Anti-Elastin antibodies and elastin turnover in normal pregnancy and recurrent pregnancy loss

American Journal of Reproductive Immunology

Volumn 61, Issue 2, 2009, Pages 167-174

  Konova, Emiliana ^a   Aleksovska, Tania ^a   Atanasova, Milena ^a   Georgieva, Miglena ^b   Todorova, Katia ^c   Lukanov, Tzvetan ^a   Shoenfeld, Yehuda ^d,e  

^a MEDICAL UNIVERSITY PLEVEN   (Bulgaria)

^b Clinical Institute for Reproductive Medicine   (Bulgaria)

^c UNIVERSITY HOSPITAL ALEXANDROVSKA   (Bulgaria)

^d SHEBA MEDICAL CENTER   (Israel)

^e TEL AVIV UNIVERSITY   (Israel)

Author keywords

A elastin; Anti tropoelastin antibody; ELISA; Synthesis degradation ratio; Tropoelastin

Indexed keywords

ALPHA ELASTIN ANTIBODY; ELASTIN; ELASTIN ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PROTEIN ANTIBODY; TROPOELASTIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; PATHOGENESIS; PREGNANCY; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; RECURRENT DISEASE; SPONTANEOUS ABORTION;

ABORTION, HABITUAL; ADOLESCENT; ADULT; AUTOANTIBODIES; ELASTIN; FEMALE; HUMANS; PREGNANCY; PROSPECTIVE STUDIES; TROPOELASTIN; YOUNG ADULT;

EID: 58249144215     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2008.00678.x     Document Type: Article

References (34)

