메뉴 건너뛰기




Volumn 78, Issue 4, 2010, Pages 321-333

Hippocampus development and function: Role of epigenetic factors and implications for cognitive disease

Author keywords

Chromatin remodelling; Cognitive disease; Epigenetics; Hippocampus; Intellectual disability; Learning and memory; Mental retardation

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA METHYLTRANSFERASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 77956415882     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2010.01503.x     Document Type: Review
Times cited : (39)

References (139)
  • 1
    • 77952678006 scopus 로고    scopus 로고
    • Epigenetic control of neural precursor cell fate during development
    • Hirabayashi Y, Gotoh Y. Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci 2010, 11(6):377-388.
    • (2010) Nat Rev Neurosci , vol.11 , Issue.6 , pp. 377-388
    • Hirabayashi, Y.1    Gotoh, Y.2
  • 2
  • 3
    • 57049151436 scopus 로고    scopus 로고
    • Epigenetic principles and mechanisms underlying nervous system functions in health and disease
    • Mehler MF. Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol 2008, 86(4):305-341.
    • (2008) Prog Neurobiol , vol.86 , Issue.4 , pp. 305-341
    • Mehler, M.F.1
  • 4
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000, 403(6765):41-45.
    • (2000) Nature , vol.403 , Issue.6765 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 5
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007, 128(4):693-705.
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 6
    • 1642376040 scopus 로고    scopus 로고
    • Molecular and comparative genetics of mental retardation
    • Inlow JK, Restifo LL. Molecular and comparative genetics of mental retardation. Genetics 2004, 166(2):835-881.
    • (2004) Genetics , vol.166 , Issue.2 , pp. 835-881
    • Inlow, J.K.1    Restifo, L.L.2
  • 7
    • 67649921127 scopus 로고    scopus 로고
    • The genetic landscape of intellectual disability arising from chromosome X
    • Gecz J, Shoubridge C, Corbett M. The genetic landscape of intellectual disability arising from chromosome X. Trends Genet 2009, 25(7):308-316.
    • (2009) Trends Genet , vol.25 , Issue.7 , pp. 308-316
    • Gecz, J.1    Shoubridge, C.2    Corbett, M.3
  • 8
    • 73849109194 scopus 로고    scopus 로고
    • X-linked intellectual disability: unique vulnerability of the male genome
    • Stevenson RE, Schwartz CE. X-linked intellectual disability: unique vulnerability of the male genome. Dev Disabil Res Rev 2009, 15(4):361-368.
    • (2009) Dev Disabil Res Rev , vol.15 , Issue.4 , pp. 361-368
    • Stevenson, R.E.1    Schwartz, C.E.2
  • 9
    • 77952887052 scopus 로고    scopus 로고
    • Disruption of the epigenetic code: an emerging mechanism in mental retardation
    • van Bokhoven H, Kramer JM. Disruption of the epigenetic code: an emerging mechanism in mental retardation. Neurobiol Dis 2010, 39(1):3-12.
    • (2010) Neurobiol Dis , vol.39 , Issue.1 , pp. 3-12
    • van Bokhoven, H.1    Kramer, J.M.2
  • 10
    • 0031469495 scopus 로고    scopus 로고
    • Early specification and autonomous development of cortical fields in the mouse hippocampus
    • Tole S, Christian C, Grove EA. Early specification and autonomous development of cortical fields in the mouse hippocampus. Development 1997, 124(24):4959-4970.
    • (1997) Development , vol.124 , Issue.24 , pp. 4959-4970
    • Tole, S.1    Christian, C.2    Grove, E.A.3
  • 11
    • 0025088799 scopus 로고
    • Prolonged sojourn of developing pyramidal cells in the intermediate zone of the hippocampus and their settling in the stratum pyramidale
    • Altman J, Bayer SA. Prolonged sojourn of developing pyramidal cells in the intermediate zone of the hippocampus and their settling in the stratum pyramidale. J Comp Neurol 1990, 301(3):343-364.
    • (1990) J Comp Neurol , vol.301 , Issue.3 , pp. 343-364
    • Altman, J.1    Bayer, S.A.2
  • 12
    • 0018679456 scopus 로고
    • The mode of migration of neurons to the hippocampus: a Golgi and electron microscopic analysis in foetal rhesus monkey
    • Nowakowski RS, Rakic P. The mode of migration of neurons to the hippocampus: a Golgi and electron microscopic analysis in foetal rhesus monkey. J Neurocytol 1979, 8(6):697-718.
    • (1979) J Neurocytol , vol.8 , Issue.6 , pp. 697-718
    • Nowakowski, R.S.1    Rakic, P.2
  • 13
    • 0033499932 scopus 로고    scopus 로고
    • The establishment of GABAergic and glutamatergic synapses on CA1 pyramidal neurons is sequential and correlates with the development of the apical dendrite
    • Tyzio R, Represa A, Jorquera I. The establishment of GABAergic and glutamatergic synapses on CA1 pyramidal neurons is sequential and correlates with the development of the apical dendrite. J Neurosci 1999, 19(23):10372-10382.
    • (1999) J Neurosci , vol.19 , Issue.23 , pp. 10372-10382
    • Tyzio, R.1    Represa, A.2    Jorquera, I.3
  • 14
    • 0013807956 scopus 로고
    • Time of neuron origin in the hippocampal region. An autoradiographic study in the mouse
    • Oct (Suppl 2):
    • Angevine JB. Time of neuron origin in the hippocampal region. An autoradiographic study in the mouse. Exp Neurol 1965, 1-70. Oct (Suppl 2):
    • (1965) Exp Neurol , pp. 1-70
    • Angevine, J.B.1
  • 15
    • 0016266374 scopus 로고
    • Hippocampal development in the rat: cytogenesis and morphogenesis examined with autoradiography and low level X irradiation
    • Bayer SA, Altman J. Hippocampal development in the rat: cytogenesis and morphogenesis examined with autoradiography and low level X irradiation. J Comp Neurol 1974, 158(1):55-80.
    • (1974) J Comp Neurol , vol.158 , Issue.1 , pp. 55-80
    • Bayer, S.A.1    Altman, J.2
  • 16
    • 0034517638 scopus 로고    scopus 로고
    • Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons
    • Pleasure SJ, Anderson S, Hevner R. Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron 2000, 28(3):727-740.
    • (2000) Neuron , vol.28 , Issue.3 , pp. 727-740
    • Pleasure, S.J.1    Anderson, S.2    Hevner, R.3
  • 17
    • 0036979204 scopus 로고    scopus 로고
    • Early sequential formation of functional GABAA and glutamatergic synapses on CA1 interneurons of the rat foetal hippocampus
    • Hennou S, Khalilov I, Diabira D. Early sequential formation of functional GABAA and glutamatergic synapses on CA1 interneurons of the rat foetal hippocampus. Eur J Neurosci 2002, 16(2):197-208.
