Synthesis and in vitro evaluation of defined HPMA folate conjugates: Influence of aggregation on folate receptor (FR) mediated cellular uptake

Biomacromolecules

Volumn 11, Issue 9, 2010, Pages 2274-2282

  Barz, Matthias ^a,b   Canal, Fabiana ^b   Koynov, Kaloian ^c   Zentel, R ^a   Vicent, María J ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^c MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATE FORMATION; AGGREGATION BEHAVIOR; CANCER CELL LINES; CELL UPTAKE; CELLULAR UPTAKE; COLOCALIZATION; CONFOCAL FLUORESCENCE MICROSCOPY; FLUORESCENCE CORRELATION SPECTROSCOPY; FOLATE CONTENT; FOLATE RECEPTOR; FOLATE-FUNCTIONALIZED; FOLIC ACIDS; HUMAN LUNG; IN-VITRO EVALUATION; INTRACELLULAR LOCALIZATION; LIVE CELL; METHACRYLAMIDES; POLYMER BEARINGS; POLYMER CONJUGATE; RAFT POLYMERIZATION; RECEPTOR-MEDIATED ENDOCYTOSIS; TOTAL CONTENT;

CELL CULTURE; ESTERS; FLUORESCENCE; FLUORESCENCE MICROSCOPY; FLUORESCENCE SPECTROSCOPY; FUNCTIONAL POLYMERS; LIVING POLYMERIZATION; MOLECULAR BIOLOGY; MOLECULAR WEIGHT; ORGANIC ACIDS;

POLYMERS;

FOLATE RECEPTOR; FOLIC ACID; FOLIC ACID N (2 HYDROXYPROPYL)METHACRYLAMIDE CONJUGATE; N (2 HYDROXYPROPYL)METHACRYLAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG SYNTHESIS; DRUG UPTAKE; ENDOCYTOSIS; FLUORESCENCE CORRELATION SPECTROSCOPY; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; POLYMERIZATION; PRIORITY JOURNAL;

CELL LINE, TUMOR; CELL SURVIVAL; FOLATE RECEPTOR 1; FOLIC ACID; HUMANS; LUNG NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; METHACRYLATES; NASOPHARYNGEAL NEOPLASMS; POLYMERIZATION; POLYMERS;

EID: 77956543909     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm100338x     Document Type: Article

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