1. Vrhosvski B, Weiss AS: Biochemistry of tropoelastin. Eur J Biochem 1998; 258:1-18.
2. Mecham RP, Davis EC: Elastic fiber structure and assembly. In Extracellular Matrix Assembly, PD Yurchenko, DE Birk, RP Mecham (eds). San Diego, Academic Press, 1994, pp 281-310.
3. Robert L, Robert AM, Jacotot B: Elastin-elastase-atherosclerosis revisited. Atherosclerosis 1998; 140:281-295.
4. Metaxa-Mariatou V, McGvigan CJ, Robertson K, Stewart C, Cameron IT, Campbell S: Elastin distribution in the myometrial and vascular smooth muscle of the human uterus. Mol Hum Reprod 2002; 8:559-565.
5. Zheng WQ, Ma R, Zheng JM, Gong ZJ: Elastin distribution in the normal uterus, uterine leiomyomas, adenomyosis and adenomyomas: A comparison. Anal Quant Cytol Histol 2006; 28: 115-120.
6. Gunja-Smith Z, Woessner JF: Content of the collagen and elastin cross-links pyridinoline and the desmosines in the human uterus in various reproductive states. Am J Obstet Gynecol 1985; 153:92-95.
7. Albert EN, Pease DC: An electron microscopic study of uterine arteries during pregnancy. Am J Anat 1968; 123:165-194.
8. Abilez O, Alsac J, Heikkinen M, Nezhat CH, Zarin C, Nezhat C: Adaptative media remodeling of the uterine artery during pregnancy. Fertil Steril 2005; 84:S399.
9. Sharrow L, Tinker D, Davidson JM, Rucker RB: Accumulation and regulation of elastin in the rat uterus. Proc Soc Exp Biol Med 1989; 192:121-126.
10. Stein F, Pezess MP, Robert L, Poullain MA: Antielastin antibodies in normal and pathological human sera. Nature 1965; 207:312-313.
11. Baydanoff S, Nicoloff G, Alexiev C: Age-related changes in the level of circulating elastin-derived peptides in serum from normal and atherosclerotic subjects. Atherosclerosis 1987; 66:163-168.
12. Colburn KK, Kelly GT, Malto MC, Sandberg LB, Boucek RJ: Serum anti-tropo:aNti-alpha-elastin antibody ratio assessing elastin turnover in scleroderma. Clin Rheumatol 1992; 11:206-210.
13. Colburn KK, Malto MC, Sandberg LB, Langa-Shariffi E, Green LM: Abnormalities of serum anti-elastin antibodies in patients with polymyalgia rheumatica. J Musculoskeletal Pain 2006; 14:21-26.
14. Colburn KK, Langga-Shariffi E, Kelly GT, Malto MC, Sandberg LB, Baydanoff S, Green LM: Abnormalities of serum antielastin antibodies in connective tissue diseases. J Investig Med 2003; 51:104-109.
15. Daskalova M, Taskov H, Dimitrova E, Baydanoff S: Humoral and cellular immune response to elastin in patients with systemic sclerosis. Autoimmunity 1996; 25:233-241.
16. Daskalova M, Hristov D, Gospodinov D, Mihov M, Baydanoff ST: Humoral and cell-mediated immune response to elastin antigen in patients with SLE. Dermatol Venerol 1994; 32:24-29.
17. Woessner JF, Brewer TH: Formation and breakdown of collagen and elastin in the human uterus during pregnancy and post-partum involution. Biochem J 1963; 89:75-82.
18. Wei SM, Katona E, Fachet J, Fülöp T Jr, Robert L, Jacob MP: Epitope specificity of monoclonal and polyclonal antibodies to human elastin. Int Arch Allergy Immunol 1998; 115:33-41.
19. Hinek A, Rabinovitch M, Keeley F, Okamura-Oho Y, Callahan J: The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase. J Clin Invest 1993; 91:1198-1205.
20. Privitera S, Prody CA, Callahan JW, Hinek A: The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein. J Biol Chem 1998; 273:6319-6326.
21. Labat-Robert J: Cell-matrix iRteractions in aging: role of receptors and matricryptins. Ageing Res Rev 2004; 3:233-247.
22. Fulop T Jr, Jacob MP, Khalil A, Wallach J, Robert L: Biological effects of elastin peptides. Pathol Biol 1998; 46:497-506.
23. Debret R, Antonicelli F, Theill A, Hornebeck W, Bernard P, Guenounou M, Le Naour R: Elastin-derived peptides induce a T-helper type 1 polarization of human blood lymphocytes. Arterioscler Thromb Vasc Biol 2005; 25:1353-1358.
24. Wegmann TG, Lin H, Guilbert L, Mosmann TR: Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a TH2 phenomenon. Immunol Today 1993; 14:353-356.
25. Konova E, Atanasova M, Stoykov SV, Velkova A, Shoenfeld Y: Idiotypic and anti-idiotypic elastin autoantibodies: Implications for IVIG and pregnancy loss. J Autoimmun 2007; 28:46-54.
26. Shapiro SD, Campbell EJ, Welgus HG, Senior RM: Elastin degradation by mononuclear phagocytes. Ann N Y Acad Sci 1991; 624:69-80.
27. Werb Z, Banda MJ, McKerrow JH, Sandhaus RA: Elastases and elastin degradation. J Invest Dermatol 1982; 79(Suppl. 1):154-159.
28. Reboud-Ravaux M: Elastase inhibitors. J Soc Biol 2001; 195:143-150.
29. Gupta AK, Gebhardt S, Hillermann R, Holzgreve W, Hahn S: Analysis of plasma elastase levels in early and late onset preeclampsia. Arch Gynecol Obstet 2006; 273:239-242.
30. Weir PE: Immunofluorescent studies of the uteroplacental arteries in normal pregnancy. Br J Obstet Gynaecol 1981; 88:301-307.
31. Wells M, Bennett J, Bulmer JN, Jackson P, Holgate CS: Complement component deposition in uteroplacental (spiral) arteries in normal human pregnancy. J Reprod Immunol 1987; 12:125-135.
32. Cunningham DS, Tichenor JR: Decay-accelerating factor protects human trophoblast from complement-mediated attack. Clin Immunol Immunopathol 1995; 74:156-161.
33. Tedesco F, Narchi G, Radillo O, Meri S, Ferrone S, Betterle C: Susceptibility of human trophoblast to killing by human complement and the role of the complement regulatory proteins. J Immunol 1993; 151:1562-1570.
34. Salmon JE, Girardi G, Holers VM: Complement activation as a mediator of antiphospholipid antibody induced pregnancy loss and thrombosis. Ann Rheum Dis 2002; 61:46-50.