    • (2002) Eur J Neurosci , vol.16 , Issue.2 , pp. 197-208
    • Hennou, S.1    Khalilov, I.2    Diabira, D.3
  • 18
    • 0029119311 scopus 로고
    • Postnatal development of CA3 pyramidal neurons and their afferents in the Ammon's horn of rhesus monkeys
    • Seress L, Ribak CE. Postnatal development of CA3 pyramidal neurons and their afferents in the Ammon's horn of rhesus monkeys. Hippocampus 1995, 5(3):217-231.
    • (1995) Hippocampus , vol.5 , Issue.3 , pp. 217-231
    • Seress, L.1    Ribak, C.E.2
  • 19
    • 0019433958 scopus 로고
    • Development of the mossy fibers of the dentate gyrus: I. A light and electron microscopic study of the mossy fibers and their expansions
    • Amaral DG, Dent JA. Development of the mossy fibers of the dentate gyrus: I. A light and electron microscopic study of the mossy fibers and their expansions. J Comp Neurol 1981, 195(1):51-86.
    • (1981) J Comp Neurol , vol.195 , Issue.1 , pp. 51-86
    • Amaral, D.G.1    Dent, J.A.2
  • 20
    • 0025088801 scopus 로고
    • Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods
    • Altman J, Bayer SA. Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods. J Comp Neurol 1990, 301(3):365-381.
    • (1990) J Comp Neurol , vol.301 , Issue.3 , pp. 365-381
    • Altman, J.1    Bayer, S.A.2
  • 21
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • Altman J, Das GD. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 1965, 124(3):319-335.
    • (1965) J Comp Neurol , vol.124 , Issue.3 , pp. 319-335
    • Altman, J.1    Das, G.D.2
  • 22
    • 77952887349 scopus 로고    scopus 로고
    • Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind
    • Hsieh J, Eisch AJ. Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind. Neurobiol Dis 2010, 39(1):73-84.
    • (2010) Neurobiol Dis , vol.39 , Issue.1 , pp. 73-84
    • Hsieh, J.1    Eisch, A.J.2
  • 23
    • 0242363254 scopus 로고    scopus 로고
    • The long-term potential of LTP
    • Malenka RC. The long-term potential of LTP. Nat Rev 2003, 4(11):923-926.
    • (2003) Nat Rev , vol.4 , Issue.11 , pp. 923-926
    • Malenka, R.C.1
  • 24
    • 0346728801 scopus 로고    scopus 로고
    • Long-term potentiation and memory
    • Lynch MA. Long-term potentiation and memory. Physiol Rev 2004, 84(1):87-136.
    • (2004) Physiol Rev , vol.84 , Issue.1 , pp. 87-136
    • Lynch, M.A.1
  • 25
    • 0032742810 scopus 로고    scopus 로고
    • Toward a molecular explanation for long-term potentiation
    • Sweatt JD. Toward a molecular explanation for long-term potentiation. Learn Mem 1999, 6(5):399-416.
    • (1999) Learn Mem , vol.6 , Issue.5 , pp. 399-416
    • Sweatt, J.D.1
  • 26
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: an embarrassment of riches
    • Malenka RC, Bear MF. LTP and LTD: an embarrassment of riches. Neuron 2004, 44(1):5-21.
    • (2004) Neuron , vol.44 , Issue.1 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 27
    • 47549109984 scopus 로고    scopus 로고
    • Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory
    • Barrett RM, Wood MA. Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory. Learn Mem 2008, 15(7):460-467.
    • (2008) Learn Mem , vol.15 , Issue.7 , pp. 460-467
    • Barrett, R.M.1    Wood, M.A.2
  • 28
    • 68649088591 scopus 로고    scopus 로고
    • Regulation of chromatin structure in memory formation
    • Roth TL, Sweatt JD. Regulation of chromatin structure in memory formation. Curr Opin Neurobiol 2009, 19(3):336-342.
    • (2009) Curr Opin Neurobiol , vol.19 , Issue.3 , pp. 336-342
    • Roth, T.L.1    Sweatt, J.D.2
  • 29
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 2006, 31(2):89-97.
    • (2006) Trends Biochem Sci , vol.31 , Issue.2 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 30
    • 0037146613 scopus 로고    scopus 로고
    • Transient forebrain ischemia alters the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus
    • Jung BP, Zhang G, Ho W. Transient forebrain ischemia alters the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus. Neuroscience 2002, 115(2):515-524.
    • (2002) Neuroscience , vol.115 , Issue.2 , pp. 515-524
    • Jung, B.P.1    Zhang, G.2    Ho, W.3
  • 31
    • 33645218438 scopus 로고    scopus 로고
    • A family of human zinc finger proteins that bind methylated DNA and repress transcription
    • Filion GJ, Zhenilo S, Salozhin S. A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol Cell Biol 2006, 26(1):169-181.
    • (2006) Mol Cell Biol , vol.26 , Issue.1 , pp. 169-181
    • Filion, G.J.1    Zhenilo, S.2    Salozhin, S.3
  • 32
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69(6):915-926.
    • (1992) Cell , vol.69 , Issue.6 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 33
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99(3):247-257.
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3
  • 34
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 2010, 13(4):423-430.
    • (2010) Nat Neurosci , vol.13 , Issue.4 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3
  • 35
    • 34147186795 scopus 로고    scopus 로고
    • Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation
    • Golshani P, Hutnick L, Schweizer F. Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus Relat Syst 2005, 3(3):227-233.
    • (2005) Thalamus Relat Syst , vol.3 , Issue.3 , pp. 227-233
    • Golshani, P.1    Hutnick, L.2    Schweizer, F.3
  • 36
    • 67650711853 scopus 로고    scopus 로고
    • DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation
    • Hutnick LK, Golshani P, Namihira M. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Human Mol Genet 2009, 18(15):2875-2888.
    • (2009) Human Mol Genet , vol.18 , Issue.15 , pp. 2875-2888
    • Hutnick, L.K.1    Golshani, P.2    Namihira, M.3
  • 37
    • 0033547330 scopus 로고    scopus 로고
    • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
    • Xu GL, Bestor TH, Bourc'his D. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 1999, 402(6758):187-191.
    • (1999) Nature , vol.402 , Issue.6758 , pp. 187-191
    • Xu, G.L.1    Bestor, T.H.2    Bourc'his, D.3
  • 38
    • 33744920106 scopus 로고    scopus 로고
    • Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus
    • Levenson JM, Roth TL, Lubin FD. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J Biol Chem 2006, 281(23):15763-15773.
