Influenza A virus polymerase: Structural insights into replication and host adaptation mechanisms

Journal of Biological Chemistry

Volumn 285, Issue 37, 2010, Pages 28411-28417

  Boivin, Stéphane ^a   Cusack, Stephen ^a   Ruigrok, Rob W H ^a   Hart, Darren J ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ORGANIC ACIDS; RNA; TRANSCRIPTION; VIRUSES;

ADAPTATION MECHANISM; C-TERMINAL REGIONS; CAP-BINDING; CELL TYPES; ENDONUCLEASES; HIGH-RESOLUTION STRUCTURES; INFECTED CELLS; INFLUENZA A VIRUS; INFLUENZA VIRUS; INTRINSIC ACTIVITIES; NEW STRUCTURES; NUCLEOCYTOPLASMIC TRANSPORT; POLYMERASE ACTIVITIES; POLYMERIZATION ACTIVITY; RNA INTERFERENCE; RNA PRIMERS; RNA REPLICATION; RNA-DEPENDENT RNA POLYMERASE; STRUCTURAL INSIGHTS; STRUCTURAL STUDIES; SUBUNIT ASSOCIATIONS; SURFACE EXPOSURE; TRANSCRIPTION ACTIVITY; TRANSCRIPTION PROCESS;

POLYMERS;

RIBONUCLEOPROTEIN; RNA DIRECTED RNA POLYMERASE; CAPPED RNA; RNA DIRECTED DNA POLYMERASE; VIRUS RNA;

ADAPTATION; AMINO ACID SEQUENCE; BINDING SITE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBUNIT; GENE MUTATION; HUMAN; INFLUENZA; INFLUENZA VIRUS A; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA REPLICATION; RNA TRANSCRIPTION; SHORT SURVEY; VIRUS CELL INTERACTION; VIRUS VIRULENCE; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; CELL NUCLEUS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETIC TRANSCRIPTION; METABOLISM; PHYSIOLOGY; PROTEIN QUATERNARY STRUCTURE; STRUCTURE ACTIVITY RELATION; VIROLOGY; VIRUS REPLICATION; X RAY CRYSTALLOGRAPHY;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CATALYTIC DOMAIN; CELL NUCLEUS; CRYSTALLOGRAPHY, X-RAY; HUMANS; INFLUENZA A VIRUS; PROTEIN STRUCTURE, QUATERNARY; RNA CAPS; RNA, VIRAL; RNA-DIRECTED DNA POLYMERASE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; VIRUS REPLICATION;

EID: 77956536783     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R110.117531     Document Type: Short Survey

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