Strategy for the identification of GPR23/LPA4 receptor agonists and inverse agonists

Assay and Drug Development Technologies

Volumn 8, Issue 4, 2010, Pages 459-470

  Wong, Soo Hang ^a   Mallari, Rommel ^a   Graham, Melissa ^a   Atangan, Larissa ^a   Lu, Shu Chen ^a   Zhao, Xiaoning ^a   Gu, Wei ^a   Lee, Paul H ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; DOXYCYCLINE; G PROTEIN COUPLED RECEPTOR 23 AGONIST; G PROTEIN COUPLED RECEPTOR 23 ANTAGONIST; LYSOPHOSPHATIDIC ACID; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG MECHANISM; FEMALE; HIGH THROUGHPUT SCREENING; IC 50; NONHUMAN; PROTEIN BINDING;

ANIMALS; BETA-LACTAMASES; CALCIUM; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; DRUG AGONISM; DRUG INVERSE AGONISM; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; LYSOPHOSPHOLIPIDS; PHOSPHOLIPIDS; RECEPTORS, LYSOPHOSPHATIDIC ACID; RECEPTORS, PURINERGIC P2;

EID: 77956408084     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2009.0261     Document Type: Article

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