Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts

Bone

Volumn 39, Issue 6, 2006, Pages 1290-1301

  Sakai, Hiroaki ^a   Chen, Yan ^a   Itokawa, Takashi ^a   Yu, Kuan ping ^a   Zhu, Mei ling ^a   Insogna, Karl ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cdc42; CSF 1; Osteoclast; PI3 kinase; Rac; Rho; Vav

Indexed keywords

ACTIN; BISPHOSPHONIC ACID DERIVATIVE; COLONY STIMULATING FACTOR 1; COMPLEMENT COMPONENT C3; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOINOSITOL 4,5 BISPHOSPHONATE; PHOSPHOTYROSINE; PROTEIN CDC42; RAC PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VAV PROTEIN; WORTMANNIN;

ANIMAL CELL; ARTICLE; BONE DENSITY; CELL ISOLATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; KNOCKOUT MOUSE; LAMELLIPODIUM; MICROINJECTION; MOUSE; NEWBORN; NONHUMAN; OSTEOCLAST; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANDROSTADIENES; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CDC42 GTP-BINDING PROTEIN; CELLS, CULTURED; CYTOSKELETON; ENZYME INHIBITORS; GUANOSINE TRIPHOSPHATE; HUMANS; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; MODELS, BIOLOGICAL; OSTEOCLASTS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-VAV; PSEUDOPODIA; RAC GTP-BINDING PROTEINS; RATS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 34648844847     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.06.012     Document Type: Article

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