    • (2006) J Biol Chem , vol.281 , Issue.23 , pp. 15763-15773
    • Levenson, J.M.1    Roth, T.L.2    Lubin, F.D.3
  • 39
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron 2007, 53(6):857-869.
    • (2007) Neuron , vol.53 , Issue.6 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 40
    • 38349044361 scopus 로고    scopus 로고
    • Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation
    • Nelson ED, Kavalali ET, Monteggia LM. Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. J Neurosci 2008, 28(2):395-406.
    • (2008) J Neurosci , vol.28 , Issue.2 , pp. 395-406
    • Nelson, E.D.1    Kavalali, E.T.2    Monteggia, L.M.3
  • 41
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin FD, Roth TL, Sweatt JD. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 2008, 28(42):10576-10586.
    • (2008) J Neurosci , vol.28 , Issue.42 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 42
    • 0037636512 scopus 로고    scopus 로고
    • Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
    • Zhao X, Ueba T, Christie BR. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A 2003, 100(11):6777-6782.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.11 , pp. 6777-6782
    • Zhao, X.1    Ueba, T.2    Christie, B.R.3
  • 43
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen RZ, Akbarian S, Tudor M. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 2001, 27(3):327-331.
    • (2001) Nat Genet , vol.27 , Issue.3 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3
  • 44
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy J, Hendrich B, Holmes M. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 2001, 27(3):322-326.
    • (2001) Nat Genet , vol.27 , Issue.3 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3
  • 45
    • 0037130455 scopus 로고    scopus 로고
    • Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3
    • Shahbazian M, Young J, Yuva-Paylor L. Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron 2002, 35(2):243-254.
    • (2002) Neuron , vol.35 , Issue.2 , pp. 243-254
    • Shahbazian, M.1    Young, J.2    Yuva-Paylor, L.3
  • 46
    • 8444253290 scopus 로고    scopus 로고
    • Mild overexpression of MeCP2 causes a progressive neurological disorder in mice
    • Collins AL, Levenson JM, Vilaythong AP. Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Hum Mol Genet 2004, 13(21):2679-2689.
    • (2004) Hum Mol Genet , vol.13 , Issue.21 , pp. 2679-2689
    • Collins, A.L.1    Levenson, J.M.2    Vilaythong, A.P.3
  • 47
    • 0027963287 scopus 로고
    • Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents
    • Belichenko PV, Oldfors A, Hagberg B. Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents. Neuroreport 1994, 5(12):1509-1513.
    • (1994) Neuroreport , vol.5 , Issue.12 , pp. 1509-1513
    • Belichenko, P.V.1    Oldfors, A.2    Hagberg, B.3
  • 48
    • 0029059624 scopus 로고
    • Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome
    • Bauman ML, Kemper TL, Arin DM. Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome. Neurology 1995, 45(8):1581-1586.
    • (1995) Neurology , vol.45 , Issue.8 , pp. 1581-1586
    • Bauman, M.L.1    Kemper, T.L.2    Arin, D.M.3
  • 49
    • 67649487935 scopus 로고    scopus 로고
    • Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations
    • Chapleau CA, Calfa GD, Lane MC. Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations. Neurobiol Dis 2009, 35(2):219-233.
    • (2009) Neurobiol Dis , vol.35 , Issue.2 , pp. 219-233
    • Chapleau, C.A.1    Calfa, G.D.2    Lane, M.C.3
  • 50
    • 34250333455 scopus 로고    scopus 로고
    • Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons
    • Smrt RD, Eaves-Egenes J, Barkho BZ. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiol Dis 2007, 27(1):77-89.
    • (2007) Neurobiol Dis , vol.27 , Issue.1 , pp. 77-89
    • Smrt, R.D.1    Eaves-Egenes, J.2    Barkho, B.Z.3
  • 51
    • 65349122404 scopus 로고    scopus 로고
    • Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks
    • Belichenko PV, Wright EE, Belichenko NP. Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks. J Comp Neurol 2009, 514(3):240-258.
    • (2009) J Comp Neurol , vol.514 , Issue.3 , pp. 240-258
    • Belichenko, P.V.1    Wright, E.E.2    Belichenko, N.P.3
  • 52
    • 33749590330 scopus 로고    scopus 로고
    • Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation
    • Zhou Z, Hong EJ, Cohen S. Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron 2006, 52(2):255-269.
    • (2006) Neuron , vol.52 , Issue.2 , pp. 255-269
    • Zhou, Z.1    Hong, E.J.2    Cohen, S.3
  • 53
    • 29144440149 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome
    • Asaka Y, Jugloff DG, Zhang L. Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis 2006, 21(1):217-227.
    • (2006) Neurobiol Dis , vol.21 , Issue.1 , pp. 217-227
    • Asaka, Y.1    Jugloff, D.G.2    Zhang, L.3
  • 54
    • 30644479042 scopus 로고    scopus 로고
    • Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome
    • Moretti P, Levenson JM, Battaglia F. Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome. J Neurosci 2006, 26(1):319-327.
    • (2006) J Neurosci , vol.26 , Issue.1 , pp. 319-327
    • Moretti, P.1    Levenson, J.M.2    Battaglia, F.3
  • 55
    • 34748831111 scopus 로고    scopus 로고
    • MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number
    • Chao HT, Zoghbi HY, Rosenmund C. MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron 2007, 56(1):58-65.
    • (2007) Neuron , vol.56 , Issue.1 , pp. 58-65
    • Chao, H.T.1    Zoghbi, H.Y.2    Rosenmund, C.3
  • 56
    • 33645882216 scopus 로고    scopus 로고
    • MeCP2-dependent transcriptional repression regulates excitatory neurotransmission
    • Nelson ED, Kavalali ET, Monteggia LM. MeCP2-dependent transcriptional repression regulates excitatory neurotransmission. Curr Biol 2006, 16(7):710-716.
    • (2006) Curr Biol , vol.16 , Issue.7 , pp. 710-716
    • Nelson, E.D.1    Kavalali, E.T.2    Monteggia, L.M.3
  • 57
    • 45749111428 scopus 로고    scopus 로고
    • The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits
    • Allan AM, Liang X, Luo Y. The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits. Human Mol Genet 2008, 17(13):2047-2057.
    • (2008) Human Mol Genet , vol.17 , Issue.13 , pp. 2047-2057
    • Allan, A.M.1    Liang, X.2    Luo, Y.3
  • 58
    • 73349092441 scopus 로고    scopus 로고
    • Histones: annotating chromatin
    • Campos EI, Reinberg D. Histones: annotating chromatin. Annu Rev Genet 2009, 43:559-599.
    • (2009) Annu Rev Genet , vol.43 , pp. 559-599
    • Campos, E.I.1    Reinberg, D.2
  • 59
    • 33744793463 scopus 로고    scopus 로고
    • ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning
    • Chwang WB, O'Riordan KJ, Levenson JM. ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning. Learn Mem 2006, 13(3):322-328.
