Polycystic ovary syndrome and autoimmunity

European Journal of Internal Medicine

Volumn 21, Issue 5, 2010, Pages 369-371

  Petríková, Jana ^a,b   Lazúrová, Ivica ^a   Yehuda, Shoenfeld ^b,c  

^a L PASTEUR UNIVERSITY HOSPITAL   (Slovakia)

^b SHEBA MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Autoantibodies; Autoimmunity; Hyperandrogenism; PCOS

Indexed keywords

25 HYDROXYVITAMIN D; ANDROGEN; ANTINUCLEAR ANTIBODY; AUTOANTIBODY; DOUBLE STRANDED DNA ANTIBODY; ESTROGEN; GAMMA INTERFERON; GLUCOCORTICOID; GLUTAMATE DECARBOXYLASE 65; HISTONE ANTIBODY; INSULIN; INTERLEUKIN 1; INTERLEUKIN 4; INTERLEUKIN 6; THYROGLOBULIN ANTIBODY; VITAMIN D;

ANOVULATION; ANTIPHOSPHOLIPID SYNDROME; AUTOIMMUNE DISEASE; AUTOIMMUNE POLYENDOCRINOPATHY; AUTOIMMUNE THYROIDITIS; AUTOIMMUNITY; CHRONIC DISEASE; CYTOKINE RELEASE; DERMATOMYOSITIS; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPERANDROGENISM; HYPERGLYCEMIA; HYPOTHYROIDISM; IMMUNE DYSREGULATION; IMMUNOTHERAPY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; KIDNEY MICROSOME; LIVER MICROSOME; OBESITY; OVARY POLYCYSTIC DISEASE; POLYMYOSITIS; PREMATURE OVARIAN FAILURE; REVIEW; RHEUMATOID ARTHRITIS; SCLERODERMA; SMOOTH MUSCLE FIBER; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; TH1 CELL; TH2 CELL; VITAMIN D DEFICIENCY;

AUTOANTIBODIES; AUTOIMMUNE DISEASES; AUTOIMMUNITY; FEMALE; HUMANS; HYPERANDROGENISM; POLYCYSTIC OVARY SYNDROME;

EID: 77956441089     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejim.2010.06.008     Document Type: Review

References (55)

