Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme
    • Marlar, R. A., Kleiss, A. J. & Griffin, J. H. (1982) Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme, Blood 59, 1067-1072.
    • (1982) Blood , vol.59 , pp. 1067-1072
    • Marlar, R.A.1    Kleiss, A.J.2    Griffin, J.H.3
  • 19
    • 0021958273 scopus 로고
    • Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity
    • Sakata, Y., Curriden, S., Lawrence, D., Griffin, J. H. & Loskutoff, D. J. (1985) Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity, Proc. Natl Acad. Sci. USA 82, 1121-1125.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 1121-1125
    • Sakata, Y.1    Curriden, S.2    Lawrence, D.3    Griffin, J.H.4    Loskutoff, D.J.5
  • 20
    • 0028940777 scopus 로고
    • Human protein C and activated protein C. Components of the human anticoagulation system
    • Castellino, F. J. (1995) Human protein C and activated protein C. Components of the human anticoagulation system, Trends Cardiovasc. Med. 5, 55-62.
    • (1995) Trends Cardiovasc. Med. , vol.5 , pp. 55-62
    • Castellino, F.J.1
  • 21
  • 22
    • 0029295966 scopus 로고
    • Dissecting protein: Protein interactions between transcription factors with an RNA aptamer
    • Tian, Y., Adya, N., Wagner, S., Giam, C., Green, M. R. & Ellington, A. D. (1995) Dissecting protein: protein interactions between transcription factors with an RNA aptamer, RNA I, 317-326.
    • (1995) RNA , vol.1 , pp. 317-326
    • Tian, Y.1    Adya, N.2    Wagner, S.3    Giam, C.4    Green, M.R.5    Ellington, A.D.6
  • 23
    • 0024806949 scopus 로고
    • Computer prediction of RNA structure
    • Zuker, M. (1989) Computer prediction of RNA structure. Methods Enzymol. 180, 262-288.
    • (1989) Methods Enzymol. , vol.180 , pp. 262-288
    • Zuker, M.1
  • 24
    • 0026599465 scopus 로고
    • Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures
    • Ellington, A. & Szostak, J. W. (1992) Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures, Nature 355, 850-852.
    • (1992) Nature , vol.355 , pp. 850-852
    • Ellington, A.1    Szostak, J.W.2
  • 25
    • 0029138009 scopus 로고
    • RNA aptamers that bind flavin and nicotinamide redox cofactors
    • Lauhon, C. T. & Szostak, J. W. (1995) RNA aptamers that bind flavin and nicotinamide redox cofactors, J. Am. Chem. Soc. 117, 1246-1257.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 1246-1257
    • Lauhon, C.T.1    Szostak, J.W.2
  • 26
    • 0027995790 scopus 로고
    • Isolation of RNA aptamers for biological cofactors by in vitro selection
    • Burgstaller, P. & Famulok, M. (1994) Isolation of RNA aptamers for biological cofactors by in vitro selection, Angew. Chem. Int. Ed. Engl. 33, 1084-1087.
    • (1994) Angew. Chem. Int. Ed. Engl. , vol.33 , pp. 1084-1087
    • Burgstaller, P.1    Famulok, M.2
  • 27
    • 0031576991 scopus 로고    scopus 로고
    • Crystal structure of an alternating octamer r(GUAUGUA)dC with adjacent G · U wobble pairs
    • Biswas, R., Wahl, M. C., Ban, C. & Sundaralingam, M. (1997) Crystal structure of an alternating octamer r(GUAUGUA)dC with adjacent G · U wobble pairs, J. Mol. Biol. 267, 1149-1156.
    • (1997) J. Mol. Biol. , vol.267 , pp. 1149-1156
    • Biswas, R.1    Wahl, M.C.2    Ban, C.3    Sundaralingam, M.4
  • 28
    • 0031577263 scopus 로고    scopus 로고
    • Crystal structure of r(GUGUGUA)dC with tandem G · U/U · G wobble pairs with strand slippage
    • Biswas, R. & Sundaralingam, M. (1997) Crystal structure of r(GUGUGUA)dC with tandem G · U/U · G wobble pairs with strand slippage, J. Mol. Biol. 270, 511-519.
    • (1997) J. Mol. Biol. , vol.270 , pp. 511-519
    • Biswas, R.1    Sundaralingam, M.2
  • 29
    • 0029395440 scopus 로고
    • In vitro selection of RNA-based irreversible inhibitors of human neutrophile elastase
    • Smith, D., Kirschenheuter, G. P., Charlton, J., Guidot, D. M. & Repine, J. E. (1995) In vitro selection of RNA-based irreversible inhibitors of human neutrophile elastase, Chem. & Biol. 2, 741-750.
    • (1995) Chem. & Biol. , vol.2 , pp. 741-750
    • Smith, D.1    Kirschenheuter, G.P.2    Charlton, J.3    Guidot, D.M.4    Repine, J.E.5
  • 31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.