    • (2006) Learn Mem , vol.13 , Issue.3 , pp. 322-328
    • Chwang, W.B.1    O'Riordan, K.J.2    Levenson, J.M.3
  • 60
    • 36249006058 scopus 로고    scopus 로고
    • The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation.
    • Chwang WB, Arthur JS, Schumacher A. The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation. J Neurosci 2007, 27(46):12732-12742.
    • (2007) J Neurosci , vol.27 , Issue.46 , pp. 12732-12742
    • Chwang, W.B.1    Arthur, J.S.2    Schumacher, A.3
  • 61
    • 70350437289 scopus 로고    scopus 로고
    • Protein phosphatase 1 regulates the histone code for long-term memory
    • Koshibu K, Graff J, Beullens M. Protein phosphatase 1 regulates the histone code for long-term memory. J Neurosci 2009, 29(41):13079-13089.
    • (2009) J Neurosci , vol.29 , Issue.41 , pp. 13079-13089
    • Koshibu, K.1    Graff, J.2    Beullens, M.3
  • 62
    • 70349194448 scopus 로고    scopus 로고
    • PolyADP-ribosylation is required for long-term memory formation in mammals
    • Goldberg S, Visochek L, Giladi E. PolyADP-ribosylation is required for long-term memory formation in mammals. J Neurochem 2009, 111(1):72-79.
    • (2009) J Neurochem , vol.111 , Issue.1 , pp. 72-79
    • Goldberg, S.1    Visochek, L.2    Giladi, E.3
  • 63
    • 77949357100 scopus 로고    scopus 로고
    • Histone methylation regulates memory formation
    • Gupta S, Kim SY, Artis S. Histone methylation regulates memory formation. J Neurosci 2010, 30(10):3589-3599.
    • (2010) J Neurosci , vol.30 , Issue.10 , pp. 3589-3599
    • Gupta, S.1    Kim, S.Y.2    Artis, S.3
  • 64
    • 42149117852 scopus 로고    scopus 로고
    • Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos
    • Lin W, Zhang Z, Srajer G. Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos. Dev Dyn 2008, 237(4):928-940.
    • (2008) Dev Dyn , vol.237 , Issue.4 , pp. 928-940
    • Lin, W.1    Zhang, Z.2    Srajer, G.3
  • 65
    • 34247646897 scopus 로고    scopus 로고
    • Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos
    • Bu P, Evrard YA, Lozano G. Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol Cell Biol 2007, 27(9):3405-3416.
    • (2007) Mol Cell Biol , vol.27 , Issue.9 , pp. 3405-3416
    • Bu, P.1    Evrard, Y.A.2    Lozano, G.3
  • 66
    • 17644445419 scopus 로고    scopus 로고
    • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
    • Yao TP, Oh SP, Fuchs M. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 1998, 93(3):361-372.
    • (1998) Cell , vol.93 , Issue.3 , pp. 361-372
    • Yao, T.P.1    Oh, S.P.2    Fuchs, M.3
  • 67
    • 0033134766 scopus 로고    scopus 로고
    • Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis
    • Oike Y, Takakura N, Hata A. Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis. Blood 1999, 93(9):2771-2779.
    • (1999) Blood , vol.93 , Issue.9 , pp. 2771-2779
    • Oike, Y.1    Takakura, N.2    Hata, A.3
  • 68
    • 43649104766 scopus 로고    scopus 로고
    • Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice
    • Maurice T, Duclot F, Meunier J. Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice. Neuropsychopharmacology 2008, 33(7):1584-1602.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.7 , pp. 1584-1602
    • Maurice, T.1    Duclot, F.2    Meunier, J.3
  • 69
    • 2942731425 scopus 로고    scopus 로고
    • CBP histone acetyltransferase activity is a critical component of memory consolidation
    • Korzus E, Rosenfeld MG, Mayford M. CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron 2004, 42(6):961-972.
    • (2004) Neuron , vol.42 , Issue.6 , pp. 961-972
    • Korzus, E.1    Rosenfeld, M.G.2    Mayford, M.3
  • 70
    • 2942705826 scopus 로고    scopus 로고
    • Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
    • Alarcon JM, Malleret G, Touzani K. Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 2004, 42(6):947-959.
    • (2004) Neuron , vol.42 , Issue.6 , pp. 947-959
    • Alarcon, J.M.1    Malleret, G.2    Touzani, K.3
  • 71
    • 0037099413 scopus 로고    scopus 로고
    • G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
    • Tachibana M, Sugimoto K, Nozaki M. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 2002, 16(14):1779-1791.
    • (2002) Genes Dev , vol.16 , Issue.14 , pp. 1779-1791
    • Tachibana, M.1    Sugimoto, K.2    Nozaki, M.3
  • 72
    • 0037599617 scopus 로고    scopus 로고
    • NSD1 is essential for early post-implantation development and has a catalytically active SET domain
    • Rayasam GV, Wendling O, Angrand PO. NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J 2003, 22(12):3153-3163.
    • (2003) EMBO J , vol.22 , Issue.12 , pp. 3153-3163
    • Rayasam, G.V.1    Wendling, O.2    Angrand, P.O.3
  • 73
    • 71149121303 scopus 로고    scopus 로고
    • Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex
    • Schaefer A, Sampath SC, Intrator A. Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron 2009, 64(5):678-691.
    • (2009) Neuron , vol.64 , Issue.5 , pp. 678-691
    • Schaefer, A.1    Sampath, S.C.2    Intrator, A.3
  • 74
    • 77951885885 scopus 로고    scopus 로고
    • Reduced exploration, increased anxiety, and altered social behavior: autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice
    • Balemans MC, Huibers MM, Eikelenboom NW. Reduced exploration, increased anxiety, and altered social behavior: autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice. Behav Brain Res 2010, 208(1):47-55.
    • (2010) Behav Brain Res , vol.208 , Issue.1 , pp. 47-55
    • Balemans, M.C.1    Huibers, M.M.2    Eikelenboom, N.W.3
  • 75
    • 33746563985 scopus 로고    scopus 로고
    • Loss-of-function mutations in euchromatin histone methyl transferase 1 (EHMT1) cause the 9q34 subtelomeric deletion syndrome
    • Kleefstra T, Brunner HG, Amiel J. Loss-of-function mutations in euchromatin histone methyl transferase 1 (EHMT1) cause the 9q34 subtelomeric deletion syndrome. Am J Hum Genet 2006, 79(2):370-377.