1. I.F. Stein, and N.L. Leventhal Amenorrhea associated with bilateral polycystic ovaries Am J Obstet Gynecol 29 1935 181 191
2. M. Asuncion, R.M. Calvo, J.L. San Millán, J. Sancho, S. Avila, and H.F. Escobar-Morreale A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain J Clin Endocrinol Metab 85 2000 2434 2438
3. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Hum Reprod 19 2004 41
4. L. Ibañez, J. Dimartino-Nardi, N. Potau, and P. Saenger Premature adrenarche - normal variant or forerunner of adult disease? Endocr Rev 21 2000 671 696
5. L. Anttila, K. Karjala, R.A. Penttilä, K. Ruutiainen, and U. Ekblad Polycystic ovaries in women with gestational diabetes Obstet Gynecol 92 1998 13 16
6. J. Holte, G. Gennarelli, L. Wide, H. Lithell, and C. Berne High prevalence of polycystic ovaries and associated clinical, endocrine, and metabolic features in women with previous gestational diabetes mellitus J Clin Endocrinol Metab 83 1998 1143 1150
7. R.S. Legro, D. Driscoll, J.F. Strauss 3rd, J. Fox, and A. Dunaif Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome Proc Natl Acad Sci USA 95 1998 14956 14960
8. M. Kahsar-Miller, C. Nixon, L.R. Boots, R.C. Go, and R. Azziz Prevalence of the polycystic ovary syndrome (PCOS) among first degree relatives of patients with PCOS Fertil Steril 75 2001 53 58
9. C.M. DeUgarte, A.A. Bartolucci, and R. Azziz Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment Fertil Steril 83 2005 1454 1460
10. R.S. Legro, D. Finegood, and A. Dunaif A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome J Clin Endocrinol Metab 83 1998 2694 2698
11. R.S. Legro, A.R. Kunselman, W.C. Dodson, and A. Dunaif Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women J Clin Endocrinol Metab 84 1999 165 169
12. D.A. Ehrmann, K. Kasza, R. Azziz, R.S. Legro, and M.N. Ghazii Effects of race and family history of type 2 diabetes on metabolic status of women with polycystic ovary syndrome J Clin Endocrinol Metab 90 2005 66 71
13. P. Hardiman, O.S. Pillay, and W. Atiorno Polycystic ovary syndrome and endometrial carcinoma Lancet 361 2003 1810 1812
14. R.S. Legro Polycystic ovary syndrome and cardiovascular disease: a premature association? Endocr Rev 24 2003 302 312
15. S. Dejager, C. Pichard, P. Giral, E. Bruckert, M.C. Federspield, and I. Beucler Smaller LDL particle size in women with polycystic ovary syndrome compared to controls Clin Endocrinol 54 2001 455 462
16. R.G. Lahita Gender disparity in systemic lupus erythematosus, thoughts after the 8th International Congress on Systemic Lupus Erythematosus, Shanghai, China, 2007 J Clin Rheumatol 14 3 2008 185 187
17. J. Rovenský, R. Imrich, I. Lazúrová, and J. Payer Rheumatic Diseases and Klinefelter's Syndrome Ann N Y Acad Sci 1193 1 2010 1 9
18. J. Li, J.M. Su, and X.J. Zeng Is primary biliary cirrhosis another example of an immunemediated complication of Klinefelter syndrome? J Clin Rheumatol 10 2004 286 287
19. M.W. Angstwurm, R. Gartner, and H.W. Ziegler-Heitbrock Cyclic plasma IL-6 levels during normal menstrual cycle Cytokine 9 1997 370 374
20. E. Wehr, S. Pilz, N. Schweighofer, A. Giuliani, D. Kopera, and T.R. Pieber Interaction of 25-hydroxyvitamin D levels with metabolic characteristics in polycystic ovary syndrome Bone 44 2009 357 358
21. M.F. Holick Vitamin D: a millenium perspective J Cell Biochem 88 2003 296 307
22. A. Zittermann Vitamin D in preventive medicine: are we ignoring the evidence? Br J Nutr 89 2003 552 572
23. R.O. Escárcega, M. García-Carrasco, S. Fuentes-Alexandro, L.J. Jara, J. Rojas-Rodriquez, and L.E. Escobar-Linares Insulin resistance, chronic inflammatory state and the link with systemic lupus erythematosus- related coronary disease Autoimmun Rev 6 2006 48 53
24. P.H. Dessein, and B.I. Joffe Insulin resistance and impaired beta cell functions in reumathoid arthritis Arthritis Rheum 54 2006 2765 2775
25. H. Orbach, G. Zandman-Goddard, H. Amital, V. Barak, Z. Szekanecz, and G. Szucs Novel biomarkers in autoimmune diseases: prolactin, ferritin, vitamin D, and TPA levels in autoimmune diseases Ann NY Acad Sci 1109 2007 385 400
26. K. Hefler-Frischmuth, K. Walch, W. Huebl, K. Baumuehlner, C. Tempfer, and L. Hefler Serologic markers of autoimmunity in women with the polycystic ovary syndrome Fertil Steril 92 5 2009 60
27. K. Reimand, I. Talja, K. Metskula, U. Kadastik, K. Matt, and R. Uibo Autoantibody studies of female patients with reproductive failure J Reprod Immunol 51 2001 167 176
28. R.G. Lahita The role of sex hormones in systemic lupus erythematosus Curr Opin Rheumatol 11 1999 352 356