    • (2006) Am J Hum Genet , vol.79 , Issue.2 , pp. 370-377
    • Kleefstra, T.1    Brunner, H.G.2    Amiel, J.3
  • 76
    • 68349116164 scopus 로고    scopus 로고
    • The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain
    • Zhao X, DA D, Lim WK. The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell 2009, 17(2):210-221.
    • (2009) Dev Cell , vol.17 , Issue.2 , pp. 210-221
    • Zhao, X.1    DA, D.2    Lim, W.K.3
  • 77
    • 0029022770 scopus 로고
    • Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
    • Petrij F, Giles RH, Dauwerse HG. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 1995, 376(6538):348-351.
    • (1995) Nature , vol.376 , Issue.6538 , pp. 348-351
    • Petrij, F.1    Giles, R.H.2    Dauwerse, H.G.3
  • 78
    • 20144386935 scopus 로고    scopus 로고
    • Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease
    • Roelfsema JH, White SJ, Ariyürek Y. Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease. Am J Hum Genet 2005, 76(4):572-580.
    • (2005) Am J Hum Genet , vol.76 , Issue.4 , pp. 572-580
    • Roelfsema, J.H.1    White, S.J.2    Ariyürek, Y.3
  • 79
    • 33745896544 scopus 로고    scopus 로고
    • Differential role for CBP and p300 CREB-binding domain in motor skill learning
    • Oliveira AM, Abel T, Brindle PK. Differential role for CBP and p300 CREB-binding domain in motor skill learning. Behav Neurosci 2006, 120(3):724-729.
    • (2006) Behav Neurosci , vol.120 , Issue.3 , pp. 724-729
    • Oliveira, A.M.1    Abel, T.2    Brindle, P.K.3
  • 80
    • 34748917182 scopus 로고    scopus 로고
    • Transgenic mice expressing an inhibitory truncated form of p300 exhibit long-term memory deficits
    • Oliveira AM, Wood MA, McDonough CB. Transgenic mice expressing an inhibitory truncated form of p300 exhibit long-term memory deficits. Learn Mem 2007, 14(9):564-572.
    • (2007) Learn Mem , vol.14 , Issue.9 , pp. 564-572
    • Oliveira, A.M.1    Wood, M.A.2    McDonough, C.B.3
  • 81
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A, Sananbenesi F, Wang X. Recovery of learning and memory is associated with chromatin remodelling. Nature 2007, 447(7141):178-182.
    • (2007) Nature , vol.447 , Issue.7141 , pp. 178-182
    • Fischer, A.1    Sananbenesi, F.2    Wang, X.3
  • 82
    • 67649342616 scopus 로고    scopus 로고
    • Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function
    • Akhtar MW, Raingo J, Nelson ED. Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function. J Neurosci 2009, 29(25):8288-8297.
    • (2009) J Neurosci , vol.29 , Issue.25 , pp. 8288-8297
    • Akhtar, M.W.1    Raingo, J.2    Nelson, E.D.3
  • 83
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • Guan JS, Haggarty SJ, Giacometti E. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 2009, 459(7243):55-60.
    • (2009) Nature , vol.459 , Issue.7243 , pp. 55-60
    • Guan, J.S.1    Haggarty, S.J.2    Giacometti, E.3
  • 84
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • Clapier CR, Cairns BR. The biology of chromatin remodeling complexes. Annu Rev Biochem 2009, 78:273-304.
    • (2009) Annu Rev Biochem , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 85
    • 77954218952 scopus 로고    scopus 로고
    • Structures of SWI/SNF chromatin remodeling complexes and the mechanistic implications in transcription
    • Tang L, Nogales E. Structures of SWI/SNF chromatin remodeling complexes and the mechanistic implications in transcription. Prog Biophys Mol Biol 2010, 102:122-128.
    • (2010) Prog Biophys Mol Biol , vol.102 , pp. 122-128
    • Tang, L.1    Nogales, E.2
  • 86
    • 14944359718 scopus 로고    scopus 로고
    • The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis
    • Berube NG, Mangelsdorf M, Jagla M. The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clinical Invest 2005, 115(2):258-267.
    • (2005) J Clinical Invest , vol.115 , Issue.2 , pp. 258-267
    • Berube, N.G.1    Mangelsdorf, M.2    Jagla, M.3
  • 87
    • 58149391969 scopus 로고    scopus 로고
    • Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53
    • Seah C, Levy MA, Jiang Y. Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci 2008, 28(47):12570-12580.
    • (2008) J Neurosci , vol.28 , Issue.47 , pp. 12570-12580
    • Seah, C.1    Levy, M.A.2    Jiang, Y.3
  • 88
    • 33947266958 scopus 로고    scopus 로고
    • Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues
    • Hurd EA, Capers PL, Blauwkamp MN. Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues. Mamm Genome 2007, 18(2):94-104.
    • (2007) Mamm Genome , vol.18 , Issue.2 , pp. 94-104
    • Hurd, E.A.1    Capers, P.L.2    Blauwkamp, M.N.3
  • 89
    • 65549097631 scopus 로고    scopus 로고
    • Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome
    • Layman WS, McEwen DP, Beyer LA. Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome. Hum Mol Genet 2009, 18(11):1909-1923.
    • (2009) Hum Mol Genet , vol.18 , Issue.11 , pp. 1909-1923
    • Layman, W.S.1    McEwen, D.P.2    Beyer, L.A.3
  • 90
    • 0030916337 scopus 로고    scopus 로고
    • Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition
    • van der Horst GT, van Steeg H, Berg RJ. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 1997, 89(3):425-435.
    • (1997) Cell , vol.89 , Issue.3 , pp. 425-435
    • van der Horst, G.T.1    van Steeg, H.2    Berg, R.J.3
  • 91
    • 0035818496 scopus 로고    scopus 로고
    • Early postnatal ataxia and abnormal cerebellar development in mice lacking xeroderma pigmentosum group A and Cockayne syndrome group B DNA repair genes
    • Murai M, Enokido Y, Inamura N. Early postnatal ataxia and abnormal cerebellar development in mice lacking xeroderma pigmentosum group A and Cockayne syndrome group B DNA repair genes. Proc Natl Acad Sci U S A 2001, 98(23):13379-13384.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.23 , pp. 13379-13384
    • Murai, M.1    Enokido, Y.2    Inamura, N.3
  • 92
    • 30044445350 scopus 로고    scopus 로고
    • Brg1 is required for murine neural stem cell maintenance and gliogenesis
    • Matsumoto S, Banine F, Struve J. Brg1 is required for murine neural stem cell maintenance and gliogenesis. Dev Biol 2006, 289(2):372-383.
    • (2006) Dev Biol , vol.289 , Issue.2 , pp. 372-383
    • Matsumoto, S.1    Banine, F.2    Struve, J.3
  • 93
    • 22944448744 scopus 로고    scopus 로고
    • Geminin regulates neuronal differentiation by antagonizing Brg1 activity
    • Seo S, Herr A, Lim JW. Geminin regulates neuronal differentiation by antagonizing Brg1 activity. Genes Dev 2005, 19(14):1723-1734.