29. O.E. Janssen, N. Mehlmauer, S. Hahn, A.H. Offner, and R. Gärtner High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome Eur J Endocrinol 150 2004 363 369
30. S.H. Lee, M.R. Kim, J.H. Kim, H.S. Kwon, K.H. Yoon, and H.Y. Son A patient with combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2 Gynecol Endocrinol 23 2007 252 256
31. P. Fénichel, B. Gobert, Y. Carré, P. Barbarino-Monnier, and S. Hiéronimus Polycystic ovary syndrome in autoimmune disease Lancet 353 1999 2210
32. N. Rojanski, D. Roll, and D. Meirow Polycystic ovary syndrome. An autoimmune disease? J Reprod Med 42 1997 325 328
33. J.L. Luborsky, S. Shatavi, P. Adamczyk, C. Chiong, B. Llanes, and J. Lafniztzegger Polycystic ovary syndrome and ovarian autoimmunity - assessment of ovarian antibodies by EIA J Reprod Immunol 42 1999 79 84
34. B. Gobert, P. Barbarino-Monnnier, F. Guillet-Rosso, M.C. Bene, and G.C. Faure Anti-ovary antibodies after attempts at human in vitro fertilization induced by follicular puncture rather than hormonal stimulation J Reprod Fertil 96 1992 213 221
35. Y. Suh Autoimmune oophoritis-a case report J Korean Med Sci 7 1992 284 290
36. R.N. Lonsdale, P.F. Roberts, and J.E. Trowell Autoimmune oophoritis associated with polycystic ovaries Histopathology 19 1991 77 81
37. C.J. van Gelderen, and M.L. Gomes dos Santos Polycystic ovarian syndrome. Evidence for an autoimmune mechanism in some cases J Reprod Med 38 1993 381 386
38. K. Haller, Ch. Mathieu, K. Rull, K. Matt, M.C. Béné, and R. Uibo IgG, IgA and IgM antibodies against FSH: serological markers of pathogenic autoimmunity or of normal immunoregulation? Am J Reprod Immunol 54 2005 262 269
39. J.R. Palacio, A. Iborra, Z. Ulcova-Gallova, R. Badia, and P. Martínez The presence of antibodies to oxidative modified proteins in serum from polycystic ovary syndrome patients Clin Exp Immunol 144 2006 217 222
40. N. Gleicher, A. El-Roeiy, E. Confino, and J. Friberg Is endometriosis an autoimmune disease? Obstet Gynecol 70 1987 115 122
41. J.N. Anasti Premature ovarian failure: an update Fertil Steril 70 1998 1 15
42. S.N. Kalantaridou, S.R. Davis, and L.M. Nelson Premature ovarian failure Endocrinol Metab Clin North Am 27 1998 989 1006
43. W.J. Irvine, M.W. Cahn, L. Scarth, F.O. Kolb, M. Hartog, and R.I. Bayliss Immunological aspects of premature ovarian failure associated with Addison's disease Lancet 2 7574 1968 883 887
44. A.M. Vasquez, and F.M. Kenny Ovarian failure and antiovarian antibodies in association with hypoparathyroidism, moniliasis, and Addison's and Hashimoto's disease Obstet Gynecol 41 1973 3
45. K.S.K. Tung, and C.Y. Lu Immunological basis of reproductive failure F.T. Krans, I. Danijanov, N. Kaufman, Pathology of Reproductive Failure 1991 Williams & Wilkins Baltimore 308 333
46. J.L. Luborsky, I. Visintin, S. Boyers, T. Asari, B. Caldwell, and A. DeCherney Ovarian antibodies detected by immobilized antigen immunoassay in patients with premature ovarian failure J Clin Endocrinol Metab 70 1990 69 75
47. N.J. Wheatcroft, A.A. Toogood, T.C. Li, I.D. Cooke, and A.P. Weetman Detection of antibodies to ovarian antigens in women with premature failure Clin Exp Immunol 96 1994 122 128
48. B. Corenblum, T. Rowe, and P.J. Taylor High doses, short term glucocorticoids for the treatment of infertility resulting from premature ovarian failure Fertil Steril 59 1993 988 991
49. Y. Xia, C.C. Zhou, S.M. Ramin, and R.E. Kellems Angiotensin receptors, autoimmunity, and preeclampsia J Immunol 15 179(6) 2007 3391 3395
50. Cervera R, Balasch J. Autoimmunity and recurrent pregnancy losses. Clin Rev Allergy Immunol 2009, doi:10.1007/s12016-009-8179-1.
51. E. Konova, T. Aleksovska, M. Atanasova, M. Georgieva, K. Todorova, and T. Lukanov Anti-elastin antibodies and elastin turnover in normal pregnancy and recurrent pregnancy loss Am J Reprod Immunol 61 2 2009 167 174
52. G. Matarese, G. De Placido, Y. Nikas, and C. Alviggi Pathogenesis of endometriosis: natural immunity dysfunction or autoimmune disease? Trends Mol Med 9 2003 223 228
53. Y.Y. Hsieh, C.C. Chang, F.J. Tsai, C.C. Lin, L.S. Yeh, and C.H. Tsai Tumor necrosis factor-alpha-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas Fertil Steril 82 2004 1177 1181
54. H.R. Barber Present status of tumor immunology in clinical gynecology Am J Reprod Immunol 20 1989 140 146
55. J.L. Luborsky, P. Thiruppathi, B. Rivnay, R. Roussev, C. Coulam, and E. Radwanska Evidence for different aetiologies of low estradiol response to FSH: age-related accelerated luteinization of follicles or presence of ovarian antibodies? Hum Reprod 17 2002 2641 2649