    • (2005) Genes Dev , vol.19 , Issue.14 , pp. 1723-1734
    • Seo, S.1    Herr, A.2    Lim, J.W.3
  • 94
    • 13444263724 scopus 로고    scopus 로고
    • The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD
    • Seo S, Richardson GA, Kroll KL. The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD. Development 2005, 132(1):105-115.
    • (2005) Development , vol.132 , Issue.1 , pp. 105-115
    • Seo, S.1    Richardson, G.A.2    Kroll, K.L.3
  • 95
    • 34447249019 scopus 로고    scopus 로고
    • An essential switch in subunit composition of a chromatin remodeling complex during neural development
    • Lessard J, Wu JI, Ranish JA. An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron 2007, 55(2):201-215.
    • (2007) Neuron , vol.55 , Issue.2 , pp. 201-215
    • Lessard, J.1    Wu, J.I.2    Ranish, J.A.3
  • 96
    • 34748887795 scopus 로고    scopus 로고
    • Regulation of dendritic development by neuron-specific chromatin remodeling complexes
    • Wu JI, Lessard J, Olave IA. Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 2007, 56(1):94-108.
    • (2007) Neuron , vol.56 , Issue.1 , pp. 94-108
    • Wu, J.I.1    Lessard, J.2    Olave, I.A.3
  • 97
    • 24144490659 scopus 로고    scopus 로고
    • Chromatin, DNA methylation and neuron gene regulation-the purpose of the package
    • Sharma RP, Grayson DR, Guidotti A. Chromatin, DNA methylation and neuron gene regulation-the purpose of the package. J Psychiatry Neurosci 2005, 30(4):257-263.
    • (2005) J Psychiatry Neurosci , vol.30 , Issue.4 , pp. 257-263
    • Sharma, R.P.1    Grayson, D.R.2    Guidotti, A.3
  • 98
    • 0028939603 scopus 로고
    • Mutations in a putative global transcriptional regulator cause X-linked mental retardation with α-thalassemia (ATR-X syndrome)
    • Gibbons RJ, Picketts DJ, Villard L. Mutations in a putative global transcriptional regulator cause X-linked mental retardation with α-thalassemia (ATR-X syndrome). Cell 1995, 80(6):837-845.
    • (1995) Cell , vol.80 , Issue.6 , pp. 837-845
    • Gibbons, R.J.1    Picketts, D.J.2    Villard, L.3
  • 99
    • 4444239112 scopus 로고    scopus 로고
    • Mutations in a new member of the chromodomain gene family cause CHARGE syndrome
    • Vissers LE, van Ravenswaaij CM, Admiraal R. Mutations in a new member of the chromodomain gene family cause CHARGE syndrome. Nat Genet 2004, 36(9):955-957.
    • (2004) Nat Genet , vol.36 , Issue.9 , pp. 955-957
    • Vissers, L.E.1    van Ravenswaaij, C.M.2    Admiraal, R.3
  • 100
    • 0033912653 scopus 로고    scopus 로고
    • Manitoba aboriginal kindred with original cerebro-oculo- facio-skeletal syndrome has a mutation in the Cockayne syndrome group B (CSB) gene
    • Meira LB, Graham JM, Greenberg CR. Manitoba aboriginal kindred with original cerebro-oculo- facio-skeletal syndrome has a mutation in the Cockayne syndrome group B (CSB) gene. Am J Hum Genet 2000, 66(4):1221-1228.
    • (2000) Am J Hum Genet , vol.66 , Issue.4 , pp. 1221-1228
    • Meira, L.B.1    Graham, J.M.2    Greenberg, C.R.3
  • 101
    • 0038353760 scopus 로고    scopus 로고
    • Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation
    • Kalscheuer VM, Tao J, Donnelly A. Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation. Am J Hum Genet 2003, 72(6):1401-1411.
    • (2003) Am J Hum Genet , vol.72 , Issue.6 , pp. 1401-1411
    • Kalscheuer, V.M.1    Tao, J.2    Donnelly, A.3
  • 102
    • 56349150405 scopus 로고    scopus 로고
    • Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1
    • Kameshita I, Sekiguchi M, Hamasaki D. Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1. Biochem Biophys Res Commun 2008, 377(4):1162-1167.
    • (2008) Biochem Biophys Res Commun , vol.377 , Issue.4 , pp. 1162-1167
    • Kameshita, I.1    Sekiguchi, M.2    Hamasaki, D.3
  • 103
    • 26444495179 scopus 로고    scopus 로고
    • CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome
    • Mari F, Azimonti S, Bertani I. CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome. Hum Mol Genet 2005, 14(14):1935-1946.
    • (2005) Hum Mol Genet , vol.14 , Issue.14 , pp. 1935-1946
    • Mari, F.1    Azimonti, S.2    Bertani, I.3
  • 104
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE, Van den Veyver IB, Wan M. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 1999, 23(2):185-188.
    • (1999) Nat Genet , vol.23 , Issue.2 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3
  • 105
    • 0034661112 scopus 로고    scopus 로고
    • BCoR, a novel corepressor involved in BCL-6 repression
    • Huynh KD, Fischle W, Verdin E. BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev 2000, 14(14):1810-1823.
    • (2000) Genes Dev , vol.14 , Issue.14 , pp. 1810-1823
    • Huynh, K.D.1    Fischle, W.2    Verdin, E.3
  • 106
    • 12144287606 scopus 로고    scopus 로고
    • Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR
    • Ng D, Thakker N, Corcoran CM. Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR. Nat Genet 2004, 36(4):411-416.
    • (2004) Nat Genet , vol.36 , Issue.4 , pp. 411-416
    • Ng, D.1    Thakker, N.2    Corcoran, C.M.3
  • 107
    • 34249715325 scopus 로고    scopus 로고
    • Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor
    • Sanchez C, Sanchez I, Demmers JA. Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Mol Cell Proteomics 2007, 6(5):820-834.
    • (2007) Mol Cell Proteomics , vol.6 , Issue.5 , pp. 820-834
    • Sanchez, C.1    Sanchez, I.2    Demmers, J.A.3
  • 108
    • 17144374869 scopus 로고    scopus 로고
    • Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage
    • Wood MA, Kaplan MP, Park A. Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage. Learn Mem 2005, 12(2):111-119.
    • (2005) Learn Mem , vol.12 , Issue.2 , pp. 111-119
    • Wood, M.A.1    Kaplan, M.P.2    Park, A.3
  • 109
    • 0346969980 scopus 로고    scopus 로고
    • Dendrite development regulated by CREST, a calcium-regulated transcriptional activator
    • Aizawa H, Hu SC, Bobb K. Dendrite development regulated by CREST, a calcium-regulated transcriptional activator. Science 2004, 303(5655):197-202.
    • (2004) Science , vol.303 , Issue.5655 , pp. 197-202
    • Aizawa, H.1    Hu, S.C.2    Bobb, K.3
  • 110
    • 55049121548 scopus 로고    scopus 로고
    • A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression
    • Qiu Z, Ghosh A. A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression. Neuron 2008, 60(5):775-787.
    • (2008) Neuron , vol.60 , Issue.5 , pp. 775-787
    • Qiu, Z.1    Ghosh, A.2
  • 111
    • 34248222814 scopus 로고    scopus 로고
    • Developmental regulation of Eed complex composition governs a switch in global histone modification in brain
    • Kim SY, Levenson JM, Korsmeyer S. Developmental regulation of Eed complex composition governs a switch in global histone modification in brain. J Biol Chem 2007, 282(13):9962-9972.
    • (2007) J Biol Chem , vol.282 , Issue.13 , pp. 9962-9972
    • Kim, S.Y.1    Levenson, J.M.2    Korsmeyer, S.3
  • 112
    • 66049101024 scopus 로고    scopus 로고
    • Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development
    • Montgomery RL, Hsieh J, Barbosa AC. Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci U S A 2009, 106(19):7876-7881.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.19 , pp. 7876-7881
    • Montgomery, R.L.1    Hsieh, J.2    Barbosa, A.C.3
  • 113
    • 40749130484 scopus 로고    scopus 로고
    • Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation
    • Froyen G, Corbett M, Vandewalle J. Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation. Am J Hum Genet 2008, 82(2):432-443.
    • (2008) Am J Hum Genet , vol.82 , Issue.2 , pp. 432-443
    • Froyen, G.1    Corbett, M.2    Vandewalle, J.3
  • 114
    • 15044354179 scopus 로고    scopus 로고
    • Characterization of E3 histone, a novel testis ubiquitin protein ligase which ubiquitinates histones
    • Liu Z, Oughtred R, Wing SS. Characterization of E3 histone, a novel testis ubiquitin protein ligase which ubiquitinates histones. Mol Cell Biol 2005, 25(7):2819-2831.
    • (2005) Mol Cell Biol , vol.25 , Issue.7 , pp. 2819-2831
    • Liu, Z.1    Oughtred, R.2    Wing, S.S.3
  • 115
    • 48349122949 scopus 로고    scopus 로고
    • Mediator links epigenetic silencing of neuronal gene expression with X-linked mental retardation
    • Ding N, Zhou H, Esteve PO. Mediator links epigenetic silencing of neuronal gene expression with X-linked mental retardation. Mol Cell 2008, 31(3):347-359.
    • (2008) Mol Cell , vol.31 , Issue.3 , pp. 347-359
    • Ding, N.1    Zhou, H.2    Esteve, P.O.3
  • 116
    • 59249093974 scopus 로고    scopus 로고
    • The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator
    • Knuesel MT, Meyer KD, Donner AJ. The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. Mol Cell Biol 2009, 29(3):650-661.
    • (2009) Mol Cell Biol , vol.29 , Issue.3 , pp. 650-661
    • Knuesel, M.T.1    Meyer, K.D.2    Donner, A.J.3
  • 117
    • 34047153922 scopus 로고    scopus 로고
    • A recurrent mutation in MED12 leading to R961W causes Opitz-Kaveggia syndrome
    • Risheg H, Graham JM, Clark RD. A recurrent mutation in MED12 leading to R961W causes Opitz-Kaveggia syndrome. Nat Genet 2007, 39(4):451-453.
    • (2007) Nat Genet , vol.39 , Issue.4 , pp. 451-453
    • Risheg, H.1    Graham, J.M.2    Clark, R.D.3
  • 118
    • 34447342555 scopus 로고    scopus 로고
    • The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene
    • Schwartz CE, Tarpey PS, Lubs HA. The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene. J Med Genet 2007, 44(7):472-477.
    • (2007) J Med Genet , vol.44 , Issue.7 , pp. 472-477
    • Schwartz, C.E.1    Tarpey, P.S.2    Lubs, H.A.3
  • 119
    • 12144288309 scopus 로고    scopus 로고
    • Paradoxical NSD1 mutations in Beckwith-Wiedemann syndrome and 11p15 anomalies in Sotos syndrome
    • Baujat G, Rio M, Rossignol S. Paradoxical NSD1 mutations in Beckwith-Wiedemann syndrome and 11p15 anomalies in Sotos syndrome. Am J Hum Genet 2004, 74(4):715-720.
    • (2004) Am J Hum Genet , vol.74 , Issue.4 , pp. 715-720
    • Baujat, G.1    Rio, M.2    Rossignol, S.3
  • 120
    • 0037217478 scopus 로고    scopus 로고
    • NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes
    • Douglas J, Hanks S, Temple IK. NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes. Am J Hum Genet 2003, 72(1):132-143.
    • (2003) Am J Hum Genet , vol.72 , Issue.1 , pp. 132-143
    • Douglas, J.1    Hanks, S.2    Temple, I.K.3
  • 121
    • 18544384537 scopus 로고    scopus 로고
    • Haploinsufficiency of NSD1 causes Sotos syndrome
    • Kurotaki N, Imaizumi K, Harada N. Haploinsufficiency of NSD1 causes Sotos syndrome. Nat Genet 2002, 30(4):365-366.
    • (2002) Nat Genet , vol.30 , Issue.4 , pp. 365-366
    • Kurotaki, N.1    Imaizumi, K.2    Harada, N.3
  • 122
    • 0036668638 scopus 로고    scopus 로고
    • P21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells
    • Li F, Adam L, Vadlamudi RK. p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells. EMBO Rep 2002, 3(8):767-773.
    • (2002) EMBO Rep , vol.3 , Issue.8 , pp. 767-773
    • Li, F.1    Adam, L.2    Vadlamudi, R.K.3
  • 123
    • 58049087185 scopus 로고    scopus 로고
    • Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1)
    • Asrar S, Meng Y, Zhou Z. Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1). Neuropharmacology 2009, 56(1):73-80.
    • (2009) Neuropharmacology , vol.56 , Issue.1 , pp. 73-80
    • Asrar, S.1    Meng, Y.2    Zhou, Z.3
  • 124
    • 16344390935 scopus 로고    scopus 로고
    • A GIT1/PIX/Rac/ PAK signaling module regulates spine morphogenesis and synapse formation through MLC
    • Zhang H, Webb DJ, Asmussen H. A GIT1/PIX/Rac/ PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J Neurosci 2005, 25(13):3379-3388.
    • (2005) J Neurosci , vol.25 , Issue.13 , pp. 3379-3388
    • Zhang, H.1    Webb, D.J.2    Asmussen, H.3
  • 125
    • 77952553303 scopus 로고    scopus 로고
    • Alteration of working memory but not in anxiety or stress response in p300/CBP associated factor (PCAF) histone acetylase knockout mice bred on a C57BL/6 background
    • Duclot F, Jacquet C, Gongora C. Alteration of working memory but not in anxiety or stress response in p300/CBP associated factor (PCAF) histone acetylase knockout mice bred on a C57BL/6 background. Neurosci Lett 2010, 475(3):179-183.
    • (2010) Neurosci Lett , vol.475 , Issue.3 , pp. 179-183
    • Duclot, F.1    Jacquet, C.2    Gongora, C.3
  • 126
    • 77950893589 scopus 로고    scopus 로고
    • A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation
    • Kleine-Kohlbrecher D, Christensen J, Vandamme J. A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation. Mol Cell 2010, 38(2):165-178.
    • (2010) Mol Cell , vol.38 , Issue.2 , pp. 165-178
    • Kleine-Kohlbrecher, D.1    Christensen, J.2    Vandamme, J.3
  • 127
    • 26944461197 scopus 로고    scopus 로고
    • Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate
    • Laumonnier F, Holbert S, Ronce N. Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate. J Med Genet 2005, 42(10):780-786.
    • (2005) J Med Genet , vol.42 , Issue.10 , pp. 780-786
    • Laumonnier, F.1    Holbert, S.2    Ronce, N.3
  • 128
    • 33847661648 scopus 로고    scopus 로고
    • Altered neurodevelopment associated with mutations of RSK2: a morphometric MRI study of Coffin-Lowry syndrome
    • Kesler SR, Simensen RJ, Voeller K. Altered neurodevelopment associated with mutations of RSK2: a morphometric MRI study of Coffin-Lowry syndrome. Neurogenetics 2007, 8(2):143-147.
    • (2007) Neurogenetics , vol.8 , Issue.2 , pp. 143-147
    • Kesler, S.R.1    Simensen, R.J.2    Voeller, K.3
  • 129
    • 33846437448 scopus 로고    scopus 로고
    • Deletion of the Coffin-Lowry syndrome gene Rsk2 in mice is associated with impaired spatial learning and reduced control of exploratory behavior
    • Poirier R, Jacquot S, Vaillend C. Deletion of the Coffin-Lowry syndrome gene Rsk2 in mice is associated with impaired spatial learning and reduced control of exploratory behavior. Behav Genet 2007, 37(1):31-50.
    • (2007) Behav Genet , vol.37 , Issue.1 , pp. 31-50
    • Poirier, R.1    Jacquot, S.2    Vaillend, C.3
  • 130
    • 0033529706 scopus 로고    scopus 로고
    • Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3
    • Sassone-Corsi P, Mizzen CA, Cheung P. Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3. Science 1999, 285(5429):886-891.
    • (1999) Science , vol.285 , Issue.5429 , pp. 886-891
    • Sassone-Corsi, P.1    Mizzen, C.A.2    Cheung, P.3
  • 131
    • 0029832136 scopus 로고    scopus 로고
    • Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome
    • Trivier E, De Cesare D, Jacquot S. Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome. Nature 1996, 384(6609):567-570.
    • (1996) Nature , vol.384 , Issue.6609 , pp. 567-570
    • Trivier, E.1    De Cesare, D.2    Jacquot, S.3
  • 132
    • 19944430270 scopus 로고    scopus 로고
    • Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation
    • Jensen LR, Amende M, Gurok U. Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation. Am J Hum Genet 2005, 76(2):227-236.
    • (2005) Am J Hum Genet , vol.76 , Issue.2 , pp. 227-236
    • Jensen, L.R.1    Amende, M.2    Gurok, U.3
  • 133
    • 34249900454 scopus 로고    scopus 로고
    • The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
    • Tahiliani M, Mei P, Fang R. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 2007, 447(7144):601-605.
    • (2007) Nature , vol.447 , Issue.7144 , pp. 601-605
    • Tahiliani, M.1    Mei, P.2    Fang, R.3
  • 134
    • 34547732455 scopus 로고    scopus 로고
    • Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly
    • Field M, Tarpey PS, Smith R. Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly. Am J Hum Genet 2007, 81(2):367-374.
    • (2007) Am J Hum Genet , vol.81 , Issue.2 , pp. 367-374
    • Field, M.1    Tarpey, P.S.2    Smith, R.3
  • 135
    • 18744393073 scopus 로고    scopus 로고
    • Mutations in PHF6 are associated with Borjeson-Forssman-Lehmann syndrome
    • Lower KM, Turner G, Kerr BA. Mutations in PHF6 are associated with Borjeson-Forssman-Lehmann syndrome. Nat Genet 2002, 32(4):661-665.
    • (2002) Nat Genet , vol.32 , Issue.4 , pp. 661-665
    • Lower, K.M.1    Turner, G.2    Kerr, B.A.3
  • 136
    • 9144230687 scopus 로고    scopus 로고
    • Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation
    • Shoichet SA, Hoffmann K, Menzel C. Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation. Am J Hum Genet 2003, 73(6):1341-1354.
    • (2003) Am J Hum Genet , vol.73 , Issue.6 , pp. 1341-1354
    • Shoichet, S.A.1    Hoffmann, K.2    Menzel, C.3
  • 137
    • 2342535716 scopus 로고    scopus 로고
    • Zinc finger 81 (ZNF81) mutations associated with X-linked mental retardation
    • Kleefstra T, Yntema HG, Oudakker AR. Zinc finger 81 (ZNF81) mutations associated with X-linked mental retardation. J Med Genet 2004, 41(5):394-399.
    • (2004) J Med Genet , vol.41 , Issue.5 , pp. 394-399
    • Kleefstra, T.1    Yntema, H.G.2    Oudakker, A.R.3
  • 138
    • 31544453949 scopus 로고    scopus 로고
    • ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation
    • Lugtenberg D, Yntema HG, Banning MJ. ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation. Am J Hum Genet 2006, 78(2):265-278.
    • (2006) Am J Hum Genet , vol.78 , Issue.2 , pp. 265-278
    • Lugtenberg, D.1    Yntema, H.G.2    Banning, M.J.3
  • 139
    • 66749148353 scopus 로고    scopus 로고
    • A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation
    • Tarpey PS, Smith R, Pleasance E. A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. Nat Genet 2009, 41(5):535-543.
    • (2009) Nat Genet , vol.41 , Issue.5 , pp. 535-543
    • Tarpey, P.S.1    Smith, R.2    Pleasance, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.